Wnt/β-Catenin Signaling Is Required to Rescue Midbrain Dopaminergic Progenitors and Promote Neurorepair in Ageing Mouse Model of Parkinson's Disease

Regulating Wnt signaling: a strategy to prevent neurodegeneration and induce regeneration

(2014) K. Harvey et al.   Journal of Molecular Cell Biology

Dysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases

(2014) S. A. Purro et al.   Journal of Molecular Cell Biology

Wnt signaling in the nervous system and in Alzheimer's disease

(2014) N. C. Inestrosa et al.   Journal of Molecular Cell Biology

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease

(2014) Ernest Arenas   Journal of Molecular Cell Biology

Targeting Wnt signaling at the neuroimmune interface for dopaminergic neuroprotection/repair in Parkinson's disease

(2014) Francesca L'Episcopo et al.   Journal of Molecular Cell Biology

Therapeutic prospects for Parkinson disease

(2013) C. Warren Olanow et al.   ANNALS OF NEUROLOGY

Loss of Dickkopf-1 Restores Neurogenesis in Old Age and Counteracts Cognitive Decline

(2013) Désirée R.M. Seib et al.   Cell Stem Cell

Uncovering novel actors in astrocyte-neuron crosstalk in Parkinson's disease: the Wnt/β-catenin signaling cascade as the common final pathway for neuroprotection and self-repair

(2013) Bianca Marchetti et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Induced neural stem cells (iNSCs) in neurodegenerative diseases

(2013) Andreas Hermann et al.   JOURNAL OF NEURAL TRANSMISSION

Interactions of Wnt/ -Catenin Signaling and Sonic Hedgehog Regulate the Neurogenesis of Ventral Midbrain Dopamine Neurons

(2013) M. Tang et al.   JOURNAL OF NEUROSCIENCE

Aging-Induced Nrf2-ARE Pathway Disruption in the Subventricular Zone Drives Neurogenic Impairment in Parkinsonian Mice via PI3K-Wnt/ -Catenin Dysregulation

(2013) F. L'Episcopo et al.   JOURNAL OF NEUROSCIENCE

Improved Cell Therapy Protocols for Parkinson's Disease Based on Differentiation Efficiency and Safety of hESC-, hiPSC-, and Non-Human Primate iPSC-Derived Dopaminergic Neurons

(2013) Maria Sundberg et al.   STEM CELLS

Ryk, a Receptor Regulating Wnt5a-Mediated Neurogenesis and Axon Morphogenesis of Ventral Midbrain Dopaminergic Neurons

(2013) Brette D. Blakely et al.   STEM CELLS AND DEVELOPMENT

Wnt your brain be inflamed? Yes, it Wnt!

(2013) Bianca Marchetti et al.   TRENDS IN MOLECULAR MEDICINE

Wnt1-regulated genetic networks in midbrain dopaminergic neuron development

(2013) W. Wurst et al.   Journal of Molecular Cell Biology

The regulation and deregulation of Wnt signaling by PARK genes in health and disease

(2013) D. C. Berwick et al.   Journal of Molecular Cell Biology

Wnt/ -catenin signaling in midbrain dopaminergic neuron specification and neurogenesis

(2013) M. Joksimovic et al.   Journal of Molecular Cell Biology

Modulating Wnt signaling to improve cell replacement therapy for Parkinson's disease

(2013) C. L. Parish et al.   Journal of Molecular Cell Biology

Clinical application of stem cell therapy in Parkinson's disease

(2012) Marios Politis et al.   BMC Medicine

Physical activity and environmental enrichment regulate the generation of neural precursors in the adult mouse substantia nigra in a dopamine-dependent manner

(2012) Philipp Klaissle et al.   BMC NEUROSCIENCE

Neurogenic potential of progenitor cells isolated from postmortem human Parkinsonian brains

(2012) Shanshan Wang et al.   BRAIN RESEARCH

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Adult Neural Stem Cells Bridge Their Niche

(2012) Luis C. Fuentealba et al.   Cell Stem Cell

LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6

(2012) Daniel C. Berwick et al.   HUMAN MOLECULAR GENETICS

Plasticity of Subventricular Zone Neuroprogenitors in MPTP (1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine) Mouse Model of Parkinson's Disease Involves Cross Talk between Inflammatory and Wnt/ -Catenin Signaling Pathways: Functional Consequences for Neuroprotection and Repair

(2012) F. L'Episcopo et al.   JOURNAL OF NEUROSCIENCE

Attenuated response to methamphetamine sensitization and deficits in motor learning and memory after selective deletion of  -catenin in dopamine neurons

(2012) O. Diaz-Ruiz et al.   LEARNING & MEMORY

Cross-talk between neural stem cells and immune cells: the key to better brain repair?

(2012) Zaal Kokaia et al.   NATURE NEUROSCIENCE

Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions

(2012) Xiaojun Lian et al.   Nature Protocols

Nanotechnology—novel therapeutics for CNS disorders

(2012) Maya Srikanth et al.   Nature Reviews Neurology

Concordant Signaling Pathways Produced by Pesticide Exposure in Mice Correspond to Pathways Identified in Human Parkinson's Disease

(2012) Seema Gollamudi et al.   PLoS One

Glycogen Synthase Kinase-3 Inhibition Promotes Proliferation and Neuronal Differentiation of Human-Induced Pluripotent Stem Cell-Derived Neural Progenitors

(2012) Fereshteh Esfandiari et al.   STEM CELLS AND DEVELOPMENT

Generation of Regionally Specified Neural Progenitors and Functional Neurons from Human Embryonic Stem Cells under Defined Conditions

(2012) Agnete Kirkeby et al.   Cell Reports

Reduction in paracrine Wnt3 factors during aging causes impaired adult neurogenesis

(2011) Masahiro Okamoto et al.   FASEB JOURNAL

Reactive astrocytes and Wnt/β-catenin signaling link nigrostriatal injury to repair in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

(2010) F. L'Episcopo et al.   NEUROBIOLOGY OF DISEASE

Multiple roles of  -catenin in controlling the neurogenic niche for midbrain dopamine neurons

(2009) M. Tang et al.   DEVELOPMENT

Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model

(2009) Beate Winner et al.   EXPERIMENTAL NEUROLOGY

α-Synuclein contributes to GSK-3β-catalyzed Tau phosphorylation in Parkinson’s disease models

(2009) Tetyana Duka et al.   FASEB JOURNAL

Nurr1 Is Required for Maintenance of Maturing and Adult Midbrain Dopamine Neurons

(2009) B. Kadkhodaei et al.   JOURNAL OF NEUROSCIENCE

Restorative approaches in Parkinson's Disease: Which cell type wins the race?

(2009) Anne K. Meyer et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis

(2009) Tomoko Kuwabara et al.   NATURE NEUROSCIENCE

Involvment of Cytosolic and Mitochondrial GSK-3β in Mitochondrial Dysfunction and Neuronal Cell Death of MPTP/MPP+-Treated Neurons

(2009) Agnès Petit-Paitel et al.   PLoS One

Rostro-Caudal Gradual Loss of Cellular Diversity Within the Periventricular Regions of the Ventricular System

(2009) Andreas Hermann et al.   STEM CELLS

Review: Cellular repair strategies in Parkinson's disease

(2009) Beate Winner et al.   Therapeutic Advances in Neurological Disorders

Persistent inflammation alters the function of the endogenous brain stem cell compartment

(2008) Stefano Pluchino et al.   BRAIN

Identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors

(2008) Sonia Bonilla et al.   GLIA

Brain inflammation and adult neurogenesis: The dual role of microglia

(2008) C.T. Ekdahl et al.   NEUROSCIENCE

Wnt-mediated self-renewal of neural stem/progenitor cells

(2008) M. Y. S. Kalani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endogenous Regeneration in Parkinson's Disease: Do We NeedOrthotopicDopaminergic Neurogenesis?

(2008) Andreas Hermann et al.   STEM CELLS