The human P2X7 receptor and its role in innate immunity

P2X7 Is a Scavenger Receptor for Apoptotic Cells in the Absence of Its Ligand, Extracellular ATP

(2011) B. J. Gu et al.   JOURNAL OF IMMUNOLOGY

Mutation of Putative N-Linked Glycosylation Sites on the Human Nucleotide Receptor P2X7Reveals a Key Residue Important for Receptor Function

(2010) Lisa Y. Lenertz et al.   BIOCHEMISTRY

NTPDase1 governs P2X7-dependent functions in murine macrophages

(2010) Sébastien A. Lévesque et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Trophic activity of a naturally occurring truncated isoform of the P2X7 receptor

(2010) Elena Adinolfi et al.   FASEB JOURNAL

Two haplotypes of the P2X7 receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1β secretion

(2010) Leanne Stokes et al.   FASEB JOURNAL

Metaanalysis of P2X7  gene polymorphisms and tuberculosis susceptibility

(2010) Jing Xiao et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Evidence for associations between the purinergic receptor P2X7 (P2RX7) and toxoplasmosis

(2010) S E Jamieson et al.   GENES AND IMMUNITY

The Hyposensitive N187D P2X7 Mutant Promotes Malignant Progression in Nude Mice

(2010) Jing-Hui Chong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Macrophages by P2X7-Induced Microvesicles from Myeloid Cells Is Mediated by Phospholipids and Is Partially Dependent on TLR4

(2010) L. M. Thomas et al.   JOURNAL OF IMMUNOLOGY

P2X7 Receptor-Mediated Killing of an Intracellular Parasite, Toxoplasma gondii, by Human and Murine Macrophages

(2010) M. P. Lees et al.   JOURNAL OF IMMUNOLOGY

A Screen for Endocytic Motifs

(2010) Patrycja Kozik et al.   TRAFFIC

Extracellular ATP dissociates nonmuscle myosin from P2X7 complex: this dissociation regulates P2X7 pore formation

(2009) Ben J. Gu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The P2X7-nonmuscle myosin membrane complex regulates phagocytosis of nonopsonized particles and bacteria by a pathway attenuated by extracellular ATP

(2009) B. J. Gu et al.   BLOOD

Activation of P2X7-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice

(2009) Wen Fu et al.   BMC CANCER

Autocrine regulation of T-cell activation by ATP release and P2X7 receptors

(2009) Linda Yip et al.   FASEB JOURNAL

Functional variants of the P2RX7 gene, aseptic osteolysis, and revision of the total hip arthroplasty: A preliminary study

(2009) F. Mrazek et al.   HUMAN IMMUNOLOGY

The P2X7 Receptor Drives Microglial Activation and Proliferation: A Trophic Role for P2X7R Pore

(2009) M. Monif et al.   JOURNAL OF NEUROSCIENCE

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

(2009) Toshimitsu Kawate et al.   NATURE

The P2X7 receptor mediates the uptake of organic cations in canine erythrocytes and mononuclear leukocytes: comparison to equivalent human cell types

(2009) Ryan O. Stevenson et al.   Purinergic Signalling

Regulation of P2X7 gene transcription

(2009) Lingyin Zhou et al.   Purinergic Signalling

Genetics of the P2X7 receptor and human disease

(2009) Stephen J. Fuller et al.   Purinergic Signalling

Physiological and pathological functions of P2X7 receptor in the spinal cord

(2009) Maria Luisa Cotrina et al.   Purinergic Signalling

P2X7 receptors regulate multiple types of membrane trafficking responses and non-classical secretion pathways

(2009) Yan Qu et al.   Purinergic Signalling

Inhibition of P2X7 receptors by divalent cations: old action and new insight

(2008) Lin-Hua Jiang   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Palmitoylation of the P2X7 receptor, an ATP-gated channel, controls its expression and association with lipid rafts

(2008) P. Gonnord et al.   FASEB JOURNAL

ATP-induced P2X7-associated uptake of large molecules involves distinct mechanisms for cations and anions in macrophages

(2008) J. Schachter et al.   JOURNAL OF CELL SCIENCE

ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1  and IL-18 secretion in an autocrine way

(2008) A. Piccini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA