Empagliflozin Limits Myocardial Infarction in Vivo and Cell Death in Vitro: Role of STAT3, Mitochondria, and Redox Aspects

Dapagliflozin, a selective SGLT2 Inhibitor, attenuated cardiac fibrosis by regulating the macrophage polarization via STAT3 signaling in infarcted rat hearts

(2017) Tsung-Ming Lee et al.   FREE RADICAL BIOLOGY AND MEDICINE

The efficacy and safety of SGLT2 inhibitors for adjunctive treatment of type 1 diabetes: a systematic review and meta-analysis

(2017) Jiao Chen et al.   Scientific Reports

The SGLT2 inhibitor empagliflozin improves the primary diabetic complications in ZDF rats

(2017) Sebastian Steven et al.   Redox Biology

Exposure to cigarette smoke abrogates the beneficial effect of ischemic postconditioning

(2016) Sofia-Iris Bibli et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery

(2016) Derek J. Hausenloy et al.   BASIC RESEARCH IN CARDIOLOGY

Interleukin-17A mediates cardiomyocyte apoptosis through Stat3-iNOS pathway

(2016) Sheng-an Su et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels

(2016) Simon A. Hawley et al.   DIABETES

Empagliflozin decreases myocardial cytoplasmic Na+ through inhibition of the cardiac Na+/H+ exchanger in rats and rabbits

(2016) Antonius Baartscheer et al.   DIABETOLOGIA

Heart failure outcomes with empagliflozin in patients with type 2 diabetes at high cardiovascular risk: results of the EMPA-REG OUTCOME®trial

(2016) David Fitchett et al.   EUROPEAN HEART JOURNAL

The Effects of Empagliflozin, an SGLT2 Inhibitor, on Pancreatic β-Cell Mass and Glucose Homeostasis in Type 1 Diabetes

(2016) Sam Tsz Wai Cheng et al.   PLoS One

Redox signalling and cardioprotection: translatability and mechanism

(2015) P Pagliaro et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cardioprotection by H2S engages a cGMP-dependent protein kinase G/phospholamban pathway

(2015) Sofia-Iris Bibli et al.   CARDIOVASCULAR RESEARCH

Molecular Basis of Cardioprotection: Signal Transduction in Ischemic Pre-, Post-, and Remote Conditioning

(2015) G. Heusch   CIRCULATION RESEARCH

Transient carotid ischemia as a remote conditioning stimulus for myocardial protection in anesthetized rabbits: Insights into intracellular signaling

(2015) Ioanna Andreadou et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

RAGE siRNA-mediated gene silencing provides cardioprotection against ventricular arrhythmias in acute ischemia and reperfusion

(2015) Hyelim Park et al.   JOURNAL OF CONTROLLED RELEASE

The mitochondrial permeability transition pore: Molecular nature and role as a target in cardioprotection

(2015) Paolo Bernardi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Tumor necrosis factor-α confers cardioprotection through ectopic expression of keratins K8 and K18

(2015) Stamatis Papathanasiou et al.   NATURE MEDICINE

The Sodium-Glucose Co-Transporter 2 Inhibitor Empagliflozin Improves Diabetes-Induced Vascular Dysfunction in the Streptozotocin Diabetes Rat Model by Interfering with Oxidative Stress and Glucotoxicity

(2014) Matthias Oelze et al.   PLoS One

Role of oxidants on calcium and sodium movement in healthy and diseased cardiac myocytes

(2013) Can M. Sag et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of SGLT2 Inhibition in Human Kidney Proximal Tubular Cells—Renoprotection in Diabetic Nephropathy?

(2013) Usha Panchapakesan et al.   PLoS One

Effects of diabetes on myocardial infarct size and cardioprotection by preconditioning and postconditioning

(2012) Takayuki Miki et al.   Cardiovascular Diabetology

Short-term statin administration in hypercholesterolaemic rabbits resistant to postconditioning: effects on infarct size, endothelial nitric oxide synthase, and nitro-oxidative stress

(2012) I. Andreadou et al.   CARDIOVASCULAR RESEARCH

Multiple Facets of NF-κB in the Heart

(2011) Joseph W. Gordon et al.   CIRCULATION RESEARCH

RETRACTED ARTICLE: MIR221/MIR222-driven post-transcriptional regulation of P27KIP1 and P57KIP2 is crucial for high-glucose- and AGE-mediated vascular cell damage

(2011) G. Togliatto et al.   DIABETOLOGIA