Metabolic Plasticity of Melanoma Cells and Their Crosstalk With Tumor Microenvironment
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Metabolic Plasticity of Melanoma Cells and Their Crosstalk With Tumor Microenvironment
Authors
Keywords
-
Journal
Frontiers in Oncology
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-05-22
DOI
10.3389/fonc.2020.00722
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- EGFR/uPAR interaction as druggable target to overcome vemurafenib acquired resistance in melanoma cells
- (2019) Anna Laurenzana et al. EBioMedicine
- Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance
- (2019) Jonathan K. M. Lim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting metabolic reprogramming in metastatic melanoma: The key role of nicotinamide phosphoribosyltransferase (NAMPT)
- (2019) Valentina Audrito et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Targeting hypoxia-induced carbonic anhydrase IX enhances immune checkpoint blockade locally and systemically
- (2019) Shawn C Chafe et al. Cancer Immunology Research
- Role of Mitochondria in the Mechanism(s) of Action of Metformin
- (2019) Guillaume Vial et al. Frontiers in Endocrinology
- Mitochondrial complex I inhibitor deguelin induces metabolic reprogramming and sensitizes vemurafenib-resistant BRAF V600E mutation bearing metastatic melanoma cells
- (2019) Evan L. Carpenter et al. MOLECULAR CARCINOGENESIS
- MITF controls the TCA cycle to modulate the melanoma hypoxia response
- (2019) Pakavarin Louphrasitthiphol et al. Pigment Cell & Melanoma Research
- Extracellular acidosis triggers a senescence‐like phenotype in human melanoma cells
- (2019) Ines Böhme et al. Pigment Cell & Melanoma Research
- Metabolic flexibility in melanoma: A potential therapeutic target
- (2019) Maria Rosaria Ruocco et al. SEMINARS IN CANCER BIOLOGY
- Cellular and molecular biology of cancer stem cells in melanoma: Possible therapeutic implications
- (2019) Monica Marzagalli et al. SEMINARS IN CANCER BIOLOGY
- Nodal Facilitates Differentiation of Fibroblasts to Cancer-Associated Fibroblasts that Support Tumor Growth in Melanoma and Colorectal Cancer
- (2019) Ziqian Li et al. Cells
- Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence
- (2019) Michal Harel et al. CELL
- A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of BRAF-mutated Melanoma to MAPK Inhibitors
- (2019) Andrea Aloia et al. CLINICAL CANCER RESEARCH
- Unraveling the crosstalk between melanoma and immune cells in the tumor microenvironment
- (2019) Monica Marzagalli et al. SEMINARS IN CANCER BIOLOGY
- Insights into Thymus Development and Viral Thymic Infections
- (2019) Francesco Albano et al. Viruses-Basel
- Development of a Stromal Microenvironment Experimental Model Containing Proto-Myofibroblast Like Cells and Analysis of Its Crosstalk with Melanoma Cells: A New Tool to Potentiate and Stabilize Tumor Suppressor Phenotype of Dermal Myofibroblasts
- (2019) Angelica Avagliano et al. Cells
- Targeting L-Lactate Metabolism to Overcome Resistance to Immune Therapy of Melanoma and Other Tumor Entities
- (2019) René G. Feichtinger et al. Journal of Oncology
- Metabolic heterogeneity confers differences in melanoma metastatic potential
- (2019) Alpaslan Tasdogan et al. NATURE
- Targeting Glutamine Metabolism for Cancer Treatment
- (2018) Yeon-Kyung Choi et al. Biomolecules & Therapeutics
- Melanoma: What do all the mutations mean?
- (2018) Elizabeth J. Davis et al. CANCER
- Targeting tumor-associated acidity in cancer immunotherapy
- (2018) Ruben Lacroix et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential
- (2018) Liqin Wang et al. CELL
- Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy
- (2018) Tina Cascone et al. Cell Metabolism
- Oxidative Phosphorylation as an Emerging Target in Cancer Therapy
- (2018) Thomas M. Ashton et al. CLINICAL CANCER RESEARCH
- Fibroblasts in the Tumor Microenvironment: Shield or Spear?
- (2018) Twana Alkasalias et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Glucose metabolism and NRF2 coordinate the antioxidant response in melanoma resistant to MAPK inhibitors
- (2018) Raeeka Khamari et al. Cell Death & Disease
- Dual suppression of inner and outer mitochondrial membrane functions augments apoptotic responses to oncogenic MAPK inhibition
- (2018) Madhavika N. Serasinghe et al. Cell Death & Disease
- Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins
- (2018) Maomao Zhang et al. Cancer Discovery
- Metabolic Reprogramming of Cancer Associated Fibroblasts: The Slavery of Stromal Fibroblasts
- (2018) Angelica Avagliano et al. Biomed Research International
- Multifaceted Role of the Urokinase-Type Plasminogen Activator (uPA) and Its Receptor (uPAR): Diagnostic, Prognostic, and Therapeutic Applications
- (2018) Niaz Mahmood et al. Frontiers in Oncology
- Impact of l-Arginine Metabolism on Immune Response and Anticancer Immunotherapy
- (2018) Sun-Hee Kim et al. Frontiers in Oncology
- Metabolic reprogramming of stromal fibroblasts by melanoma exosome microRNA favours a pre-metastatic microenvironment
- (2018) Shin La Shu et al. Scientific Reports
- Metformin: Focus on Melanoma
- (2018) Emilie Jaune et al. Frontiers in Endocrinology
- Myrtenal-induced V-ATPase inhibition - A toxicity mechanism behind tumor cell death and suppressed migration and invasion in melanoma
- (2018) Brunna Xavier Martins et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Oxidative Stress and Antioxidants in the Pathophysiology of Malignant Melanoma
- (2018) Elena Obrador et al. BIOLOGICAL CHEMISTRY
- SOX2 as a novel contributor of oxidative metabolism in melanoma cells
- (2018) Elena Andreucci et al. Cell Communication and Signaling
- Acidic microenvironment plays a key role in human melanoma progression through a sustained exosome mediated transfer of clinically relevant metastatic molecules
- (2018) Zaira Boussadia et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Bioenergetic modulation with the mitochondria uncouplers SR4 and niclosamide prevents proliferation and growth of treatment-naïve and vemurafenib-resistant melanomas
- (2018) James L. Figarola et al. Oncotarget
- Connexin 43 (Cx43) in cancer: Implications for therapeutic approaches via gap junctions
- (2018) Emily E. Bonacquisti et al. CANCER LETTERS
- Metabolic targeting synergizes with MAPK inhibition and delays drug resistance in melanoma
- (2018) Christina Brummer et al. CANCER LETTERS
- Targeting invasive properties of melanoma cells
- (2017) Imanol Arozarena et al. FEBS Journal
- uPA/uPAR system activation drives a glycolytic phenotype in melanoma cells
- (2017) Anna Laurenzana et al. INTERNATIONAL JOURNAL OF CANCER
- Carbonic anhydrase IX inhibition affects viability of cancer cells adapted to extracellular acidosis
- (2017) Elena Andreucci et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Nicotinamide Phosphoribosyltransferase (NAMPT) as a Therapeutic Target in BRAF-Mutated Metastatic Melanoma
- (2017) Valentina Audrito et al. JNCI-Journal of the National Cancer Institute
- ERRα Maintains Mitochondrial Oxidative Metabolism and Constitutes an Actionable Target in PGC1α-Elevated Melanomas
- (2017) Chi Luo et al. MOLECULAR CANCER RESEARCH
- Disrupting G6PD-mediated Redox homeostasis enhances chemosensitivity in colorectal cancer
- (2017) H-Q Ju et al. ONCOGENE
- Expression of Glut-1 in Malignant Melanoma and Melanocytic Nevi: an Immunohistochemical Study of 400 Cases
- (2017) Miroslav Důra et al. PATHOLOGY & ONCOLOGY RESEARCH
- Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications
- (2017) Grant M. Fischer et al. Pigment Cell & Melanoma Research
- Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
- (2017) Kenji Chamoto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glucose-6-phosphate dehydrogenase and transketolase modulate breast cancer cell metabolic reprogramming and correlate with poor patient outcome
- (2017) Adrián Benito et al. Oncotarget
- Biglycan expression in the melanoma microenvironment promotes invasiveness via increased tissue stiffness inducing integrin-β1 expression
- (2017) Hana Andrlová et al. Oncotarget
- Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells
- (2017) Lan-Feng Dong et al. eLife
- Nicotinamide Phosphoribosyltransferase (NAMPT) as a Therapeutic Target in BRAF-Mutated Metastatic Melanoma
- (2017) Valentina Audrito et al. JNCI-Journal of the National Cancer Institute
- Why target the tumor stroma in melanoma?
- (2017) James Hutchenreuther et al. Journal of Cell Communication and Signaling
- 18F-FDG PET/CT Imaging in Oncology
- (2017) Ahmad Almuhaideb et al. ANNALS OF SAUDI MEDICINE
- AMPK activation by GSK621 inhibits human melanoma cells in vitro and in vivo
- (2016) Lezi Chen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Acidosis Acts through HSP90 in a PHD/VHL-Independent Manner to Promote HIF Function and Stem Cell Maintenance in Glioma
- (2016) Alina Filatova et al. CANCER RESEARCH
- Adipocyte Exosomes Promote Melanoma Aggressiveness through Fatty Acid Oxidation: A Novel Mechanism Linking Obesity and Cancer
- (2016) Ikrame Lazar et al. CANCER RESEARCH
- Metformin is also effective on lactic acidosis-exposed melanoma cells switched to oxidative phosphorylation
- (2016) Silvia Peppicelli et al. CELL CYCLE
- The metabolic microenvironment of melanomas: Prognostic value of MCT1 and MCT4
- (2016) Céline Pinheiro et al. CELL CYCLE
- LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells
- (2016) Almut Brand et al. Cell Metabolism
- Expression of Glut-1 in Normal Endometrium and Endometrial Lesions: Analysis of 336 Cases
- (2016) Kristýna Němejcová et al. INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY
- Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors
- (2016) Gao Zhang et al. JOURNAL OF CLINICAL INVESTIGATION
- Angiogenesis in melanoma: an update with a focus on current targeted therapies
- (2016) George Jour et al. JOURNAL OF CLINICAL PATHOLOGY
- Mechanisms of Melanoma Promotion by Ultraviolet Radiation
- (2016) Thomas M. Rünger JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Stromal Senescence By Prolonged CDK4/6 Inhibition Potentiates Tumor Growth
- (2016) Xiangnan Guan et al. MOLECULAR CANCER RESEARCH
- Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis
- (2016) Xinjian Li et al. MOLECULAR CELL
- A PGC1α-mediated transcriptional axis suppresses melanoma metastasis
- (2016) Chi Luo et al. NATURE
- Melanoma miRNA trafficking controls tumour primary niche formation
- (2016) Shani Dror et al. NATURE CELL BIOLOGY
- Cancer metabolism: a therapeutic perspective
- (2016) Ubaldo E. Martinez-Outschoorn et al. Nature Reviews Clinical Oncology
- Glycolysis and the pentose phosphate pathway are differentially associated with the dichotomous regulation of glioblastoma cell migration versus proliferation
- (2016) Annegret Kathagen-Buhmann et al. NEURO-ONCOLOGY
- Metabolic rewiring in melanoma
- (2016) B I Ratnikov et al. ONCOGENE
- Targeting metabolic reprogramming as a potential therapeutic strategy in melanoma
- (2016) Lorey K. Smith et al. PHARMACOLOGICAL RESEARCH
- Acidic tumor microenvironment in human melanoma
- (2016) Ines Böhme et al. Pigment Cell & Melanoma Research
- Mitochondrial oxidative phosphorylation controls cancer cell’s life and death decisions upon exposure to MAPK inhibitors
- (2016) Paola Corazao-Rozas et al. Oncotarget
- MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4
- (2016) Candice Sun Hong et al. Cell Reports
- Cancer: An Oxidative Crosstalk between Solid Tumor Cells and Cancer Associated Fibroblasts
- (2016) Alessandro Arcucci et al. Biomed Research International
- Dermal fibroblasts induce cell cycle arrest and block epithelial-mesenchymal transition to inhibit the early stage melanoma development
- (2016) Linli Zhou et al. Cancer Medicine
- Irreversible Inhibition of Glutathione S-Transferase by Phenethyl Isothiocyanate (PEITC), a Dietary Cancer Chemopreventive Phytochemical
- (2016) Vandana Kumari et al. PLoS One
- Proton channels and exchangers in cancer
- (2015) Enrico Pierluigi Spugnini et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Overexpression of connexin 43 reduces melanoma proliferative and metastatic capacity
- (2015) A Tittarelli et al. BRITISH JOURNAL OF CANCER
- Cancer statistics, 2015
- (2015) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Neutralization of Tumor Acidity Improves Antitumor Responses to Immunotherapy
- (2015) Shari Pilon-Thomas et al. CANCER RESEARCH
- Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
- (2015) Ping-Chih Ho et al. CELL
- Mitochondrial Genome Acquisition Restores Respiratory Function and Tumorigenic Potential of Cancer Cells without Mitochondrial DNA
- (2015) An S. Tan et al. Cell Metabolism
- Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway
- (2015) Valéry L. Payen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Effects of extracellular pH and hypoxia on the function and development of antigen-specific cytotoxic T lymphocytes
- (2015) Yohko Nakagawa et al. IMMUNOLOGY LETTERS
- Pyruvate carboxylase is critical for non–small-cell lung cancer proliferation
- (2015) Katherine Sellers et al. JOURNAL OF CLINICAL INVESTIGATION
- Skin Cancer Epidemiology, Detection, and Management
- (2015) Sumul Ashok Gandhi et al. MEDICAL CLINICS OF NORTH AMERICA
- Mitochondrial Division Is Requisite to RAS-Induced Transformation and Targeted by Oncogenic MAPK Pathway Inhibitors
- (2015) Madhavika N. Serasinghe et al. MOLECULAR CELL
- Resistance to BRAF inhibitors induces glutamine dependency in melanoma cells
- (2015) Franziska Baenke et al. Molecular Oncology
- Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis
- (2015) Shiran Rabinovich et al. NATURE
- Pyruvate kinase: Function, regulation and role in cancer
- (2015) William J. Israelsen et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Molecular drivers of cellular metabolic reprogramming in melanoma
- (2015) Cecilie Abildgaard et al. TRENDS IN MOLECULAR MEDICINE
- Role of hypoxia-inducible factor-1α, carbonic anhydrase-IX, glucose transporter-1 and vascular endothelial growth factor associated with lymph node metastasis and recurrence in patients with locally advanced cervical cancer
- (2015) KEITA IWASAKI et al. Oncology Letters
- MYC, Metabolism, and Cancer
- (2015) Z. E. Stine et al. Cancer Discovery
- Glucose transporter isoform 1 expression enhances metastasis of malignant melanoma cells
- (2015) Andreas Koch et al. Oncotarget
- Metabolic Reprogramming of Cancer-Associated Fibroblasts by IDH3α Downregulation
- (2015) Daoxiang Zhang et al. Cell Reports
- Perspective of Targeting Cancer-Associated Fibroblasts in Melanoma
- (2015) Linli Zhou et al. Journal of Cancer
- Emerging Roles of Exosomes in Normal and Pathological Conditions: New Insights for Diagnosis and Therapeutic Applications
- (2015) Julieta De Toro et al. Frontiers in Immunology
- Cancer-Associated Fibroblasts: Their Characteristics and Their Roles in Tumor Growth
- (2015) Kazuyoshi Shiga et al. Cancers
- The Tumor Cytosol miRNAs, Fluid miRNAs, and Exosome miRNAs in Lung Cancer
- (2015) Xin Qin et al. Frontiers in Oncology
- Pyruvate Carboxylase Is Up-Regulated in Breast Cancer and Essential to Support Growth and Invasion of MDA-MB-231 Cells
- (2015) Phatchariya Phannasil et al. PLoS One
- The role of melanogenesis in regulation of melanoma behavior: Melanogenesis leads to stimulation of HIF-1α expression and HIF-dependent attendant pathways
- (2014) A. Slominski et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1 and Oxidative Phosphorylation in Melanoma
- (2014) Y. N. V. Gopal et al. CANCER RESEARCH
- Targeting Mitochondrial Oxidative Metabolism in Melanoma Causes Metabolic Compensation through Glucose and Glutamine Utilization
- (2014) J.-H. Lim et al. CANCER RESEARCH
- Analysis of extracellular superoxide dismutase and Akt in ascending aortic aneurysm with tricuspid or bicuspid aortic valve
- (2014) A. Arcucci et al. EUROPEAN JOURNAL OF HISTOCHEMISTRY
- Targeting glutamine transport to suppress melanoma cell growth
- (2014) Qian Wang et al. INTERNATIONAL JOURNAL OF CANCER
- Melanocytes as Instigators and Victims of Oxidative Stress
- (2014) Laurence Denat et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
- (2014) Oscar R. Colegio et al. NATURE
- PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis
- (2014) Valerie S. LeBleu et al. NATURE CELL BIOLOGY
- Redox Modulation of FAK Controls Melanoma Survival - Role of NOX4
- (2014) Cristiane Ribeiro-Pereira et al. PLoS One
- The pentose phosphate pathway and cancer
- (2014) Krushna C. Patra et al. TRENDS IN BIOCHEMICAL SCIENCES
- PGC1α Expression Defines a Subset of Human Melanoma Tumors with Increased Mitochondrial Capacity and Resistance to Oxidative Stress
- (2013) Francisca Vazquez et al. CANCER CELL
- Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF
- (2013) Rizwan Haq et al. CANCER CELL
- Regulation of pyruvate metabolism and human disease
- (2013) Lawrence R. Gray et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Acidic pH via NF-κB favours VEGF-C expression in human melanoma cells
- (2013) Silvia Peppicelli et al. CLINICAL & EXPERIMENTAL METASTASIS
- Navigating the Therapeutic Complexity of PI3K Pathway Inhibition in Melanoma
- (2013) L. N. Kwong et al. CLINICAL CANCER RESEARCH
- Vacuolar H+ ATPase expression and activity is required for Rab27B-dependent invasive growth and metastasis of breast cancer
- (2013) An Hendrix et al. INTERNATIONAL JOURNAL OF CANCER
- Targeting lactate metabolism for cancer therapeutics
- (2013) Joanne R. Doherty et al. JOURNAL OF CLINICAL INVESTIGATION
- Exosomes in tumor microenvironment influence cancer progression and metastasis
- (2013) Christoph Kahlert et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways
- (2013) Jeongsoon Park et al. MOLECULAR CELL
- Melanoma’s connections to the tumour microenvironment
- (2013) Johanna M. Brandner et al. PATHOLOGY
- New Aspects of an Old Drug – Diclofenac Targets MYC and Glucose Metabolism in Tumor Cells
- (2013) Eva Gottfried et al. PLoS One
- Phenformin enhances the therapeutic benefit of BRAFV600E inhibition in melanoma
- (2013) P. Yuan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of Melanin in Melanocyte Dysregulation of Reactive Oxygen Species
- (2013) Noah C. Jenkins et al. Biomed Research International
- Upcoming strategies for the treatment of metastatic melanoma
- (2012) Francesco Spagnolo et al. ARCHIVES OF DERMATOLOGICAL RESEARCH
- Markers of mitochondrial dysfunction during the diclofenac-induced apoptosis in melanoma cell lines
- (2012) Francesco Albano et al. BIOCHIMIE
- The Role of the PI3K-AKT Pathway in Melanoma
- (2012) Michael A. Davies CANCER JOURNAL
- Chronic Autophagy Is a Cellular Adaptation to Tumor Acidic pH Microenvironments
- (2012) Jonathan W. Wojtkowiak et al. CANCER RESEARCH
- Loss of stromal caveolin-1 expression in malignant melanoma metastases predicts poor survival
- (2012) Karen N. Wu et al. CELL CYCLE
- Two-compartment tumor metabolism: Autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cells
- (2012) Ahmed F. Salem et al. CELL CYCLE
- Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis, via glycolysis and ketone production
- (2012) Claudia Capparelli et al. CELL CYCLE
- Autophagy Is a Protective Mechanism for Human Melanoma Cells under Acidic Stress
- (2012) Maria Lucia Marino et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NADPH Oxidase 1 Overexpression Enhances Invasion via Matrix Metalloproteinase-2 and Epithelial–Mesenchymal Transition in Melanoma Cells
- (2012) Feng Liu et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- AMPK activators inhibit the proliferation of human melanomas bearing the activated MAPK pathway
- (2012) Carlotta Petti et al. MELANOMA RESEARCH
- Pyruvate Kinase M2 Regulates Gene Transcription by Acting as a Protein Kinase
- (2012) Xueliang Gao et al. MOLECULAR CELL
- ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect
- (2012) Weiwei Yang et al. NATURE CELL BIOLOGY
- Tumor Cell Plasticity and Angiogenesis in Human Melanomas
- (2012) Daniela Mihic-Probst et al. PLoS One
- Inhibition of Mitochondrial Respiration and Rapid Depletion of Mitochondrial Glutathione by β-Phenethyl Isothiocyanate: Mechanisms for Anti-Leukemia Activity
- (2011) Gang Chen et al. ANTIOXIDANTS & REDOX SIGNALING
- NRAS mutation status is an independent prognostic factor in metastatic melanoma
- (2011) John A. Jakob et al. CANCER
- Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion
- (2011) B. Dirat et al. CANCER RESEARCH
- Tumor lactic acidosis suppresses CTL function by inhibition of p38 and JNK/c-Jun activation
- (2011) Anna N. Mendler et al. INTERNATIONAL JOURNAL OF CANCER
- Comparative Metabolic Flux Profiling of Melanoma Cell Lines
- (2011) David A. Scott et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma
- (2011) Corine Bertolotto et al. NATURE
- Interfering with pH regulation in tumours as a therapeutic strategy
- (2011) Dario Neri et al. NATURE REVIEWS DRUG DISCOVERY
- Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF
- (2011) E. Feige et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Connexin 43 hemichannel regulates H9c2 cell proliferation by modulating intracellular ATP and [Ca2+]
- (2010) D. Song et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- AMP-activated kinase (AMPK)-generated signals in malignant melanoma cell growth and survival
- (2010) Jennifer Woodard et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Constitutive HIF-1 activity in malignant melanoma
- (2010) Silke Kuphal et al. EUROPEAN JOURNAL OF CANCER
- Hypoxia-induced metabolic shifts in cancer cells: Moving beyond the Warburg effect
- (2010) Aalim M. Weljie et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Arginine deprivation and argininosuccinate synthetase expression in the treatment of cancer
- (2010) Barbara Delage et al. INTERNATIONAL JOURNAL OF CANCER
- Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer
- (2010) Johanna Chiche et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Melanoma Antigen-11 Inhibits the Hypoxia-Inducible Factor Prolyl Hydroxylase 2 and Activates Hypoxic Response
- (2009) O. Aprelikova et al. CANCER RESEARCH
- NADPH Oxidase 4 Contributes to Transformation Phenotype of Melanoma Cells by Regulating G2-M Cell Cycle Progression
- (2009) M. Yamaura et al. CANCER RESEARCH
- Metabolic Approaches to Treatment of Melanoma
- (2009) P. Hersey et al. CLINICAL CANCER RESEARCH
- Lactate dehydrogenase 5 expression in melanoma increases with disease progression and is associated with expression of Bcl-XL and Mcl-1, but not Bcl-2 proteins
- (2009) Liqing Zhuang et al. MODERN PATHOLOGY
- Expression and function of hypoxia inducible factor-1 alpha in human melanoma under non-hypoxic conditions
- (2009) Caroline N Mills et al. Molecular Cancer
- Oncogenic B-RAF Negatively Regulates the Tumor Suppressor LKB1 to Promote Melanoma Cell Proliferation
- (2009) Bin Zheng et al. MOLECULAR CELL
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
- (2009) Carles Cantó et al. NATURE
- Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer
- (2009) R J DeBerardinis et al. ONCOGENE
- Frequent mutations in the MITF pathway in melanoma
- (2009) Julia C. Cronin et al. Pigment Cell & Melanoma Research
- A novel AKT3 mutation in melanoma tumours and cell lines
- (2008) M A Davies et al. BRITISH JOURNAL OF CANCER
- Hypoxia-inducible factor (HIF)-1 directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF)
- (2008) Z.-B. Han et al. CARCINOGENESIS
- Pyruvate kinase M2 is a phosphotyrosine-binding protein
- (2008) Heather R. Christofk et al. NATURE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now