Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver

Reduced mitochondrial function in obesity-associated fatty liver: SIRT3 takes on the fat

(2016) Mahua Choudhury et al.   Aging-US

FGF15/19 Regulates Hepatic Glucose Metabolism by Inhibiting the CREB-PGC-1α Pathway

(2011) Matthew J. Potthoff et al.   Cell Metabolism

Excessive Hepatic Mitochondrial TCA Cycle and Gluconeogenesis in Humans with Nonalcoholic Fatty Liver Disease

(2011) Nishanth E. Sunny et al.   Cell Metabolism

Oxidative Phosphorylation Flexibility in the Liver of Mice Resistant to High-Fat Diet-Induced Hepatic Steatosis

(2011) C. Poussin et al.   DIABETES

The role of mitochondria in insulin resistance and type 2 diabetes mellitus

(2011) Julia Szendroedi et al.   Nature Reviews Endocrinology

Progressive adaptation of hepatic ketogenesis in mice fed a high-fat diet

(2010) Nishanth E. Sunny et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Targeting Forkhead Box O1 from the Concept to Metabolic Diseases: Lessons from Mouse Models

(2010) Zhiyong Cheng et al.   ANTIOXIDANTS & REDOX SIGNALING

Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation

(2010) Agnieszka A. Kendrick et al.   BIOCHEMICAL JOURNAL

The Effects of Palmitate on Hepatic Insulin Resistance Are Mediated by NADPH Oxidase 3-derived Reactive Oxygen Species through JNK and p38MAPKPathways

(2010) Dan Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Mitochondrial Oxidative Phosphorylation in the Liver Is Associated With Obesity and Insulin Resistance

(2010) David A. Buchner et al.   Obesity

Role of Insulin Resistance and Lipotoxicity in Non-Alcoholic Steatohepatitis

(2009) Kenneth Cusi   Clinics in Liver Disease

Depletion of Liver Kupffer Cells Prevents the Development of Diet-Induced Hepatic Steatosis and Insulin Resistance

(2009) W. Huang et al.   DIABETES

Intramitochondrial crystalline inclusions in nonalcoholic steatohepatitis

(2009) Stephen H. Caldwell et al.   HEPATOLOGY

Abnormal hepatic energy homeostasis in type 2 diabetes

(2009) Julia Szendroedi et al.   HEPATOLOGY

Effect of Anaplerotic Fluxes and Amino Acid Availability on Hepatic Lipoapoptosis

(2009) Yasushi Noguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Palmitate Induces Insulin Resistance in H4IIEC3 Hepatocytes through Reactive Oxygen Species Produced by Mitochondria

(2009) Seiji Nakamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Foxo1 integrates insulin signaling with mitochondrial function in the liver

(2009) Zhiyong Cheng et al.   NATURE MEDICINE

Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes

(2009) V. T. Samuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial functionin vivo

(2008) Sudheer K. Mantena et al.   BIOCHEMICAL JOURNAL

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism

Partial Resistance to Peroxisome Proliferator-Activated Receptor-  Agonists in ZDF Rats Is Associated With Defective Hepatic Mitochondrial Metabolism

(2008) S. Satapati et al.   DIABETES

Adipose tissue fatty acid metabolism in insulin-resistant men

(2008) A. S. T. Bickerton et al.   DIABETOLOGIA

Uncoupling protein-2 (UCP2) induces mitochondrial proton leak and increases susceptibility of non-alcoholic steatohepatitis (NASH) liver to ischaemia-reperfusion injury

(2008) G Serviddio et al.   GUT

Alterations in hepatic glucose and energy metabolism as a result of calorie and carbohydrate restriction

(2008) Jeffrey D. Browning et al.   HEPATOLOGY

Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes

(2008) Deborah M. Muoio et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sequential Responses to High-fat and High-calorie Feeding in an Obese Mouse Model

(2008) Mei-Yen Chan et al.   Obesity

Obesity Upregulates Genes Involved in Oxidative Phosphorylation in Livers of Diabetic Patients

(2008) Toshinari Takamura et al.   Obesity

The role of FoxO in the regulation of metabolism

(2008) D N Gross et al.   ONCOGENE