Systemic exosomal siRNA delivery reduced alpha-synuclein aggregates in brains of transgenic mice

Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys

(2013) Ariadna Recasens et al.   ANNALS OF NEUROLOGY

Ser129D mutant alpha-synuclein induces earlier motor dysfunction while S129A results in distinctive pathology in a rat model of Parkinson's disease

(2013) Fabia Febbraro et al.   NEUROBIOLOGY OF DISEASE

Influence of microRNA deregulation on chaperone-mediated autophagy and α-synuclein pathology in Parkinson's disease

(2013) L Alvarez-Erviti et al.   Cell Death & Disease

Parkinson's Disease: Gene Therapies

(2013) P. G. Coune et al.   Cold Spring Harbor Perspectives in Medicine

Pathological  -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice

(2012) K. C. Luk et al.   SCIENCE

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Genetic Animal Models of Parkinson's Disease

(2010) Ted M. Dawson et al.   NEURON

A critical evaluation of current staging of α-synuclein pathology in Lewy body disorders

(2008) Kurt A. Jellinger   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

In vivo silencing of alpha-synuclein using naked siRNA

(2008) Jada Lewis et al.   Molecular Neurodegeneration

Near Complete Rescue of Experimental Parkinson’s Disease with Intravenous, Non-viral GDNF Gene Therapy

(2008) Yun Zhang et al.   PHARMACEUTICAL RESEARCH