miR-519a enhances chemosensitivity and promotes autophagy in glioblastoma by targeting STAT3/Bcl2 signaling pathway

The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma

(2017) Giovanni Luca Gravina et al.   Journal of Hematology & Oncology

The role of stromal cancer-associated fibroblasts in pancreatic cancer

(2017) Dagny von Ahrens et al.   Journal of Hematology & Oncology

Therapeutic strategies of drug repositioning targeting autophagy to induce cancer cell death: from pathophysiology to treatment

(2017) Go J. Yoshida   Journal of Hematology & Oncology

Pharmacokinetic analysis and pharmacodynamic evidence of autophagy inhibition in patients with newly diagnosed glioblastoma treated on a phase I trial of hydroxychloroquine in combination with adjuvant temozolomide and radiation (ABTC 0603).

(2017) M. R. Rosenfeld et al.   JOURNAL OF CLINICAL ONCOLOGY

β-Elemene enhances the efficacy of gefitinib on glioblastoma multiforme cells through the inhibition of the EGFR signaling pathway

(2016) Lin Mu et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Immune phenotypes predict survival in patients with glioblastoma multiforme

(2016) Haouraa Mostafa et al.   Journal of Hematology & Oncology

The D Domain of LRRC4 anchors ERK1/2 in the cytoplasm and competitively inhibits MEK/ERK activation in glioma cells

(2016) Zeyou Wang et al.   Journal of Hematology & Oncology

MiR-519a functions as a tumor suppressor in glioma by targeting the oncogenic STAT3 pathway

(2016) Li Hong et al.   JOURNAL OF NEURO-ONCOLOGY

Autophagy enhancement contributes to the synergistic effect of vitamin D in temozolomide-based glioblastoma chemotherapy

(2016) DONG-HO BAK et al.   Experimental and Therapeutic Medicine

The Inhibition of microRNA-128 on IGF-1-Activating mTOR Signaling Involves in Temozolomide-Induced Glioma Cell Apoptotic Death

(2016) Peng-Hsu Chen et al.   PLoS One

MIR517Cinhibits autophagy and the epithelial-to-mesenchymal (-like) transition phenotype in human glioblastoma through KPNA2-dependent disruption of TP53 nuclear translocation

(2015) Yuntao Lu et al.   Autophagy

The role of STAT3 in autophagy

(2015) Liangkun You et al.   Autophagy

The synergistic effect of combination temozolomide and chloroquine treatment is dependent on autophagy formation and p53 status in glioma cells

(2015) Seung Woo Lee et al.   CANCER LETTERS

Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas

(2015) Alfeu Zanotto-Filho et al.   CANCER LETTERS

MiRNA-based therapeutic intervention of cancer

(2015) Srivatsava Naidu et al.   Journal of Hematology & Oncology

TMEM140 is associated with the prognosis of glioma by promoting cell viability and invasion

(2015) Bin Li et al.   Journal of Hematology & Oncology

Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells

(2014) Ugur Akar et al.   Autophagy

Microrna expression signatures predict patient progression and disease outcome in pediatric embryonal central nervous system neoplasms

(2014) Maria Braoudaki et al.   Journal of Hematology & Oncology

Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling

(2014) Y Feng et al.   Cell Death & Disease

Targeting miR-21 Induces Autophagy and Chemosensitivity of Leukemia Cells

(2013) Hugo Seca et al.   CURRENT DRUG TARGETS

Proteome-wide discovery of mislocated proteins in cancer

(2013) K. Lee et al.   GENOME RESEARCH

STAT inhibitors for cancer therapy

(2013) Muhammad Furqan et al.   Journal of Hematology & Oncology

Hypoxia-Induced Autophagy Promotes Tumor Cell Survival and Adaptation to Antiangiogenic Treatment in Glioblastoma

(2012) Y.-L. Hu et al.   CANCER RESEARCH

Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells

(2012) Caroline Happold et al.   JOURNAL OF NEUROCHEMISTRY

Inhibition of Mitochondria- and Endoplasmic Reticulum Stress-Mediated Autophagy Augments Temozolomide-Induced Apoptosis in Glioma Cells

(2012) Chien-Ju Lin et al.   PLoS One

Identification of an Annonaceous Acetogenin Mimetic, AA005, as an AMPK Activator and Autophagy Inducer in Colon Cancer Cells

(2012) Yong-Qiang Liu et al.   PLoS One

Autophagy precedes apoptosis during the remodeling of silkworm larval midgut

(2011) Eleonora Franzetti et al.   APOPTOSIS

PARP and RIP 1 are required for autophagy induced by 11'-deoxyverticillin A, which precedes caspase-dependent apoptosis

(2011) Nan Zhang et al.   Autophagy

Stimulation of the midkine/ALK axis renders glioma cells resistant to cannabinoid antitumoral action

(2011) M Lorente et al.   CELL DEATH AND DIFFERENTIATION

MicroRNA-30a Sensitizes Tumor Cells to cis-Platinum via Suppressing Beclin 1-mediated Autophagy

(2011) Zhenyou Zou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cathepsin B facilitates autophagy-mediated apoptosis in SPARC overexpressed primitive neuroectodermal tumor cells

(2010) P Bhoopathi et al.   CELL DEATH AND DIFFERENTIATION

CyberKnife® enhanced conventionally fractionated chemoradiation for high grade glioma in close proximity to critical structures

(2010) Eric Oermann et al.   Journal of Hematology & Oncology

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Life and death partners: apoptosis, autophagy and the cross-talk between them

(2009) A Eisenberg-Lerner et al.   CELL DEATH AND DIFFERENTIATION

Stat3 activation is required for the growth of U87 cell-derived tumours in mice

(2009) Atreyi Dasgupta et al.   EUROPEAN JOURNAL OF CANCER

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

Signal Transducer and Activator of Transcription-3: A Molecular Hub for Signaling Pathways in Gliomas

(2008) E. C. Brantley et al.   MOLECULAR CANCER RESEARCH