Crosstalk of mitochondria with NADPH oxidase via reactive oxygen and nitrogen species signalling and its role for vascular function

NOX4 in Mitochondria: Yeast Two-Hybrid-Based Interaction with Complex I Without Relevance for Basal Reactive Oxygen Species?

(2015) Christine Hirschhäuser et al.   ANTIOXIDANTS & REDOX SIGNALING

Antioxidants in Translational Medicine

(2015) Harald H.H.W. Schmidt et al.   ANTIOXIDANTS & REDOX SIGNALING

Distinct mPTP activation mechanisms in ischaemia–reperfusion: contributions of Ca2+, ROS, pH, and inorganic polyphosphate

(2015) Lea K. Seidlmayer et al.   CARDIOVASCULAR RESEARCH

The mitochondrial permeability transition pore: Molecular nature and role as a target in cardioprotection

(2015) Paolo Bernardi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Manganese superoxide dismutase in carcinogenesis: friend or foe?

(2014) Anja Konzack et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The role of gasotransmitters NO, H2S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning

(2014) Ioanna Andreadou et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cardiac NO signalling in the metabolic syndrome

(2014) O Pechánová et al.   BRITISH JOURNAL OF PHARMACOLOGY

Uncoupling protein 3 mediates H2O2 preconditioning-afforded cardioprotection through the inhibition of MPTP opening

(2014) Yixiong Chen et al.   CARDIOVASCULAR RESEARCH

eNOS Uncoupling in Cardiovascular Diseases - the Role of Oxidative Stress and Inflammation

(2014) Susanne Karbach et al.   CURRENT PHARMACEUTICAL DESIGN

Role of Nitric Oxide Synthase Uncoupling at Rostral Ventrolateral Medulla in Redox-Sensitive Hypertension Associated With Metabolic Syndrome

(2014) Kay L.H. Wu et al.   HYPERTENSION

Mitochondrial reactive oxygen species production and elimination

(2014) Alexander Nickel et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Monoamine oxidases as sources of oxidants in the heart

(2014) Nina Kaludercic et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Nitrate tolerance as a model of vascular dysfunction: Roles for mitochondrial aldehyde dehydrogenase and mitochondrial oxidative stress

(2014) Andreas Daiber et al.   Pharmacological Reports

Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release

(2014) Dmitry B. Zorov et al.   PHYSIOLOGICAL REVIEWS

Regulation of superoxide flashes by transient and steady mitochondrial calcium elevations

(2014) ChongShu Jian et al.   Science China-Life Sciences

Nox2 as a potential target of mitochondrial superoxide and its role in endothelial oxidative stress

(2013) Rafal R. Nazarewicz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cholesterol-enriched diet inhibits cardioprotection by ATP-sensitive K+ channel activators cromakalim and diazoxide

(2013) Csaba Csonka et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Redox Control of Inflammation in Macrophages

(2013) Bernhard Brüne et al.   ANTIOXIDANTS & REDOX SIGNALING

Nox2-Induced Production of Mitochondrial Superoxide in Angiotensin II-Mediated Endothelial Oxidative Stress and Hypertension

(2013) Sergey I. Dikalov et al.   ANTIOXIDANTS & REDOX SIGNALING

Relationship Between Redox Status and Cell Fate in Immunity and Autoimmunity

(2013) Elena Ortona et al.   ANTIOXIDANTS & REDOX SIGNALING

Molecular Mechanisms of the Crosstalk Between Mitochondria and NADPH Oxidase Through Reactive Oxygen Species—Studies in White Blood Cells and in Animal Models

(2013) Swenja Kröller-Schön et al.   ANTIOXIDANTS & REDOX SIGNALING

Monoamine Oxidase B Prompts Mitochondrial and Cardiac Dysfunction in Pressure Overloaded Hearts

(2013) Nina Kaludercic et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Modulation of HMGB1-Related Signaling

(2013) Christina Janko et al.   ANTIOXIDANTS & REDOX SIGNALING

Delivery of Nox2-NADPH oxidase siRNA with polyketal nanoparticles for improving cardiac function following myocardial infarction

(2013) Inthirai Somasuntharam et al.   BIOMATERIALS

Role of the c subunit of the FOATP synthase in mitochondrial permeability transition

(2013) Massimo Bonora et al.   CELL CYCLE

New roles for old pathways? A circuitous relationship between reactive oxygen species and cyclo-oxygenase in hypertension

(2013) Raquel Hernanz et al.   CLINICAL SCIENCE

The STAT3 Inhibitor Stattic Impairs Cardiomyocyte Mitochondrial Function Through Increased Reactive Oxygen Species Formation

(2013) Kerstin Boengler et al.   CURRENT PHARMACEUTICAL DESIGN

Structural determinants of the hydrogen peroxide permeability of aquaporins

(2013) Abdulnasser Almasalmeh et al.   FEBS Journal

Oxidative stress and vascular inflammation in aging

(2013) Mariam El Assar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Redox regulation of SIRT1 in inflammation and cellular senescence

(2013) Jae-woong Hwang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Monoamine Oxidases Are Mediators of Endothelial Dysfunction in the Mouse Aorta

(2013) Adrian Sturza et al.   HYPERTENSION

Glutathione Peroxidase-1 Deficiency Potentiates Dysregulatory Modifications of Endothelial Nitric Oxide Synthase and Vascular Dysfunction in Aging

(2013) Matthias Oelze et al.   HYPERTENSION

Nox4 NADPH Oxidase Mediates Peroxynitrite-dependent Uncoupling of Endothelial Nitric-oxide Synthase and Fibronectin Expression in Response to Angiotensin II

(2013) Doug-Yoon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-25-dependent up-regulation of NADPH oxidase 4 (NOX4) mediates hypercholesterolemia-induced oxidative/nitrative stress and subsequent dysfunction in the heart

(2013) Zoltán V. Varga et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Permeability transition pore-mediated mitochondrial superoxide flashes mediate an early inhibitory effect of amyloid beta1−42 on neural progenitor cell proliferation

(2013) Yan Hou et al.   NEUROBIOLOGY OF AGING

A role for mitochondrial oxidants in stress-induced premature senescence of human vascular smooth muscle cells

(2013) Yogita Mistry et al.   Redox Biology

Mitochondrial reactive oxygen species and calcium uptake regulate activation of phagocytic NADPH oxidase

(2012) Sergey I. Dikalov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Autocatalytic Nitration of Prostaglandin Endoperoxide Synthase-2 by Nitrite Inhibits Prostanoid Formation in Rat Alveolar Macrophages

(2012) Stefan Schildknecht et al.   ANTIOXIDANTS & REDOX SIGNALING

Angiotensin II-Induced Production of Mitochondrial Reactive Oxygen Species: Potential Mechanisms and Relevance for Cardiovascular Disease

(2012) Sergey I. Dikalov et al.   ANTIOXIDANTS & REDOX SIGNALING

Sensing Hypoxia by Mitochondria: A Unifying Hypothesis Involving S-Nitrosation

(2012) Volker Ullrich et al.   ANTIOXIDANTS & REDOX SIGNALING

Sensors, Transmitters, and Targets in Mitochondrial Oxygen Shortage—A Hypoxia-Inducible Factor Relay Story

(2012) Nathalie Dehne et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial Energy Metabolism and Redox Signaling in Brain Aging and Neurodegeneration

(2012) Fei Yin et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial Redox Signaling: Interaction of Mitochondrial Reactive Oxygen Species with Other Sources of Oxidative Stress

(2012) Eberhard Schulz et al.   ANTIOXIDANTS & REDOX SIGNALING

Complex I generated, mitochondrial matrix-directed superoxide is released from the mitochondria through voltage dependent anion channels

(2012) Michael S. Lustgarten et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glucose-independent improvement of vascular dysfunction in experimental sepsis by dipeptidyl-peptidase 4 inhibition

(2012) Swenja Kröller-Schön et al.   CARDIOVASCULAR RESEARCH

Chronic protection against ischemia and reperfusion-induced endothelial dysfunction during therapy with different organic nitrates

(2012) Monica Lisi et al.   Clinical Research in Cardiology

Free radical biology of the cardiovascular system

(2012) Alex F. Chen et al.   CLINICAL SCIENCE

Stress-dependent hypertension and the role of T lymphocytes

(2012) Paul J. Marvar et al.   EXPERIMENTAL PHYSIOLOGY

Mitochondrial ROS-K+channel signaling pathway regulated secretion of human pulmonary artery endothelial cells

(2012) Jin-Sheng Ouyang et al.   FREE RADICAL RESEARCH

Role of Nox isoforms in angiotensin II-induced oxidative stress and endothelial dysfunction in brain

(2012) Sophocles Chrissobolis et al.   JOURNAL OF APPLIED PHYSIOLOGY

Regulation of Endothelial Nitric-oxide Synthase (NOS)S-Glutathionylation by Neuronal NOS

(2012) Winifred O. Idigo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Early redox, Src family kinase, and calcium signaling integrate wound responses and tissue regeneration in zebrafish

(2012) Sa Kan Yoo et al.   JOURNAL OF CELL BIOLOGY

Endothelin-1 increases superoxide production in human coronary artery bypass grafts

(2012) R. Cerrato et al.   LIFE SCIENCES

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death

(2012) Nicholas A Graham et al.   Molecular Systems Biology

Redox regulation of MAPK phosphatase 1 controls monocyte migration and macrophage recruitment

(2012) H. S. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redox regulation of cell migration and adhesion

(2012) Thomas Ryan Hurd et al.   TRENDS IN CELL BIOLOGY

Reduction of Ischemia/Reperfusion Injury With Bendavia, a Mitochondria‐Targeting Cytoprotective Peptide

(2012) Robert A. Kloner et al.   Journal of the American Heart Association

ROS-induced ROS release in vascular biology: redox-redox signaling

(2011) Natalya S. Zinkevich et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Oxidative stress and endothelial dysfunction: Therapeutic implications

(2011) Tommaso Gori et al.   ANNALS OF MEDICINE

Ero1α Regulates Ca2+ Fluxes at the Endoplasmic Reticulum–Mitochondria Interface (MAM)

(2011) Tiziana Anelli et al.   ANTIOXIDANTS & REDOX SIGNALING

Nitroglycerin-Induced Endothelial Dysfunction and Tolerance Involve Adverse Phosphorylation and S -Glutathionylation of Endothelial Nitric Oxide Synthase

(2011) Maike Knorr et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of endothelial Nox2 NADPH oxidase in angiotensin II-induced hypertension and vasomotor dysfunction

(2011) Colin E. Murdoch et al.   BASIC RESEARCH IN CARDIOLOGY

The role of mitochondrial permeability transition in reperfusion-induced cardiomyocyte death depends on the duration of ischemia

(2011) Marisol Ruiz-Meana et al.   BASIC RESEARCH IN CARDIOLOGY

Regulation by mitochondrial superoxide and NADPH oxidase of cellular formation of nitrated cyclic GMP: potential implications for ROS signalling

(2011) Khandaker Ahtesham Ahmed et al.   BIOCHEMICAL JOURNAL

Soluble Guanylate Cyclase as an Emerging Therapeutic Target in Cardiopulmonary Disease

(2011) Johannes-Peter Stasch et al.   CIRCULATION

Lysozyme M–Positive Monocytes Mediate Angiotensin II–Induced Arterial Hypertension and Vascular Dysfunction

(2011) Philip Wenzel et al.   CIRCULATION

Vascular Dysfunction in Experimental Diabetes Is Improved by Pentaerithrityl Tetranitrate but Not Isosorbide-5-Mononitrate Therapy

(2011) S. Schuhmacher et al.   DIABETES

Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation

(2011) Huibin Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cross talk between mitochondria and NADPH oxidases

(2011) Sergey Dikalov   FREE RADICAL BIOLOGY AND MEDICINE

Cysteine 203 of Cyclophilin D Is Critical for Cyclophilin D Activation of the Mitochondrial Permeability Transition Pore

(2011) Tiffany T. Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The E-loop Is Involved in Hydrogen Peroxide Formation by the NADPH Oxidase Nox4

(2011) Ina Takac et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

(2011) Ariel C. Bulua et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeting Mitochondrial Oxidative Stress in Heart Failure

(2011) Christoph Maack et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

Lyn is a redox sensor that mediates leukocyte wound attraction in vivo

(2011) Sa Kan Yoo et al.   NATURE

Protein Disulfide Isomerase and Host-Pathogen Interaction

(2011) Beatriz S. Stolf et al.   TheScientificWorldJOURNAL

The Lifespan-Regulator p66Shc in Mitochondria: Redox Enzyme or Redox Sensor?

(2010) Melanie Gertz et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial Injury and Protection in Ischemic Pre- and Postconditioning

(2010) Fabio Di Lisa et al.   ANTIOXIDANTS & REDOX SIGNALING

Hypoxia Induces Intracellular Ca2+ Release by Causing Reactive Oxygen Species-Mediated Dissociation of FK506-Binding Protein 12.6 from Ryanodine Receptor 2 in Pulmonary Artery Myocytes

(2010) Bo Liao et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox signaling (cross-talk) from and to mitochondria involves mitochondrial pores and reactive oxygen species

(2010) Andreas Daiber   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Redox-optimized ROS balance: A unifying hypothesis

(2010) M.A. Aon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Redox regulation of the mitochondrial KATP channel in cardioprotection

(2010) Bruno B. Queliconi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Silencing Nox4 in the Paraventricular Nucleus Improves Myocardial Infarction–Induced Cardiac Dysfunction by Attenuating Sympathoexcitation and Periinfarct Apoptosis

(2010) David W. Infanger et al.   CIRCULATION RESEARCH

Therapeutic Targeting of Mitochondrial Superoxide in Hypertension

(2010) Anna E. Dikalova et al.   CIRCULATION RESEARCH

Is oxidative stress a therapeutic target in cardiovascular disease?

(2010) Thomas Münzel et al.   EUROPEAN HEART JOURNAL

Organic Nitrates and Nitrate Resistance in Diabetes: The Role of Vascular Dysfunction and Oxidative Stress with Emphasis on Antioxidant Properties of Pentaerithrityl Tetranitrate

(2010) Matthias Oelze et al.   Experimental Diabetes Research

Inflammation, Immunity, and Hypertension

(2010) David G. Harrison et al.   HYPERTENSION

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Residual NADPH Oxidase and Survival in Chronic Granulomatous Disease

(2010) Douglas B. Kuhns et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tolerance to nitroglycerin-induced preconditioning of the endothelium: a human in vivo study

(2009) Tommaso Gori et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Translation-Linked mRNA Destabilization Accompanying Serum-Induced Nox4 Expression in Human Endothelial Cells

(2009) Hitesh Peshavariya et al.   ANTIOXIDANTS & REDOX SIGNALING

Cross-Talk Between Mitochondria and NADPH Oxidase: Effects of Mild Mitochondrial Dysfunction on Angiotensin II-Mediated Increase in Nox Isoform Expression and Activity in Vascular Smooth Muscle Cells

(2009) João Wosniak et al.   ANTIOXIDANTS & REDOX SIGNALING

ROS-Dependent Signaling Mechanisms for Hypoxic Ca2+ Responses in Pulmonary Artery Myocytes

(2009) Yong-Xiao Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Age-related changes in levels of p66Shc and serine 36-phosphorylated p66Shc in organs and mouse tissues

(2009) M. Lebiedzinska et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

NADPH Oxidases: Functions and Pathologies in the Vasculature

(2009) Bernard Lassègue et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Monoamine Oxidase A–Mediated Enhanced Catabolism of Norepinephrine Contributes to Adverse Remodeling and Pump Failure in Hearts With Pressure Overload

(2009) Nina Kaludercic et al.   CIRCULATION RESEARCH

RAGE-Induced Cytosolic ROS Promote Mitochondrial Superoxide Generation in Diabetes

(2009) M. T. Coughlan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Nitric Oxide, Tetrahydrobiopterin, Oxidative Stress, and Endothelial Dysfunction in Hypertension

(2008) Eberhard Schulz et al.   ANTIOXIDANTS & REDOX SIGNALING

First Evidence for a Crosstalk Between Mitochondrial and NADPH Oxidase-Derived Reactive Oxygen Species in Nitroglycerin-Triggered Vascular Dysfunction

(2008) Philip Wenzel et al.   ANTIOXIDANTS & REDOX SIGNALING

Novel Role of Protein Disulfide Isomerase in the Regulation of NADPH Oxidase Activity: Pathophysiological Implications in Vascular Diseases

(2008) Francisco R.M. Laurindo et al.   ANTIOXIDANTS & REDOX SIGNALING

Nox4 Acts as a Switch Between Differentiation and Proliferation in Preadipocytes

(2008) Katrin Schröder et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Redox signaling triggers protection during the reperfusion rather than the ischemic phase of preconditioning

(2008) Turhan Dost et al.   BASIC RESEARCH IN CARDIOLOGY

ALDH-2 deficiency increases cardiovascular oxidative stress---Evidence for indirect antioxidative properties

(2008) Philip Wenzel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Antimycin A and lipopolysaccharide cause the leakage of superoxide radicals from rat liver mitochondria

(2008) Christina Piskernik et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Role of neuronal NO synthase in regulating vascular superoxide levels and mitogen-activated protein kinase phosphorylation

(2008) G.-X. Zhang et al.   CARDIOVASCULAR RESEARCH

Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction

(2008) Philip Wenzel et al.   CARDIOVASCULAR RESEARCH

Superoxide Flashes in Single Mitochondria

(2008) Wang Wang et al.   CELL

Nitroglycerin-Induced S-nitrosylation and Desensitization of Soluble Guanylyl Cyclase Contribute to Nitrate Tolerance

(2008) Nazish Sayed et al.   CIRCULATION RESEARCH

Insights into the redox biology of Trypanosoma cruzi: Trypanothione metabolism and oxidant detoxification

(2008) Florencia Irigoín et al.   FREE RADICAL BIOLOGY AND MEDICINE

Endogenous peroxynitrite modulates PGHS-1–dependent thromboxane A2 formation and aggregation in human platelets

(2008) Stefan Schildknecht et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2+]i through the mitochondrial ROS-PKCɛ signaling axis in pulmonary artery smooth muscle cells

(2008) R RATHORE et al.   FREE RADICAL BIOLOGY AND MEDICINE

Involvement of Nox2 NADPH Oxidase in Adverse Cardiac Remodeling After Myocardial Infarction

(2008) Yee H. Looi et al.   HYPERTENSION

The Mechanism of Mitochondrial Superoxide Production by the Cytochromebc1Complex

(2008) Stefan Dröse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox properties of the adenoside triphosphate-sensitive K+ channel in brain mitochondria

(2008) Maynara Fornazari et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Nitrate-Induced Toxicity and Preconditioning

(2008) Tommaso Gori et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effect of Cyclosporine on Reperfusion Injury in Acute Myocardial Infarction

(2008) Christophe Piot et al.   NEW ENGLAND JOURNAL OF MEDICINE

Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart

(2008) Che-Hong Chen et al.   SCIENCE

Regulation of Proliferation of Skeletal Muscle Precursor Cells By NADPH Oxidase

(2007) Mahroo Mofarrahi et al.   ANTIOXIDANTS & REDOX SIGNALING

Molecular Mechanisms of Angiotensin II–Mediated Mitochondrial Dysfunction

(2007) Abdulrahman K. Doughan et al.   CIRCULATION RESEARCH