Sulforaphane suppresses the growth of glioblastoma cells, glioblastoma stem cell–like spheroids, and tumor xenografts through multiple cell signaling pathways

Dietary Sulforaphane in Cancer Chemoprevention: The Role of Epigenetic Regulation and HDAC Inhibition

(2015) Stephanie M. Tortorella et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial energy metabolism and apoptosis regulation in glioblastoma

(2015) Adam Nagy et al.   BRAIN RESEARCH

Hypoxia Is the Driving Force Behind GBM and Could Be a New Tool in GBM Treatment

(2015) Rasime Kalkan   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

How to train glioma cells to die: molecular challenges in cell death

(2015) Jeffrey Wojton et al.   JOURNAL OF NEURO-ONCOLOGY

miR-144-3p exerts anti-tumor effects in glioblastoma by targeting c-Met

(2015) Fengming Lan et al.   JOURNAL OF NEUROCHEMISTRY

Stem cell signature in glioblastoma: therapeutic development for a moving target

(2015) Ichiro Nakano   JOURNAL OF NEUROSURGERY

Isothiocyanates inhibit the invasion and migration of C6 glioma cells by blocking FAK/JNK-mediated MMP-9 expression

(2015) CHANG-SU LEE et al.   ONCOLOGY REPORTS

Reactive oxygen species-mediated therapeutic response and resistance in glioblastoma

(2015) E Singer et al.   Cell Death & Disease

Cytotoxic and Antitumor Activity of Sulforaphane: The Role of Reactive Oxygen Species

(2015) Piero Sestili et al.   Biomed Research International

Glioblastoma stem-like cells: at the root of tumor recurrence and a therapeutic target

(2014) Melanie Jackson et al.   CARCINOGENESIS

The Transcription Factor Nrf2 Is a Therapeutic Target against Brain Inflammation

(2014) N. G. Innamorato et al.   JOURNAL OF IMMUNOLOGY

Sulforaphane Induces DNA Damage and Mitotic Abnormalities in Human Osteosarcoma MG-63 Cells: Correlation with Cell Cycle Arrest and Apoptosis

(2014) José Miguel P. Ferreira de Oliveira et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Stem Cell Niches in Glioblastoma: A Neuropathological View

(2014) Davide Schiffer et al.   Biomed Research International

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates

(2013) Praveen Rajendran et al.   Epigenetics

Modulation of mitochondrial functions by the indirect antioxidant sulforaphane: A seemingly contradictory dual role and an integrative hypothesis

(2013) Mario Negrette-Guzmán et al.   FREE RADICAL BIOLOGY AND MEDICINE

Targeting cancer stem cells with sulforaphane, a dietary component from broccoli and broccoli sprouts

(2013) Yanyan Li et al.   Future Oncology

CD133 Is Essential for Glioblastoma Stem Cell Maintenance

(2013) Paola Brescia et al.   STEM CELLS

Wnt/β-catenin signaling is a key downstream mediator of MET signaling in glioblastoma stem cells

(2012) Kang Ho Kim et al.   NEURO-ONCOLOGY

Bioactive Dietary Supplements Reactivate ER Expression in ER-Negative Breast Cancer Cells by Active Chromatin Modifications

(2012) Syed M. Meeran et al.   PLoS One

Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity

(2011) Vittorio Calabrese et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Sulforaphane induces apoptosis in human hepatic cancer cells through inhibition of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase4, mediated by hypoxia inducible factor-1-dependent pathway

(2011) Young Keul Jeon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Deadly Teamwork: Neural Cancer Stem Cells and the Tumor Microenvironment

(2011) Justin D. Lathia et al.   Cell Stem Cell

Sulforaphane protects brains against hypoxic–ischemic injury through induction of Nrf2-dependent phase 2 enzyme

(2010) Zhang Ping et al.   BRAIN RESEARCH

Anti-carcinogenic effects of sulforaphane in association with its apoptosis-inducing and anti-inflammatory properties in human cervical cancer cells

(2010) Chhavi Sharma et al.   Cancer Epidemiology

4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide (CMH) targets mRNA of the c-FLIP variants and induces apoptosis in MCF-7 human breast cancer cells

(2010) Khadijeh Bijangi-Vishehsaraei et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics

(2010) Camilla Krakstad et al.   Molecular Cancer

Sulforaphane induces DNA single strand breaks in cultured human cells

(2010) Piero Sestili et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Sulforaphane induces DNA double strand breaks predominantly repaired by homologous recombination pathway in human cancer cells

(2008) Emiko Sekine-Suzuki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sulforaphane Enhances the Therapeutic Potential of TRAIL in Prostate Cancer Orthotopic Model through Regulation of Apoptosis, Metastasis, and Angiogenesis

(2008) S. Shankar et al.   CLINICAL CANCER RESEARCH

Sulforaphane enhances caspase-dependent apoptosis through inhibition of cyclooxygenase-2 expression in human oral squamous carcinoma cells and nude mouse xenograft model

(2008) Nam-Pyo Cho et al.   ORAL ONCOLOGY