Voltage and pH sensing by the voltage-gated proton channel, H V 1

Properties of the Voltage-Gated Proton Channel Gating Currents

(2018) Emerson M. Carmona et al.   BIOPHYSICAL JOURNAL

Gating Currents in Hv1 Proton Channels

(2018) Victor De La Rosa et al.   BIOPHYSICAL JOURNAL

Post-translational cleavage of Hv1 in human sperm tunes pH- and voltage-dependent gating

(2017) Thomas K. Berger et al.   JOURNAL OF PHYSIOLOGY-LONDON

RNA SEQ Analysis Indicates that the AE3 Cl−/HCO3 − Exchanger Contributes to Active Transport-Mediated CO2 Disposal in Heart

(2017) Kanimozhi Vairamani et al.   Scientific Reports

H+ channels in embryonic Biomphalaria glabrata cell membranes: Putative roles in snail host-schistosome interactions

(2017) Brandon J. Wright et al.   PLoS Neglected Tropical Diseases

Identification of a vacuolar proton channel that triggers the bioluminescent flash in dinoflagellates

(2017) Juan D. Rodriguez et al.   PLoS One

Comparison between mouse and sea urchin orthologs of voltage-gated proton channel suggests role of S3 segment in activation gating

(2016) Souhei Sakata et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Identification of an HV 1 voltage-gated proton channel in insects

(2016) Gustavo Chaves et al.   FEBS Journal

Insights into the structure and function of HV1 from a meta-analysis of mutation studies

(2016) Thomas E. DeCoursey et al.   JOURNAL OF GENERAL PHYSIOLOGY

Does Proton Conduction in the Voltage-Gated H+ Channel hHv1 Involve Grotthuss-Like Hopping via Acidic Residues?

(2016) Siri C. van Keulen et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Effects of unsaturated fatty acids on the kinetics of voltage-gated proton channels heterologously expressed in cultured cells

(2016) Akira Kawanabe et al.   JOURNAL OF PHYSIOLOGY-LONDON

On the role of water density fluctuations in the inhibition of a proton channel

(2016) Eleonora Gianti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acid activation mechanism of the influenza A M2 proton channel

(2016) Ruibin Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pado, a fluorescent protein with proton channel activity can optically monitor membrane potential, intracellular pH, and map gap junctions

(2016) Bok Eum Kang et al.   Scientific Reports

Proton currents constrain structural models of voltage sensor activation

(2016) Aaron L Randolph et al.   eLife

The isolated voltage sensing domain of the Shaker potassium channel forms a voltage-gated cation channel

(2016) Juan Zhao et al.   eLife

Gating Mechanisms of Voltage-Gated Proton Channels

(2015) Yasushi Okamura et al.   Annual Review of Biochemistry

The Voltage-Gated Proton Channel: A Riddle, Wrapped in a Mystery, inside an Enigma

(2015) Thomas E. DeCoursey   BIOCHEMISTRY

Tryptophan 207 is crucial to the unique properties of the human voltage-gated proton channel, hHV1

(2015) Vladimir V. Cherny et al.   JOURNAL OF GENERAL PHYSIOLOGY

Mapping the Gating and Permeation Pathways in the Voltage-Gated Proton Channel Hv1

(2015) Adam Chamberlin et al.   JOURNAL OF MOLECULAR BIOLOGY

The Influenza M2 Cytoplasmic Tail Changes the Proton-Exchange Equilibria and the Backbone Conformation of the Transmembrane Histidine Residue to Facilitate Proton Conduction

(2015) Shu Y. Liao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A specialized molecular motion opens the Hv1 voltage-gated proton channel

(2015) Laetitia Mony et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural revelations of the human proton channel

(2015) Thomas E. DeCoursey   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resting state of the human proton channel dimer in a lipid bilayer

(2015) Qufei Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic Short Hydrogen Bonds in Histidine Tetrad of Full-Length M2 Proton Channel Reveal Tetrameric Structural Heterogeneity and Functional Mechanism

(2015) Yimin Miao et al.   STRUCTURE

A specialized molecular motion opens the Hv1 voltage-gated proton channel

(2015) Laetitia Mony et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Selectivity Mechanism of the Voltage-gated Proton Channel, HV1

(2015) Todor Dudev et al.   Scientific Reports

Hv1 Proton Channel Opening Is Preceded by a Voltage-independent Transition

(2014) Carlos A. Villalba-Galea   BIOPHYSICAL JOURNAL

Proton channel models

(2014) Amaury Pupo et al.   Channels

HV1 Acts as a Sodium Sensor and Promotes Superoxide Production in Medullary Thick Ascending Limb of Dahl Salt-Sensitive Rats

(2014) Chunhua Jin et al.   HYPERTENSION

Tracking S4 movement by gating pore currents in the bacterial sodium channel NaChBac

(2014) Tamer M. Gamal El-Din et al.   JOURNAL OF GENERAL PHYSIOLOGY

Hv1 proton channels differentially regulate the pH of neutrophil and macrophage phagosomes by sustaining the production of phagosomal ROS that inhibit the delivery of vacuolar ATPases

(2014) Antoun El Chemaly et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Hydrated Excess Protons Can Create Their Own Water Wires

(2014) Yuxing Peng et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain

(2014) Qufei Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

X-ray crystal structure of voltage-gated proton channel

(2014) Kohei Takeshita et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Enhanced activation of an amino-terminally truncated isoform of the voltage-gated proton channel HVCN1 enriched in malignant B cells

(2014) Elayne Hondares et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiscale simulation reveals a multifaceted mechanism of proton permeation through the influenza A M2 proton channel

(2014) Ruibin Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Moving gating charges through the gating pore in a Kv channel voltage sensor

(2014) J. J. Lacroix et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular determinants of Hv1 proton channel inhibition by guanidine derivatives

(2014) Liang Hong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping of sites facing aqueous environment of voltage-gated proton channel at resting state: A study with PEGylation protection

(2013) Tatsuki Kurokawa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Activation and Proton Transport Mechanism in Influenza A M2 Channel

(2013) Chenyu Wei et al.   BIOPHYSICAL JOURNAL

Proton channel HVCN1 is required for effector functions of mouse eosinophils

(2013) Xiang Zhu et al.   BMC IMMUNOLOGY

Peregrination of the selectivity filter delineates the pore of the human voltage-gated proton channel hHV1

(2013) Deri Morgan et al.   JOURNAL OF GENERAL PHYSIOLOGY

Construction and validation of a homology model of the human voltage-gated proton channel hHV1

(2013) Kethika Kulleperuma et al.   JOURNAL OF GENERAL PHYSIOLOGY

Molecular mechanism of voltage sensing in voltage-gated proton channels

(2013) Carlos Gonzalez et al.   JOURNAL OF GENERAL PHYSIOLOGY

Proton transfer reactions and hydrogen-bond networks in protein environments

(2013) H. Ishikita et al.   Journal of the Royal Society Interface

Functions of the hydrophilic channels in protonmotive cytochrome c oxidase

(2013) P. R. Rich et al.   Journal of the Royal Society Interface

Philosophy of voltage-gated proton channels

(2013) T. E. DeCoursey et al.   Journal of the Royal Society Interface

Voltage-Sensing Domain of Voltage-Gated Proton Channel Hv1 Shares Mechanism of Block with Pore Domains

(2013) Liang Hong et al.   NEURON

Voltage-Gated Proton Channels: Molecular Biology, Physiology, and Pathophysiology of the HV Family

(2013) Thomas E. DeCoursey   PHYSIOLOGICAL REVIEWS

Hydrophobic plug functions as a gate in voltage-gated proton channels

(2013) A. Chamberlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinicopathological and Biological Significance of Human Voltage-gated Proton Channel Hv1 Protein Overexpression in Breast Cancer

(2012) Yifan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NOX5 in Human Spermatozoa

(2012) Boris Musset et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The voltage-gated proton channel Hv1 enhances brain damage from ischemic stroke

(2012) Long-Jun Wu et al.   NATURE NEUROSCIENCE

Tracking a complete voltage-sensor cycle with metal-ion bridges

(2012) U. Henrion et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gating pore currents and the resting state of Nav1.4 voltage sensor domains

(2012) P. Gosselin-Badaroudine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for proton conduction and inhibition by the influenza M2 protein

(2012) Mei Hong et al.   PROTEIN SCIENCE

The cytoplasmic coiled-coil mediates cooperative gating temperature sensitivity in the voltage-gated H+ channel Hv1

(2012) Yuichiro Fujiwara et al.   Nature Communications

Subunit III-depleted cytochrome c oxidase provides insight into the process of proton uptake by proteins

(2011) Lakshman Varanasi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Water wires in atomistic models of the Hv1 proton channel

(2011) Mona L. Wood et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

R1 in the Shaker S4 occupies the gating charge transfer center in the resting state

(2011) Meng-chin A. Lin et al.   JOURNAL OF GENERAL PHYSIOLOGY

Enhancement of Proton Conductance by Mutations of the Selectivity Filter of Aquaporin-1

(2011) Hui Li et al.   JOURNAL OF MOLECULAR BIOLOGY

Aspartate 112 is the selectivity filter of the human voltage-gated proton channel

(2011) Boris Musset et al.   NATURE

Voltage-gated proton channel in a dinoflagellate

(2011) S. M. E. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for gating charge movement in the voltage sensor of a sodium channel

(2011) V. Yarov-Yarovoy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Voltage-Gated H+ Channel Underlying pH Homeostasis in Calcifying Coccolithophores

(2011) Alison R. Taylor et al.   PLOS BIOLOGY

Functional reconstitution of influenza A M2(22–62)

(2010) Emily Peterson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Calculation of the Gating Charge for the Kv1.2 Voltage-Activated Potassium Channel

(2010) Fatemeh Khalili-Araghi et al.   BIOPHYSICAL JOURNAL

Acid Extrusion from Human Spermatozoa Is Mediated by Flagellar Voltage-Gated Proton Channel

(2010) Polina V. Lishko et al.   CELL

Oligomerization of the voltage gated proton channel

(2010) Boris Musset et al.   Channels

Function of the HVCN1 proton channel in airway epithelia and a naturally occurring mutation, M91T

(2010) David Iovannisci et al.   JOURNAL OF GENERAL PHYSIOLOGY

State-dependent electrostatic interactions of S4 arginines with E1 in S2 during Kv7.1 activation

(2010) Dick Wu et al.   JOURNAL OF GENERAL PHYSIOLOGY

Zinc inhibition of monomeric and dimeric proton channels suggests cooperative gating

(2010) Boris Musset et al.   JOURNAL OF PHYSIOLOGY-LONDON

HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species

(2010) Melania Capasso et al.   NATURE IMMUNOLOGY

An aqueous H+ permeation pathway in the voltage-gated proton channel Hv1

(2010) I Scott Ramsey et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ion Channel Voltage Sensors: Structure, Function, and Pathophysiology

(2010) William A. Catterall   NEURON

Voltage-Gated Proton Channels Find Their Dream Job Managing the Respiratory Burst in Phagocytes

(2010) Thomas E. DeCoursey   PHYSIOLOGY

Proton and cation transport activity of the M2 proton channel from influenza A virus

(2010) T. Leiding et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insight into the Mechanism of the Influenza A Proton Channel from a Structure in a Lipid Bilayer

(2010) M. Sharma et al.   SCIENCE

A Gating Charge Transfer Center in Voltage Sensors

(2010) X. Tao et al.   SCIENCE

Identification of Thr29as a Critical Phosphorylation Site That Activates the Human Proton ChannelHvcn1in Leukocytes

(2009) Boris Musset et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification

(2009) Antoun El Chemaly et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Functional Reconstitution of Purified Human Hv1 H+ Channels

(2009) Seok-Yong Lee et al.   JOURNAL OF MOLECULAR BIOLOGY

Strong cooperativity between subunits in voltage-gated proton channels

(2009) Carlos Gonzalez et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The opening of the two pores of the Hv1 voltage-gated proton channel is tuned by cooperativity

(2009) Francesco Tombola et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis

(2009) D. Morgan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functionality of the voltage-gated proton channel truncated in S4

(2009) S. Sakata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The intimate and mysterious relationship between proton channels and NADPH oxidase

(2008) Boris Musset et al.   FEBS LETTERS

Cytochrome c oxidase: exciting progress and remaining mysteries

(2008) Peter Brzezinski et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Voltage-gated proton channels: what's next?

(2008) Thomas E. DeCoursey   JOURNAL OF PHYSIOLOGY-LONDON

Detailed comparison of expressed and native voltage-gated proton channel currents

(2008) B. Musset et al.   JOURNAL OF PHYSIOLOGY-LONDON

Sensing voltage across lipid membranes

(2008) Kenton J. Swartz   NATURE

Extent of Voltage Sensor Movement during Gating of Shaker K+ Channels

(2008) David J. Posson et al.   NEURON

A Common Pathway for Charge Transport through Voltage-Sensing Domains

(2008) Baron Chanda et al.   NEURON

The Voltage-Gated Proton Channel Hv1 Has Two Pores, Each Controlled by One Voltage Sensor

(2008) Francesco Tombola et al.   NEURON

A pH-stabilizing role of voltage-gated proton channels in IgE-mediated activation of human basophils

(2008) B. Musset et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multimeric nature of voltage-gated proton channels

(2008) Hans P. Koch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dimeric subunit stoichiometry of the human voltage-dependent proton channel Hv1

(2008) S.-Y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proton Transport through Influenza A Virus M2 Protein Reconstituted in Vesicles

(2007) J. Craig Moffat et al.   BIOPHYSICAL JOURNAL