pH-Channeling in Cancer: How pH-Dependence of Cation Channels Shapes Cancer Pathophysiology
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Title
pH-Channeling in Cancer: How pH-Dependence of Cation Channels Shapes Cancer Pathophysiology
Authors
Keywords
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Journal
Cancers
Volume 12, Issue 9, Pages 2484
Publisher
MDPI AG
Online
2020-09-02
DOI
10.3390/cancers12092484
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- TRPV4 mediates tumor-derived endothelial cell migration via arachidonic acid-activated actin remodeling
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- Acidic Extracellular pH Promotes Activation of Integrin αvβ3
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- Role of Myeloid-Derived Suppressor Cells in Amelioration of Experimental Autoimmune Hepatitis Following Activation of TRPV1 Receptors by Cannabidiol
- (2011) Venkatesh L. Hegde et al. PLoS One
- CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans
- (2011) G. L. Beatty et al. SCIENCE
- The human P2X7 receptor and its role in innate immunity
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- Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers
- (2010) S. Pillozzi et al. BLOOD
- From the Background to the Spotlight: TASK Channels in Pathological Conditions
- (2010) Stefan Bittner et al. BRAIN PATHOLOGY
- Voltage-Gated Na+ Channel SCN5A Is a Key Regulator of a Gene Transcriptional Network That Controls Colon Cancer Invasion
- (2010) C. D. House et al. CANCER RESEARCH
- TRPM7 regulates the migration of human nasopharyngeal carcinoma cell by mediating Ca2+ influx
- (2010) Jian-Peng Chen et al. CELL CALCIUM
- Random mutagenesis screening indicates the absence of a separate H+-sensor in the pH-sensitive Kir channels
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- Dichloroacetate shifts the metabolism from glycolysis to glucose oxidation and exhibits synergistic growth inhibition with cisplatin in HeLa cells
- (2010) Fang INTERNATIONAL JOURNAL OF ONCOLOGY
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- (2010) Rajender K. Motiani et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The calcium-permeable non-selective cation channel TRPM2 is modulated by cellular acidification
- (2010) John G. Starkus et al. JOURNAL OF PHYSIOLOGY-LONDON
- Knockdown of Inwardly Rectifying Potassium Channel Kir2.2 Suppresses Tumorigenesis by Inducing Reactive Oxygen Species-Mediated Cellular Senescence
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- HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species
- (2010) Melania Capasso et al. NATURE IMMUNOLOGY
- Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
- (2010) Subhra K Biswas et al. NATURE IMMUNOLOGY
- Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
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- Ion channels and the hallmarks of cancer
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- Evidence that TRPM7 is required for breast cancer cell proliferation
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- Identification of the amino acid residues in the extracellular domain of rat P2X7receptor involved in functional inhibition by acidic pH
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- Orai1 and STIM1 Are Critical for Breast Tumor Cell Migration and Metastasis
- (2009) Shengyu Yang et al. CANCER CELL
- Receptor Channel TRPC6 Is a Key Mediator of Notch-Driven Glioblastoma Growth and Invasiveness
- (2009) S. Chigurupati et al. CANCER RESEARCH
- The functional network of ion channels in T lymphocytes
- (2009) Michael D. Cahalan et al. IMMUNOLOGICAL REVIEWS
- Voltage-gated Sodium Channel Activity Promotes Cysteine Cathepsin-dependent Invasiveness and Colony Growth of Human Cancer Cells
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- Modulation of TRPM2 by acidic pH and the underlying mechanisms for pH sensitivity
- (2009) Jianyang Du et al. JOURNAL OF GENERAL PHYSIOLOGY
- The glycocalyx maintains a cell surface pH nanoenvironment crucial for integrin-mediated migration of human melanoma cells
- (2009) Hermann Krähling et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Protons make tumor cells move like clockwork
- (2009) Christian Stock et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue
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- Novel role for the transient receptor potential channel TRPM2 in prostate cancer cell proliferation
- (2009) X Zeng et al. PROSTATE CANCER AND PROSTATIC DISEASES
- Dynamics of single potassium channel proteins in the plasma membrane of migrating cells
- (2008) Volodymyr Nechyporuk-Zloy et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Expression of Kir 4.1 in human astrocytic tumors: Correlation with pathologic grade
- (2008) Ge Tan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Effects of changes in extracellular pH and potassium concentration on Kv1.3 inactivation
- (2008) Sándor Somodi et al. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
- The intimate and mysterious relationship between proton channels and NADPH oxidase
- (2008) Boris Musset et al. FEBS LETTERS
- Capacitative calcium entry and transient receptor potential canonical 6 expression control human hepatoma cell proliferation
- (2008) Charbel El Boustany et al. HEPATOLOGY
- Talin at a glance
- (2008) D. R. Critchley et al. JOURNAL OF CELL SCIENCE
- Formation of Kv2.1-FAK complex as a mechanism of FAK activation, cell polarization and enhanced motility
- (2008) Jian-Feng Wei et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The two-pore domain potassium channel TASK3 functionally impacts glioma cell death
- (2008) Sven G. Meuth et al. JOURNAL OF NEURO-ONCOLOGY
- TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration
- (2008) Shinichiro Yamamoto et al. NATURE MEDICINE
- Englerin A, a Selective Inhibitor of Renal Cancer Cell Growth, fromPhyllanthus engleri
- (2008) Ranjala Ratnayake et al. ORGANIC LETTERS
- Structural model and functional significance of pH-dependent talin-actin binding for focal adhesion remodeling
- (2008) J. Srivastava et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The 9 1 integrin enhances cell migration by polyamine-mediated modulation of an inward-rectifier potassium channel
- (2008) G. W. deHart et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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