Silencing microRNA‐221/222 cluster suppresses glioblastoma angiogenesis by suppressor of cytokine signaling‐3‐dependent JAK/STAT pathway

Long noncoding RNA-RNCR3 overexpression deleteriously affects the growth of glioblastoma cells through miR-185-5p/Krüppel-like factor 16 axis

(2018) Liang Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Angiogenesis and radiological tumor growth in patients with glioblastoma

(2018) Vilde Elisabeth Mikkelsen et al.   BMC CANCER

Hairless regulates p53 target genes to exert tumor suppressive functions in glioblastoma

(2018) Lemlem Brook et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The mechanical and pharmacological regulation of glioblastoma cell migration in 3D matrices

(2018) Pranita Kaphle et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The correlation between microRNA-221/222 cluster overexpression and malignancy: an updated meta-analysis including 2693 patients

(2018) Pengfei Zhang et al.   Cancer Management and Research

An HNF4α–microRNA-194/192 signaling axis maintains hepatic cell function

(2017) Aoi Morimoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PT93, a novel caffeic acid amide derivative, suppresses glioblastoma cells migration, proliferation and MMP-2/−9 expression

(2017) Kaishu Li et al.   Oncology Letters

miR-221/222 enhance the tumorigenicity of human breast cancer stem cells via modulation of PTEN/Akt pathway

(2016) Bailong Li et al.   BIOMEDICINE & PHARMACOTHERAPY

New Insights Into miR-17–92 Cluster Regulation and Angiogenesis

(2016) Jan Fiedler et al.   CIRCULATION RESEARCH

Platelets from glioblastoma patients promote angiogenesis of tumor endothelial cells and exhibit increased VEGF content and release

(2016) Clara Di Vito et al.   PLATELETS

Epithelial ovarian cancer-secreted exosomal miR-222-3p induces polarization of tumor-associated macrophages

(2016) Xiang Ying et al.   Oncotarget

The Angiogenic Effect of microRNA-21 Targeting TIMP3 through the Regulation of MMP2 and MMP9

(2016) Jianzhong Hu et al.   PLoS One

Calpastatin Counteracts Pathological Angiogenesis by Inhibiting Suppressor of Cytokine Signaling 3 Degradation in Vascular Endothelial CellsNovelty and Significance

(2015) Takuro Miyazaki et al.   CIRCULATION RESEARCH

miR-21 Is Linked to Glioma Angiogenesis

(2015) Simon Kjær Hermansen et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

MicroRNA-221/222 regulate ox-LDL-induced endothelial apoptosis via Ets-1/p21 inhibition

(2015) Bing Qin et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

SOCS3 in retinal neurons and glial cells suppresses VEGF signaling to prevent pathological neovascular growth

(2015) Ye Sun et al.   Science Signaling

MiR-221/222 promote human glioma cell invasion and angiogenesis by targeting TIMP2

(2015) Fan Yang et al.   TUMOR BIOLOGY

SOCS3 in retinal neurons and glial cells suppresses VEGF signaling to prevent pathological neovascular growth

(2015) Ye Sun et al.   Science Signaling

Survival in Patients with High-Risk Prostate Cancer Is Predicted by miR-221, Which Regulates Proliferation, Apoptosis, and Invasion of Prostate Cancer Cells by Inhibiting IRF2 and SOCS3

(2014) B. Kneitz et al.   CANCER RESEARCH

Levels of vascular endothelial growth factor and matrix metalloproteinase-9 proteins in patients with glioma

(2014) Chengyuan Ma et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Concise Review: MicroRNAs as Modulators of Stem Cells and Angiogenesis

(2014) Nicole M. Kane et al.   STEM CELLS

STAT3 Activation in Glioblastoma: Biochemical and Therapeutic Implications

(2014) Jennifer Kim et al.   Cancers

EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis

(2013) Krishna M. Talasila et al.   ACTA NEUROPATHOLOGICA

Elevated expression of tumor miR-222 in pancreatic cancer is associated with Ki67 and poor prognosis

(2013) ChongLek Lee et al.   MEDICAL ONCOLOGY

Prognostic value of vascular endothelial growth factor A expression in gastric cancer: a meta-analysis

(2013) Ya-nan Ji et al.   TUMOR BIOLOGY

SOCS3 is an endogenous inhibitor of pathologic angiogenesis

(2012) A. Stahl et al.   BLOOD

Myc-associated zinc finger protein (MAZ) is regulated by miR-125b and mediates VEGF-induced angiogenesis in glioblastoma

(2012) Michiel Smits et al.   FASEB JOURNAL

Suppressor of Cytokine Signaling 3 Inhibits Breast Tumor Kinase Activation of STAT3

(2012) Yiwei Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SOCS3 promoter methylation is mutually exclusive to EGFR amplification in gliomas and promotes glioma cell invasion through STAT3 and FAK activation

(2011) Carina Lindemann et al.   ACTA NEUROPATHOLOGICA

A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma

(2011) Ashwatha Narayana et al.   JOURNAL OF NEUROSURGERY

JAK2/STAT3 signaling pathway activation mediates tumor angiogenesis by upregulation of VEGF and bFGF in non-small-cell lung cancer

(2011) Mei Zhao et al.   LUNG CANCER

Inhibition of the JAK-2/STAT3 signaling pathway impedes the migratory and invasive potential of human glioblastoma cells

(2010) Christian Senft et al.   JOURNAL OF NEURO-ONCOLOGY

Prognostic relevance of SOCS3 hypermethylation in patients with glioblastoma multiforme

(2008) Maurizio Martini et al.   INTERNATIONAL JOURNAL OF CANCER

The hemopexin domain of MMP-9 inhibits angiogenesis and retards the growth of intracranial glioblastoma xenograft in nude mice

(2008) Ravesanker Ezhilarasan et al.   INTERNATIONAL JOURNAL OF CANCER