Therapeutic Targeting of Stat3 Using Lipopolyplex Nanoparticle-Formulated siRNA in a Syngeneic Orthotopic Mouse Glioma Model
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Title
Therapeutic Targeting of Stat3 Using Lipopolyplex Nanoparticle-Formulated siRNA in a Syngeneic Orthotopic Mouse Glioma Model
Authors
Keywords
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Journal
Cancers
Volume 11, Issue 3, Pages 333
Publisher
MDPI AG
Online
2019-03-09
DOI
10.3390/cancers11030333
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Note: Only part of the references are listed.- STAT3, stem cells, cancer stem cells and p63
- (2018) Michaela Galoczova et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- First-in-human evaluation of the Cleveland Multiport Catheter for convection-enhanced delivery of topotecan in recurrent high-grade glioma: results of pilot trial 1
- (2018) Michael A. Vogelbaum et al. JOURNAL OF NEUROSURGERY
- Nanoparticle/siRNA-based therapy strategies in glioma: which nanoparticles, which siRNAs?
- (2018) Achim Aigner et al. Nanomedicine
- Systematic analysis of protein turnover in primary cells
- (2018) Toby Mathieson et al. Nature Communications
- The critical role that STAT3 plays in glioma-initiating cells: STAT3 addiction in glioma
- (2018) Debolina Ganguly et al. Oncotarget
- STAT3 Gene Silencing by Aptamer-siRNA Chimera as Selective Therapeutic for Glioblastoma
- (2018) Carla Lucia Esposito et al. Molecular Therapy-Nucleic Acids
- Tumor tissue slice cultures as a platform for analyzing tissue-penetration and biological activities of nanoparticles
- (2017) Lea Merz et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Liposome-polyethylenimine complexes (DPPC-PEI lipopolyplexes) for therapeutic siRNA delivery in vivo
- (2017) Alexander Ewe et al. Nanomedicine-Nanotechnology Biology and Medicine
- Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression
- (2017) Dou Yu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Polyethylenimine Nanoparticle-Mediated siRNA Delivery to Reduce α-Synuclein Expression in a Model of Parkinson’s Disease
- (2017) Christin Helmschrodt et al. Molecular Therapy-Nucleic Acids
- Intranasal drug delivery of small interfering RNA targeting Beclin1 encapsulated with polyethylenimine (PEI) in mouse brain to achieve HIV attenuation
- (2017) Myosotys Rodriguez et al. Scientific Reports
- Microparticulate poly(vinyl alcohol) hydrogel formulations for embedding and controlled release of polyethylenimine (PEI)-based nanoparticles
- (2016) Jan Schulze et al. Acta Biomaterialia
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- Protein stabilization improves STAT3 function in autosomal dominant hyper-IgE syndrome
- (2016) C. E. Bocchini et al. BLOOD
- Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma
- (2016) Michele Ceccarelli et al. CELL
- Interference with the HSF1/HSP70/BAG3 Pathway Primes Glioma Cells to Matrix Detachment and BH3 Mimetic–Induced Apoptosis
- (2016) Patrick Antonietti et al. MOLECULAR CANCER THERAPEUTICS
- GlioVis data portal for visualization and analysis of brain tumor expression datasets
- (2016) Robert L. Bowman et al. NEURO-ONCOLOGY
- Correction: Stat3 Activation Is Responsible for IL-6–Dependent T Cell Proliferation through Preventing Apoptosis: Generation and Characterization of T Cell–Specific Stat3-Deficient Mice
- (2015) Kiyoshi Takeda et al. JOURNAL OF IMMUNOLOGY
- RNA interference targeting hypoxia-inducible factor 1α via a novel multifunctional surfactant attenuates glioma growth in an intracranial mouse model
- (2015) David L. Gillespie et al. JOURNAL OF NEUROSURGERY
- Mesenchymal Stem Cells Isolated From Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL-6/gp130/STAT3 Pathway
- (2015) Anwar Hossain et al. STEM CELLS
- Sorafenib Sensitizes Glioma Cells to the BH3 Mimetic ABT-737 by Targeting MCL1 in a STAT3-Dependent Manner
- (2015) Irina Kiprianova et al. NEOPLASIA
- Storage stability of optimal liposome–polyethylenimine complexes (lipopolyplexes) for DNA or siRNA delivery
- (2014) Alexander Ewe et al. Acta Biomaterialia
- Nebulization of liposome-polyethylenimine complexes (lipopolyplexes) for DNA or siRNA delivery: Physicochemical properties and biological activity
- (2014) Alexander Ewe et al. EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY
- STAT3 Activation in Glioblastoma: Biochemical and Therapeutic Implications
- (2014) Jennifer Kim et al. Cancers
- Depletion of the transcriptional coactivators megakaryoblastic leukaemia 1 and 2 abolishes hepatocellular carcinoma xenograft growth by inducing oncogene-induced senescence
- (2013) Veronika Hampl et al. EMBO Molecular Medicine
- Using the molecular classification of glioblastoma to inform personalized treatment
- (2013) Adriana Olar et al. JOURNAL OF PATHOLOGY
- STAT3 silencing inhibits glioma single cell infiltration and tumor growth
- (2013) M. Priester et al. NEURO-ONCOLOGY
- Polyethylenimines for siRNA and miRNA delivery in vivo
- (2013) Sabrina Höbel et al. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
- STAT3 as a Therapeutic Target for Glioblastoma
- (2012) Yan Liu et al. Anti-Cancer Agents in Medicinal Chemistry
- Status Quo—Standard-of-Care Medical and Radiation Therapy for Glioblastoma
- (2012) Kevin P. Becker et al. CANCER JOURNAL
- Signal transducer and activator of transcription 3 promotes angiogenesis and drives malignant progression in glioma
- (2012) Tiffany A. Doucette et al. NEURO-ONCOLOGY
- On-target JAK2/STAT3 inhibition slows disease progression in orthotopic xenografts of human glioblastoma brain tumor stem cells
- (2012) Owen D. Stechishin et al. NEURO-ONCOLOGY
- The molecular profile of microglia under the influence of glioma
- (2012) W. Li et al. NEURO-ONCOLOGY
- Comparing routes of delivery for nanoliposomal irinotecan shows superior anti-tumor activity of local administration in treating intracranial glioblastoma xenografts
- (2012) Pin-Yuan Chen et al. NEURO-ONCOLOGY
- Targeting Stat3 and Smad7 to restore TGF-β cytostatic regulation of tumor cells in vitro and in vivo
- (2012) R B Luwor et al. ONCOGENE
- MicroRNA Replacement Therapy for miR-145 and miR-33a Is Efficacious in a Model of Colon Carcinoma
- (2011) A. F. Ibrahim et al. CANCER RESEARCH
- The Antisense Oligonucleotide Trabedersen (AP 12009) for the Targeted Inhibition of TGF-β2
- (2011) Frank Jaschinski et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- A Quantitative Spatial Proteomics Analysis of Proteome Turnover in Human Cells
- (2011) François-Michel Boisvert et al. MOLECULAR & CELLULAR PROTEOMICS
- RNA interference targeting survivin exerts antitumoral effects in vitro and in established glioma xenografts in vivo
- (2011) S. Hendruschk et al. NEURO-ONCOLOGY
- Regression of Recurrent Malignant Gliomas With Convection-Enhanced Delivery of Topotecan
- (2011) Jeffrey N. Bruce et al. NEUROSURGERY
- Liposome–polyethylenimine complexes for enhanced DNA and siRNA delivery
- (2010) Jens Schäfer et al. BIOMATERIALS
- Induction of in vivo synthetic lethal RNAi responses to treat glioblastoma
- (2010) Hiroyuki Michiue et al. CANCER BIOLOGY & THERAPY
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
- Dietary Curcumin Attenuates Glioma Growth in a Syngeneic Mouse Model by Inhibition of the JAK1,2/STAT3 Signaling Pathway
- (2010) J. Weissenberger et al. CLINICAL CANCER RESEARCH
- Inhibition of the JAK-2/STAT3 signaling pathway impedes the migratory and invasive potential of human glioblastoma cells
- (2010) Christian Senft et al. JOURNAL OF NEURO-ONCOLOGY
- Cancer Metastasis Is Accelerated through Immunosuppression during Snail-Induced EMT of Cancer Cells
- (2009) Chie Kudo-Saito et al. CANCER CELL
- Stat3 activation is required for the growth of U87 cell-derived tumours in mice
- (2009) Atreyi Dasgupta et al. EUROPEAN JOURNAL OF CANCER
- Highly efficient eradication of intracranial glioblastoma using Eg5 siRNA combined with HVJ envelope
- (2009) M Matsuda et al. GENE THERAPY
- The transcriptional network for mesenchymal transformation of brain tumours
- (2009) Maria Stella Carro et al. NATURE
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- (2009) Maureen M. Sherry et al. STEM CELLS
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- (2008) Young Tag Ko et al. JOURNAL OF CONTROLLED RELEASE
- Signal Transducer and Activator of Transcription-3: A Molecular Hub for Signaling Pathways in Gliomas
- (2008) E. C. Brantley et al. MOLECULAR CANCER RESEARCH
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
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