Crystal Structure of NALP3 Protein Pyrin Domain (PYD) and Its Implications in Inflammasome Assembly

Structural analyses of death domains and their interactions

(2011) Hyun Ho Park   APOPTOSIS

Generalized semi-refolding methods for purification of the functional death domain superfamily

(2011) Tae-ho Jang et al.   JOURNAL OF BIOTECHNOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Three-dimensional Structure of the NLRP7 Pyrin Domain

(2010) Anderson S. Pinheiro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Fas–FADD death domain complex structure reveals the basis of DISC assembly and disease mutations

(2010) Liwei Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Innate instruction of adaptive immunity revisited: the inflammasome

(2009) Stephanie C. Eisenbarth et al.   EMBO Molecular Medicine

Expression and function of the NALP3 inflammasome in rheumatoid synovium

(2009) Laeticia Kolly et al.   IMMUNOLOGY

Intracellular innate immunity in gouty arthritis: role of NALP3 inflammasome

(2009) Ru Liu-Bryan   IMMUNOLOGY AND CELL BIOLOGY

Structure and Interdomain Dynamics of Apoptosis-associated Speck-like Protein Containing a CARD (ASC)

(2009) Eva de Alba   JOURNAL OF BIOLOGICAL CHEMISTRY

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

(2009) Teresa Fernandes-Alnemri et al.   NATURE

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

Monomer/Dimer Transition of the Caspase-Recruitment Domain of Human Nod1†,‡

(2008) Thiagarajan Srimathi et al.   BIOCHEMISTRY

Mapping of POP1-binding Site on Pyrin Domain of ASC

(2008) Thiagarajan Srimathi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE