STAT3 is essential for the maintenance of neurosphere-initiating tumor cells in patients with glioblastomas: A potential for targeted therapy?

JSI-124 inhibits glioblastoma multiforme cell proliferation through G2/M cell cycle arrest and apoptosis augmentation

(2010) Yuhang Su et al.   CANCER BIOLOGY & THERAPY

LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model

(2009) B Fuh et al.   BRITISH JOURNAL OF CANCER

Stat3 activation is required for the growth of U87 cell-derived tumours in mice

(2009) Atreyi Dasgupta et al.   EUROPEAN JOURNAL OF CANCER

Mitochondrial STAT3 Supports Ras-Dependent Oncogenic Transformation

(2009) D. J. Gough et al.   SCIENCE

Function of Mitochondrial Stat3 in Cellular Respiration

(2009) J. Wegrzyn et al.   SCIENCE

STAT3 Is Required for Proliferation and Maintenance of Multipotency in Glioblastoma Stem Cells

(2009) Maureen M. Sherry et al.   STEM CELLS

Temozolomide Preferentially Depletes Cancer Stem Cells in Glioblastoma

(2008) D. Beier et al.   CANCER RESEARCH

Constitutively Activated STAT3 Frequently Coexpresses with Epidermal Growth Factor Receptor in High-Grade Gliomas and Targeting STAT3 Sensitizes Them to Iressa and Alkylators

(2008) H.-W. Lo et al.   CLINICAL CANCER RESEARCH

Loss of Protein Inhibitors of Activated STAT-3 Expression in Glioblastoma Multiforme Tumors: Implications for STAT-3 Activation and Gene Expression

(2008) E. C. Brantley et al.   CLINICAL CANCER RESEARCH

The Incidence, Correlation with Tumor-Infiltrating Inflammation, and Prognosis of Phosphorylated STAT3 Expression in Human Gliomas

(2008) M. Abou-Ghazal et al.   CLINICAL CANCER RESEARCH

Unphosphorylated STATs go nuclear

(2008) Stephen Brown et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Modulatory Effects of Polyphenols on Apoptosis Induction: Relevance for Cancer Prevention

(2008) Massimo D’Archivio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Blockage of the STAT3 signaling pathway with a decoy oligonucleotide suppresses growth of human malignant glioma cells

(2008) Jinhai Gu et al.   JOURNAL OF NEURO-ONCOLOGY

STAT3 silencing with lentivirus inhibits growth and induces apoptosis and differentiation of U251 cells

(2008) Guang-hui Li et al.   JOURNAL OF NEURO-ONCOLOGY

Combined Targeting of Epidermal Growth Factor Receptor, Signal Transducer and Activator of Transcription-3, and Bcl-XL Enhances Antitumor Effects in Squamous Cell Carcinoma of the Head and Neck

(2008) A. L. Boehm et al.   MOLECULAR PHARMACOLOGY

Efficient tumour formation by single human melanoma cells

(2008) Elsa Quintana et al.   NATURE

IDENTIFICATION OF A2B5+CD133− TUMOR-INITIATING CELLS IN ADULT HUMAN GLIOMAS

(2008) Alfred T. Ogden et al.   NEUROSURGERY

Wnt-mediated self-renewal of neural stem/progenitor cells

(2008) M. Y. S. Kalani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Don't Look: Growing Clonal Versus Nonclonal Neural Stem Cell Colonies

(2008) Brenda L.K. Coles-Takabe et al.   STEM CELLS