JNK interaction with Sab mediates ER stress induced inhibition of mitochondrial respiration and cell death

Mitochondrial Dysfunction Indirectly Elevates ROS Production by the Endoplasmic Reticulum

(2013) Michael P. Murphy   Cell Metabolism

Regulation of drug-induced liver injury by signal transduction pathways: critical role of mitochondria

(2013) Derick Han et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Hepatic mitochondrial dysfunction induced by fatty acids and ethanol

(2012) Daniel Gyamfi et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Liver Full of JNK: Signaling in Regulation of Cell Function and Disease Pathogenesis, and Clinical Approaches

(2012) Ekihiro Seki et al.   GASTROENTEROLOGY

Blocking c-Jun N-terminal Kinase (JNK) Translocation to the Mitochondria Prevents 6-Hydroxydopamine-induced Toxicityin Vitroandin Vivo

(2012) Jeremy W. Chambers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of JNK Mitochondrial Localization and Signaling Is Protective against Ischemia/Reperfusion Injury in Rats

(2012) Jeremy W. Chambers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bax Inhibitor-1 is a novel IP3 receptor-interacting and -sensitizing protein

(2012) S Kiviluoto et al.   Cell Death & Disease

Selective Inhibition of Mitochondrial JNK Signaling Achieved Using Peptide Mimicry of the Sab Kinase Interacting Motif-1 (KIM1)

(2011) Jeremy W. Chambers et al.   ACS Chemical Biology

Ero1α Regulates Ca2+ Fluxes at the Endoplasmic Reticulum–Mitochondria Interface (MAM)

(2011) Tiziana Anelli et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of brefeldin A-induced ER stress and apoptosis by mitochondrial NADP+-dependent isocitrate dehydrogenase

(2011) Jung Lee Moon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1–JNK pathway

(2011) H Kato et al.   CELL DEATH AND DIFFERENTIATION

The sarcoplasmic reticulum luminal thiol oxidase ERO1 regulates cardiomyocyte excitation-coupled calcium release and response to hemodynamic load

(2011) King-Tung Chin et al.   FASEB JOURNAL

Role of cAMP-responsive Element-binding Protein (CREB)-regulated Transcription Coactivator 3 (CRTC3) in the Initiation of Mitochondrial Biogenesis and Stress Response in Liver Cells

(2011) Tin Aung Than et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

c-Jun N-terminal Kinase (JNK)-dependent Acute Liver Injury from Acetaminophen or Tumor Necrosis Factor (TNF) Requires Mitochondrial Sab Protein Expression in Mice

(2011) Sanda Win et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial c-Jun N-terminal Kinase (JNK) Signaling Initiates Physiological Changes Resulting in Amplification of Reactive Oxygen Species Generation

(2011) Jeremy W. Chambers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

The Regulation and Physiology of Mitochondrial Proton Leak

(2011) Ajit S. Divakaruni et al.   PHYSIOLOGY

An intimate liaison: spatial organization of the endoplasmic reticulum–mitochondria relationship

(2010) Olga Martins de Brito et al.   EMBO JOURNAL

Role of ERO1-α–mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress–induced apoptosis

(2009) Gang Li et al.   JOURNAL OF CELL BIOLOGY

Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways

(2009) Jenelle M. Timmins et al.   JOURNAL OF CLINICAL INVESTIGATION

High- and low-calcium-dependent mechanisms of mitochondrial calcium signalling

(2008) A SPAT et al.   CELL CALCIUM

Bcl-2 suppresses Ca2+ release through inositol 1,4,5-trisphosphate receptors and inhibits Ca2+ uptake by mitochondria without affecting ER calcium store content

(2008) C. Jane Hanson et al.   CELL CALCIUM

Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition

(2008) Magnus J. Hansson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of JNK Translocation to Mitochondria Leading to Inhibition of Mitochondria Bioenergetics in Acetaminophen-induced Liver Injury

(2008) Naoko Hanawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY