KCa1.1 channels regulate β1-integrin function and cell adhesion in rheumatoid arthritis fibroblast-like synoviocytes

Functional KCa1.1 channels are crucial for regulating the proliferation, migration and differentiation of human primary skeletal myoblasts

(2016) Rajeev B Tajhya et al.   Cell Death & Disease

The cation channel Trpv2 is a new suppressor of arthritis severity, joint damage, and synovial fibroblast invasion

(2015) Teresina Laragione et al.   CLINICAL IMMUNOLOGY

Activation of Transient Receptor Potential Vanilloid 3 Channel Suppresses Adipogenesis

(2015) Sin Ying Cheung et al.   ENDOCRINOLOGY

Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance

(2015) Laetitia Seguin et al.   TRENDS IN CELL BIOLOGY

Toll-like receptor 2 (TLR2) induces migration and invasive mechanisms in rheumatoid arthritis

(2015) Trudy McGarry et al.   ARTHRITIS RESEARCH & THERAPY

KCNK10, a Tandem Pore Domain Potassium Channel, Is a Regulator of Mitotic Clonal Expansion during the Early Stage of Adipocyte Differentiation

(2014) Makoto Nishizuka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Paxilline inhibits BK channels by an almost exclusively closed-channel block mechanism

(2014) Yu Zhou et al.   JOURNAL OF GENERAL PHYSIOLOGY

Synoviocyte Stimulation by the LFA-1-Intercellular Adhesion Molecule-2-Ezrin-Akt Pathway in Rheumatoid Arthritis

(2014) K. Singh et al.   JOURNAL OF IMMUNOLOGY

KCa1.1 Inhibition Attenuates Fibroblast-like Synoviocyte Invasiveness and Ameliorates Disease in Rat Models of Rheumatoid Arthritis

(2014) Mark R. Tanner et al.   Arthritis & Rheumatology

IP-FCM platform detects the existence and regulator-caused dissociation of components in naturally assembled HSP90 complex

(2013) Fan-Fan Cao et al.   CYTOMETRY PART A

The POSH/JIP-1 scaffold network regulates TCR-mediated JNK1 signals and effector function in CD8+T cells

(2013) Cody A. Cunningham et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Bimodal voltage dependence of TRPA1: mutations of a key pore helix residue reveal strong intrinsic voltage-dependent inactivation

(2013) Xia Wan et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

TRPV1 Channels Are Functionally Coupled with BK(mSlo1) Channels in Rat Dorsal Root Ganglion (DRG) Neurons

(2013) Ying Wu et al.   PLoS One

PI3 Kinase δ Is a Key Regulator of Synoviocyte Function in Rheumatoid Arthritis

(2012) Beatrix Bartok et al.   AMERICAN JOURNAL OF PATHOLOGY

Trpc1 Ion Channel Modulates Phosphatidylinositol 3-Kinase/Akt Pathway during Myoblast Differentiation and Muscle Regeneration

(2012) Nadège Zanou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IGFBP5 induces cell adhesion, increases cell survival and inhibits cell migration in MCF-7 human breast cancer cells

(2012) A. Sureshbabu et al.   JOURNAL OF CELL SCIENCE

IP-FCM Measures Physiologic Protein-Protein Interactions Modulated by Signal Transduction and Small-Molecule Drug Inhibition

(2012) Stephen E. P. Smith et al.   PLoS One

NF-AT5 is a critical regulator of inflammatory arthritis

(2011) Hyung-Ju Yoon et al.   ARTHRITIS AND RHEUMATISM

Molecular mechanisms of activation of endothelial nitric oxide synthase mediated by transient receptor potential vanilloid type 1

(2011) L.-C. Ching et al.   CARDIOVASCULAR RESEARCH

KCa1.1 Potassium Channels Regulate Key Proinflammatory and Invasive Properties of Fibroblast-like Synoviocytes in Rheumatoid Arthritis

(2011) Xueyou Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Voltage- and temperature-dependent activation of TRPV3 channels is potentiated by receptor-mediated PI(4,5)P2hydrolysis

(2011) Julia F. Doerner et al.   JOURNAL OF GENERAL PHYSIOLOGY

Multiplex IP-FCM (immunoprecipitation-flow cytometry): Principles and guidelines for assessing physiologic protein–protein interactions in multiprotein complexes

(2011) Anya T. Bida et al.   METHODS

Quantitative Analysis of Protein Phosphorylations and Interactions by Multi-Colour IP-FCM as an Input for Kinetic Modelling of Signalling Networks

(2011) Sumit Deswal et al.   PLoS One

Integrins and their ligands in rheumatoid arthritis

(2011) Torsten Lowin et al.   ARTHRITIS RESEARCH & THERAPY

2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) D. Aletaha et al.   ANNALS OF THE RHEUMATIC DISEASES

TRPM3 channel stimulated by pregnenolone sulphate in synovial fibroblasts and negatively coupled to hyaluronan

(2010) Coziana Ciurtin et al.   BMC MUSCULOSKELETAL DISORDERS

Activation of Trpv4 Reduces the Hyperproliferative Phenotype of Cystic Cholangiocytes From an Animal Model of ARPKD

(2010) Sergio A. Gradilone et al.   GASTROENTEROLOGY

Adrenomedullin Inhibits IL-1β-Induced Rheumatoid Synovial Fibroblast Proliferation and MMPs, COX-2 and PGE2 Production

(2010) Eun-Gyeong Lee et al.   INFLAMMATION

Unknown

(2010) Teresina Laragione et al.   MOLECULAR MEDICINE

Adrenomedullin increases fibroblast-like synoviocyte adhesion to extracellular matrix proteins by upregulating integrin activation

(2010) Marie-Dominique Ah Kioon et al.   ARTHRITIS RESEARCH & THERAPY

Glucocorticoids increase α5 integrin expression and adhesion of synovial fibroblasts but inhibit ERK signaling, migration, and cartilage invasion

(2009) Torsten Lowin et al.   ARTHRITIS AND RHEUMATISM

TRPC1 Associates With BK Ca Channel to Form a Signal Complex in Vascular Smooth Muscle Cells

(2009) Hiu-Yee Kwan et al.   CIRCULATION RESEARCH

Development of a flow cytometric co-immunoprecipitation technique for the study of multiple protein-protein interactions and its application to T-cell receptor analysis

(2009) John S. Bridgeman et al.   CYTOMETRY PART A

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

(2009) Beatrix Bartok et al.   IMMUNOLOGICAL REVIEWS

α5β1 Integrin Engagement Increases Large Conductance, Ca2+-activated K+Channel Current and Ca2+Sensitivity through c-src-mediated Channel Phosphorylation

(2009) Yan Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor Necrosis Factor-Alpha (TNF-α) Enhances Functional Thermal and Chemical Responses of TRP Cation Channels in Human Synoviocytes

(2009) Mikhail Y Kochukov et al.   Molecular Pain

Calmodulin modulates Akt activity in human breast cancer cell lines

(2008) Christine M. Coticchia et al.   BREAST CANCER RESEARCH AND TREATMENT

Imaging of Effector Memory T Cells during a Delayed-Type Hypersensitivity Reaction and Suppression by Kv1.3 Channel Block

(2008) Melanie P. Matheu et al.   IMMUNITY

Potentiation of large conductance, Ca2+-activated K+(BK) channels by α5β1 integrin activation in arteriolar smooth muscle

(2008) Xin Wu et al.   JOURNAL OF PHYSIOLOGY-LONDON

TRPC channel activation by extracellular thioredoxin

(2008) Shang-Zhong Xu et al.   NATURE

The  9 1 integrin enhances cell migration by polyamine-mediated modulation of an inward-rectifier potassium channel

(2008) G. W. deHart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endocytic transport of integrins during cell migration and invasion

(2008) Patrick Caswell et al.   TRENDS IN CELL BIOLOGY