Glia-Derived Extracellular Vesicles in Parkinson’s Disease

Parkinson's disease, aging and adult neurogenesis: Wnt/β‐catenin signalling as the key to unlock the mystery of endogenous brain repair

(2020) Bianca Marchetti et al.   AGING CELL

Astrocyte-Derived Exosomal microRNA miR-200a-3p Prevents MPP+-Induced Apoptotic Cell Death Through Down-Regulation of MKK4

(2020) Norshalena Shakespear et al.   NEUROCHEMICAL RESEARCH

Metabolic Regulation of Glial Phenotypes: Implications in Neuron–Glia Interactions and Neurological Disorders

(2020) Ruqayya Afridi et al.   Frontiers in Cellular Neuroscience

Potential Roles of Exosomes in Parkinson’s Disease: From Pathogenesis, Diagnosis, and Treatment to Prognosis

(2020) Haiyang Yu et al.   Frontiers in Cell and Developmental Biology

A longitudinal study on α‐synuclein in plasma neuronal exosomes as a biomarker for Parkinson’s disease development and progression

(2020) M. Niu et al.   EUROPEAN JOURNAL OF NEUROLOGY

Boosting Antioxidant Self-defenses by Grafting Astrocytes Rejuvenates the Aged Microenvironment and Mitigates Nigrostriatal Toxicity in Parkinsonian Brain via an Nrf2-Driven Wnt/β-Catenin Prosurvival Axis

(2020) Maria Francesca Serapide et al.   Frontiers in Aging Neuroscience

Extracellular Vesicles Secreted by Astroglial Cells Transport Apolipoprotein D to Neurons and Mediate Neuronal Survival Upon Oxidative Stress

(2019) Raquel Pascua-Maestro et al.   Frontiers in Cellular Neuroscience

Mesenchymal Stem Cells-derived Exosomes: A New Possible Therapeutic Strategy for Parkinson’s Disease?

(2019) Helena Vilaça-Faria et al.   Cells

Intranasal Administration of Extracellular Vesicles Derived from Human Teeth Stem Cells Improve Motor Symptoms and Normalize Tyrosine Hydroxylase Expression in the Substantia Nigra and Striatum of the 6-Hydroxydopamine-Treated Rats

(2019) Karīna Narbute et al.   Stem Cells Translational Medicine

Microglia as modulators of exosomal alpha-synuclein transmission

(2019) Yun Xia et al.   Cell Death & Disease

Involvement of exosomes in dopaminergic neurodegeneration by microglial activation in midbrain slice cultures

(2019) Reiho Tsutsumi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Parkinson's disease age at onset genome‐wide association study: Defining heritability, genetic loci, and α‐synuclein mechanisms

(2019) Cornelis Blauwendraat et al.   MOVEMENT DISORDERS

Microglia-mediated neuroinflammation in neurodegenerative diseases

(2019) Charannya Sozheesvari Subhramanyam et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Alpha-synuclein structure and Parkinson’s disease – lessons and emerging principles

(2019) Richard M. Meade et al.   Molecular Neurodegeneration

Cell therapy for Parkinson's disease: Why it doesn't work every time

(2019) Timothy J. Collier et al.   MOVEMENT DISORDERS

Insight into the Role of Extracellular Vesicles in Lysosomal Storage Disorders

(2019) Brunella Tancini et al.   Genes

Overview of Extracellular Vesicles, Their Origin, Composition, Purpose, and Methods for Exosome Isolation and Analysis

(2019) Laura M. Doyle et al.   Cells

The multiple roles of exosomes in Parkinson's disease: an overview

(2019) Chiara Porro et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Systemic Exosomal Delivery of shRNA Minicircles Prevents Parkinsonian Pathology

(2019) María Izco et al.   MOLECULAR THERAPY

Extracellular microvesicles-derived from microglia treated with unaggregated α-synuclein attenuate mitochondrial fission and toxicity-induced by Parkinsonian toxin MPP+

(2019) Na Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Serum secreted miR-137-containing exosomes affects oxidative stress of neurons by regulating OXR1 in Parkinson’s disease

(2019) Yan Jiang et al.   BRAIN RESEARCH

Exosomes From Astrocyte Processes: Signaling to Neurons

(2019) Arianna Venturini et al.   Frontiers in Pharmacology

Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration

(2018) Megan F. Duffy et al.   Journal of Neuroinflammation

Environmental neurotoxicant manganese regulates exosome-mediated extracellular miRNAs in cell culture model of Parkinson's disease: Relevance to α-synuclein misfolding in metal neurotoxicity

(2018) Dilshan S. Harischandra et al.   NEUROTOXICOLOGY

Functional dissection of astrocyte-secreted proteins: Implications in brain health and diseases

(2018) Mithilesh Kumar Jha et al.   PROGRESS IN NEUROBIOLOGY

Neural Stem Cell Grafts Promote Astroglia-Driven Neurorestoration in the Aged Parkinsonian Brain via Wnt/β-Catenin Signaling

(2018) Francesca L'episcopo et al.   STEM CELLS

An Inflammation-Centric View of Neurological Disease: Beyond the Neuron

(2018) Stephen D. Skaper et al.   Frontiers in Cellular Neuroscience

TNFα and IL-1β modify the miRNA cargo of astrocyte shed extracellular vesicles to regulate neurotrophic signaling in neurons

(2018) Amrita Datta Chaudhuri et al.   Cell Death & Disease

Designer exosomes produced by implanted cells intracerebrally deliver therapeutic cargo for Parkinson’s disease treatment

(2018) Ryosuke Kojima et al.   Nature Communications

Microglia Polarization, Gene-Environment Interactions and Wnt/β-Catenin Signaling: Emerging Roles of Glia-Neuron and Glia-Stem/Neuroprogenitor Crosstalk for Dopaminergic Neurorestoration in Aged Parkinsonian Brain

(2018) Francesca L'Episcopo et al.   Frontiers in Aging Neuroscience

On Cell Loss and Selective Vulnerability of Neuronal Populations in Parkinson's Disease

(2018) Nicolas Giguère et al.   Frontiers in Neurology

Dopamine-loaded blood exosomes targeted to brain for better treatment of Parkinson's disease

(2018) Mengke Qu et al.   JOURNAL OF CONTROLLED RELEASE

Therapeutic strategies for Parkinson disease: beyond dopaminergic drugs

(2018) Delphine Charvin et al.   NATURE REVIEWS DRUG DISCOVERY

Parkinson’s Disease: Biomarkers, Treatment, and Risk Factors

(2018) Fatemeh N. Emamzadeh et al.   Frontiers in Neuroscience

Secretion and Uptake of α-Synuclein Via Extracellular Vesicles in Cultured Cells

(2018) Gabriel Gustafsson et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Immune system responses in Parkinson's disease: Early and dynamic

(2018) Malú G. Tansey et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Wnt/β-Catenin Signaling Pathway Governs a Full Program for Dopaminergic Neuron Survival, Neurorescue and Regeneration in the MPTP Mouse Model of Parkinson’s Disease

(2018) Bianca Marchetti   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pathogenesis-targeted therapeutic strategies in Parkinson's disease

(2018) Joseph Jankovic   MOVEMENT DISORDERS

Quantification of brain-derived extracellular vesicles in plasma as a biomarker to diagnose Parkinson's and related diseases

(2018) Takuma Ohmichi et al.   PARKINSONISM & RELATED DISORDERS

Synaptic, Mitochondrial, and Lysosomal Dysfunction in Parkinson’s Disease

(2018) Maria Nguyen et al.   TRENDS IN NEUROSCIENCES

New Perspectives on Roles of Alpha-Synuclein in Parkinson’s Disease

(2018) Guoxin Zhang et al.   Frontiers in Aging Neuroscience

Compensatory mechanisms in Parkinson's disease: Circuits adaptations and role in disease modification

(2017) Javier Blesa et al.   EXPERIMENTAL NEUROLOGY

microRNAs in Parkinson’s Disease: From Pathogenesis to Novel Diagnostic and Therapeutic Approaches

(2017) Loredana Leggio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Prolonged Dysfunction of Astrocytes and Activation of Microglia Accelerate Degeneration of Dopaminergic Neurons in the Rat Substantia Nigra and Block Compensation of Early Motor Dysfunction Induced by 6-OHDA

(2017) Katarzyna Kuter et al.   MOLECULAR NEUROBIOLOGY

Aging and Parkinson's disease: Different sides of the same coin?

(2017) Timothy J. Collier et al.   MOVEMENT DISORDERS

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

(2017) J.A. Obeso et al.   MOVEMENT DISORDERS

MicroRNA biomarkers of Parkinson’s disease in serum exosome-like microvesicles

(2017) Xiang-Yang Cao et al.   NEUROSCIENCE LETTERS

Combined LRRK2 mutation, aging and chronic low dose oral rotenone as a model of Parkinson’s disease

(2017) Hui-Fang Liu et al.   Scientific Reports

Cell Biology and Pathophysiology of α-Synuclein

(2017) Jacqueline Burré et al.   Cold Spring Harbor Perspectives in Medicine

Targeting Microglial Activation States as a Therapeutic Avenue in Parkinson’s Disease

(2017) Sudhakar R. Subramaniam et al.   Frontiers in Aging Neuroscience

The MPTP Story

(2017) J. William Langston   Journal of Parkinsons Disease

A Refined Bead-Free Method to Identify Astrocytic Exosomes in Primary Glial Cultures and Blood Plasma

(2017) Cory M. Willis et al.   Frontiers in Neuroscience

Parkinson disease

(2017) Werner Poewe et al.   Nature Reviews Disease Primers

Astrocytes as secretory cells of the central nervous system: idiosyncrasies of vesicular secretion

(2016) A. Verkhratsky et al.   EMBO JOURNAL

Focus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer’s and Parkinson’s Disease

(2016) Laura Vella et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Astrocyte scar formation aids central nervous system axon regeneration

(2016) Mark A. Anderson et al.   NATURE

The Incidence of Parkinson's Disease: A Systematic Review and Meta-Analysis

(2016) Lauren Hirsch et al.   NEUROEPIDEMIOLOGY

Microglia Priming with Aging and Stress

(2016) Anzela Niraula et al.   NEUROPSYCHOPHARMACOLOGY

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Editorial: Glial Cells: Managers of Neuro-Immunity

(2016) Carlos Barcia et al.   Frontiers in Cellular Neuroscience

Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke

(2016) Gergely Szalay et al.   Nature Communications

Exosomes in Parkinson’s Disease

(2016) Xiaoqing Wu et al.   Neuroscience Bulletin

IGF-1 protects dopamine neurons against oxidative stress: association with changes in phosphokinases

(2016) Amina El Ayadi et al.   EXPERIMENTAL BRAIN RESEARCH

A Case-Control Association Study of RANTES (-28C>G) Polymorphism as a Risk Factor for Parkinson’s Disease in Isparta, Turkey

(2016) Nilufer Sahin-Calapoglu et al.   Parkinsons Disease

Extracellular Vesicles and a Novel Form of Communication in the Brain

(2016) Manuela Basso et al.   Frontiers in Neuroscience

Age-dependent defects of alpha-synuclein oligomer uptake in microglia and monocytes

(2015) Corinna Bliederhaeuser et al.   ACTA NEUROPATHOLOGICA

Parkinson's disease as a result of aging

(2015) Manuel Rodriguez et al.   AGING CELL

Roles of microglia in brain development, tissue maintenance and repair

(2015) Mackenzie A. Michell-Robinson et al.   BRAIN

Exosomes from dental pulp stem cells rescue human dopaminergic neurons from 6-hydroxy-dopamine–induced apoptosis

(2015) Akvilė Jarmalavičiūtė et al.   CYTOTHERAPY

Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease

(2015) Lauren E. Tebay et al.   FREE RADICAL BIOLOGY AND MEDICINE

MicroRNA-Let-7a regulates the function of microglia in inflammation

(2015) Kyoung Joo Cho et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The endosomal pathway in Parkinson's disease

(2015) Rebecca M. Perrett et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Inflammation is genetically implicated in Parkinson’s disease

(2015) N. Dzamko et al.   NEUROSCIENCE

Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease

(2015) YaXing Gui et al.   Oncotarget

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Macrophage Antigen Complex-1 Mediates Reactive Microgliosis and Progressive Dopaminergic Neurodegeneration in the MPTP Model of Parkinson's Disease

(2014) X. Hu et al.   JOURNAL OF IMMUNOLOGY

Proteomic analysis of cerebrospinal fluid extracellular vesicles: A comprehensive dataset

(2014) Davide Chiasserini et al.   Journal of Proteomics

Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: future therapeutic perspectives

(2014) Anthony H V Schapira et al.   LANCET

Role of synucleins in traumatic brain injury — An experimental in vitro and in vivo study in mice

(2014) Irina Surgucheva et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Exosomes as a Nanodelivery System: a Key to the Future of Neuromedicine?

(2014) Arian Aryani et al.   MOLECULAR NEUROBIOLOGY

Systemic exosomal siRNA delivery reduced alpha-synuclein aggregates in brains of transgenic mice

(2014) J. Mark Cooper et al.   MOVEMENT DISORDERS

Redundant dopaminergic activity may enable compensatory axonal sprouting in Parkinson disease

(2014) D. Arkadir et al.   NEUROLOGY

Reactive Gliosis and the Multicellular Response to CNS Damage and Disease

(2014) Joshua E. Burda et al.   NEURON

Multifaceted effects of oligodendroglial exosomes on neurons: impact on neuronal firing rate, signal transduction and gene regulation

(2014) D. Frohlich et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

GDNF-Transfected Macrophages Produce Potent Neuroprotective Effects in Parkinson's Disease Mouse Model

(2014) Yuling Zhao et al.   PLoS One

Location Is Everything: let-7b microRNA and TLR7 Signaling Results in a Painful TRP

(2014) C. W. Winkler et al.   Science Signaling

Wnt/β-Catenin Signaling Is Required to Rescue Midbrain Dopaminergic Progenitors and Promote Neurorepair in Ageing Mouse Model of Parkinson's Disease

(2014) Francesca L'Episcopo et al.   STEM CELLS

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease

(2014) Ernest Arenas   Journal of Molecular Cell Biology

Targeting Wnt signaling at the neuroimmune interface for dopaminergic neuroprotection/repair in Parkinson's disease

(2014) Francesca L'Episcopo et al.   Journal of Molecular Cell Biology

Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression

(2014) Giulia E. Tyzack et al.   Nature Communications

Activated astrocytes enhance the dopaminergic differentiation of stem cells and promote brain repair through bFGF

(2014) Fan Yang et al.   Nature Communications

New α- and γ-synuclein immunopathological lesions in human brain

(2014) Irina Surgucheva et al.   Acta Neuropathologica Communications

Neuroimmunological Processes in Parkinson's Disease and their Relation to α-Synuclein: Microglia as the Referee between Neuronal Processes and Peripheral Immunity

(2013) Vanesa Sanchez-Guajardo et al.   ASN Neuro

Uncovering novel actors in astrocyte-neuron crosstalk in Parkinson's disease: the Wnt/β-catenin signaling cascade as the common final pathway for neuroprotection and self-repair

(2013) Bianca Marchetti et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Pink1 deficiency attenuates astrocyte proliferation through mitochondrial dysfunction, reduced akt and increased p38 mapk activation, and downregulation of egfr

(2013) Insup Choi et al.   GLIA

Aging-Induced Nrf2-ARE Pathway Disruption in the Subventricular Zone Drives Neurogenic Impairment in Parkinsonian Mice via PI3K-Wnt/ -Catenin Dysregulation

(2013) F. L'Episcopo et al.   JOURNAL OF NEUROSCIENCE

The Function of α-Synuclein

(2013) Jacob T. Bendor et al.   NEURON

Exosomes of BV-2 cells induced by alpha-synuclein: Important mediator of neurodegeneration in PD

(2013) Chongwang Chang et al.   NEUROSCIENCE LETTERS

Triggering of Inflammasome by Aggregated α–Synuclein, an Inflammatory Response in Synucleinopathies

(2013) Gaia Codolo et al.   PLoS One

Specific Transfection of Inflamed Brain by Macrophages: A New Therapeutic Strategy for Neurodegenerative Diseases

(2013) Matthew J. Haney et al.   PLoS One

Identification and Rescue of  -Synuclein Toxicity in Parkinson Patient-Derived Neurons

(2013) C. Y. Chung et al.   SCIENCE

Microglia and macrophages of the central nervous system: the contribution of microglia priming and systemic inflammation to chronic neurodegeneration

(2013) V. Hugh Perry et al.   Seminars in Immunopathology

Wnt your brain be inflamed? Yes, it Wnt!

(2013) Bianca Marchetti et al.   TRENDS IN MOLECULAR MEDICINE

Wnt1-regulated genetic networks in midbrain dopaminergic neuron development

(2013) W. Wurst et al.   Journal of Molecular Cell Biology

Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte–Neuron Communication

(2013) Carsten Frühbeis et al.   PLOS BIOLOGY

Glia as a Turning Point in the Therapeutic Strategy of Parkinsons Disease

(2012) Francesca L'Episcopo et al.   CNS & Neurological Disorders-Drug Targets

Astrocytes and disease: a neurodevelopmental perspective

(2012) A. V. Molofsky et al.   GENES & DEVELOPMENT

Plasticity of Subventricular Zone Neuroprogenitors in MPTP (1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine) Mouse Model of Parkinson's Disease Involves Cross Talk between Inflammatory and Wnt/ -Catenin Signaling Pathways: Functional Consequences for Neuroprotection and Repair

(2012) F. L'Episcopo et al.   JOURNAL OF NEUROSCIENCE

Inflammation and α-Synuclein’s Prion-like Behavior in Parkinson's Disease—Is There a Link?

(2012) Carla M. Lema Tomé et al.   MOLECULAR NEUROBIOLOGY

Pathogenesis of Parkinson's disease

(2012) Etienne C. Hirsch et al.   MOVEMENT DISORDERS

Lysosome-dependent pathways as a unifying theme in Parkinson's disease

(2012) George K. Tofaris   MOVEMENT DISORDERS

Gene–environment interactions in Parkinson's disease: Specific evidence in humans and mammalian models

(2012) Jason R. Cannon et al.   NEUROBIOLOGY OF DISEASE

Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation

(2011) Mireille Bélanger et al.   Cell Metabolism

Neuroinflammation and α-Synuclein Dysfunction Potentiate Each Other, Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson’s Disease

(2011) Hui-Ming Gao et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Synapsin I Is an Oligomannose-Carrying Glycoprotein, Acts As an Oligomannose-Binding Lectin, and Promotes Neurite Outgrowth and Neuronal Survival When Released via Glia-Derived Exosomes

(2011) S. Wang et al.   JOURNAL OF NEUROSCIENCE

A Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection

(2011) Francesca L'Episcopo et al.   Molecular Neurodegeneration

Alpha-synuclein release by neurons activates the inflammatory response in a microglial cell line

(2011) Lydia Alvarez-Erviti et al.   NEUROSCIENCE RESEARCH

Structural Remodeling of Astrocytes in the Injured CNS

(2011) Daniel Sun et al.   NEUROSCIENTIST

Gene–environment interactions: Key to unraveling the mystery of Parkinson's disease

(2011) Hui-Ming Gao et al.   PROGRESS IN NEUROBIOLOGY

Switching the Microglial Harmful Phenotype Promotes Lifelong Restoration of Subtantia Nigra Dopaminergic Neurons from Inflammatory Neurodegeneration in Aged Mice

(2011) Francesca L'Episcopo et al.   REJUVENATION RESEARCH

Interaction between -Synuclein and Other Proteins in Neurodegenerative Disorders

(2011) Kurt A. Jellinger   TheScientificWorldJOURNAL

Ageing, neurodegeneration and Parkinson's disease

(2010) J. V. Hindle   AGE AND AGEING

Age-specific progression of nigrostriatal dysfunction in Parkinson's disease

(2010) Raúl de la Fuente-Fernández et al.   ANNALS OF NEUROLOGY

Statins Promote the Degradation of Extracellular Amyloid β-Peptide by Microglia via Stimulation of Exosome-associated Insulin-degrading Enzyme (IDE) Secretion

(2010) Irfan Y. Tamboli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies

(2010) He-Jin Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global microRNA Expression Profiling of Caenorhabditis elegans Parkinson's Disease Models

(2010) Suvi Asikainen et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Combining nitric oxide release with anti-inflammatory activity preserves nigrostriatal dopaminergic innervation and prevents motor impairment in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

(2010) Francesca L'Episcopo et al.   Journal of Neuroinflammation

Cell-Produced  -Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival

(2010) E. Emmanouilidou et al.   JOURNAL OF NEUROSCIENCE

Inflammation and Parkinson's disease pathogenesis

(2010) Serge Przedborski   MOVEMENT DISORDERS

Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function

(2010) eMalick G. Njie et al.   NEUROBIOLOGY OF AGING

Reactive astrocytes and Wnt/β-catenin signaling link nigrostriatal injury to repair in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

(2010) F. L'Episcopo et al.   NEUROBIOLOGY OF DISEASE

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

IL-1β enhances the antibacterial activity of astrocytes by activation of NF-κB

(2009) Yulei Xia et al.   GLIA

Neuroinflammation in Parkinson's disease: a target for neuroprotection?

(2009) Etienne C Hirsch et al.   LANCET NEUROLOGY

Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention

(2009) Malú G. Tansey et al.   NEUROBIOLOGY OF DISEASE

Triggering endogenous neuroprotective processes through exercise in models of dopamine deficiency

(2009) Michael J. Zigmond et al.   PARKINSONISM & RELATED DISORDERS

A dual-hit animal model for age-related parkinsonism

(2009) Heather A. Boger et al.   PROGRESS IN NEUROBIOLOGY

Age-related changes in dopamine transporters and accumulation of 3-nitrotyrosine in rhesus monkey midbrain dopamine neurons: Relevance in selective neuronal vulnerability to degeneration

(2008) N. M. Kanaan et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE

Astrocyte-secreted GDNF and glutathione antioxidant system protect neurons against 6OHDA cytotoxicity

(2008) Jagdeep K. Sandhu et al.   NEUROBIOLOGY OF DISEASE

The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease

(2008) Ben A. Barres   NEURON

Induction of Neurogenesis in Nonconventional Neurogenic Regions of the Adult Central Nervous System by Niche Astrocyte-Produced Signals

(2008) Jianwei Jiao et al.   STEM CELLS

Inflammation as a causative factor in the aetiology of Parkinson's disease

(2007) P S Whitton   BRITISH JOURNAL OF PHARMACOLOGY

Glial reactions in Parkinson's disease

(2007) Patrick L. McGeer et al.   MOVEMENT DISORDERS