Cepharanthine: a review of the antiviral potential of a Japanese-approved alopecia drug in COVID-19

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

Identification of antiviral drug candidates against SARS-CoV-2 from FDA-approved drugs

(2020) Sangeun Jeon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Repurposing of clinically approved drugs for treatment of coronavirus disease 2019 in a 2019-novel coronavirus-related coronavirus model

(2020) Hua-Hao Fan et al.   CHINESE MEDICAL JOURNAL

Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19)

(2020) James M. Sanders et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Potential COVID-19 therapeutics from a rare disease: Weaponizing lipid dysregulation to combat viral infectivity

(2020) Stephen Sturley et al.   JOURNAL OF LIPID RESEARCH

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

(2020) Jun Lan et al.   NATURE

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir

(2020) Wanchao Yin et al.   SCIENCE

COVID-19, SARS and MERS: are they closely related?

(2020) N. Petrosillo et al.   CLINICAL MICROBIOLOGY AND INFECTION

SARS‐CoV‐2 and SARS‐CoV: Virtual screening of potential inhibitors targeting RNA‐dependent RNA polymerase activity (NSP12)

(2020) Zijing Ruan et al.   JOURNAL OF MEDICAL VIROLOGY

Cepharanthine: An update of its mode of action, pharmacological properties and medical applications

(2019) Christian Bailly   PHYTOMEDICINE

Natural Bis-Benzylisoquinoline Alkaloids-Tetrandrine, Fangchinoline, and Cepharanthine, Inhibit Human Coronavirus OC43 Infection of MRC-5 Human Lung Cells

(2019) Kim et al.   Biomolecules

Cepharanthine inhibits in vitro VSMC proliferation and migration and vascular inflammatory responses mediated by RAW264.7

(2016) Keshav Raj Paudel et al.   TOXICOLOGY IN VITRO

In vitro and in vivo combination of cepharanthine with anti-malarial drugs

(2014) Camille Desgrouas et al.   MALARIA JOURNAL

Therapeutic potential of the biscoclaurine alkaloid, cepharanthine, for a range of clinical conditions

(2014) Moshe Rogosnitzky et al.   Pharmacological Reports

Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells

(2014) Betty Yuen Kwan Law et al.   Scientific Reports

Cepharanthine Attenuates Lipopolysaccharide-Induced Mice Mastitis by Suppressing the NF-κB Signaling Pathway

(2013) Zhou Ershun et al.   INFLAMMATION

In vitro activity of cepharanthine hydrochloride against clinical wild-type and lamivudine-resistant hepatitis B virus isolates

(2012) Yu-Bing Zhou et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cepharanthine inhibits angiogenesis and tumorigenicity of human oral squamous cell carcinoma cells by suppressing expression of vascular endothelial growth factor and interleukin-8

(2009) Harada   INTERNATIONAL JOURNAL OF ONCOLOGY

Prevention and management of drug resistance for antihepatitis B treatment

(2009) Man-Fung Yuen et al.   LANCET INFECTIOUS DISEASES

Cepharanthine is a potent reversal agent for MRP7(ABCC10)-mediated multidrug resistance

(2008) Ying Zhou et al.   BIOCHEMICAL PHARMACOLOGY