Resveratrol analogues present effective antileishmanial activity against promastigotes and amastigotes from distinct Leishmania species by multitarget action in the parasites

Cell death pathways in pathogenic trypanosomatids: lessons of (over)kill

(2019) Rubem Figueiredo Sadok Menna-Barreto   Cell Death & Disease

Visceral Leishmaniasis

(2019) Johan van Griensven et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

A semi-synthetic neolignan derivative from dihydrodieugenol B selectively affects the bioenergetic system of Leishmania infantum and inhibits cell division

(2019) Maiara Amaral et al.   Scientific Reports

Tetrazolium salts and formazan products in Cell Biology: Viability assessment, fluorescence imaging, and labeling perspectives

(2018) Juan C. Stockert et al.   ACTA HISTOCHEMICA

Primary evidence of the mechanisms of action of HIV aspartyl peptidase inhibitors on Trypanosoma cruzi trypomastigote forms

(2018) Leandro S. Sangenito et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Resveratrol: An overview of its anti-cancer mechanisms

(2018) Mohamed Elshaer et al.   LIFE SCIENCES

Human leishmaniasis in Brazil: A general review

(2018) Laís Anversa et al.   Revista da Associacao Medica Brasileira

In vitro and in vivo anti-inflammatory properties of imine resveratrol analogues

(2018) Danielle Cristina Zimmermann-Franco et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Leishmaniasis

(2018) Sakib Burza et al.   LANCET

Intraspecies susceptibility of Leishmania (Viannia) braziliensis to antileishmanial drugs: Antimony resistance in human isolates from atypical lesions

(2018) Jeronimo N. Rugani et al.   BIOMEDICINE & PHARMACOTHERAPY

Antileishmanial activity of a 4-hydrazinoquinoline derivative: Induction of autophagy and apoptosis-related processes and effectiveness in experimental cutaneous leishmaniasis

(2018) Luciana Maria Ribeiro Antinarelli et al.   EXPERIMENTAL PARASITOLOGY

Mitochondrial disfunction and ROS production are essential for anti-Trypanosoma cruzi activity of β-lapachone-derived naphthoimidazoles

(2018) Ana Cristina S. Bombaça et al.   FREE RADICAL BIOLOGY AND MEDICINE

In vitro and in vivo antileishmanial activity of a fluoroquinoline derivate against Leishmania infantum and Leishmania amazonensis species

(2018) Grasiele S.V. Tavares et al.   ACTA TROPICA

Cutaneous Manifestations of Human and Murine Leishmaniasis

(2017) Breanna Scorza et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Repurposing as a strategy for the discovery of new anti-leishmanials: the-state-of-the-art

(2017) REBECCA L. CHARLTON et al.   PARASITOLOGY

Chemotherapy of leishmaniasis: present challenges

(2017) SILVIA R. B. ULIANA et al.   PARASITOLOGY

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Current Therapeutics, Their Problems and Thiol Metabolism as Potential Drug Targets in Leishmaniasis

(2016) Kuljit Singh et al.   CURRENT DRUG METABOLISM

Topical formulations of miltefosine for cutaneous leishmaniasis in a BALB/c mouse model

(2016) Katrien Van Bocxlaer et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Resveratrol and Cardiovascular Diseases

(2016) Dominique Bonnefont-Rousselot   Nutrients

Resveratrol Reverses Functional Chagas Heart Disease in Mice

(2016) Glaucia Vilar-Pereira et al.   PLoS Pathogens

Effects of a novel β–lapachone derivative on Trypanosoma cruzi : Parasite death involving apoptosis, autophagy and necrosis

(2016) Danielle Oliveira dos Anjos et al.   International Journal for Parasitology-Drugs and Drug Resistance

4-Aminoquinoline Derivatives as Potential Antileishmanial Agents

(2015) Luciana M. R. Antinarelli et al.   Chemical Biology & Drug Design

New World and Old World Leishmania Infections

(2015) Ines Kevric et al.   DERMATOLOGIC CLINICS

Cutaneous and mucocutaneous leishmaniasis

(2015) Marc Z. Handler et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

An Organ System Approach to Explore the Antioxidative, Anti-Inflammatory, and Cytoprotective Actions of Resveratrol

(2015) Ashim Malhotra et al.   Oxidative Medicine and Cellular Longevity

Apoptotic Cell Death Induced by Resveratrol Is Partially Mediated by the Autophagy Pathway in Human Ovarian Cancer Cells

(2015) Fangfang Lang et al.   PLoS One

Leishmanicidal Effect of Synthetic trans-Resveratrol Analogs

(2015) Carlos Luan Alves Passos et al.   PLoS One

Resveratrol Is Active against Leishmania amazonensis:In VitroEffect of Its Association with Amphotericin B

(2014) Christian Ferreira et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

(2014) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

The Effect of (-)-Epigallocatechin 3-O - Gallate In Vitro and In Vivo in Leishmania braziliensis: Involvement of Reactive Oxygen Species as a Mechanism of Action

(2014) Job D. F. Inacio et al.   PLoS Neglected Tropical Diseases

7-Chloro-4-quinolinyl Hydrazones: A Promising and Potent Class of Antileishmanial Compounds

(2013) Elaine S. Coimbra et al.   Chemical Biology & Drug Design

Further evidence of the trypanocidal action of eupomatenoid-5: Confirmation of involvement of reactive oxygen species and mitochondria owing to a reduction in trypanothione reductase activity

(2013) D. Lazarin-Bidóia et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive Oxygen Species Production by Quercetin Causes the Death of Leishmania amazonensis Intracellular Amastigotes

(2013) Fernanda Fonseca-Silva et al.   JOURNAL OF NATURAL PRODUCTS

Determinants for the Development of Visceral Leishmaniasis Disease

(2013) Laura-Isobel McCall et al.   PLoS Pathogens

TTAS a new stilbene derivative that induces apoptosis in Leishmania infantum

(2012) Manlio Tolomeo et al.   EXPERIMENTAL PARASITOLOGY

Autophagy in Trypanosomatids

(2012) Ana Brennand et al.   Cells

Redox-Active Antiparasitic Drugs

(2011) Chinmay Pal et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondria and Trypanosomatids: Targets and Drugs

(2011) Lianet Monzote Fidalgo et al.   PHARMACEUTICAL RESEARCH

Current diagnosis and treatment of cutaneous and mucocutaneous leishmaniasis

(2010) Hiro Goto et al.   Expert Review of Anti-Infective Therapy

Apoptotic markers in protozoan parasites

(2010) Antonio Jiménez-Ruiz et al.   Parasites & Vectors

Targeting essential pathways in trypanosomatids gives insights into protozoan mechanisms of cell death

(2010) Despina Smirlis et al.   Parasites & Vectors