Biological Considerations in Scaling Up Therapeutic Cell Manufacturing
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Title
Biological Considerations in Scaling Up Therapeutic Cell Manufacturing
Authors
Keywords
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Journal
Frontiers in Pharmacology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-05-13
DOI
10.3389/fphar.2020.00654
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Note: Only part of the references are listed.- Polymer-based porous microcarriers as cell delivery systems for applications in bone and cartilage tissue engineering
- (2020) Zhihua Zhou et al. INTERNATIONAL MATERIALS REVIEWS
- IFNγ and TNFα synergistically induce apoptosis of mesenchymal stem/stromal cells via the induction of nitric oxide
- (2019) Xiaolei Li et al. Stem Cell Research & Therapy
- Human serum enhances the proliferative capacity and immunomodulatory property of MSCs derived from human placenta and umbilical cord
- (2019) Sermporn Thaweesapphithak et al. Stem Cell Research & Therapy
- Challenges for mesenchymal stromal cell therapies
- (2019) Ivan Martin et al. Science Translational Medicine
- Current understanding of the immunosuppressive properties of mesenchymal stromal cells
- (2019) Ligia Lins de Castro et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Apoptotic mesenchymal stromal cells induce prostaglandin E2 in monocytes: implications for the monitoring of mesenchymal stromal cells activity
- (2019) Tik Shing Cheung et al. HAEMATOLOGICA
- [Scalable Manufacturing of Human Mesenchymal Stromal Cells in the Vertical‐Wheel™ Bioreactor System: An Experimental and Economic Approach]
- (2019) Diogo Sousa Pinto et al. Biotechnology Journal
- The Pros and Cons of Mesenchymal Stem Cell-Based Therapies
- (2019) Aleksandra Musiał-Wysocka et al. CELL TRANSPLANTATION
- Attachment and detachment strategies in microcarrier-based cell culture technology: A comprehensive review
- (2019) Sorour Derakhti et al. Materials Science & Engineering C-Materials for Biological Applications
- Gaps in the knowledge of human platelet lysate as a cell culture supplement for cell therapy: A joint publication from the AABB and the International Society of Cell Therapy
- (2019) KAREN Bieback et al. CYTOTHERAPY
- Preparing for cell culture scale-out: establishing parity of bioreactor- and flask-expanded mesenchymal stromal cell cultures
- (2019) Ruud Das et al. Journal of Translational Medicine
- Multiplicity of Mesenchymal Stromal Cells: Finding the Right Route to Therapy
- (2019) Alison Wilson et al. Frontiers in Immunology
- Capturing the Fantastic Voyage of Monocytes Through Time and Space
- (2019) Ye Chean Teh et al. Frontiers in Immunology
- The effect of culture media on large-scale expansion and characteristic of adipose tissue-derived mesenchymal stromal cells
- (2019) Justyna Czapla et al. Stem Cell Research & Therapy
- Recent advances in the use of microcarriers for cell cultures and their ex vivo and in vivo applications
- (2019) Xiao-Yi Chen et al. BIOTECHNOLOGY LETTERS
- Differences between the Proliferative Effects of Human Platelet Lysate and Fetal Bovine Serum on Human Adipose-Derived Stem Cells
- (2019) Kakudo et al. Cells
- Manufacturing human mesenchymal stem cells at clinical scale: process and regulatory challenges
- (2018) Valentin Jossen et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Qualitative and quantitative demonstration of bead-to-bead transfer with bone marrow-derived human mesenchymal stem cells on microcarriers: Utilising the phenomenon to improve culture performance
- (2018) Qasim A. Rafiq et al. BIOCHEMICAL ENGINEERING JOURNAL
- Manufacturing mesenchymal stromal cells for the treatment of graft-versus-host disease: a survey amongst centers affiliated to the European Group of Blood and Marrow Transplantation
- (2018) Cristina Trento et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities
- (2018) Jacques Galipeau et al. Cell Stem Cell
- Collagenase Impacts the Quantity and Quality of Native Mesenchymal Stem/Stromal Cells Derived during Processing of Umbilical Cord Tissue
- (2018) Rouzbeh R. Taghizadeh et al. CELL TRANSPLANTATION
- Pooled human serum: A new culture supplement for bioreactor-based cell therapies. Preliminary results
- (2018) Sara Savelli et al. CYTOTHERAPY
- Immune modulation by apoptotic dental pulp stem cells in vivo
- (2018) Adam G Laing et al. Immunotherapy
- Immunomodulation By Therapeutic Mesenchymal Stromal Cells (MSC) Is Triggered Through Phagocytosis of MSC By Monocytic Cells
- (2018) Samantha F.H. de Witte et al. STEM CELLS
- Mechanically-sensitive miRNAs bias human mesenchymal stem cell fate via mTOR signalling
- (2018) Jessica E. Frith et al. Nature Communications
- Comparison of the Biological Characteristics of Mesenchymal Stem Cells Derived from the Human Placenta and Umbilical Cord
- (2018) Mingjun Wu et al. Scientific Reports
- Long-Term Maintenance of Human Pluripotent Stem Cells on cRGDfK-Presenting Synthetic Surfaces
- (2018) Jack W. Lambshead et al. Scientific Reports
- The cytokine secretion profile of mesenchymal stromal cells is determined by surface structure of the microenvironment
- (2018) Daniëlle G. Leuning et al. Scientific Reports
- Human platelet lysate in mesenchymal stromal cell expansion according to a GMP grade protocol: a cell factory experience
- (2018) Valentina Becherucci et al. Stem Cell Research & Therapy
- Apoptotic Cell-Derived Extracellular Vesicles: More Than Just Debris
- (2018) Sarah Caruso et al. Frontiers in Immunology
- Enhanced Immunosuppressive Properties of Human Mesenchymal Stem Cells Primed by Interferon-γ
- (2018) Dae Seong Kim et al. EBioMedicine
- Evaluation of Cartilage Specific Matrix Synthesis of Human Articular Chondrocytes after Extended Propagation on Microcarriers by Image Analysis
- (2018) Christiane Goepfert et al. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
- Allogeneic cell therapy manufacturing: process development technologies and facility design options
- (2017) Saeed Abbasalizadeh et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine
- (2017) Francisco Vizoso et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- VEGF secreted by mesenchymal stem cells mediates the differentiation of endothelial progenitor cells into endothelial cells via paracrine mechanisms
- (2017) Quanhu Ge et al. Molecular Medicine Reports
- Long-term growth comparison studies of FBS and FBS alternatives in six head and neck cell lines
- (2017) Chih-Yeu Fang et al. PLoS One
- Progress and challenges in large-scale expansion of human pluripotent stem cells
- (2017) Christina Kropp et al. PROCESS BIOCHEMISTRY
- Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation
- (2017) Antonio Galleu et al. Science Translational Medicine
- Natural killer cell-mediated immunosurveillance of human cancer
- (2017) Karl-Johan Malmberg et al. SEMINARS IN IMMUNOLOGY
- Effect of the Microenvironment on Mesenchymal Stem Cell Paracrine Signaling: Opportunities to Engineer the Therapeutic Effect
- (2017) Gina D. Kusuma et al. STEM CELLS AND DEVELOPMENT
- Mesenchymal stem cells inhibit T cell activation by releasing TGF-β1 from TGF-β1/GARP complex
- (2017) Jian Niu et al. Oncotarget
- Critical attributes of human early mesenchymal stromal cell-laden microcarrier constructs for improved chondrogenic differentiation
- (2017) Youshan Melissa Lin et al. Stem Cell Research & Therapy
- Xeno-Free Strategies for Safe Human Mesenchymal Stem/Stromal Cell Expansion: Supplements and Coatings
- (2017) M. Cimino et al. Stem Cells International
- Three-Dimensional Cell Cultures in Drug Discovery and Development
- (2017) Ye Fang et al. SLAS Discovery
- Characterisation of stresses on microcarriers in a stirred bioreactor
- (2016) J.D. Berry et al. APPLIED MATHEMATICAL MODELLING
- Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors
- (2016) Qasim A. Rafiq et al. Biotechnology Journal
- Stirred tank bioreactor culture combined with serum-/xenogeneic-free culture medium enables an efficient expansion of umbilical cord-derived mesenchymal stem/stromal cells
- (2016) Amanda Mizukami et al. Biotechnology Journal
- Biodegradable ECM-coated PCL microcarriers support scalable human early MSC expansion and in vivo bone formation
- (2016) Asha Shekaran et al. CYTOTHERAPY
- Immunomodulatory effects of mesenchymal stromal cells-derived exosome
- (2016) Wancheng Chen et al. IMMUNOLOGIC RESEARCH
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- (2016) Heather Owston et al. INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
- Microcarrier-based platforms for in vitro expansion and differentiation of human pluripotent stem cells in bioreactor culture systems
- (2016) Sara M. Badenes et al. JOURNAL OF BIOTECHNOLOGY
- Comparison of clinical grade human platelet lysates for cultivation of mesenchymal stromal cells from bone marrow and adipose tissue
- (2016) Morten Juhl et al. SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION
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- (2016) Raghavan Chinnadurai et al. STEM CELLS
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- (2016) Carolina Serena et al. STEM CELLS
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- (2016) Lindsay C. Davies et al. STEM CELLS
- Mitochondrial Transfer via Tunneling Nanotubes is an Important Mechanism by Which Mesenchymal Stem Cells Enhance Macrophage Phagocytosis in the In Vitro and In Vivo Models of ARDS
- (2016) Megan V. Jackson et al. STEM CELLS
- Inactivated Mesenchymal Stem Cells Maintain Immunomodulatory Capacity
- (2016) Franka Luk et al. STEM CELLS AND DEVELOPMENT
- Mesenchymal stem cells and immunomodulation: current status and future prospects
- (2016) F Gao et al. Cell Death & Disease
- Modulation of the Mesenchymal Stem Cell Secretome Using Computer-Controlled Bioreactors: Impact on Neuronal Cell Proliferation, Survival and Differentiation
- (2016) Fábio G. Teixeira et al. Scientific Reports
- Platelet lysate as a substitute for animal serum for the ex-vivo expansion of mesenchymal stem/stromal cells: present and future
- (2016) Giuseppe Astori et al. Stem Cell Research & Therapy
- Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors
- (2016) Qasim A. Rafiq et al. Biotechnology Journal
- Stirred tank bioreactor culture combined with serum-/xenogeneic-free culture medium enables an efficient expansion of umbilical cord-derived mesenchymal stem/stromal cells
- (2016) Amanda Mizukami et al. Biotechnology Journal
- Manufacturing of Human Umbilical Cord Mesenchymal Stromal Cells on Microcarriers in a Dynamic System for Clinical Use
- (2016) Florian Petry et al. Stem Cells International
- Human mesenchymal stromal cells exert HGF dependent cytoprotective effects in a human relevant pre-clinical model of COPD
- (2016) Helen Kennelly et al. Scientific Reports
- Human Mesenchymal stem cells program macrophage plasticity by altering their metabolic status via a PGE2-dependent mechanism
- (2016) Anoop Babu Vasandan et al. Scientific Reports
- Human mesenchymal stem cells - current trends and future prospective
- (2015) Imran Ullah et al. BIOSCIENCE REPORTS
- Production of oncolytic adenovirus and human mesenchymal stem cells in a single-use, Vertical-Wheel bioreactor system: Impact of bioreactor design on performance of microcarrier-based cell culture processes
- (2015) Marcos F. Q. Sousa et al. BIOTECHNOLOGY PROGRESS
- Immunoregulatory Effects of Mesenchymal Stem Cell-Derived Extracellular Vesicles on T Lymphocytes
- (2015) Andrea Del Fattore et al. CELL TRANSPLANTATION
- Mesenchymal stromal cells derived from various tissues: Biological, clinical and cryopreservation aspects
- (2015) Leah A. Marquez-Curtis et al. CRYOBIOLOGY
- Preparation, quality criteria, and properties of human blood platelet lysate supplements for ex vivo stem cell expansion
- (2015) Daniel Tzu-Bi Shih et al. New Biotechnology
- Growth Factors Cross-Linked to Collagen Microcarriers Promote Expansion and Chondrogenic Differentiation of Human Mesenchymal Stem Cells
- (2015) Alessandro Bertolo et al. TISSUE ENGINEERING PART A
- Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs
- (2015) Donald G. Phinney et al. Nature Communications
- Optimization of human mesenchymal stem cell manufacturing: the effects of animal/xeno-free media
- (2015) Angelos Oikonomopoulos et al. Scientific Reports
- Comparative analysis of human mesenchymal stem cells from bone marrow and adipose tissue under xeno-free conditions for cell therapy
- (2015) Chun-yu Li et al. Stem Cell Research & Therapy
- Concise Review: Process Development Considerations for Cell Therapy
- (2015) Andrew Campbell et al. Stem Cells Translational Medicine
- Biodegradable Gelatin Microcarriers Facilitate Re-Epithelialization of Human Cutaneous Wounds - An In Vitro Study in Human Skin
- (2015) Susanna Lönnqvist et al. PLoS One
- IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival
- (2015) Serena Lunardi et al. Oncotarget
- Mitochondrial Transfer of Induced Pluripotent Stem Cell–Derived Mesenchymal Stem Cells to Airway Epithelial Cells Attenuates Cigarette Smoke–Induced Damage
- (2014) Xiang Li et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors
- (2014) Rasheena Edmondson et al. ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
- A xenogeneic-free bioreactor system for the clinical-scale expansion of human mesenchymal stem/stromal cells
- (2014) Francisco dos Santos et al. BIOTECHNOLOGY AND BIOENGINEERING
- Growth and functional harvesting of human mesenchymal stromal cells cultured on a microcarrier-based system
- (2014) Sâmia R. Caruso et al. BIOTECHNOLOGY PROGRESS
- IL-8 enhances the angiogenic potential of human bone marrow mesenchymal stem cells by increasing vascular endothelial growth factor
- (2014) Yun Hou et al. CELL BIOLOGY INTERNATIONAL
- MSC-Based Product Characterization for Clinical Trials: An FDA Perspective
- (2014) Michael Mendicino et al. Cell Stem Cell
- On the fluid dynamics of a laboratory scale single-use stirred bioreactor
- (2014) A.O.O. Odeleye et al. CHEMICAL ENGINEERING SCIENCE
- Stem cell bioprocess engineering towards cGMP production and clinical applications
- (2014) Sébastien Sart et al. CYTOTECHNOLOGY
- Integrin expression in stem cells from bone marrow and adipose tissue during chondrogenic differentiation
- (2014) Ulrich Goessler et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- IDO-Independent Suppression of T Cell Effector Function by IFN- -Licensed Human Mesenchymal Stromal Cells
- (2014) R. Chinnadurai et al. JOURNAL OF IMMUNOLOGY
- Donor age negatively impacts adipose tissue-derived mesenchymal stem cell expansion and differentiation
- (2014) Mahmood S Choudhery et al. Journal of Translational Medicine
- Advances in cell culture: anchorage dependence
- (2014) O.-W. Merten PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Production of Human Pluripotent Stem Cell Therapeutics under Defined Xeno-free Conditions: Progress and Challenges
- (2014) Yongjia Fan et al. Stem Cell Reviews and Reports
- Do Cryopreserved Mesenchymal Stromal Cells Display Impaired Immunomodulatory and Therapeutic Properties?
- (2014) Guido Moll et al. STEM CELLS
- Donor age negatively affects the immunoregulatory properties of both adipose and bone marrow derived mesenchymal stem cells
- (2014) Lehao W. Wu et al. TRANSPLANT IMMUNOLOGY
- Treatment of Graft versus Host Disease with Mesenchymal Stromal Cells: A Phase I Study on 40 Adult and Pediatric Patients
- (2013) Martino Introna et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Application of human mesenchymal and pluripotent stem cell microcarrier cultures in cellular therapy: Achievements and future direction
- (2013) Allen Kuan-Liang Chen et al. BIOTECHNOLOGY ADVANCES
- Culture of human mesenchymal stem cells on microcarriers in a 5 l stirred-tank bioreactor
- (2013) Qasim A. Rafiq et al. BIOTECHNOLOGY LETTERS
- Phenotype, donor age and gender affect function of human bone marrow-derived mesenchymal stromal cells
- (2013) Georg Siegel et al. BMC Medicine
- Serum-free media for the production of human mesenchymal stromal cells: a review
- (2013) S. Gottipamula et al. CELL PROLIFERATION
- Interaction between Adipose Tissue-Derived Mesenchymal Stem Cells and Regulatory T-Cells
- (2013) Anja U. Engela et al. CELL TRANSPLANTATION
- Distinct Immunomodulatory and Migratory Mechanisms Underpin the Therapeutic Potential of Human Mesenchymal Stem Cells in Autoimmune Demyelination
- (2013) Natalie L. Payne et al. CELL TRANSPLANTATION
- The mesenchymal stromal cells dilemma—does a negative phase III trial of random donor mesenchymal stromal cells in steroid-resistant graft-versus-host disease represent a death knell or a bump in the road?
- (2013) Jacques Galipeau CYTOTHERAPY
- Multipotent stromal cells skew monocytes towards an anti-inflammatory interleukin-10-producing phenotype by production of interleukin-6
- (2013) S. M. Melief et al. HAEMATOLOGICA
- Prostaglandin E2 Potentiates Mesenchymal Stem Cell-Induced IL-10+IFN- +CD4+ Regulatory T Cells To Control Transplant Arteriosclerosis
- (2013) W.-T. Hsu et al. JOURNAL OF IMMUNOLOGY
- Alveolar Macrophages Are Critical for the Inhibition of Allergic Asthma by Mesenchymal Stromal Cells
- (2013) L. J. Mathias et al. JOURNAL OF IMMUNOLOGY
- Large-scale expansion of pre-isolated bone marrow mesenchymal stromal cells in serum-free conditions
- (2013) Sanjay Gottipamula et al. Journal of Tissue Engineering and Regenerative Medicine
- Synthetic Surface for Expansion of Human Mesenchymal Stem Cells in Xeno-Free, Chemically Defined Culture Conditions
- (2013) Paula J. Dolley-Sonneville et al. PLoS One
- Macrophages are involved in the protective role of human umbilical cord-derived stromal cells in renal ischemia–reperfusion injury
- (2013) Wei Li et al. Stem Cell Research
- Clinical-Grade Mesenchymal Stromal Cells Produced Under Various Good Manufacturing Practice Processes Differ in Their Immunomodulatory Properties: Standardization of Immune Quality Controls
- (2013) Cedric Menard et al. STEM CELLS AND DEVELOPMENT
- Decidual Stromal Cells Promote Regulatory T Cells and Suppress Alloreactivity in a Cell Contact-Dependent Manner
- (2013) Tom Erkers et al. STEM CELLS AND DEVELOPMENT
- Human-Derived Alternatives to Fetal Bovine Serum in Cell Culture
- (2013) Karin Witzeneder et al. TRANSFUSION MEDICINE AND HEMOTHERAPY
- Development of fully defined xeno-free culture system for the preparation and propagation of cell therapy-compliant human adipose stem cells
- (2013) Mimmi Patrikoski et al. Stem Cell Research & Therapy
- Adipose Tissue-Derived Multipotent Stromal Cells Have a Higher Immunomodulatory Capacity Than Their Bone Marrow-Derived Counterparts
- (2013) Sara M. Melief et al. Stem Cells Translational Medicine
- MSCs: Delivery Routes and Engraftment, Cell-Targeting Strategies, and Immune Modulation
- (2013) Thomas J. Kean et al. Stem Cells International
- Multifarious roles of sialic acids in immunity
- (2012) Ajit Varki et al. Annals of the New York Academy of Sciences
- Large-scale production of human mesenchymal stem cells for clinical applications
- (2012) Sunghoon Jung et al. BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
- Human platelet lysate is an alternative to fetal bovine serum for large-scale expansion of bone marrow-derived mesenchymal stromal cells
- (2012) Sanjay Gottipamula et al. BIOTECHNOLOGY LETTERS
- Limiting cell aggregation during mesenchymal stem cell expansion on microcarriers
- (2012) Caroline Ferrari et al. BIOTECHNOLOGY PROGRESS
- Mesenchymal-Stem-Cell-Induced Immunoregulation Involves FAS-Ligand-/FAS-Mediated T Cell Apoptosis
- (2012) Kentaro Akiyama et al. Cell Stem Cell
- Platelet lysate from whole blood-derived pooled platelet concentrates and apheresis-derived platelet concentrates for the isolation and expansion of human bone marrow mesenchymal stromal cells: production process, content and identification of active components
- (2012) Natalie Fekete et al. CYTOTHERAPY
- Microcarrier-based Expansion Process for hMSCs with High Vitality and Undifferentiated Characteristics
- (2012) Christiane L. Elseberg et al. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
- Lateral spacing of adhesion peptides influences human mesenchymal stem cell behaviour
- (2012) J. E. Frith et al. JOURNAL OF CELL SCIENCE
- Modulation of mesenchymal stem cell actin organization on conventional microcarriers for proliferation and differentiation in stirred bioreactors
- (2012) Sébastien Sart et al. Journal of Tissue Engineering and Regenerative Medicine
- Redifferentiation of dedifferentiated human articular chondrocytes: comparison of 2D and 3D cultures
- (2012) M.M.J. Caron et al. OSTEOARTHRITIS AND CARTILAGE
- Mesenchymal Stem Cells Secrete Multiple Cytokines That Promote Angiogenesis and Have Contrasting Effects on Chemotaxis and Apoptosis
- (2012) Robert A. Boomsma et al. PLoS One
- A Synthetic, Xeno-Free Peptide Surface for Expansion and Directed Differentiation of Human Induced Pluripotent Stem Cells
- (2012) Sha Jin et al. PLoS One
- Concise Review: The Evolution of human pluripotent stem cell culture: From feeder cells to synthetic coatings
- (2012) L.G. Villa-Diaz et al. STEM CELLS
- Mesenchymal Stromal Cells Improve Survival During Sepsis in the Absence of Heme Oxygenase-1: The Importance of Neutrophils
- (2012) Sean R. R. Hall et al. STEM CELLS
- Tailored Integrin–Extracellular Matrix Interactions to Direct Human Mesenchymal Stem Cell Differentiation
- (2012) Jessica Ellen Frith et al. STEM CELLS AND DEVELOPMENT
- Same or Not the Same? Comparison of Adipose Tissue-Derived Versus Bone Marrow-Derived Mesenchymal Stem and Stromal Cells
- (2012) Marius Strioga et al. STEM CELLS AND DEVELOPMENT
- A review of protein adsorption on bioceramics
- (2012) K. Wang et al. Interface Focus
- Safety and Complications Reporting Update on the Re-Implantation of Culture-Expanded Mesenchymal Stem Cells Using Autologous Platelet Lysate Technique
- (2012) Christopher J. Centeno et al. Current Stem Cell Research & Therapy
- Mesenchymal stem cells are short-lived and do not migrate beyond the lungs after intravenous infusion
- (2012) E. Eggenhofer et al. Frontiers in Immunology
- Long-Term Complications, Immunologic Effects, and Role of Passage for Outcome in Mesenchymal Stromal Cell Therapy
- (2011) Lena von Bahr et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- A modular approach to the engineering of a centimeter-sized bone tissue construct with human amniotic mesenchymal stem cells-laden microcarriers
- (2011) Maiqin Chen et al. BIOMATERIALS
- Spontaneous osteogenesis of MSCs cultured on 3D microcarriers through alteration of cytoskeletal tension
- (2011) Pei-Chi Tseng et al. BIOMATERIALS
- Expansion of human mesenchymal stem cells on microcarriers
- (2011) Christopher J. Hewitt et al. BIOTECHNOLOGY LETTERS
- Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF- B signaling in resident macrophages
- (2011) H. Choi et al. BLOOD
- Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC
- (2011) Ralf Hass et al. Cell Communication and Signaling
- Human Mesenchymal Stem Cells Are Susceptible to Lysis by CD8+ T Cells and NK Cells
- (2011) Meindert J. Crop et al. CELL TRANSPLANTATION
- Mesenchymal stem cells expanded in human platelet lysate display a decreased inhibitory capacity on T- and NK-cell proliferation and function
- (2011) Heba Abdelrazik et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Mesenchymal stem cell inhibition of T-helper 17 cell- differentiation is triggered by cell-cell contact and mediated by prostaglandin E2 via the EP4 receptor
- (2011) Michelle M. Duffy et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Mesenchymal stromal cell ‘licensing’: a multistep process
- (2011) M Krampera LEUKEMIA
- Human MSC Suppression Correlates With Cytokine Induction of Indoleamine 2,3-Dioxygenase and Bystander M2 Macrophage Differentiation
- (2011) Moïra François et al. MOLECULAR THERAPY
- A bioinformatic assay for pluripotency in human cells
- (2011) Franz-Josef Müller et al. NATURE METHODS
- Interferon-γ Regulates the Proliferation and Differentiation of Mesenchymal Stem Cells via Activation of Indoleamine 2,3 Dioxygenase (IDO)
- (2011) Juliana Croitoru-Lamoury et al. PLoS One
- The Cell Surface Proteome of Human Mesenchymal Stromal Cells
- (2011) Christian Niehage et al. PLoS One
- Toll-Like Receptor-3-Activated Human Mesenchymal Stromal Cells Significantly Prolong the Survival and Function of Neutrophils
- (2011) Marco A. Cassatella et al. STEM CELLS
- Expansion and Delivery of Adipose-Derived Mesenchymal Stem Cells on Three Microcarriers for Soft Tissue Regeneration
- (2011) Yalei Zhou et al. TISSUE ENGINEERING PART A
- Design and Characterization of Tissue-Specific Extracellular Matrix-Derived Microcarriers
- (2011) Allison E.B. Turner et al. TISSUE ENGINEERING PART C-METHODS
- “Humanized” Stem Cell Culture Techniques: The Animal Serum Controversy
- (2011) Chandana Tekkatte et al. Stem Cells International
- Allogeneic mesenchymal stem cells prevent allergic airway inflammation by inducing murine regulatory T cells
- (2010) H. Kavanagh et al. ALLERGY
- Suspension Culture of Mammalian Cells Using Thermosensitive Microcarrier that Allows Cell Detachment without Proteolytic Enzyme Treatment
- (2010) Hee Seok Yang et al. CELL TRANSPLANTATION
- Mesenchymal stromal cells use PGE2 to modulate activation and proliferation of lymphocyte subsets: Combined comparison of adipose tissue, Wharton’s Jelly and bone marrow sources
- (2010) Mehdi Najar et al. CELLULAR IMMUNOLOGY
- Animal serum-free expansion and differentiation of human mesenchymal stromal cells
- (2010) Tino Felka et al. CYTOTHERAPY
- Fetal and adult multipotent mesenchymal stromal cells are killed by different pathways
- (2010) Cecilia Götherström et al. CYTOTHERAPY
- An Improved Harvest andin VitroExpansion Protocol for Murine Bone Marrow-Derived Mesenchymal Stem Cells
- (2010) Song Xu et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Maximizing the ex vivo expansion of human mesenchymal stem cells using a microcarrier-based stirred culture system
- (2010) Gemma Eibes et al. JOURNAL OF BIOTECHNOLOGY
- Inflammatory Cytokine-Induced Intercellular Adhesion Molecule-1 and Vascular Cell Adhesion Molecule-1 in Mesenchymal Stem Cells Are Critical for Immunosuppression
- (2010) Guangwen Ren et al. JOURNAL OF IMMUNOLOGY
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- (2010) S. Ghannam et al. JOURNAL OF IMMUNOLOGY
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- (2010) Fanjun Cheng Molecular Medicine Reports
- Synthetic peptide-acrylate surfaces for long-term self-renewal and cardiomyocyte differentiation of human embryonic stem cells
- (2010) Zara Melkoumian et al. NATURE BIOTECHNOLOGY
- Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
- (2010) Subhra K Biswas et al. NATURE IMMUNOLOGY
- A New Mesenchymal Stem Cell (MSC) Paradigm: Polarization into a Pro-Inflammatory MSC1 or an Immunosuppressive MSC2 Phenotype
- (2010) Ruth S. Waterman et al. PLoS One
- Human Gingiva-Derived Mesenchymal Stem Cells Elicit Polarization of M2 Macrophages and Enhance Cutaneous Wound Healing
- (2010) Qun-Zhou Zhang et al. STEM CELLS
- Interferon-γ and Tumor Necrosis Factor-α Differentially Affect Cytokine Expression and Migration Properties of Mesenchymal Stem Cells
- (2010) Hatim Hemeda et al. STEM CELLS AND DEVELOPMENT
- Adult human mesenchymal cells proliferate and migrate in response to chemokines expressed in demyelination
- (2010) Claire M. Rice et al. Cell Adhesion & Migration
- Expansion and delivery of human fibroblasts on micronized acellular dermal matrix for skin regeneration
- (2009) Xiaojun Zhang et al. BIOMATERIALS
- MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: central role of MSC-derived prostaglandin E2
- (2009) G. M. Spaggiari et al. BLOOD
- Functional Alteration of the Lymphoma Stromal Cell Niche by the Cytokine Context: Role of Indoleamine-2,3 Dioxygenase
- (2009) H. Maby-El Hajjami et al. CANCER RESEARCH
- Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6
- (2009) Ryang Hwa Lee et al. Cell Stem Cell
- Cell contact, prostaglandin E2and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25Highforkhead box P3+regulatory T cells
- (2009) K. English et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Soluble mediators from mesenchymal stem cells suppress T cell proliferation by inducing IL-10
- (2009) Seung-Ha Yang et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Mesenchymal stem cells suppress B-cell terminal differentiation
- (2009) Sadaki Asari et al. EXPERIMENTAL HEMATOLOGY
- Characterization of integrin engagement during defined human embryonic stem cell culture
- (2009) Ying Meng et al. FASEB JOURNAL
- Interleukin-6 maintains bone marrow-derived mesenchymal stem cell stemness by an ERK1/2-dependent mechanism
- (2009) Katie L. Pricola et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
- (2009) Loise M. Francisco et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Administration of bone marrow stromal cells ameliorates experimental autoimmune myasthenia gravis by altering the balance of Th1/Th2/Th17/Treg cell subsets through the secretion of TGF-β
- (2009) Qing-fei Kong et al. JOURNAL OF NEUROIMMUNOLOGY
- Direct Evidence of Mesenchymal Stem Cell Tropism for Tumor and Wounding Microenvironments Using In Vivo Bioluminescent Imaging
- (2009) Shannon Kidd et al. STEM CELLS
- Direct Imaging of Immune Rejection and Memory Induction by Allogeneic Mesenchymal Stromal Cells
- (2009) Lior Zangi et al. STEM CELLS
- Human Alternatives to Fetal Bovine Serum for the Expansion of Mesenchymal Stromal Cells from Bone Marrow
- (2009) Karen Bieback et al. STEM CELLS
- Dynamic Three-Dimensional Culture Methods Enhance Mesenchymal Stem Cell Properties and Increase Therapeutic Potential
- (2009) Jessica E. Frith et al. TISSUE ENGINEERING PART C-METHODS
- Treatment of refractory acute GVHD with third-party MSC expanded in platelet lysate-containing medium
- (2008) M von Bonin et al. BONE MARROW TRANSPLANTATION
- Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide
- (2008) Guangwen Ren et al. Cell Stem Cell
- IFN-γ activation of mesenchymal stem cells for treatment and prevention of graft versus host disease
- (2008) David Polchert et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Effects of plating density and culture time on bone marrow stromal cell characteristics
- (2008) Birgit Neuhuber et al. EXPERIMENTAL HEMATOLOGY
- Culturing of Human Mesenchymal Stem Cells as Three-dimensional Aggregates Induces Functional Expression of CXCR4 That Regulates Adhesion to Endothelial Cells
- (2008) Irina A. Potapova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ear mesenchymal stem cells: An efficient adult multipotent cell population fit for rapid and scalable expansion
- (2008) Sébastien Sart et al. JOURNAL OF BIOTECHNOLOGY
- Expansion of mesenchymal stem cells using a microcarrier-based cultivation system: growth and metabolism
- (2008) D. Schop et al. Journal of Tissue Engineering and Regenerative Medicine
- Mesenchymal Stromal Cells Engineered to Express Erythropoietin Induce Anti-erythropoietin Antibodies and Anemia in Allorecipients
- (2008) Philippe M Campeau et al. MOLECULAR THERAPY
- Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production
- (2008) Krisztián Németh et al. NATURE MEDICINE
- Pulmonary Passage is a Major Obstacle for Intravenous Stem Cell Delivery: The Pulmonary First-Pass Effect
- (2008) Uwe M. Fischer et al. STEM CELLS AND DEVELOPMENT
- Constitutive neutrophil apoptosis: Mechanisms and regulation
- (2007) Hongbo R. Luo et al. AMERICAN JOURNAL OF HEMATOLOGY
- Toll-Like Receptors on Human Mesenchymal Stem Cells Drive Their Migration and Immunomodulating Responses
- (2007) Suzanne L. Tomchuck et al. STEM CELLS
- Bone Marrow-Derived Mesenchymal Stem Cells Induce Both Polyclonal Expansion and Differentiation of B Cells Isolated from Healthy Donors and Systemic Lupus Erythematosus Patients
- (2007) Elisabetta Traggiai et al. STEM CELLS
- Human Leukocyte Antigen-G5 Secretion by Human Mesenchymal Stem Cells Is Required to Suppress T Lymphocyte and Natural Killer Function and to Induce CD4+CD25highFOXP3+Regulatory T Cells
- (2007) Zohair Selmani et al. STEM CELLS
- Human Mesenchymal Stem Cells Inhibit Neutrophil Apoptosis: A Model for Neutrophil Preservation in the Bone Marrow Niche
- (2007) Lizzia Raffaghello et al. STEM CELLS
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