Immunomodulation By Therapeutic Mesenchymal Stromal Cells (MSC) Is Triggered Through Phagocytosis of MSC By Monocytic Cells

Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation

(2017) Antonio Galleu et al.   Science Translational Medicine

Cytokine treatment optimises the immunotherapeutic effects of umbilical cord-derived MSC for treatment of inflammatory liver disease

(2017) Samantha F. H. de Witte et al.   Stem Cell Research & Therapy

Mesenchymal Stromal Cells Modulate Monocytes Trafficking in Coxsackievirus B3-Induced Myocarditis

(2017) Kapka Miteva et al.   Stem Cells Translational Medicine

Membrane particles generated from mesenchymal stromal cells modulate immune responses by selective targeting of pro-inflammatory monocytes

(2017) Fabiany da C. Gonçalves et al.   Scientific Reports

Human macrophages induce CD4+ Foxp3+ regulatory T cells via binding and re-release of TGF-β

(2016) Angelika Schmidt et al.   IMMUNOLOGY AND CELL BIOLOGY

Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind controlled trial

(2016) Julián Panés et al.   LANCET

Mesenchymal Stem Cells Induce Suppressive Macrophages Through Phagocytosis in a Mouse Model of Asthma

(2016) Faouzi Braza et al.   STEM CELLS

Umbilical Cord-derived Mesenchymal Stem Cells Instruct Monocytes Towards an IL10-producing Phenotype by Secreting IL6 and HGF

(2016) Yinan Deng et al.   Scientific Reports

The Human Fetal Placenta Promotes Tolerance against the Semiallogeneic Fetus by Inducing Regulatory T Cells and Homeostatic M2 Macrophages

(2015) Judit Svensson-Arvelund et al.   JOURNAL OF IMMUNOLOGY

Mesenchymal stem/stromal cells precondition lung monocytes/macrophages to produce tolerance against allo- and autoimmunity in the eye

(2015) Jung Hwa Ko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allogeneic mesenchymal stem cell transplantation for lupus nephritis patients refractory to conventional therapy

(2014) Fei Gu et al.   CLINICAL RHEUMATOLOGY

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Randomized trial of autologous bone marrow mesenchymal stem cells transplantation for hepatitis B virus cirrhosis: Regulation of Treg/Th17 cells

(2014) Lanman Xu et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Pretransplant Infusion of Mesenchymal Stem Cells Prolongs the Survival of a Semiallogeneic Heart Transplant through the Generation of Regulatory T Cells

(2014) F. Casiraghi et al.   JOURNAL OF IMMUNOLOGY

Induction of immunomodulatory monocytes by human mesenchymal stem cell-derived hepatocyte growth factor through ERK1/2

(2014) P.-M. Chen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Life and Fate of Mesenchymal Stem Cells

(2014) Elke Eggenhofer et al.   Frontiers in Immunology

A Phase 2 Study of Allogeneic Mesenchymal Stromal Cells for Luminal Crohn's Disease Refractory to Biologic Therapy

(2013) Geoffrey M. Forbes et al.   Clinical Gastroenterology and Hepatology

Efficacy and safety of mesenchymal stromal cell treatment from related donors for patients with refractory aplastic anemia

(2013) Yang Xiao et al.   CYTOTHERAPY

Multipotent stromal cells skew monocytes towards an anti-inflammatory interleukin-10-producing phenotype by production of interleukin-6

(2013) S. M. Melief et al.   HAEMATOLOGICA

Alterations in the Cellular Immune Compartment of Patients Treated with Third-Party Mesenchymal Stromal Cells Following Allogeneic Hematopoietic Stem Cell Transplantation

(2013) Regina Jitschin et al.   STEM CELLS

Multipotent stromal cells induce human regulatory T cells through a novel pathway involving skewing of monocytes toward anti-inflammatory macrophages

(2013) Sara M. Melief et al.   STEM CELLS

Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Fourth Meeting

(2013) Marcella Franquesa et al.   TRANSPLANTATION

Allogeneic mesenchymal stem cell treatment alleviates experimental and clinical Sjogren syndrome

(2012) J. Xu et al.   BLOOD

Human mesenchymal stem cells suppress donor CD4+T cell proliferation and reduce pathology in a humanized mouse model of acute graft-versus-host disease

(2012) L. M. Tobin et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Long term effects of the implantation of Wharton^|^rsquo;s jelly-derived mesenchymal stem cells from the umbilical cord for newly-onset type 1 diabetes mellitus

(2012) Jianxia Hu et al.   ENDOCRINE JOURNAL

Exposure to supernatants of macrophages that phagocytized dead mesenchymal stem cells improves hypoxic cardiomyocytes survival

(2012) Wenbin Lu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Induction Therapy With Autologous Mesenchymal Stem Cells in Living-Related Kidney Transplants

(2012) Jianming Tan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Human umbilical cord mesenchymal stem cells improve liver function and ascites in decompensated liver cirrhosis patients

(2012) Zheng Zhang et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Efficient Clearance of Early Apoptotic Cells by Human Macrophages Requires M2c Polarization and MerTK Induction

(2012) G. Zizzo et al.   JOURNAL OF IMMUNOLOGY

Mesenchymal stem cells are short-lived and do not migrate beyond the lungs after intravenous infusion

(2012) E. Eggenhofer et al.   Frontiers in Immunology

Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's disease

(2011) R. Ciccocioppo et al.   GUT

Allogeneic mesenchymal stem cells prevent allergic airway inflammation by inducing murine regulatory T cells

(2010) H. Kavanagh et al.   ALLERGY

Allogenic mesenchymal stem cells transplantation in refractory systemic lupus erythematosus: a pilot clinical study

(2010) J. Liang et al.   ANNALS OF THE RHEUMATIC DISEASES

Co-infusion of ex vivo-expanded, parental MSCs prevents life-threatening acute GVHD, but does not reduce the risk of graft failure in pediatric patients undergoing allogeneic umbilical cord blood transplantation

(2010) M E Bernardo et al.   BONE MARROW TRANSPLANTATION

Umbilical Cord-Derived Mesenchymal Stromal Cells Modulate Monocyte Function to Suppress T Cell Proliferation

(2010) A. J. Cutler et al.   JOURNAL OF IMMUNOLOGY

Mouse Bone Marrow-Derived Mesenchymal Stromal Cells Turn Activated Macrophages into a Regulatory-Like Profile

(2010) Julian Maggini et al.   PLoS One

Mesenchymal stem cell–educated macrophages: A novel type of alternatively activated macrophages

(2009) Jaehyup Kim et al.   EXPERIMENTAL HEMATOLOGY

Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis

(2009) E Gonzalez-Rey et al.   GUT

Adipose-Derived Mesenchymal Stem Cells Ameliorate Chronic Experimental Autoimmune Encephalomyelitis

(2009) Gabriela Constantin et al.   STEM CELLS

Adipose-Derived Mesenchymal Stem Cells Alleviate Experimental Colitis by Inhibiting Inflammatory and Autoimmune Responses

(2008) Manuel A. González et al.   GASTROENTEROLOGY

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

(2008) Katarina Le Blanc et al.   LANCET

Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

(2008) Krisztián Németh et al.   NATURE MEDICINE

Pulmonary Passage is a Major Obstacle for Intravenous Stem Cell Delivery: The Pulmonary First-Pass Effect

(2008) Uwe M. Fischer et al.   STEM CELLS AND DEVELOPMENT

Mesenchymal stem cells can induce long-term acceptance of solid organ allografts in synergy with low-dose mycophenolate

(2008) F.C. Popp et al.   TRANSPLANT IMMUNOLOGY