Mitochondrial dysfunction in nonalcoholic steatohepatitis

The role of mitochondria in apoptosis

(2011) Seon-Yong Jeong et al.   BMB Reports

Signaling and cytotoxic functions of 4-hydroxyalkenals

(2010) Yael Riahi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Animal and human studies with the mitochondria-targeted antioxidant MitoQ

(2010) Robin A.J. Smith et al.   Annals of the New York Academy of Sciences

Signaling Functions of Reactive Oxygen Species

(2010) Henry Jay Forman et al.   BIOCHEMISTRY

Targeting Mitochondria: A New Promising Approach for the Treatment of Liver Diseases

(2010) G. Serviddio et al.   CURRENT MEDICINAL CHEMISTRY

Therapeutic trials in nonalcoholic steatohepatitis: Insulin sensitizers and related methodological issues

(2010) Vlad Ratziu et al.   HEPATOLOGY

Effects of a high fat diet on liver mitochondria: increased ATP-sensitive K+ channel activity and reactive oxygen species generation

(2010) Ariel R. Cardoso et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Impact of pan-caspase inhibition in animal models of established steatosis and non-alcoholic steatohepatitis

(2010) Quentin M. Anstee et al.   JOURNAL OF HEPATOLOGY

Down-regulation of SREBP-1c is associated with the development of burned-out NASH

(2010) Tadanobu Nagaya et al.   JOURNAL OF HEPATOLOGY

Autophagy and the degradation of mitochondria

(2010) Scott J. Goldman et al.   MITOCHONDRION

A Complex Role of Activin A in Non-Alcoholic Fatty Liver Disease

(2009) Arne Yndestad et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Modulation of the hepatic malonyl-CoA–carnitine palmitoyltransferase 1A partnership creates a metabolic switch allowing oxidation ofde novofatty acids1

(2009) Marie Akkaoui et al.   BIOCHEMICAL JOURNAL

Transport of proteins across or into the mitochondrial outer membrane

(2009) Toshiya Endo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

UCP3 Expression in Liver Modulates Gene Expression and Oxidative Metabolism in Response to Fatty Acids, and Sensitizes Mitochondria to Permeability Transition

(2009) Yolanda Camara et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Curcumin ameliorates rabbits's steatohepatitis via respiratory chain, oxidative stress, and TNF-α

(2009) M. Carmen Ramirez-Tortosa et al.   FREE RADICAL BIOLOGY AND MEDICINE

Intramitochondrial crystalline inclusions in nonalcoholic steatohepatitis

(2009) Stephen H. Caldwell et al.   HEPATOLOGY

Palmitate Induces Insulin Resistance in H4IIEC3 Hepatocytes through Reactive Oxygen Species Produced by Mitochondria

(2009) Seiji Nakamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Absence of Nitric-oxide Synthase in Sequentially Purified Rat Liver Mitochondria

(2009) Priya Venkatakrishnan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apoptosis in experimental NASH is associated with p53 activation and TRAIL receptor expression

(2009) Geoffrey C Farrell et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Electron microscopic findings in non-alcoholic fatty liver disease: Is there a difference between hepatosteatosis and steatohepatitis?

(2009) Emel Ahishali et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

A Silybin-Phospholipid Complex Prevents Mitochondrial Dysfunction in a Rodent Model of Nonalcoholic Steatohepatitis

(2009) G. Serviddio et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Cell Death

(2009) Richard S. Hotchkiss et al.   NEW ENGLAND JOURNAL OF MEDICINE

A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels

(2008) Maja Stefanovic-Racic et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial functionin vivo

(2008) Sudheer K. Mantena et al.   BIOCHEMICAL JOURNAL

Fatty liver and insulin resistance in obese Zucker rats: No role for mitochondrial dysfunction

(2008) Mélissa Flamment et al.   BIOCHIMIE

L-Carnitine suppresses oleic acid-induced membrane permeability transition of mitochondria

(2008) Eri Oyanagi et al.   CELL BIOCHEMISTRY AND FUNCTION

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism

Alterations of hepatic ATP homeostasis and respiratory chain during development of non-alcoholic steatohepatitis in a rodent model

(2008) G. Serviddio et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Cellular and Molecular Mechanisms of Liver Injury

(2008) Harmeet Malhi et al.   GASTROENTEROLOGY

Uncoupling protein-2 (UCP2) induces mitochondrial proton leak and increases susceptibility of non-alcoholic steatohepatitis (NASH) liver to ischaemia-reperfusion injury

(2008) G Serviddio et al.   GUT

The mitochondrial gateway to cell death

(2008) Danielle J. Smith et al.   IUBMB LIFE

Alleviation of ischemia/reperfusion injury in ob/ob mice by inhibiting UCP-2 expression in fatty liver

(2008) Chi-Dan Wan et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Mitochondrial adaptations to steatohepatitis induced by a methionine- and choline-deficient diet

(2007) Caroline Romestaing et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM