Apoptotic Cell-Derived Extracellular Vesicles: More Than Just Debris

Extracellular Vesicle Subtypes Released From Activated or Apoptotic T-Lymphocytes Carry a Specific and Stimulus-Dependent Protein Cargo

(2018) Christine Tucher et al.   Frontiers in Immunology

Disassembly of the Dying: Mechanisms and Functions

(2017) Georgia K. Atkin-Smith et al.   TRENDS IN CELL BIOLOGY

Extracellular Vesicles Arising from Apoptotic Cells in Tumors: Roles in Cancer Pathogenesis and Potential Clinical Applications

(2017) Catherine Lynch et al.   Frontiers in Immunology

Digestion of Chromatin in Apoptotic Cell Microparticles Prevents Autoimmunity

(2016) Vanja Sisirak et al.   CELL

The CD169 sialoadhesin molecule mediates cytotoxic T-cell responses to tumour apoptotic vesicles

(2016) Lane VC Black et al.   IMMUNOLOGY AND CELL BIOLOGY

Monitoring the progression of cell death and the disassembly of dying cells by flow cytometry

(2016) Lanzhou Jiang et al.   Nature Protocols

Procoagulant and immunogenic properties of melanoma exosomes, microvesicles and apoptotic vesicles

(2016) Morad-Rémy Muhsin-Sharafaldine et al.   Oncotarget

Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets

(2016) Laurent Muller et al.   Scientific Reports

Apoptotic-cell-derived membrane microparticles and IFN-α induce an inflammatory immune response

(2015) Anna Niessen et al.   JOURNAL OF CELL SCIENCE

The 20 S proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection

(2015) Mélanie Dieudé et al.   Science Translational Medicine

A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure

(2015) Georgia K. Atkin-Smith et al.   Nature Communications

Microparticles Release by Adipocytes Act as “Find-Me” Signals to Promote Macrophage Migration

(2015) Akiko Eguchi et al.   PLoS One

Cancer treatment and survivorship statistics, 2014

(2014) Carol E. DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Loading of nuclear autoantigens prototypically recognized by systemic lupus erythematosus sera into late apoptotic vesicles requires intact microtubules and myosin light chain kinase activity

(2014) M. Zirngibl et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Unexpected link between an antibiotic, pannexin channels and apoptosis

(2014) Ivan K. H. Poon et al.   NATURE

Emerging role of extracellular vesicles in inflammatory diseases

(2014) Edit I. Buzas et al.   Nature Reviews Rheumatology

Body Fluid Exosomes Promote Secretion of Inflammatory Cytokines in Monocytic Cells via Toll-like Receptor Signaling

(2013) Niko P. Bretz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies

(2013) Johnny C. Akers et al.   JOURNAL OF NEURO-ONCOLOGY

Clearing the Dead: Apoptotic Cell Sensing, Recognition, Engulfment, and Digestion

(2013) A. Hochreiter-Hufford et al.   Cold Spring Harbor Perspectives in Biology

During apoptosis HMGB1 is translocated into apoptotic cell-derived membraneous vesicles

(2012) Martin Schiller et al.   AUTOIMMUNITY

Microparticles: major transport vehicles for distinct microRNAs in circulation

(2012) P. Diehl et al.   CARDIOVASCULAR RESEARCH

How apoptotic cells aid in the removal of their own cold dead bodies

(2012) G Wickman et al.   CELL DEATH AND DIFFERENTIATION

A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death

(2012) Abhishek D Garg et al.   EMBO JOURNAL

Apoptotic-cell-derived membrane vesicles induce an alternative maturation of human dendritic cells which is disturbed in SLE

(2012) Eva-Marie Fehr et al.   JOURNAL OF AUTOIMMUNITY

HIV-1 infection–induced apoptotic microparticles inhibit human DCs via CD44

(2012) Davor Frleta et al.   JOURNAL OF CLINICAL INVESTIGATION

Induction of Type I IFN Is a Physiological Immune Reaction to Apoptotic Cell-Derived Membrane Microparticles

(2012) M. Schiller et al.   JOURNAL OF IMMUNOLOGY

The recombinant tuberculosis vaccine rBCG ΔureC::hly+ induces apoptotic vesicles for improved priming of CD4+ and CD8+ T cells

(2012) Maura Farinacci et al.   VACCINE

Apoptotic cell-derived ICAM-3 promotes both macrophage chemoattraction to and tethering of apoptotic cells

(2011) E E Torr et al.   CELL DEATH AND DIFFERENTIATION

Macrophages Discriminate Glycosylation Patterns of Apoptotic Cell-derived Microparticles

(2011) Rostyslav O. Bilyy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microvesicles and Viral Infection

(2011) D. G. Meckes et al.   JOURNAL OF VIROLOGY

Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1 

(2011) Y. Berda-Haddad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autoimmunity and chronic inflammation — Two clearance-related steps in the etiopathogenesis of SLE

(2010) Luis E. Muñoz et al.   AUTOIMMUNITY REVIEWS

Decoding Cell Death Signals in Inflammation and Immunity

(2010) Laurence Zitvogel et al.   CELL

Autoimmunity and the Clearance of Dead Cells

(2010) Shigekazu Nagata et al.   CELL

Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses

(2010) Pascale Krejbich-Trotot et al.   FASEB JOURNAL

Mouse dendritic cells matured by ingestion of apoptotic blebs induce T cells to produce interleukin-17

(2009) Justin H. Fransen et al.   ARTHRITIS AND RHEUMATISM

Antigen-loaded exosomes alone induce Th1-type memory through a B cell-dependent mechanism

(2009) K. R. Qazi et al.   BLOOD

CX3CL1/fractalkine is released from apoptotic lymphocytes to stimulate macrophage chemotaxis

(2008) L. A. Truman et al.   BLOOD

The content of DNA and RNA in microparticles released by Jurkat and HL-60 cells undergoing in vitro apoptosis

(2008) Charles F. Reich et al.   EXPERIMENTAL CELL RESEARCH

Exosomes Derived from M. Bovis BCG Infected Macrophages Activate Antigen-Specific CD4+ and CD8+ T Cells In Vitro and In Vivo

(2008) Pramod K. Giri et al.   PLoS One