Discovery of new therapeutic redox targets for cardioprotection against ischemia/reperfusion injury and heart failure
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Discovery of new therapeutic redox targets for cardioprotection against ischemia/reperfusion injury and heart failure
Authors
Keywords
Ischemia/reperfusion injury, Heart failure, Endothelial dysfunction, Mitochondrial dysfunction, Oxidative stress, Redox drugs
Journal
FREE RADICAL BIOLOGY AND MEDICINE
Volume 163, Issue -, Pages 325-343
Publisher
Elsevier BV
Online
2020-12-23
DOI
10.1016/j.freeradbiomed.2020.12.026
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Revisiting pharmacology of oxidative stress and endothelial dysfunction in cardiovascular disease: Evidence for redox-based therapies
- (2020) Andreas Daiber et al. FREE RADICAL BIOLOGY AND MEDICINE
- Chronic Empaglifozin treatment reduces myocardial infarct size in non-diabetic mice through STAT-3 mediated protection on microvascular endothelial cells and reduction of oxidative stress
- (2020) Panagiota Efstathia Nikolaou et al. ANTIOXIDANTS & REDOX SIGNALING
- Inhibition of xanthine oxidase in the acute phase of myocardial infarction prevents skeletal muscle abnormalities and exercise intolerance
- (2020) Hideo Nambu et al. CARDIOVASCULAR RESEARCH
- Therapeutic potential of phosphodiesterase inhibitors for endothelial dysfunction-related diseases
- (2020) Javier Blanco-Rivero et al. CURRENT PHARMACEUTICAL DESIGN
- Association between long-term prescription of febuxostat and the progression of heart failure with preserved ejection fraction in patients with hypertension and asymptomatic hyperuricemia
- (2020) Jian-an Pan et al. HEART AND VESSELS
- Regulation of Vascular Function and Inflammation via Cross Talk of Reactive Oxygen and Nitrogen Species from Mitochondria or NADPH Oxidase—Implications for Diabetes Progression
- (2020) Andreas Daiber et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The role of mitochondrial reactive oxygen species, NO and H 2 S in ischaemia/reperfusion injury and cardioprotection
- (2020) Ioanna Andreadou et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Endothelial dysfunction in patients with myocardial ischemia or infarction and nonobstructive coronary arteries
- (2020) Ersin Cagri Simsek et al. JOURNAL OF CLINICAL ULTRASOUND
- Protective effects of cardiac resynchronization therapy in a canine model with experimental heart failure by improving mitochondrial function: a mitochondrial proteomics study
- (2020) Xue Gong et al. JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
- SGLT2 inhibitors in patients with heart failure with reduced ejection fraction: a meta-analysis of the EMPEROR-Reduced and DAPA-HF trials
- (2020) Faiez Zannad et al. LANCET
- Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure
- (2020) Milton Packer et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Systematic Review of Medical Costs Associated with Heart Failure in the USA (2014–2020)
- (2020) Michael Urbich et al. PHARMACOECONOMICS
- On the Clinical Pharmacology of Reactive Oxygen Species
- (2020) Ana I. Casas et al. PHARMACOLOGICAL REVIEWS
- Oxidative Stress in Cardiovascular Diseases
- (2020) Emilie Dubois-Deruy et al. Antioxidants
- New Therapeutic Implications of Endothelial Nitric Oxide Synthase (eNOS) Function/Dysfunction in Cardiovascular Disease
- (2019) Andreas Daiber et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The effects of coenzyme Q10 supplementation on biomarkers of inflammation and oxidative stress in among coronary artery disease: a systematic review and meta-analysis of randomized controlled trials
- (2019) Mohammad Vahid Jorat et al. INFLAMMOPHARMACOLOGY
- Medical Therapy for Heart Failure Caused by Ischemic Heart Disease
- (2019) Islam Y. Elgendy et al. CIRCULATION RESEARCH
- Reactive species-induced microvascular dysfunction in ischemia/reperfusion
- (2019) Hong Yu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Effect of resveratrol on metabolic syndrome components: A systematic review and meta-analysis
- (2019) Sedigheh Asgary et al. REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
- Blood Pressure–Lowering by the Antioxidant Resveratrol Is Counterintuitively Mediated by Oxidation of cGMP-Dependent Protein Kinase
- (2019) Oleksandra Prysyazhna et al. CIRCULATION
- Exercise-based cardiac rehabilitation in patients with reduced left ventricular ejection fraction: The Cardiac Rehabilitation Outcome Study in Heart Failure (CROS-HF): A systematic review and meta-analysis
- (2019) Birna Bjarnason-Wehrens et al. European Journal of Preventive Cardiology
- Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction
- (2019) John J.V. McMurray et al. NEW ENGLAND JOURNAL OF MEDICINE
- α-Tocopherol preserves cardiac function by reducing oxidative stress and inflammation in ischemia/reperfusion injury
- (2019) Maria Wallert et al. Redox Biology
- NADPH oxidases and oxidase crosstalk in cardiovascular diseases: novel therapeutic targets
- (2019) Yixuan Zhang et al. Nature Reviews Cardiology
- Environmental Stressors and Their Impact on Health and Disease with Focus on Oxidative Stress
- (2018) Thomas Münzel et al. ANTIOXIDANTS & REDOX SIGNALING
- Xanthine oxidase inhibitors for prevention of cardiovascular events: a systematic review and meta-analysis of randomized controlled trials
- (2018) Markus Bredemeier et al. BMC Cardiovascular Disorders
- Effects of the concomitant administration of xanthine oxidase inhibitors with zofenopril or other ACE-inhibitors in post-myocardial infarction patients: a meta-analysis of individual data of four randomized, double-blind, prospective studies
- (2018) Claudio Borghi et al. BMC Cardiovascular Disorders
- Assessment of Cardiovascular Risk in Older Patients with Gout Initiating Febuxostat versus Allopurinol: A Population-Based Cohort Study
- (2018) MaryAnn Zhang et al. CIRCULATION
- Meta-Analysis of Cell Therapy Studies in Heart Failure and Acute Myocardial Infarction
- (2018) Mariann Gyöngyösi et al. CIRCULATION RESEARCH
- The effects of xanthine oxidase inhibitor in patients with chronic heart failure complicated with hyperuricemia: a prospective randomized controlled clinical trial of topiroxostat vs allopurinol—study protocol
- (2018) Masashi Sakuma et al. Clinical and Experimental Nephrology
- Beneficial Effects of N-acetylcysteine and N-mercaptopropionylglycine on Ischemia Reperfusion Injury in the Heart
- (2018) Monika Bartekova et al. CURRENT MEDICINAL CHEMISTRY
- The Role of Redox Dysregulation in the Inflammatory Response to Acute Myocardial Ischaemia-reperfusion Injury - Adding Fuel to the Fire
- (2018) Sauri Hernandez-Resendiz et al. CURRENT MEDICINAL CHEMISTRY
- ROS and redox signaling in myocardial ischemia-reperfusion injury and cardioprotection
- (2018) Susana Cadenas FREE RADICAL BIOLOGY AND MEDICINE
- Influence of exercise on oxidative stress in patients with heart failure
- (2018) Sabrina Weiss Sties et al. HEART FAILURE REVIEWS
- Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach
- (2018) Antonio Cuadrado et al. PHARMACOLOGICAL REVIEWS
- Effects of Ramadan fasting on the symptoms of chronic heart failure
- (2018) Rami Abazid et al. SAUDI MEDICAL JOURNAL
- Nitroglycerine limits infarct size through S-nitrosation of cyclophilin D: a novel mechanism for an old drug
- (2018) Sofia-Iris Bibli et al. CARDIOVASCULAR RESEARCH
- Effects of SGLT2 inhibitors on systemic and tissue low-grade inflammation: the potential contribution to diabetes complications and cardiovascular disease
- (2018) Fabrice Bonnet et al. DIABETES & METABOLISM
- Comparison of New Glucose-Lowering Drugs on Risk of Heart Failure in Type 2 Diabetes
- (2018) Caroline K. Kramer et al. JACC-Heart Failure
- Empagliflozin, an SGLT2 inhibitor, reduced the mortality rate after acute myocardial infarction with modification of cardiac metabolomes and anti-oxidants in diabetic rats.
- (2018) Hiroto Oshima et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- The SGLT2 Inhibitor Luseogliflozin Rapidly Normalizes Aortic mRNA Levels of Inflammation-Related but Not Lipid-Metabolism-Related Genes and Suppresses Atherosclerosis in Diabetic ApoE KO Mice
- (2017) Yusuke Nakatsu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Effect of dipeptidyl peptidase-4 inhibitors on circulating tumor necrosis factor-α concentrations: A systematic review and meta-analysis of controlled trials
- (2017) Stephen L. Atkin et al. JOURNAL OF DIABETES AND ITS COMPLICATIONS
- Impact of Oxidative Stress on the Heart and Vasculature
- (2017) Thomas Münzel et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- 8-Hydroxy-2-deoxyguanosine levels and heart failure: A systematic review and meta-analysis of the literature
- (2017) A. Di Minno et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
- Loss of Nrf2 promotes rapid progression to heart failure following myocardial infarction
- (2017) Joshua Strom et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- The Effect of Polyphenol-Rich Interventions on Cardiovascular Risk Factors in Haemodialysis: A Systematic Review and Meta-Analysis
- (2017) Wolfgang Marx et al. Nutrients
- Empagliflozin Limits Myocardial Infarction in Vivo and Cell Death in Vitro: Role of STAT3, Mitochondria, and Redox Aspects
- (2017) Ioanna Andreadou et al. Frontiers in Physiology
- European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)
- (2017) Javier Egea et al. Redox Biology
- Taking up the cudgels for the traditional reactive oxygen and nitrogen species detection assays and their use in the cardiovascular system
- (2017) Andreas Daiber et al. Redox Biology
- Mitochondrial-targeted catalase is good for the old mouse proteome, but not for the young: ‘reverse’ antagonistic pleiotropy?
- (2016) Nathan Basisty et al. AGING CELL
- 8-Hydroxy-2-Deoxyguanosine Levels and Cardiovascular Disease: A Systematic Review and Meta-Analysis of the Literature
- (2016) Alessandro Di Minno et al. ANTIOXIDANTS & REDOX SIGNALING
- Crosstalk of mitochondria with NADPH oxidase via reactive oxygen and nitrogen species signalling and its role for vascular function
- (2016) Andreas Daiber et al. BRITISH JOURNAL OF PHARMACOLOGY
- Targeting vascular (endothelial) dysfunction
- (2016) Andreas Daiber et al. BRITISH JOURNAL OF PHARMACOLOGY
- A Unifying Mechanism for Mitochondrial Superoxide Production during Ischemia-Reperfusion Injury
- (2016) Edward T. Chouchani et al. Cell Metabolism
- Mitochondrial Function, Biology, and Role in Disease
- (2016) Elizabeth Murphy et al. CIRCULATION RESEARCH
- The beneficial effects of empagliflozin, an SGLT2 inhibitor, on atherosclerosis in ApoE −/− mice fed a western diet
- (2016) Ji Hye Han et al. DIABETOLOGIA
- Pharmacological targeting of mitochondrial reactive oxygen species counteracts diaphragm weakness in chronic heart failure
- (2016) Orlando Laitano et al. JOURNAL OF APPLIED PHYSIOLOGY
- Effects of urate-lowering agents on arrhythmia vulnerability in post-infarcted rat hearts
- (2016) Tsung-Ming Lee et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Ischaemic conditioning and reperfusion injury
- (2016) Derek J. Hausenloy et al. Nature Reviews Cardiology
- Preconditioning is hormesis part I: Documentation, dose-response features and mechanistic foundations
- (2016) Edward J. Calabrese PHARMACOLOGICAL RESEARCH
- Real-Time Fluorescence Measurements of ROS and [Ca2+] in Ischemic / Reperfused Rat Hearts: Detectable Increases Occur only after Mitochondrial Pore Opening and Are Attenuated by Ischemic Preconditioning
- (2016) Tatyana Andrienko et al. PLoS One
- Health effects of intermittent fasting: hormesis or harm? A systematic review
- (2015) Benjamin D Horne et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Does Mediterranean Diet Reduce Cardiovascular Events and Oxidative Stress in Atrial Fibrillation?
- (2015) Daniele Pastori et al. ANTIOXIDANTS & REDOX SIGNALING
- Pharmacology and Clinical Drug Candidates in Redox Medicine
- (2015) V. Thao-Vi Dao et al. ANTIOXIDANTS & REDOX SIGNALING
- Antioxidants in Translational Medicine
- (2015) Harald H.H.W. Schmidt et al. ANTIOXIDANTS & REDOX SIGNALING
- Reactive Oxygen-Related Diseases: Therapeutic Targets and Emerging Clinical Indications
- (2015) Ana I. Casas et al. ANTIOXIDANTS & REDOX SIGNALING
- Clinical Relevance of Biomarkers of Oxidative Stress
- (2015) Jeroen Frijhoff et al. ANTIOXIDANTS & REDOX SIGNALING
- Evidence for the free radical/oxidative stress theory of ageing from the CHANCES consortium: a meta-analysis of individual participant data
- (2015) Ben Schöttker et al. BMC Medicine
- Redox signalling and cardioprotection: translatability and mechanism
- (2015) P Pagliaro et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cardioprotection by H2S engages a cGMP-dependent protein kinase G/phospholamban pathway
- (2015) Sofia-Iris Bibli et al. CARDIOVASCULAR RESEARCH
- Antioxidant and anti-inflammatory effects of curcuminoid-piperine combination in subjects with metabolic syndrome: A randomized controlled trial and an updated meta-analysis
- (2015) Yunes Panahi et al. CLINICAL NUTRITION
- Modulation of Mitochondrial Permeability Transition in Ischemia-Reperfusion Injury of the Heart. Advantages and Limitations
- (2015) Fabio Lisa et al. CURRENT MEDICINAL CHEMISTRY
- EMBRACE STEMI study: a Phase 2a trial to evaluate the safety, tolerability, and efficacy of intravenous MTP-131 on reperfusion injury in patients undergoing primary percutaneous coronary intervention
- (2015) C. Michael Gibson et al. EUROPEAN HEART JOURNAL
- The NADPH oxidase Nox4 has anti-atherosclerotic functions
- (2015) Christoph Schürmann et al. EUROPEAN HEART JOURNAL
- Pathophysiological role of oxidative stress in systolic and diastolic heart failure and its therapeutic implications
- (2015) Thomas Münzel et al. EUROPEAN HEART JOURNAL
- NOX4-dependent Hydrogen peroxide promotes shear stress-induced SHP2 sulfenylation and eNOS activation
- (2015) Francisco J. Sánchez-Gómez et al. FREE RADICAL BIOLOGY AND MEDICINE
- Aldehydic load and aldehyde dehydrogenase 2 profile during the progression of post-myocardial infarction cardiomyopathy: Benefits of Alda-1
- (2015) Katia M.S. Gomes et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Exploiting the Pleiotropic Antioxidant Effects of Established Drugs in Cardiovascular Disease
- (2015) Sebastian Steven et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Attenuation of Ca2+ homeostasis, oxidative stress, and mitochondrial dysfunctions in diabetic rat heart: insulin therapy or aerobic exercise?
- (2015) Márcia F. da Silva et al. JOURNAL OF APPLIED PHYSIOLOGY
- Febuxostat pretreatment attenuates myocardial ischemia/reperfusion injury via mitochondrial apoptosis
- (2015) Shulin Wang et al. Journal of Translational Medicine
- Bendavia restores mitochondrial energy metabolism gene expression and suppresses cardiac fibrosis in the border zone of the infarcted heart
- (2015) Jianru Shi et al. LIFE SCIENCES
- Detrimental effects of chemotherapeutics and other drugs on the endothelium: A call for endothelial toxicity profiling
- (2015) Tomasz Wojcik et al. Pharmacological Reports
- Serum NOX2 and urinary isoprostanes predict vascular events in patients with atrial fibrillation
- (2015) Roberto Carnevale et al. THROMBOSIS AND HAEMOSTASIS
- Oxidative stress: a concept in redox biology and medicine
- (2015) Helmut Sies Redox Biology
- Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair
- (2015) Yuliya Mikhed et al. Redox Biology
- Genetic disorders coupled to ROS deficiency
- (2015) Sharon O’Neill et al. Redox Biology
- Reperfusion injury and reactive oxygen species: The evolution of a concept
- (2015) D. Neil Granger et al. Redox Biology
- Reactive Oxygen Species Regulate Hematopoietic Stem Cell Self-Renewal, Migration and Development, As Well As Their Bone Marrow Microenvironment
- (2014) Aya Ludin et al. ANTIOXIDANTS & REDOX SIGNALING
- The role of gasotransmitters NO, H2S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning
- (2014) Ioanna Andreadou et al. BRITISH JOURNAL OF PHARMACOLOGY
- Riociguat: A Novel Therapeutic Option for Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension
- (2014) Lisa M. Mielniczuk et al. CANADIAN JOURNAL OF CARDIOLOGY
- Reduced Oxidative Stress in STEMI Patients Treated by Primary Percutaneous Coronary Intervention and with Antioxidant Therapy: A Systematic Review
- (2014) Sarah Ekeløf et al. CARDIOVASCULAR DRUGS AND THERAPY
- Inhibiting Mitochondrial Na + /Ca 2+ Exchange Prevents Sudden Death in a Guinea Pig Model of Heart Failure
- (2014) Ting Liu et al. CIRCULATION RESEARCH
- Effect of intravenous TRO40303 as an adjunct to primary percutaneous coronary intervention for acute ST-elevation myocardial infarction: MITOCARE study results
- (2014) D. Atar et al. EUROPEAN HEART JOURNAL
- Redox regulation of antioxidants, autophagy, and the response to stress: Implications for electrophile therapeutics
- (2014) Anna-Liisa Levonen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Bendavia, a Mitochondria-targeting Peptide, Improves Postinfarction Cardiac Function, Prevents Adverse Left Ventricular Remodeling, and Restores Mitochondria-related Gene Expression in Rats
- (2014) Wangde Dai et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Monoamine oxidases as sources of oxidants in the heart
- (2014) Nina Kaludercic et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Mitochondria-targeted antioxidant (MitoQ) ameliorates age-related arterial endothelial dysfunction in mice
- (2014) Rachel A. Gioscia-Ryan et al. JOURNAL OF PHYSIOLOGY-LONDON
- Mediterranean Diet and Cardiovascular Health: Teachings of the PREDIMED Study
- (2014) Emilio Ros et al. Advances in Nutrition
- Oxidative Damage in Clinical Ischemia/Reperfusion Injury: A Reappraisal
- (2013) Dorottya K. de Vries et al. ANTIOXIDANTS & REDOX SIGNALING
- Molecular Mechanisms of the Crosstalk Between Mitochondria and NADPH Oxidase Through Reactive Oxygen Species—Studies in White Blood Cells and in Animal Models
- (2013) Swenja Kröller-Schön et al. ANTIOXIDANTS & REDOX SIGNALING
- Redox Modulation of Endothelial Nitric Oxide Synthase by Glutaredoxin-1 through Reversible Oxidative Post-Translational Modification
- (2013) Chun-An Chen et al. BIOCHEMISTRY
- Delivery of Nox2-NADPH oxidase siRNA with polyketal nanoparticles for improving cardiac function following myocardial infarction
- (2013) Inthirai Somasuntharam et al. BIOMATERIALS
- Broad Suppression of NADPH Oxidase Activity Exacerbates Ischemia/Reperfusion Injury Through Inadvertent Downregulation of Hypoxia-inducible Factor-1α and Upregulation of Peroxisome Proliferator–activated Receptor-α
- (2013) Shouji Matsushima et al. CIRCULATION RESEARCH
- Cardioprotection Techniques: Preconditioning, Postconditioning and Remote Con-ditioning (Basic Science)
- (2013) Derek Hausenloy CURRENT PHARMACEUTICAL DESIGN
- More answers to the still unresolved question of nitrate tolerance
- (2013) Thomas Münzel et al. EUROPEAN HEART JOURNAL
- Efficacy of the long-acting nitro vasodilator pentaerithrityl tetranitrate in patients with chronic stable angina pectoris receiving anti-anginal background therapy with beta-blockers: a 12-week, randomized, double-blind, placebo-controlled trial
- (2013) Thomas Münzel et al. EUROPEAN HEART JOURNAL
- Myocardial reperfusion injury: looking beyond primary PCI
- (2013) Georg M. Fröhlich et al. EUROPEAN HEART JOURNAL
- How do nutritional antioxidants really work: Nucleophilic tone and para-hormesis versus free radical scavenging in vivo
- (2013) Henry J. Forman et al. FREE RADICAL BIOLOGY AND MEDICINE
- Körperliches Training bei Herzinsuffizienz
- (2013) F. Edelmann et al. HERZ
- The Effect of Statins on Circulating Endothelial Progenitor Cells in Humans
- (2013) Benjamin Hibbert et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Myocardial ischemia-reperfusion injury: a neglected therapeutic target
- (2013) Derek J. Hausenloy et al. JOURNAL OF CLINICAL INVESTIGATION
- Macitentan and Morbidity and Mortality in Pulmonary Arterial Hypertension
- (2013) Tomás Pulido et al. NEW ENGLAND JOURNAL OF MEDICINE
- Phenotyping of Left and Right Ventricular Function in Mouse Models of Compensated Hypertrophy and Heart Failure with Cardiac MRI
- (2013) Bastiaan J. van Nierop et al. PLoS One
- Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators
- (2013) B. P. Hubbard et al. SCIENCE
- ROS‐Mediated PARP Activity Undermines Mitochondrial Function After Permeability Transition Pore Opening During Myocardial Ischemia–Reperfusion
- (2013) Jacqueline M. Schriewer et al. Journal of the American Heart Association
- Usefulness of Cardiac Biomarker Score for Risk Stratification in Stable Patients Undergoing Elective Cardiac Evaluation Across Glycemic Status
- (2012) W.H. Wilson Tang et al. AMERICAN JOURNAL OF CARDIOLOGY
- NADPH Oxidases in Heart Failure: Poachers or Gamekeepers?
- (2012) Min Zhang et al. ANTIOXIDANTS & REDOX SIGNALING
- Mitochondrial Redox Signaling: Interaction of Mitochondrial Reactive Oxygen Species with Other Sources of Oxidative Stress
- (2012) Eberhard Schulz et al. ANTIOXIDANTS & REDOX SIGNALING
- Emerging beneficial roles of sirtuins in heart failure
- (2012) Masaya Tanno et al. BASIC RESEARCH IN CARDIOLOGY
- Postchallenge responses of nitrotyrosine and TNF-alpha during 75-g oral glucose tolerance test are associated with the presence of coronary artery diseases in patients with prediabetes
- (2012) Chih-Sheng Chu et al. Cardiovascular Diabetology
- The NOX toolbox: validating the role of NADPH oxidases in physiology and disease
- (2012) Sebastian Altenhöfer et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase
- (2012) Katrin Schröder et al. CIRCULATION RESEARCH
- Regulation of the Inflammatory Response in Cardiac Repair
- (2012) Nikolaos G. Frangogiannis CIRCULATION RESEARCH
- Free radical biology of the cardiovascular system
- (2012) Alex F. Chen et al. CLINICAL SCIENCE
- Chronic therapy with isosorbide-5-mononitrate causes endothelial dysfunction, oxidative stress, and a marked increase in vascular endothelin-1 expression
- (2012) Matthias Oelze et al. EUROPEAN HEART JOURNAL
- Oxidative regulation of the Na+–K+ pump in the cardiovascular system
- (2012) Gemma A. Figtree et al. FREE RADICAL BIOLOGY AND MEDICINE
- Cardioprotective Effects of Telmisartan against Heart Failure in Rats Induced By Experimental Autoimmune Myocarditis through the Modulation of Angiotensin-Converting Enzyme-2/Angiotensin 1-7/Mas Receptor Axis
- (2012) Vijayakumar Sukumaran et al. International Journal of Biological Sciences
- The novel DPP-4 inhibitors linagliptin and BI 14361 reduce infarct size after myocardial ischemia/reperfusion in rats
- (2012) Berthold Hocher et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- NADPH oxidases as a source of oxidative stress and molecular target in ischemia/reperfusion injury
- (2012) Pamela W. M. Kleikers et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- A Dipeptidyl Peptidase-4 Inhibitor, Des-Fluoro-Sitagliptin, Improves Endothelial Function and Reduces Atherosclerotic Lesion Formation in Apolipoprotein E–Deficient Mice
- (2012) Junichi Matsubara et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
- (2012) Rafael Lozano et al. LANCET
- Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors
- (2012) Elisabet Wahlberg et al. NATURE BIOTECHNOLOGY
- Increased Poly(ADP-Ribosyl)ation in Peripheral Leukocytes and the Reperfused Myocardium Tissue of Rats With Ischemia/Reperfusion Injury
- (2012) Li-qun Zhang et al. SHOCK
- Redox regulation of cell migration and adhesion
- (2012) Thomas Ryan Hurd et al. TRENDS IN CELL BIOLOGY
- Reduction of Ischemia/Reperfusion Injury With Bendavia, a Mitochondria‐Targeting Cytoprotective Peptide
- (2012) Robert A. Kloner et al. Journal of the American Heart Association
- S-Glutathionylation Reshapes Our Understanding of Endothelial Nitric Oxide Synthase Uncoupling and Nitric Oxide/Reactive Oxygen Species-Mediated Signaling
- (2011) Jay L. Zweier et al. ANTIOXIDANTS & REDOX SIGNALING
- Mitochondria-Targeted Small Molecule Therapeutics and Probes
- (2011) Robin A.J. Smith et al. ANTIOXIDANTS & REDOX SIGNALING
- How to manage hypertension in pregnancy effectively
- (2011) Laura A. Magee et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Tetrahydrobiopterin depletion and NOS2 uncoupling contribute to heart failure-induced alterations in atrial electrophysiology
- (2011) Yoshinori Nishijima et al. CARDIOVASCULAR RESEARCH
- Slow calcium waves and redox changes precede mitochondrial permeability transition pore opening in the intact heart during hypoxia and reoxygenation
- (2011) Sean M. Davidson et al. CARDIOVASCULAR RESEARCH
- Xanthine Oxidase Inhibition For The Treatment Of Cardiovascular Disease: A Systematic Review and Meta-Analysis
- (2011) Peter Higgins et al. Cardiovascular Therapeutics
- Nitrate Therapy
- (2011) Thomas Münzel et al. CIRCULATION
- Long-Term Dipeptidyl-Peptidase 4 Inhibition Reduces Atherosclerosis and Inflammation via Effects on Monocyte Recruitment and Chemotaxis
- (2011) Zubair Shah et al. CIRCULATION
- Mitochondrial Oxidative Stress Mediates Angiotensin II–Induced Cardiac Hypertrophy and Gαq Overexpression–Induced Heart Failure
- (2011) Dao-Fu Dai et al. CIRCULATION RESEARCH
- Risk Prediction with Serial Myeloperoxidase Monitoring in Patients with Acute Chest Pain
- (2011) S. J. Nicholls et al. CLINICAL CHEMISTRY
- Vascular Dysfunction in Experimental Diabetes Is Improved by Pentaerithrityl Tetranitrate but Not Isosorbide-5-Mononitrate Therapy
- (2011) S. Schuhmacher et al. DIABETES
- Endothelial function assessment: flow-mediated dilation and constriction provide different and complementary information on the presence of coronary artery disease
- (2011) Tommaso Gori et al. EUROPEAN HEART JOURNAL
- NADPH oxidase-dependent oxidative stress in the failing heart: From pathogenic roles to therapeutic approach
- (2011) Yanti Octavia et al. FREE RADICAL BIOLOGY AND MEDICINE
- Bi-modal dose-dependent cardiac response to tetrahydrobiopterin in pressure-overload induced hypertrophy and heart failure
- (2011) An L. Moens et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Targeting Mitochondrial Oxidative Stress in Heart Failure
- (2011) Christoph Maack et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Unknown
- (2011) Jiali Wang et al. MOLECULAR MEDICINE
- Ischemia and reperfusion—from mechanism to translation
- (2011) Holger K Eltzschig et al. NATURE MEDICINE
- Innate immune signaling in cardiac ischemia
- (2011) Fatih Arslan et al. Nature Reviews Cardiology
- Mitochondrial oxidant stress triggers cell death in simulated ischemia–reperfusion
- (2010) Gabriel Loor et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Silencing Nox4 in the Paraventricular Nucleus Improves Myocardial Infarction–Induced Cardiac Dysfunction by Attenuating Sympathoexcitation and Periinfarct Apoptosis
- (2010) David W. Infanger et al. CIRCULATION RESEARCH
- Is oxidative stress a therapeutic target in cardiovascular disease?
- (2010) Thomas Münzel et al. EUROPEAN HEART JOURNAL
- Reactive oxygen species, cellular redox systems, and apoptosis
- (2010) Magdalena L. Circu et al. FREE RADICAL BIOLOGY AND MEDICINE
- TRO40303, a New Cardioprotective Compound, Inhibits Mitochondrial Permeability Transition
- (2010) S. Schaller et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- S-glutathionylation uncouples eNOS and regulates its cellular and vascular function
- (2010) Chun-An Chen et al. NATURE
- NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis
- (2010) M. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Usefulness of Elevations in Serum Choline and Free F2-Isoprostane to Predict 30-Day Cardiovascular Outcomes in Patients With Acute Coronary Syndrome
- (2009) Rebecca M. LeLeiko et al. AMERICAN JOURNAL OF CARDIOLOGY
- Novel Role of NADPH Oxidase in Angiogenesis and Stem/Progenitor Cell Function
- (2009) Masuko Ushio-Fukai et al. ANTIOXIDANTS & REDOX SIGNALING
- The eNOS enhancer AVE 9488: a novel cardioprotectant against ischemia reperfusion injury
- (2009) S. Frantz et al. BASIC RESEARCH IN CARDIOLOGY
- Enhancement of the endothelial NO synthase attenuates experimental diastolic heart failure
- (2009) Dirk Westermann et al. BASIC RESEARCH IN CARDIOLOGY
- Role of guanylate cyclase modulators in decompensated heart failure
- (2009) Veselin Mitrovic et al. HEART FAILURE REVIEWS
- Exenatide Reduces Infarct Size and Improves Cardiac Function in a Porcine Model of Ischemia and Reperfusion Injury
- (2009) Leo Timmers et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Antioxidants prevent health-promoting effects of physical exercise in humans
- (2009) M. Ristow et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular Mechanisms and Clinical Implications of Reversible Protein S-Glutathionylation
- (2008) John J. Mieyal et al. ANTIOXIDANTS & REDOX SIGNALING
- Are polyphenols antioxidants or pro-oxidants? What do we learn from cell culture and in vivo studies?
- (2008) Barry Halliwell ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Improvement in Left Ventricular Remodeling by the Endothelial Nitric Oxide Synthase Enhancer AVE9488 After Experimental Myocardial Infarction
- (2008) Daniela Fraccarollo et al. CIRCULATION
- Elevated levels of myeloperoxidase, white blood cell count and 3-chlorotyrosine in Taiwanese patients with acute myocardial infarction
- (2008) Mei-Ling Cheng et al. CLINICAL BIOCHEMISTRY
- Involvement of Nox2 NADPH Oxidase in Adverse Cardiac Remodeling After Myocardial Infarction
- (2008) Yee H. Looi et al. HYPERTENSION
- Xanthine Oxidase Inhibition With Febuxostat Attenuates Systolic Overload-Induced Left Ventricular Hypertrophy and Dysfunction in Mice
- (2008) Xin Xu et al. JOURNAL OF CARDIAC FAILURE
- Prevention of ischemia/reperfusion-induced cardiac apoptosis and injury by melatonin is independent of glutathione peroxdiase 1
- (2008) Zhongyi Chen et al. JOURNAL OF PINEAL RESEARCH
- Biomarkers in Heart Failure
- (2008) Eugene Braunwald NEW ENGLAND JOURNAL OF MEDICINE
- Effect of Cyclosporine on Reperfusion Injury in Acute Myocardial Infarction
- (2008) Christophe Piot et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mechanisms Underlying Acute Protection From Cardiac Ischemia-Reperfusion Injury
- (2008) Elizabeth Murphy et al. PHYSIOLOGICAL REVIEWS
- Circulating white blood cells and platelets amplify oxidative stress in heart failure
- (2008) Alexander JJ IJsselmuiden et al. Nature clinical practice. Cardiovascular medicine
- Regulation of Proliferation of Skeletal Muscle Precursor Cells By NADPH Oxidase
- (2007) Mahroo Mofarrahi et al. ANTIOXIDANTS & REDOX SIGNALING
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started