TRPM2 ion channels regulate macrophage polarization and gastric inflammation during Helicobacter pylori infection

Ion Channels in Innate and Adaptive Immunity

(2015) Stefan Feske et al.   Annual Review of Immunology

Transient Receptor Potential Melastatin 2 Protects Mice against Polymicrobial Sepsis by Enhancing Bacterial Clearance

(2014) XiaoWei Qian et al.   ANESTHESIOLOGY

Mg2+- and ATP-dependent inhibition of transient receptor potential melastatin 7 by oxidative stress

(2014) Hana Inoue et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive Oxygen Species Prevent Imiquimod-Induced Psoriatic Dermatitis through Enhancing Regulatory T Cell Function

(2014) Hyung-Ran Kim et al.   PLoS One

Purinergic and Calcium Signaling in Macrophage Function and Plasticity

(2014) Bimal N. Desai et al.   Frontiers in Immunology

Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

(2013) F. O. Martinez et al.   BLOOD

TRPM2 channels are not required for acute airway inflammation in OVA-induced severe allergic asthma in mice

(2013) Adriana Sumoza-Toledo et al.   Journal of Inflammation-London

Kv3 channel assembly, trafficking and activity are regulated by zinc through different binding sites

(2013) Yuanzheng Gu et al.   JOURNAL OF PHYSIOLOGY-LONDON

A key role for Mg2+in TRPM7's control of ROS levels during cell stress

(2012) Hsiang-Chin Chen et al.   BIOCHEMICAL JOURNAL

TRPM2 Contributes to Inflammatory and Neuropathic Pain through the Aggravation of Pronociceptive Inflammatory Responses in Mice

(2012) K. Haraguchi et al.   JOURNAL OF NEUROSCIENCE

Redox signal-mediated sensitization of transient receptor potential melastatin 2 (TRPM2) to temperature affects macrophage functions

(2012) M. Kashio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased Expression of the Transient Receptor Potential Melastatin 7 Channel Is Critically Involved in Lipopolysaccharide-Induced Reactive Oxygen Species-Mediated Neuronal Death

(2011) Felipe Nuñez-Villena et al.   ANTIOXIDANTS & REDOX SIGNALING

Dendritic cell maturation and chemotaxis is regulated by TRPM2-mediated lysosomal Ca2+ release

(2011) Adriana Sumoza-Toledo et al.   FASEB JOURNAL

Mitochondrial reactive oxygen species drive proinflammatory cytokine production: Figure 1.

(2011) Edwina Naik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

(2011) Ariel C. Bulua et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation

(2011) Anke Di et al.   NATURE IMMUNOLOGY

Ncf1 (p47phox) Is Essential for Direct Regulatory T Cell Mediated Suppression of CD4+ Effector T Cells

(2011) Olga Efimova et al.   PLoS One

Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes

(2011) H. Knowles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redox biology and gastric carcinogenesis: the role ofHelicobacter pylori

(2011) Osamu Handa et al.   REDOX REPORT

Transient Receptor Potential Melastatin 2 Is Required for Lipopolysaccharide-Induced Cytokine Production in Human Monocytes

(2010) Janine Wehrhahn et al.   JOURNAL OF IMMUNOLOGY

TRPM7 Activates m-Calpain by Stress-Dependent Stimulation of p38 MAPK and c-Jun N-Terminal Kinase

(2010) Li-Ting Su et al.   JOURNAL OF MOLECULAR BIOLOGY

Regulation of superoxide production in neutrophils: role of calcium influx

(2008) Sabrina Bréchard et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The calcium-activated nonselective cation channel TRPM4 is essential for the migration but not the maturation of dendritic cells

(2008) Gaëtan Barbet et al.   NATURE IMMUNOLOGY

TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration

(2008) Shinichiro Yamamoto et al.   NATURE MEDICINE