Cryopreserved Mesenchymal Stromal Cells Are Susceptible to T-Cell Mediated Apoptosis Which Is Partly Rescued by IFNγ Licensing

Cryopreservation of cells: FT-IR monitoring of lipid membrane at freeze–thaw cycles

(2016) A. Giugliarelli et al.   BIOPHYSICAL CHEMISTRY

Co-transplantation of multipotent mesenchymal stromal cells in allogeneic hematopoietic stem cell transplantation: A systematic review and meta-analysis

(2016) Merete Kallekleiv et al.   CYTOTHERAPY

International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials

(2016) Jacques Galipeau et al.   CYTOTHERAPY

Mesenchymal stromal cells derived from various tissues: Biological, clinical and cryopreservation aspects

(2015) Leah A. Marquez-Curtis et al.   CRYOBIOLOGY

Investigating membrane and mitochondrial cryobiological responses of HUVEC using interrupted cooling protocols

(2015) Anthony J.F. Reardon et al.   CRYOBIOLOGY

The challenge of defining mesenchymal stromal cell potency assays and their potential use as release criteria

(2015) Jacques Galipeau et al.   CYTOTHERAPY

Clinical mesenchymal stromal cell products undergo functional changes in response to freezing

(2015) Kathryn Pollock et al.   CYTOTHERAPY

Cryopreservation does not alter main characteristics of Good Manufacturing Process–grade human multipotent mesenchymal stromal cells including immunomodulating potential and lack of malignant transformation

(2015) Jana Luetzkendorf et al.   CYTOTHERAPY

Efficacy of immunotherapy with mesenchymal stem cells in man: a systematic review

(2015) Franka Luk et al.   Expert Review of Clinical Immunology

Mesenchymal Stromal Cells Derived From Crohn's Patients Deploy Indoleamine 2,3-dioxygenase-mediated Immune Suppression, Independent of Autophagy

(2015) Raghavan Chinnadurai et al.   MOLECULAR THERAPY

Mesenchymal stem/stromal cells precondition lung monocytes/macrophages to produce tolerance against allo- and autoimmunity in the eye

(2015) Jung Hwa Ko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryopreservation alters the membrane and cytoskeletal protein profile of platelet microparticles

(2015) Sarah Raynel et al.   TRANSFUSION

Freshly Thawed and Continuously Cultured Human Bone Marrow-Derived Mesenchymal Stromal Cells Comparably Ameliorate Allergic Airways Inflammation in Immunocompetent Mice

(2015) Fernanda F. Cruz et al.   Stem Cells Translational Medicine

Role of the Apoptosis Pathway in Cryopreservation-Induced Cell Death in Mesenchymal Stem Cells Derived from Umbilical Cord Blood

(2014) Akalabya Bissoyi et al.   BIOPRESERVATION AND BIOBANKING

IDO-Independent Suppression of T Cell Effector Function by IFN- -Licensed Human Mesenchymal Stromal Cells

(2014) R. Chinnadurai et al.   JOURNAL OF IMMUNOLOGY

Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implications

(2014) Ying Wang et al.   NATURE IMMUNOLOGY

Do ABO Blood Group Antigens Hamper the Therapeutic Efficacy of Mesenchymal Stromal Cells?

(2014) Guido Moll et al.   PLoS One

Do Cryopreserved Mesenchymal Stromal Cells Display Impaired Immunomodulatory and Therapeutic Properties?

(2014) Guido Moll et al.   STEM CELLS

Mesenchymal Stem Cells for Regenerative Therapy: Optimization of Cell Preparation Protocols

(2014) Chiho Ikebe et al.   Biomed Research International

Actin Cytoskeletal Disruption following Cryopreservation Alters the Biodistribution of Human Mesenchymal Stromal Cells In Vivo

(2014) Raghavan Chinnadurai et al.   Stem Cell Reports

The effect of platelet lysate fibrinogen on the functionality of MSCs in immunotherapy

(2013) Ian B. Copland et al.   BIOMATERIALS

Sublethal heat shock induces premature senescence rather than apoptosis in human mesenchymal stem cells

(2013) Larisa L. Alekseenko et al.   CELL STRESS & CHAPERONES

A Phase 2 Study of Allogeneic Mesenchymal Stromal Cells for Luminal Crohn's Disease Refractory to Biologic Therapy

(2013) Geoffrey M. Forbes et al.   Clinical Gastroenterology and Hepatology

Cryopreservation of alginate encapsulated mesenchymal stromal cells

(2013) Alexey I. Pravdyuk et al.   CRYOBIOLOGY

Mechanisms of Immune Modulation by Mesenchymal Stromal Cells and Clinical Translation

(2013) J. Stagg et al.   CURRENT MOLECULAR MEDICINE

Human platelet lysate stimulates high-passage and senescent human multipotent mesenchymal stromal cell growth and rejuvenation in vitro

(2013) Sarah Griffiths et al.   CYTOTHERAPY

The mesenchymal stromal cells dilemma—does a negative phase III trial of random donor mesenchymal stromal cells in steroid-resistant graft-versus-host disease represent a death knell or a bump in the road?

(2013) Jacques Galipeau   CYTOTHERAPY

Unexpected low-dose toxicity of the universal solvent DMSO

(2013) Joana Galvao et al.   FASEB JOURNAL

Alveolar Macrophages Are Critical for the Inhibition of Allergic Asthma by Mesenchymal Stromal Cells

(2013) L. J. Mathias et al.   JOURNAL OF IMMUNOLOGY

Pre-conditioned mesenchymal stem cells: a better way for cell-based therapy

(2013) Qing Li et al.   Stem Cell Research & Therapy

Mesenchymal-Stem-Cell-Induced Immunoregulation Involves FAS-Ligand-/FAS-Mediated T Cell Apoptosis

(2012) Kentaro Akiyama et al.   Cell Stem Cell

Magnetic Cryopreservation for Dental Pulp Stem Cells

(2012) Sheng-Yang Lee et al.   CELLS TISSUES ORGANS

New insights on translational development of mesenchymal stromal cells for suppressor therapy

(2012) Moïra François et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Intraperitoneal but Not Intravenous Cryopreserved Mesenchymal Stromal Cells Home to the Inflamed Colon and Ameliorate Experimental Colitis

(2012) Morgana T. L. Castelo-Branco et al.   PLoS One

Safety of Cell Therapy with Mesenchymal Stromal Cells (SafeCell): A Systematic Review and Meta-Analysis of Clinical Trials

(2012) Manoj M. Lalu et al.   PLoS One

Analysis of Tissues Following Mesenchymal Stromal Cell Therapy in Humans Indicates Limited Long-Term Engraftment and No Ectopic Tissue Formation

(2012) L. von Bahr et al.   STEM CELLS

Cryopreserved mesenchymal stromal cells display impaired immunosuppressive properties as a result of heat-shock response and impaired interferon-γ licensing

(2011) Moïra François et al.   CYTOTHERAPY

Pretreatment with Interferon-γ Enhances the Therapeutic Activity of Mesenchymal Stromal Cells in Animal Models of Colitis

(2011) Marjolijn Duijvestein et al.   STEM CELLS

Adhesion molecules

(2011) Guangwen Ren et al.   Cell Adhesion & Migration

Inflammatory Cytokine-Induced Intercellular Adhesion Molecule-1 and Vascular Cell Adhesion Molecule-1 in Mesenchymal Stem Cells Are Critical for Immunosuppression

(2010) Guangwen Ren et al.   JOURNAL OF IMMUNOLOGY

Polyampholytes as low toxic efficient cryoprotective agents with antifreeze protein properties

(2009) Kazuaki Matsumura et al.   BIOMATERIALS

Cell contact, prostaglandin E2and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25Highforkhead box P3+regulatory T cells

(2009) K. English et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Allogeneic Mesenchymal Stem Cells for Treatment of Experimental Autoimmune Encephalomyelitis

(2009) Moutih Rafei et al.   MOLECULAR THERAPY

In vivo trafficking and survival of cytokine-induced killer cells resulting in minimal GVHD with retention of antitumor activity

(2008) R. Nishimura et al.   BLOOD

IFN-γ activation of mesenchymal stem cells for treatment and prevention of graft versus host disease

(2008) David Polchert et al.   EUROPEAN JOURNAL OF IMMUNOLOGY