Mitochondria-targeted antioxidant (MitoQ) ameliorates age-related arterial endothelial dysfunction in mice

Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice

(2013) Anthony J. Donato et al.   AGING CELL

Mitochondria and Endothelial Function

(2013) Matthew A. Kluge et al.   CIRCULATION RESEARCH

The autophagy enhancer spermidine reverses arterial aging

(2013) Thomas J. LaRocca et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Mitochondrial dysfunction and the inflammatory response

(2013) María J. López-Armada et al.   MITOCHONDRION

Protein Tyrosine Nitration: Biochemical Mechanisms and Structural Basis of Functional Effects

(2012) Rafael Radi   ACCOUNTS OF CHEMICAL RESEARCH

Vascular aging: Chronic oxidative stress and impairment of redox signaling—consequences for vascular homeostasis and disease

(2012) Markus M. Bachschmid et al.   ANNALS OF MEDICINE

Mitochondria in Vascular Health and Disease

(2012) Peter Dromparis et al.   Annual Review of Physiology

Mitochondria: In Sickness and in Health

(2012) Jodi Nunnari et al.   CELL

Mitochondria and Cardiovascular Aging

(2012) Dao-Fu Dai et al.   CIRCULATION RESEARCH

Mitochondrial Control of Cellular Life, Stress, and Death

(2012) Lorenzo Galluzzi et al.   CIRCULATION RESEARCH

Sodium nitrite de-stiffening of large elastic arteries with aging: Role of normalization of advanced glycation end-products

(2012) Bradley S. Fleenor et al.   EXPERIMENTAL GERONTOLOGY

Curcumin ameliorates arterial dysfunction and oxidative stress with aging

(2012) Bradley S. Fleenor et al.   EXPERIMENTAL GERONTOLOGY

Translational evidence that impaired autophagy contributes to arterial ageing

(2012) Thomas J. LaRocca et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mitochondrial pharmacology

(2012) Robin A.J. Smith et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Nitrite supplementation reverses vascular endothelial dysfunction and large elastic artery stiffness with aging

(2011) Amy L. Sindler et al.   AGING CELL

Altered Mitochondrial Dynamics Contributes to Endothelial Dysfunction in Diabetes Mellitus

(2011) Sherene M. Shenouda et al.   CIRCULATION

Heart Disease and Stroke Statistics—2012 Update

(2011) et al.   CIRCULATION

Short-term calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress

(2010) Catarina Rippe et al.   AGING CELL

Animal and human studies with the mitochondria-targeted antioxidant MitoQ

(2010) Robin A.J. Smith et al.   Annals of the New York Academy of Sciences

The Lifespan-Regulator p66Shc in Mitochondria: Redox Enzyme or Redox Sensor?

(2010) Melanie Gertz et al.   ANTIOXIDANTS & REDOX SIGNALING

Therapeutic Targeting of Mitochondrial Superoxide in Hypertension

(2010) Anna E. Dikalova et al.   CIRCULATION RESEARCH

Impaired quality control of mitochondria: Aging from a new perspective

(2010) Tobias A. Weber et al.   EXPERIMENTAL GERONTOLOGY

Emerging mitochondrial signaling mechanisms in physiology, aging processes, and as drug targets

(2010) Mahadevan Lakshminarasimhan et al.   EXPERIMENTAL GERONTOLOGY

EPR detection of cellular and mitochondrial superoxide using cyclic hydroxylamines

(2010) Sergey I. Dikalov et al.   FREE RADICAL RESEARCH

The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients

(2010) Edward J. Gane et al.   LIVER INTERNATIONAL

A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease

(2010) Barry J. Snow et al.   MOVEMENT DISORDERS

Endothelial dysfunction and aging: An update

(2009) María Dolores Herrera et al.   AGEING RESEARCH REVIEWS

PGC-1α in aging and anti-aging interventions

(2009) Rozalyn Anderson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice

(2009) Sergio Rodriguez-Cuenca et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondria-Targeted Antioxidant MitoQ 10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy

(2009) Delyth Graham et al.   HYPERTENSION

Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats

(2008) Zoltan Ungvari et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Rapid and extensive uptake and activation of hydrophobic triphenylphosphonium cations within cells

(2008) Meredith F. Ross et al.   BIOCHEMICAL JOURNAL

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction

(2008) Philip Wenzel et al.   CARDIOVASCULAR RESEARCH