Free radical biology of the cardiovascular system

Caffeine Intake and Dementia: Systematic Review and Meta-Analysis

(2017) Catarina Santos et al.   JOURNAL OF ALZHEIMERS DISEASE

Allopurinol, Xanthine Oxidase, and Cardiac Ischemia

(2016) Brian E. Lee et al.   JOURNAL OF INVESTIGATIVE MEDICINE

AMP-activated protein kinase rescues the angiogenic functions of endothelial progenitor cells via manganese superoxide dismutase induction in type 1 diabetes

(2011) Xiao-Rong Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Vascular Dysfunction in Experimental Diabetes Is Improved by Pentaerithrityl Tetranitrate but Not Isosorbide-5-Mononitrate Therapy

(2011) S. Schuhmacher et al.   DIABETES

Short-term calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress

(2010) Catarina Rippe et al.   AGING CELL

MicroRNA-34a induces endothelial progenitor cell senescence and impedes its angiogenesis via suppressing silent information regulator 1

(2010) Ting Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Redox signaling (cross-talk) from and to mitochondria involves mitochondrial pores and reactive oxygen species

(2010) Andreas Daiber   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The Promise of Cell-Based Therapies for Diabetic Complications

(2010) Yagna P.R. Jarajapu et al.   CIRCULATION RESEARCH

Therapeutic Targeting of Mitochondrial Superoxide in Hypertension

(2010) Anna E. Dikalova et al.   CIRCULATION RESEARCH

Unacylated Ghrelin Rescues Endothelial Progenitor Cell Function in Individuals With Type 2 Diabetes

(2010) G. Togliatto et al.   DIABETES

Potential manipulation of endothelial progenitor cells in diabetes and its complications

(2010) G. P. Fadini et al.   DIABETES OBESITY & METABOLISM

Angiotensin II revisited: new roles in inflammation, immunology and aging

(2010) Ariela Benigni et al.   EMBO Molecular Medicine

Pentaerythritol Tetranitrate Improves Angiotensin II–Induced Vascular Dysfunction via Induction of Heme Oxygenase-1

(2010) Swenja Schuhmacher et al.   HYPERTENSION

GTP Cyclohydrolase I/BH4 Pathway Protects EPCs via Suppressing Oxidative Stress and Thrombospondin-1 in Salt-Sensitive Hypertension

(2010) He-Hui Xie et al.   HYPERTENSION

Induction of Manganese Superoxide Dismutase by Nuclear Translocation and Activation of SIRT1 Promotes Cell Survival in Chronic Heart Failure

(2010) Masaya Tanno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Does Peroxisome Proliferator-activated Receptor-γ (PPARγ) Protect from Hypertension Directly through Effects in the Vasculature?

(2010) Pimonrat Ketsawatsomkron et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Manganese superoxide dismutase expression in endothelial progenitor cells accelerates wound healing in diabetic mice

(2010) Eric J. Marrotte et al.   JOURNAL OF CLINICAL INVESTIGATION

Resveratrol Reverses Endothelial Nitric-Oxide Synthase Uncoupling in Apolipoprotein E Knockout Mice

(2010) N. Xia et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Mechanisms of Vascular Aging: New Perspectives

(2010) Z. Ungvari et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Endothelial dysfunction in aged humans is related with oxidative stress and vascular inflammation

(2009) Leocadio Rodríguez-Mañas et al.   AGING CELL

Role of oxidative stress and AT1 receptors in cerebral vascular dysfunction with aging

(2009) Mary L. Modrick et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Small-Molecule NOX Inhibitors: ROS-Generating NADPH Oxidases as Therapeutic Targets

(2009) Vincent Jaquet et al.   ANTIOXIDANTS & REDOX SIGNALING

p66ShcA modulates oxidative stress and survival of endothelial progenitor cells in response to high glucose

(2009) Valeria Di Stefano et al.   CARDIOVASCULAR RESEARCH

Age-Accelerated Atherosclerosis Correlates With Failure to Upregulate Antioxidant Genes

(2009) Alan R. Collins et al.   CIRCULATION RESEARCH

Prevention of Atherosclerosis by Interference with the Vascular Nitric Oxide System

(2009) Huige Li et al.   CURRENT PHARMACEUTICAL DESIGN

TIMP3 Is Reduced in Atherosclerotic Plaques From Subjects With Type 2 Diabetes and Increased by SirT1

(2009) M. Cardellini et al.   DIABETES

Klotho Gene Delivery Prevents the Progression of Spontaneous Hypertension and Renal Damage

(2009) Yuhong Wang et al.   HYPERTENSION

Targeted Detoxification of Selected Reactive Oxygen Species in the Vascular Endothelium

(2009) V. V. Shuvaev et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Voluntary wheel running restores endothelial function in conduit arteries of old mice: direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down-regulation of NADPH oxidase

(2009) Jessica R. Durrant et al.   JOURNAL OF PHYSIOLOGY-LONDON

Aging decreases expression and activity of glutathione peroxidase-1 in human endothelial progenitor cells

(2009) Tongrong He et al.   MICROVASCULAR RESEARCH

Klotho

(2009) Makoto Kuro-o   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Effects of nitroglycerin or pentaerithrityl tetranitrate treatment on the gene expression in rat hearts: evidence for cardiotoxic and cardioprotective effects

(2009) Andrea Pautz et al.   PHYSIOLOGICAL GENOMICS

Pparγ2 Is a Key Driver of Longevity in the Mouse

(2009) Carmen Argmann et al.   PLoS Genetics

Nitric Oxide, Tetrahydrobiopterin, Oxidative Stress, and Endothelial Dysfunction in Hypertension

(2008) Eberhard Schulz et al.   ANTIOXIDANTS & REDOX SIGNALING

First Evidence for a Crosstalk Between Mitochondrial and NADPH Oxidase-Derived Reactive Oxygen Species in Nitroglycerin-Triggered Vascular Dysfunction

(2008) Philip Wenzel et al.   ANTIOXIDANTS & REDOX SIGNALING

SIRT1, a Longevity Gene, Downregulates Angiotensin II Type 1 Receptor Expression in Vascular Smooth Muscle Cells

(2008) Ryohei Miyazaki et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction

(2008) Philip Wenzel et al.   CARDIOVASCULAR RESEARCH

Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice

(2008) Q.-j. Zhang et al.   CARDIOVASCULAR RESEARCH

The Sirtuin family: therapeutic targets to treat diseases of aging

(2008) Jill C Milne et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Differential vascular functions of Nox family NADPH oxidases

(2008) Ralf P Brandes et al.   CURRENT OPINION IN LIPIDOLOGY

NADPH Oxidases, Reactive Oxygen Species, and Hypertension: Clinical implications and therapeutic possibilities

(2008) T. M. Paravicini et al.   DIABETES CARE

Differential roles of PKCα and PKCɛ in controlling the gene expression of Nox4 in human endothelial cells

(2008) Hui Xu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Interference With PPARγ Signaling Causes Cerebral Vascular Dysfunction, Hypertrophy, and Remodeling

(2008) Andreas M. Beyer et al.   HYPERTENSION

Pharmacological induction of vascular extracellular superoxide dismutase expressionin vivo

(2008) Marc Oppermann et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Complete Rescue of Cerebrovascular Function in Aged Alzheimer's Disease Transgenic Mice by Antioxidants and Pioglitazone, a Peroxisome Proliferator-Activated Receptor   Agonist

(2008) N. Nicolakakis et al.   JOURNAL OF NEUROSCIENCE

Klotho is a target gene of PPAR-γ

(2008) Hong Zhang et al.   KIDNEY INTERNATIONAL

Effects of succinobucol (AGI-1067) after an acute coronary syndrome: a randomised, double-blind, placebo-controlled trial

(2008) Jean-Claude Tardif et al.   LANCET

Effect of Cyclosporine on Reperfusion Injury in Acute Myocardial Infarction

(2008) Christophe Piot et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sirt1 protects against high-fat diet-induced metabolic damage

(2008) P. T. Pfluger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of oxidative stress and NADPH oxidase in cerebrovascular disease

(2008) Sophocles Chrissobolis et al.   TRENDS IN MOLECULAR MEDICINE

Oxidative stress in vascular disease: causes, defense mechanisms and potential therapies

(2008) Ulrich Förstermann   Nature clinical practice. Cardiovascular medicine

Apocynin Is Not an Inhibitor of Vascular NADPH Oxidases but an Antioxidant

(2007) Sabine Heumüller et al.   HYPERTENSION