How structural subtleties lead to molecular diversity for the type III polyketide synthases

Structural and biochemical characterization of the plant type III polyketide synthases of the liverwort Marchantia paleacea

(2018) Hai-Na Yu et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Tropinone synthesis via an atypical polyketide synthase and P450-mediated cyclization

(2018) Matthew A. Bedewitz et al.   Nature Communications

2-Alkylquinolone alkaloid biosynthesis in the medicinal plantEvodia rutaecarpainvolves collaboration of two novel type III polyketide synthases

(2017) Takashi Matsui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular architectures of benzoic acid-specific type III polyketide synthases

(2017) Charles Stewart et al.   Acta Crystallographica Section D-Structural Biology

Structural basis for olivetolic acid formation by a polyketide cyclase fromCannabis sativa

(2016) Xinmei Yang et al.   FEBS Journal

PqsBC, a Condensing Enzyme in the Biosynthesis of thePseudomonas aeruginosaQuinolone Signal

(2016) Steffen Lorenz Drees et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploiting the Biosynthetic Potential of Type III Polyketide Synthases

(2016) Yan Lim et al.   MOLECULES

Synthesis of Unnatural 2-Substituted Quinolones and 1,3-Diketones by a Member of Type III Polyketide Synthases from Huperzia serrata

(2016) Juan Wang et al.   ORGANIC LETTERS

Two polyketide synthases are necessary for 4-hydroxy-5-methylcoumarin biosynthesis inGerbera hybrida

(2016) Milla Pietiäinen et al.   PLANT JOURNAL

A Novel Class of Plant Type III Polyketide Synthase Involved in Orsellinic Acid Biosynthesis from Rhododendron dauricum

(2016) Futoshi Taura et al.   Frontiers in Plant Science

PqsE of Pseudomonas aeruginosa Acts as Pathway-Specific Thioesterase in the Biosynthesis of Alkylquinolone Signaling Molecules

(2015) Steffen Lorenz Drees et al.   CHEMISTRY & BIOLOGY

Synthetic Polyketide Enzymology: Platform for Biosynthesis of Antimicrobial Polyketides

(2015) Maybelle Kho Go et al.   ACS Catalysis

Expression, purification and crystallization of a plant polyketide cyclase fromCannabis sativa

(2015) Xinmei Yang et al.   Acta Crystallographica Section F-Structural Biology Communications

The End of an Old Hypothesis: The Pseudomonas Signaling Molecules 4-Hydroxy-2-Alkylquinolines Derive from Fatty Acids, Not 3-Ketofatty Acids

(2013) Carlos Eduardo Dulcey et al.   CHEMISTRY & BIOLOGY

Identification and Characterization of a Type III Polyketide Synthase Involved in Quinolone Alkaloid Biosynthesis fromAegle marmelosCorrea

(2013) Mohankumar Saraladevi Resmi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cloning and Structure-Function Analyses of Quinolone- and Acridone-producing Novel Type III Polyketide Synthases fromCitrus microcarpa

(2013) Takahiro Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vitro formation of the anthranoid scaffold by cell-free extracts from yeast-extract-treated Cassia bicapsularis cell cultures

(2013) Iman A.M. Abdel-Rahman et al.   PHYTOCHEMISTRY

Microbial biosynthesis of the anticoagulant precursor 4-hydroxycoumarin

(2013) Yuheng Lin et al.   Nature Communications

PhyscomitrellaPpORS, Basal to Plant Type III Polyketide Synthases in Phylogenetic Trees, Is a Very Long Chain 2′-Oxoalkylresorcinol Synthase

(2012) Sun Young Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Benzophenone synthase from Garcinia mangostana L. pericarps

(2012) Natsajee Nualkaew et al.   PHYTOCHEMISTRY

Identification of olivetolic acid cyclase from Cannabis sativa reveals a unique catalytic route to plant polyketides

(2012) S. J. Gagne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enzymatic formation of an aromatic dodecaketide by engineered plant polyketide synthase

(2011) Kiyofumi Wanibuchi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of unnatural alkaloid scaffolds by exploiting plant polyketide synthase

(2011) H. Morita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression, purification and crystallization of a plant type III polyketide synthase that produces diarylheptanoids

(2010) Hiroyuki Morita et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Structural and Biochemical Elucidation of Mechanism for Decarboxylative Condensation of β-Keto Acid by Curcumin Synthase

(2010) Yohei Katsuyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and function of the chalcone synthase superfamily of plant type III polyketide synthases

(2010) Ikuro Abe et al.   NATURAL PRODUCT REPORTS

Alkylresorcylic acid synthesis by type III polyketide synthases from rice Oryza sativa

(2010) Miku Matsuzawa et al.   PHYTOCHEMISTRY

Structural basis for the one-pot formation of the diarylheptanoid scaffold by curcuminoid synthase from Oryza sativa

(2010) H. Morita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of curcuminoid synthase CUS from Oryza sativa

(2010) Ken-ichi Miyazono et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Novel type III polyketide synthases fromAloe arborescens

(2009) Yuusuke Mizuuchi et al.   FEBS Journal

Characterization of olivetol synthase, a polyketide synthase putatively involved in cannabinoid biosynthetic pathway

(2009) Futoshi Taura et al.   FEBS LETTERS

Identification and characterization of multiple curcumin synthases from the herbCurcuma longa

(2009) Yohei Katsuyama et al.   FEBS LETTERS

A Single Amino Acid Substitution Converts Benzophenone Synthase into Phenylpyrone Synthase

(2009) Tim Klundt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Curcuminoid Biosynthesis by Two Type III Polyketide Synthases in the HerbCurcuma longa

(2009) Yohei Katsuyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enzymatic Formation of Unnatural Novel Chalcone, Stilbene, and Benzophenone Scaffolds by Plant Type III Polyketide Synthase

(2009) She-Po Shi et al.   ORGANIC LETTERS

A novel 4-hydroxycoumarin biosynthetic pathway

(2009) Benye Liu et al.   PLANT MOLECULAR BIOLOGY

A structure-based mechanism for benzalacetone synthase from Rheum palmatum

(2009) H. Morita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystallization and preliminary X-ray diffraction studies of polyketide synthase-1 (PKS-1) fromCannabis sativa

(2008) Chiho Taguchi et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Crystallization and preliminary crystallographic analysis of a plant type III polyketide synthase that produces benzalacetone

(2008) Hiroyuki Morita et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Octaketide-producing type III polyketide synthase from Hypericum perforatum is expressed in dark glands accumulating hypericins

(2008) Katja Karppinen et al.   FEBS Journal

Prokaryotic expression, polyclonal antibody preparation of the stilbene synthase gene from grape berry and its different expression in fruit development and under heat acclimation

(2008) Wei Wang et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Molecular and biochemical characterization of benzalacetone synthase and chalcone synthase genes and their proteins from raspberry (Rubus idaeus L.)

(2007) Desen Zheng et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS