Clinical-Grade Mesenchymal Stromal Cells Produced Under Various Good Manufacturing Practice Processes Differ in Their Immunomodulatory Properties: Standardization of Immune Quality Controls

Platelet lysate from whole blood-derived pooled platelet concentrates and apheresis-derived platelet concentrates for the isolation and expansion of human bone marrow mesenchymal stromal cells: production process, content and identification of active components

(2012) Natalie Fekete et al.   CYTOTHERAPY

Characterization and functionality of the CD200–CD200R system during mesenchymal stromal cell interactions with T-lymphocytes

(2012) Mehdi Najar et al.   IMMUNOLOGY LETTERS

Induction Therapy With Autologous Mesenchymal Stem Cells in Living-Related Kidney Transplants

(2012) Jianming Tan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study

(2012) Peter Connick et al.   LANCET NEUROLOGY

GMP-Compliant Isolation and Large-Scale Expansion of Bone Marrow-Derived MSC

(2012) Natalie Fekete et al.   PLoS One

Analysis of Tissues Following Mesenchymal Stromal Cell Therapy in Humans Indicates Limited Long-Term Engraftment and No Ectopic Tissue Formation

(2012) L. von Bahr et al.   STEM CELLS

Same or Not the Same? Comparison of Adipose Tissue-Derived Versus Bone Marrow-Derived Mesenchymal Stem and Stromal Cells

(2012) Marius Strioga et al.   STEM CELLS AND DEVELOPMENT

Tryptophan catabolism is associated with acute GVHD after human allogeneic stem cell transplantation and indicates activation of indoleamine 2,3-dioxygenase

(2011) K. Landfried et al.   BLOOD

DNAM-1 ligand expression on Ag-stimulated T lymphocytes is mediated by ROS-dependent activation of DNA-damage response: relevance for NK-T cell interaction

(2011) M. Ardolino et al.   BLOOD

Cryopreserved mesenchymal stromal cells display impaired immunosuppressive properties as a result of heat-shock response and impaired interferon-γ licensing

(2011) Moïra François et al.   CYTOTHERAPY

Mesenchymal stem cells expanded in human platelet lysate display a decreased inhibitory capacity on T- and NK-cell proliferation and function

(2011) Heba Abdelrazik et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's disease

(2011) R. Ciccocioppo et al.   GUT

Fibroblast growth factor-2 enhances NK sensitivity of hepatocellular carcinoma cells

(2011) Hinako Tsunematsu et al.   INTERNATIONAL JOURNAL OF CANCER

Mesenchymal stromal cell ‘licensing’: a multistep process

(2011) M Krampera   LEUKEMIA

Human MSC Suppression Correlates With Cytokine Induction of Indoleamine 2,3-Dioxygenase and Bystander M2 Macrophage Differentiation

(2011) Moïra François et al.   MOLECULAR THERAPY

Mesenchymal stem cell–based tissue regeneration is governed by recipient T lymphocytes via IFN-γ and TNF-α

(2011) Yi Liu et al.   NATURE MEDICINE

Human Adipose-Derived Stem Cells Impair Natural Killer Cell Function and Exhibit Low Susceptibility to Natural Killer-Mediated Lysis

(2011) Olga DelaRosa et al.   STEM CELLS AND DEVELOPMENT

Fibroblast growth factor 2 and platelet-derived growth factor, but not platelet lysate, induce proliferation-dependent, functional class II major histocompatibility complex antigen in human mesenchymal stem cells

(2010) Chiara Bocelli-Tyndall et al.   ARTHRITIS AND RHEUMATISM

Human multipotent mesenchymal stromal cells use galectin-1 to inhibit immune effector cells

(2010) F. Gieseke et al.   BLOOD

Fetal and adult multipotent mesenchymal stromal cells are killed by different pathways

(2010) Cecilia Götherström et al.   CYTOTHERAPY

Good Manufacturing Practices Production of Mesenchymal Stem/Stromal Cells

(2010) Luc Sensebé et al.   HUMAN GENE THERAPY

Stromal stem cells from adipose tissue and bone marrow of age-matched female donors display distinct immunophenotypic profiles

(2010) G. Pachón-Peña et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Enhanced Indoleamine 2,3‐Dioxygenase Activity in Patients with Severe Sepsis and Septic Shock

(2010) Pierre Tattevin et al.   JOURNAL OF INFECTIOUS DISEASES

Anti-inflammatory protein TSG-6 reduces inflammatory damage to the cornea following chemical and mechanical injury

(2010) J. Y. Oh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD40L induces inflammation and adipogenesis in adipose cells – a potential link between metabolic and cardiovascular disease

(2010) Isabel Platzer et al.   THROMBOSIS AND HAEMOSTASIS

Mesenchymal stromal cells cross-present soluble exogenous antigens as part of their antigen-presenting cell properties

(2009) M. Francois et al.   BLOOD

Clinical-grade production of human mesenchymal stromal cells: occurrence of aneuploidy without transformation

(2009) K. Tarte et al.   BLOOD

Functional Alteration of the Lymphoma Stromal Cell Niche by the Cytokine Context: Role of Indoleamine-2,3 Dioxygenase

(2009) H. Maby-El Hajjami et al.   CANCER RESEARCH

Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6

(2009) Ryang Hwa Lee et al.   Cell Stem Cell

Adipose tissue-derived mesenchymal stem cells are more potent suppressors of dendritic cells differentiation compared to bone marrow-derived mesenchymal stem cells

(2009) Ekaterina Ivanova-Todorova et al.   IMMUNOLOGY LETTERS

Adipose-Derived Mesenchymal Stem Cells Ameliorate Chronic Experimental Autoimmune Encephalomyelitis

(2009) Gabriela Constantin et al.   STEM CELLS

Species Variation in the Mechanisms of Mesenchymal Stem Cell-Mediated Immunosuppression

(2009) Guangwen Ren et al.   STEM CELLS

Human Alternatives to Fetal Bovine Serum for the Expansion of Mesenchymal Stromal Cells from Bone Marrow

(2009) Karen Bieback et al.   STEM CELLS

PDGF, TGF- , and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): transcriptional profiling can identify markers and signaling pathways important in differentiation of MSCs into adipogenic, chondrogenic, and osteogenic lineages

(2008) F. Ng et al.   BLOOD

Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide

(2008) Guangwen Ren et al.   Cell Stem Cell

IFN-γ activation of mesenchymal stem cells for treatment and prevention of graft versus host disease

(2008) David Polchert et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cell specific differences between human adipose-derived and mesenchymal–stromal cells despite similar differentiation potentials

(2008) Danièle Noël et al.   EXPERIMENTAL CELL RESEARCH

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

(2008) Katarina Le Blanc et al.   LANCET

Platelet-derived growth factor BB promotes the migration of bone marrow-derived mesenchymal stem cells towards C6 glioma and up-regulates the expression of intracellular adhesion molecule-1

(2008) Peng Cheng et al.   NEUROSCIENCE LETTERS

Toll-Like Receptors 3 and 4 Are Expressed by Human Bone Marrow-Derived Mesenchymal Stem Cells and Can Inhibit Their T-Cell Modulatory Activity by Impairing Notch Signaling

(2007) Francesco Liotta et al.   STEM CELLS

Bone Marrow-Derived Mesenchymal Stem Cells Induce Both Polyclonal Expansion and Differentiation of B Cells Isolated from Healthy Donors and Systemic Lupus Erythematosus Patients

(2007) Elisabetta Traggiai et al.   STEM CELLS

Human Leukocyte Antigen-G5 Secretion by Human Mesenchymal Stem Cells Is Required to Suppress T Lymphocyte and Natural Killer Function and to Induce CD4+CD25highFOXP3+Regulatory T Cells

(2007) Zohair Selmani et al.   STEM CELLS