Parkinson's disease age at onset genome‐wide association study: Defining heritability, genetic loci, and α‐synuclein mechanisms

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Variants in GBA , SNCA , and MAPT influence Parkinson disease risk, age at onset, and progression

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Polygenic risk of Parkinson disease is correlated with disease age at onset

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GBA deficiency promotes SNCA/α-synuclein accumulation through autophagic inhibition by inactivated PPP2A

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Impact of Parkinson's disease risk loci on age at onset

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Differential effects of severe vs mild GBA mutations on Parkinson disease

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GWAS of Longevity in CHARGE Consortium Confirms APOE and FOXO3 Candidacy

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Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

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LIMP-2 expression is critical for  -glucocerebrosidase activity and  -synuclein clearance

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Glucocerebrosidase depletion enhances cell-to-cell transmission of α-synuclein

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The Val158Met COMT polymorphism is a modifier of the age at onset in Parkinson's disease with a sexual dimorphism

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A large study reveals no association between APOE and Parkinson's disease

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Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies

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Cyclin-G-associated kinase modifies  -synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study

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Genome-wide association study reveals genetic risk underlying Parkinson's disease

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Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

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Worldwide frequency of G2019S LRRK2 mutation in Parkinson's disease: A systematic review

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Genomic investigation of α-synuclein multiplication and parkinsonism

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Mutations in GBA are associated with familial Parkinson disease susceptibility and age at onset

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Genotype-phenotype correlations between GBA mutations and Parkinson disease risk and onset

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