Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

Toward harmonized phenotyping of human myeloid-derived suppressor cells by flow cytometry: results from an interim study

(2016) Susanna Mandruzzato et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

(2016) Vinit Kumar et al.   TRENDS IN IMMUNOLOGY

GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells

(2015) B. H. Koehn et al.   BLOOD

RORC1 Regulates Tumor-Promoting “Emergency” Granulo-Monocytopoiesis

(2015) Laura Strauss et al.   CANCER CELL

Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected

(2015) Douglas Marvel et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor-induced myeloid deviation: when myeloid-derived suppressor cells meet tumor-associated macrophages

(2015) Stefano Ugel et al.   JOURNAL OF CLINICAL INVESTIGATION

Expression of Cationic Amino Acid Transporter 2 Is Required for Myeloid-Derived Suppressor Cell-Mediated Control of T Cell Immunity

(2015) C. Cimen Bozkus et al.   JOURNAL OF IMMUNOLOGY

Impaired gp100-Specific CD8 + T-Cell Responses in the Presence of Myeloid-Derived Suppressor Cells in a Spontaneous Mouse Melanoma Model

(2015) David G. Mairhofer et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The prognostic landscape of genes and infiltrating immune cells across human cancers

(2015) Andrew J Gentles et al.   NATURE MEDICINE

TNF Counterbalances the Emergence of M2 Tumor Macrophages

(2015) Franz Kratochvill et al.   Cell Reports

Requirement for Interactions of Natural Killer T Cells and Myeloid-Derived Suppressor Cells for Transplantation Tolerance

(2014) D. Hongo et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Myeloid-derived suppressor cell heterogeneity in human cancers

(2014) Samantha Solito et al.   Annals of the New York Academy of Sciences

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

Inhibition of Tumor-Derived Prostaglandin-E2 Blocks the Induction of Myeloid-Derived Suppressor Cells and Recovers Natural Killer Cell Activity

(2014) Y. Mao et al.   CLINICAL CANCER RESEARCH

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Myeloid-Derived Suppressor Activity Is Mediated by Monocytic Lineages Maintained by Continuous Inhibition of Extrinsic and Intrinsic Death Pathways

(2014) Jessica M. Haverkamp et al.   IMMUNITY

The Stress-Response Sensor Chop Regulates the Function and Accumulation of Myeloid-Derived Suppressor Cells in Tumors

(2014) Paul T. Thevenot et al.   IMMUNITY

Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer

(2014) Evgeniy B. Eruslanov et al.   JOURNAL OF CLINICAL INVESTIGATION

ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R–mediated apoptosis

(2014) Thomas Condamine et al.   JOURNAL OF CLINICAL INVESTIGATION

PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation

(2014) Muhammad Zaeem Noman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Proinflammatory S100 Proteins Regulate the Accumulation of Myeloid-Derived Suppressor Cells

(2014) P. Sinha et al.   JOURNAL OF IMMUNOLOGY

Subsets of Myeloid-Derived Suppressor Cells in Tumor-Bearing Mice

(2014) J.-I. Youn et al.   JOURNAL OF IMMUNOLOGY

Myeloid-Derived Suppressor Cells as a Potential Therapy for Experimental Autoimmune Myasthenia Gravis

(2014) Yan Li et al.   JOURNAL OF IMMUNOLOGY

Cross-talk among myeloid-derived suppressor cells, macrophages, and tumor cells impacts the inflammatory milieu of solid tumors

(2014) Daniel W. Beury et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

(2014) Andrea Viale et al.   NATURE

miR-142-3p Prevents Macrophage Differentiation during Cancer-Induced Myelopoiesis

(2013) Nada Sonda et al.   IMMUNITY

Subpopulations of myeloid-derived suppressor cells impair T cell responses through independent nitric oxide-related pathways

(2013) Patrick L. Raber et al.   INTERNATIONAL JOURNAL OF CANCER

Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis

(2013) Jeremy D. Waight et al.   JOURNAL OF CLINICAL INVESTIGATION

Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer

(2013) Je-In Youn et al.   NATURE IMMUNOLOGY

Up-Regulation of PD-L1, IDO, and Tregs in the Melanoma Tumor Microenvironment Is Driven by CD8+ T Cells

(2013) S. Spranger et al.   Science Translational Medicine

Myeloid-Derived Suppressor Cells in the Development of Lung Cancer

(2013) M. L. Ortiz et al.   Cancer Immunology Research

Neutrophils and granulocytic myeloid-derived suppressor cells: immunophenotyping, cell biology and clinical relevance in human oncology

(2012) Claudia A. Dumitru et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Aptamer-Mediated Blockade of IL4R  Triggers Apoptosis of MDSCs and Limits Tumor Progression

(2012) F. Roth et al.   CANCER RESEARCH

Anti-IL-6 receptor mAb eliminates myeloid-derived suppressor cells and inhibits tumor growth by enhancing T-cell responses

(2012) Kentaro Sumida et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Granulocytic myeloid-derived suppressor cells are cryosensitive and their frequency does not correlate with serum concentrations of colony-stimulating factors in head and neck cancer

(2012) Sokratis Trellakis et al.   Innate Immunity

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Comprehensive review on the HSC70 functions, interactions with related molecules and involvement in clinical diseases and therapeutic potential

(2012) Tuoen Liu et al.   PHARMACOLOGY & THERAPEUTICS

Transcriptomic Analysis Comparing Tumor-Associated Neutrophils with Granulocytic Myeloid-Derived Suppressor Cells and Normal Neutrophils

(2012) Zvi G. Fridlender et al.   PLoS One

Slow Disease Progression in a C57BL/6 Pten -Deficient Mouse Model of Prostate Cancer

(2011) Robert U. Svensson et al.   AMERICAN JOURNAL OF PATHOLOGY

Modulators of Arginine Metabolism Do Not Impact on Peripheral T-Cell Tolerance and Disease Progression in a Model of Spontaneous Prostate Cancer

(2011) N. Rigamonti et al.   CLINICAL CANCER RESEARCH

MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy

(2011) James Finke et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice

(2011) Tangying Lu et al.   JOURNAL OF CLINICAL INVESTIGATION

Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells

(2011) Barbara Molon et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing mice

(2011) Je-In Youn et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy

(2011) David G. DeNardo et al.   Cancer Discovery

Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13

(2010) S. L. Highfill et al.   BLOOD

Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes

(2010) K. Movahedi et al.   CANCER RESEARCH

Anti-inflammatory Triterpenoid Blocks Immune Suppressive Function of MDSCs and Improves Immune Response in Cancer

(2010) S. Nagaraj et al.   CLINICAL CANCER RESEARCH

Macrophages, innate immunity and cancer: balance, tolerance, and diversity

(2010) Alberto Mantovani et al.   CURRENT OPINION IN IMMUNOLOGY

Myeloid-derived suppressor cell heterogeneity and subset definition

(2010) Elisa Peranzoni et al.   CURRENT OPINION IN IMMUNOLOGY

IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function

(2010) Moshe Elkabets et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tumor-Induced Tolerance and Immune Suppression Depend on the C/EBPβ Transcription Factor

(2010) Ilaria Marigo et al.   IMMUNITY

Mechanism of T Cell Tolerance Induced by Myeloid-Derived Suppressor Cells

(2010) S. Nagaraj et al.   JOURNAL OF IMMUNOLOGY

Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

(2010) M. Kowanetz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN

(2009) Zvi G. Fridlender et al.   CANCER CELL

Myeloid-derived suppressor cells in mammary tumor progression in FVB Neu transgenic mice

(2009) Fuminori Abe et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Arginase I–Producing Myeloid-Derived Suppressor Cells in Renal Cell Carcinoma Are a Subpopulation of Activated Granulocytes

(2009) Paulo C. Rodriguez et al.   CANCER RESEARCH

Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF

(2009) Luigi Dolcetti et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mechanism Regulating Reactive Oxygen Species in Tumor-Induced Myeloid-Derived Suppressor Cells

(2009) C. A. Corzo et al.   JOURNAL OF IMMUNOLOGY

Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity

(2008) K. Movahedi et al.   BLOOD

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

(2008) Pingyan Cheng et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics

(2008) Naoki Umemura et al.   JOURNAL OF LEUKOCYTE BIOLOGY