More answers to the still unresolved question of nitrate tolerance

Management of Stable Ischemic Heart Disease: Summary of a Clinical Practice Guideline From the American College of Physicians/American College of Cardiology Foundation/American Heart Association/American Association for Thoracic Surgery/Preventive Cardiovascular Nurses Association/Society of Thoracic Surgeons

(2013) Amir Qaseem   ANNALS OF INTERNAL MEDICINE

Nitrite Signaling in Pulmonary Hypertension: Mechanisms of Bioactivation, Signaling, and Therapeutics

(2012) Marta Bueno et al.   ANTIOXIDANTS & REDOX SIGNALING

P300/CBP Associated Factor Regulates Nitroglycerin-Dependent Arterial Relaxation by N ε -Lysine Acetylation of Contractile Proteins

(2012) Claudia Colussi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Dietary Nitrate Supplementation Improves Revascularization in Chronic Ischemia

(2012) Ulrike B. Hendgen-Cotta et al.   CIRCULATION

Nitrite activates AMP kinase to stimulate mitochondrial biogenesis independent of soluble guanylate cyclase

(2012) Li Mo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Vascular Bioactivation of Nitroglycerin by Aldehyde Dehydrogenase-2

(2012) Barbara S. Lang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nitroglycerin-Induced Endothelial Dysfunction and Tolerance Involve Adverse Phosphorylation and S -Glutathionylation of Endothelial Nitric Oxide Synthase

(2011) Maike Knorr et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nitrate Therapy

(2011) Thomas Münzel et al.   CIRCULATION

Regulation of Human Mitochondrial Aldehyde Dehydrogenase (ALDH-2) Activity by Electrophilesin Vitro

(2011) Matthias Oelze et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Is oxidative stress a therapeutic target in cardiovascular disease?

(2010) Thomas Münzel et al.   EUROPEAN HEART JOURNAL

Pentaerythritol Tetranitrate Improves Angiotensin II–Induced Vascular Dysfunction via Induction of Heme Oxygenase-1

(2010) Swenja Schuhmacher et al.   HYPERTENSION

Standard versus Low-Dose Transdermal Nitroglycerin: Differential Effects on the Development of Tolerance and Abnormalities of Endothelial Function

(2010) Amar Uxa et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Bioactivation of Pentaerythrityl Tetranitrate by Mitochondrial Aldehyde Dehydrogenase

(2010) M. Griesberger et al.   MOLECULAR PHARMACOLOGY

Dietary nitrite prevents hypercholesterolemic microvascular inflammation and reverses endothelial dysfunction

(2009) Karen Y. Stokes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Tolerance to nitroglycerin-induced preconditioning of the endothelium: a human in vivo study

(2009) Tommaso Gori et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Effects of pentaerythritol tetranitrate on endothelial function in coronary artery disease: results of the PENTA study

(2009) Boris Schnorbus et al.   Clinical Research in Cardiology

Chronic nitrate therapy is associated with different presentation and evolution of acute coronary syndromes: insights from 52 693 patients in the Global Registry of Acute Coronary Events

(2009) G. Ambrosio et al.   EUROPEAN HEART JOURNAL

Gastroprotective and blood pressure lowering effects of dietary nitrate are abolished by an antiseptic mouthwash

(2009) Joel Petersson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of the General Base Glu-268 in Nitroglycerin Bioactivation and Superoxide Formation by Aldehyde Dehydrogenase-2

(2009) M. Verena Wenzl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

First Evidence for a Crosstalk Between Mitochondrial and NADPH Oxidase-Derived Reactive Oxygen Species in Nitroglycerin-Triggered Vascular Dysfunction

(2008) Philip Wenzel et al.   ANTIOXIDANTS & REDOX SIGNALING

Effect of oral organic nitrates on expression and activity of vascular soluble guanylyl cyclase

(2008) M Oppermann et al.   BRITISH JOURNAL OF PHARMACOLOGY

Nitroglycerin-Induced S-nitrosylation and Desensitization of Soluble Guanylyl Cyclase Contribute to Nitrate Tolerance

(2008) Nazish Sayed et al.   CIRCULATION RESEARCH

Acute Blood Pressure Lowering, Vasoprotective, and Antiplatelet Properties of Dietary Nitrate via Bioconversion to Nitrite

(2008) Andrew J. Webb et al.   HYPERTENSION

Nitric Oxide Production from Nitrite Occurs Primarily in Tissues Not in the Blood

(2008) Haitao Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY