The Role and Therapeutic Targeting of JAK/STAT Signaling in Glioblastoma
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Title
The Role and Therapeutic Targeting of JAK/STAT Signaling in Glioblastoma
Authors
Keywords
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Journal
Cancers
Volume 13, Issue 3, Pages 437
Publisher
MDPI AG
Online
2021-01-25
DOI
10.3390/cancers13030437
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- IL-6 promotion of glioblastoma cell invasion and angiogenesis in U251 and T98G cell lines
- (2010) Qinglin Liu et al. JOURNAL OF NEURO-ONCOLOGY
- STAT3 tyrosine phosphorylation influences survival in glioblastoma
- (2010) Peter Birner et al. JOURNAL OF NEURO-ONCOLOGY
- Inhibition of the JAK-2/STAT3 signaling pathway impedes the migratory and invasive potential of human glioblastoma cells
- (2010) Christian Senft et al. JOURNAL OF NEURO-ONCOLOGY
- Activation of JAK/STAT signal pathway predicts poor prognosis of patients with gliomas
- (2010) Yanyang Tu et al. MEDICAL ONCOLOGY
- Sorafenib Induces Growth Arrest and Apoptosis of Human Glioblastoma Cells through the Dephosphorylation of Signal Transducers and Activators of Transcription 3
- (2010) Fan Yang et al. MOLECULAR CANCER THERAPEUTICS
- Curcumin inhibits tumor growth and angiogenesis in glioblastoma xenografts
- (2010) Marie-Claude Perry et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Glioma cancer stem cells induce immunosuppressive macrophages/microglia
- (2010) Adam Wu et al. NEURO-ONCOLOGY
- STAT5 regulates glioma cell invasion by pathways dependent and independent of STAT5 DNA binding
- (2010) Shouqiang Cao et al. NEUROSCIENCE LETTERS
- Activated STAT3 Regulates Hypoxia-Induced Angiogenesis and Cell Migration in Human Glioblastoma
- (2010) Shin-Hyuk Kang et al. NEUROSURGERY
- IL-6 augments the invasiveness of U87MG human glioblastoma multiforme cells via up-regulation of MMP-2 and fascin-1
- (2010) Li ONCOLOGY REPORTS
- A study of high-dose oral silybin-phytosome followed by prostatectomy in patients with localized prostate cancer
- (2010) Thomas W. Flaig et al. PROSTATE
- Inhibition of STAT3 reverses drug resistance acquired in temozolomide-resistant human glioma cells
- (2010) EUN-SANG LEE et al. Oncology Letters
- STAT1 represses hypoxia-inducible factor-1-mediated transcription
- (2009) Miki Hiroi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Early termination of ISRCTN45828668, a phase 1/2 prospective, randomized study of Sulfasalazine for the treatment of progressing malignant gliomas in adults
- (2009) Pierre A Robe et al. BMC CANCER
- LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model
- (2009) B Fuh et al. BRITISH JOURNAL OF CANCER
- Regulation of the IL-23 and IL-12 Balance by Stat3 Signaling in the Tumor Microenvironment
- (2009) Marcin Kortylewski et al. CANCER CELL
- TGF-β Increases Glioma-Initiating Cell Self-Renewal through the Induction of LIF in Human Glioblastoma
- (2009) Silvia Peñuelas et al. CANCER CELL
- Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice
- (2009) Leying Zhang et al. GLIA
- Relationship between peroxisome proliferator-activated receptor-γ activation and the ameliorative effects of ascochlorin derivatives on type II diabetes
- (2009) Junji Magae et al. JOURNAL OF ANTIBIOTICS
- Antitumor effect of humanized anti–interleukin-6 receptor antibody (tocilizumab) on glioma cell proliferation
- (2009) Mareina Kudo et al. JOURNAL OF NEUROSURGERY
- Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers
- (2009) Luis Almeida et al. MOLECULAR NUTRITION & FOOD RESEARCH
- In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses
- (2009) Marcin Kortylewski et al. NATURE BIOTECHNOLOGY
- The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers
- (2009) S. Veeriah et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor Growth
- (2009) Hui Wang et al. STEM CELLS
- STAT3 Is Required for Proliferation and Maintenance of Multipotency in Glioblastoma Stem Cells
- (2009) Maureen M. Sherry et al. STEM CELLS
- Inhibition of transcription factor STAT5b suppresses proliferation, induces G1 cell cycle arrest and reduces tumor cell invasion in human glioblastoma multiforme cells
- (2008) Qin-Chuan Liang et al. CANCER LETTERS
- Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells
- (2008) Xi Chen et al. CELL
- Constitutively Activated STAT3 Frequently Coexpresses with Epidermal Growth Factor Receptor in High-Grade Gliomas and Targeting STAT3 Sensitizes Them to Iressa and Alkylators
- (2008) H.-W. Lo et al. CLINICAL CANCER RESEARCH
- Loss of Protein Inhibitors of Activated STAT-3 Expression in Glioblastoma Multiforme Tumors: Implications for STAT-3 Activation and Gene Expression
- (2008) E. C. Brantley et al. CLINICAL CANCER RESEARCH
- The Incidence, Correlation with Tumor-Infiltrating Inflammation, and Prognosis of Phosphorylated STAT3 Expression in Human Gliomas
- (2008) M. Abou-Ghazal et al. CLINICAL CANCER RESEARCH
- Protein tyrosine phosphatases in the JAK/STAT pathway
- (2008) Dan Xu Frontiers in Bioscience-Landmark
- Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway
- (2008) N. de la Iglesia et al. GENES & DEVELOPMENT
- Immunomodulatory and anticancer effects of intra-tumoral co-delivery of synthetic lipid A adjuvant and STAT3 inhibitor, JSI-124
- (2008) Ommoleila Molavi et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Prognostic relevance of SOCS3 hypermethylation in patients with glioblastoma multiforme
- (2008) Maurizio Martini et al. INTERNATIONAL JOURNAL OF CANCER
- Blockage of the STAT3 signaling pathway with a decoy oligonucleotide suppresses growth of human malignant glioma cells
- (2008) Jinhai Gu et al. JOURNAL OF NEURO-ONCOLOGY
- Deregulation of a STAT3-Interleukin 8 Signaling Pathway Promotes Human Glioblastoma Cell Proliferation and Invasiveness
- (2008) N. de la Iglesia et al. JOURNAL OF NEUROSCIENCE
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
- Induction of MGMT expression is associated with temozolomide resistance in glioblastoma xenografts
- (2008) Gaspar J. Kitange et al. NEURO-ONCOLOGY
- The Role of Fascin in the Migration and Invasiveness of Malignant Glioma Cells
- (2008) Jeong Hyun Hwang et al. NEOPLASIA
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