Regulation of NF-B-Induced Inflammatory Signaling by Lipid Peroxidation-Derived Aldehydes

Oxidative Stress Treatment for Clinical Trials in Neurodegenerative Diseases

(2018) Elena Caldarazzo Ienco et al.   JOURNAL OF ALZHEIMERS DISEASE

Role of By-Products of Lipid Oxidation in Alzheimer's Disease Brain: A Focus on Acrolein

(2017) Manjeet Singh et al.   JOURNAL OF ALZHEIMERS DISEASE

Cell signalling by reactive lipid species: new concepts and molecular mechanisms

(2012) Ashlee Higdon et al.   BIOCHEMICAL JOURNAL

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

Modulation of the oxidative stress and inflammatory cytokine response by thymoquinone in the collagen induced arthritis in Wistar rats

(2012) Sadiq Umar et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The effect of environmental oxidative stress on airway inflammation

(2012) Amy Auerbach et al.   Current Opinion in Allergy and Clinical Immunology

The Lipid Peroxidation By-Product 4-Hydroxy-2-Nonenal (4-HNE) Induces Insulin Resistance in Skeletal Muscle through Both Carbonyl and Oxidative Stress

(2012) Nicolas J. Pillon et al.   ENDOCRINOLOGY

Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders

(2011) Satish K. Srivastava et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Emerging Role of Antioxidants in the Protection of Uveitis Complications

(2011) U. C.S. Yadav et al.   CURRENT MEDICINAL CHEMISTRY

Clinical trials of antioxidants as cancer prevention agents: Past, present, and future

(2011) Michael Goodman et al.   FREE RADICAL BIOLOGY AND MEDICINE

Divergent behaviour of oxidative stress markers 8-hydroxydeoxyguanosine (8-OHdG) and 4-hydroxy-2-nonenal (HNE) in breast carcinogenesis

(2011) Peeter Karihtala et al.   HISTOPATHOLOGY

Hepatotoxicity and Nephrotoxicity Produced by 4-Hydroxy-2-Nonenal (4-HNE) Following 4-Week Oral Administration to Sprague-Dawley Rats

(2011) Se Chan Kang et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

The balance between 4-hydroxynonenal and intrinsic glutathione/glutathione S-transferase A4 system may be critical for the epidermal growth factor receptor phosphorylation of human esophageal squamous cell carcinomas

(2011) Kaname Uno et al.   MOLECULAR CARCINOGENESIS

Systems Analysis of Protein Modification and Cellular Responses Induced by Electrophile Stress

(2010) Aaron T. Jacobs et al.   ACCOUNTS OF CHEMICAL RESEARCH

Reactive oxygen species and α,β-unsaturated aldehydes as second messengers in signal transduction

(2010) Henry Jay Forman   Annals of the New York Academy of Sciences

Mechanisms of 4-Hydroxy-2-nonenal Induced Pro- and Anti-Apoptotic Signaling

(2010) Pankaj Chaudhary et al.   BIOCHEMISTRY

Signaling Functions of Reactive Oxygen Species

(2010) Henry Jay Forman et al.   BIOCHEMISTRY

Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease☆

(2010) D. Allan Butterfield et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Antioxidant Micronutrients and Biomarkers of Oxidative Stress and Inflammation in Colorectal Adenoma Patients: Results from a Randomized, Controlled Clinical Trial

(2010) M. H. Hopkins et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

HNE-induced 5-LO expression is regulated by NF- B/ERK and Sp1/p38 MAPK pathways via EGF receptor in murine macrophages

(2010) S. J. Lee et al.   CARDIOVASCULAR RESEARCH

Differential roles of AMPKα1 and AMPKα2 in regulating 4-HNE-induced RPE cell death and permeability

(2010) Suofu Qin et al.   EXPERIMENTAL EYE RESEARCH

Role of 4-hydroxynonenal in epidermal growth factor receptor-mediated signaling in retinal pigment epithelial cells

(2010) Rit Vatsyayan et al.   EXPERIMENTAL EYE RESEARCH

N-acetylcysteine protects alveolar epithelial cells from hydrogen peroxide–induced apoptosis through scavenging reactive oxygen species and suppressing c-Jun N-terminalkinase

(2010) Yue-qiang Fu et al.   EXPERIMENTAL LUNG RESEARCH

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

4-hydroxy-2-nonenal upregulates and phosphorylates cytosolic phospholipase A2 in cultured Ra2 microglial cells via MAPK pathways

(2010) Noriyuki Shibata et al.   NEUROPATHOLOGY

Glutathione dysregulation and the etiology and progression of human diseases

(2009) Nazzareno Ballatori et al.   BIOLOGICAL CHEMISTRY

Molecular Mechanisms of 4-Hydroxy-2-nonenal and Acrolein Toxicity: Nucleophilic Targets and Adduct Formation

(2009) Richard M. LoPachin et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Acrolein induces a cellular stress response and triggers mitochondrial apoptosis in A549 cells

(2009) Julie Roy et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Roles of the lipid peroxidation product 4-hydroxynonenal in obesity, the metabolic syndrome, and associated vascular and neurodegenerative disorders

(2009) Mark P. Mattson   EXPERIMENTAL GERONTOLOGY

Peptides as antioxidants and carbonyl quenchers in biological model systems

(2009) Sisse Jongberg et al.   FREE RADICAL RESEARCH

4-Hydroxynonenal enhances MMP-9 production in murine macrophages via 5-lipoxygenase-mediated activation of ERK and p38 MAPK

(2009) Seung J. Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Signaling pathways involved in phase II gene induction by α, β-unsaturated aldehydes

(2009) Hongqiao Zhang et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Acrolein Induces Inflammatory Response Underlying Endothelial Dysfunction

(2008) Yong Seek Park et al.   Annals of the New York Academy of Sciences

The chemistry of cell signaling by reactive oxygen and nitrogen species and 4-hydroxynonenal

(2008) Henry Jay Forman et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Genome-Wide Transcriptional Responses to Acrolein

(2008) Colin A. Thompson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

4-Hydroxynonenal enhances MMP-2 production in vascular smooth muscle cells via mitochondrial ROS-mediated activation of the Akt/NF-κB signaling pathways

(2008) Seung J. Lee et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative stress in environmental-induced carcinogenesis

(2008) Salvador Mena et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Acrolein Induces Heme Oxygenase-1 through PKC-δ and PI3K in Human Bronchial Epithelial Cells

(2007) Hongqiao Zhang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Glutathione level regulates HNE-induced genotoxicity in human erythroleukemia cells

(2007) Umesh C.S. Yadav et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY