Distinct Immunomodulatory and Migratory Mechanisms Underpin the Therapeutic Potential of Human Mesenchymal Stem Cells in Autoimmune Demyelination

B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6–producing B cells

(2012) Tom A. Barr et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Thymic Gene Transfer of Myelin Oligodendrocyte Glycoprotein Ameliorates the Onset but Not the Progression of Autoimmune Demyelination

(2012) Christopher Siatskas et al.   MOLECULAR THERAPY

Mesenchymal Stem Cells Lack Efficacy in the Treatment of Experimental Autoimmune Neuritis despite In Vitro Inhibition of T-Cell Proliferation

(2012) Marija Sajic et al.   PLoS One

Comparative Study on the Therapeutic Potential of Neurally Differentiated Stem Cells in a Mouse Model of Multiple Sclerosis

(2012) Natalie L. Payne et al.   PLoS One

Mesenchymal Stem Cells: Mechanisms of Inflammation

(2011) Nora G. Singer et al.   Annual Review of Pathology-Mechanisms of Disease

Targeted Intra-arterial Transplantation of Stem Cells to the Injured CNS is more Effective than Intravenous Administration: Engraftment is Dependent on Cell Type and Adhesion Molecule Expression

(2011) Johan Lundberg et al.   CELL TRANSPLANTATION

Comparison of chemokine and receptor gene expression between Wharton's jelly and bone marrow-derived mesenchymal stromal cells

(2011) Sudha Balasubramanian et al.   CYTOTHERAPY

Cytokines and effector T cell subsets causing autoimmune CNS disease

(2011) Franziska Petermann et al.   FEBS LETTERS

Mesenchymal stromal cell ‘licensing’: a multistep process

(2011) M Krampera   LEUKEMIA

Bone Marrow-Derived Mesenchymal Stromal Cells Inhibit Th2-Mediated Allergic Airways Inflammation in Mice

(2011) Meagan Goodwin et al.   STEM CELLS

B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity

(2010) Martin S. Weber et al.   ANNALS OF NEUROLOGY

The blood–brain barrier, chemokines and multiple sclerosis

(2010) David W. Holman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Therapeutic Effects of Umbilical Cord Blood-Derived Mesenchymal Stem Cell Transplantation in Experimental Lupus Nephritis

(2010) Jei-Wen Chang et al.   CELL TRANSPLANTATION

Why should mesenchymal stem cells (MSCs) cure autoimmune diseases?

(2010) Antonio Uccelli et al.   CURRENT OPINION IN IMMUNOLOGY

Vascular inflammation in central nervous system diseases: adhesion receptors controlling leukocyte-endothelial interactions

(2010) B. Rossi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human Mesenchymal Stem Cells Infiltrate the Spinal Cord, Reduce Demyelination, and Localize to White Matter Lesions in Experimental Autoimmune Encephalomyelitis

(2010) David Gordon et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

(2010) Simón Méndez-Ferrer et al.   NATURE

Pro-Inflammatory Cytokines, IFNγ and TNFα, Influence Immune Properties of Human Bone Marrow and Wharton Jelly Mesenchymal Stem Cells Differentially

(2010) S. Jyothi Prasanna et al.   PLoS One

Interferon-γ and Tumor Necrosis Factor-α Differentially Affect Cytokine Expression and Migration Properties of Mesenchymal Stem Cells

(2010) Hatim Hemeda et al.   STEM CELLS AND DEVELOPMENT

Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T cell proliferation and collagen-induced arthritis

(2010) Evelien Schurgers et al.   ARTHRITIS RESEARCH & THERAPY

Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6

(2009) Ryang Hwa Lee et al.   Cell Stem Cell

Mesenchymal Stem Cell Homing: The Devil Is in the Details

(2009) Jeffrey M. Karp et al.   Cell Stem Cell

In vitro study of matrix metalloproteinase/tissue inhibitor of metalloproteinase production by mesenchymal stromal cells in response to inflammatory cytokines: the role of their migration in injured tissues

(2009) Tatiana Tondreau et al.   CYTOTHERAPY

Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis

(2009) Lianhua Bai et al.   GLIA

Adipose tissue-derived mesenchymal stem cells are more potent suppressors of dendritic cells differentiation compared to bone marrow-derived mesenchymal stem cells

(2009) Ekaterina Ivanova-Todorova et al.   IMMUNOLOGY LETTERS

Mesenchymal Stromal Cells Ameliorate Experimental Autoimmune Encephalomyelitis by Inhibiting CD4 Th17 T Cells in a CC Chemokine Ligand 2-Dependent Manner

(2009) Moutih Rafei et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Natalizumab Blocks Adhesion but Not Initial Contact of Human T Cells to the Blood-Brain Barrier In Vivo in an Animal Model of Multiple Sclerosis

(2009) Caroline Coisne et al.   JOURNAL OF IMMUNOLOGY

Immunomodulatory Function of Bone Marrow-Derived Mesenchymal Stem Cells in Experimental Autoimmune Type 1 Diabetes

(2009) P. Fiorina et al.   JOURNAL OF IMMUNOLOGY

Neuroprotective mesenchymal stem cells are endowed with a potent antioxidant effectin vivo

(2009) Cristina Lanza et al.   JOURNAL OF NEUROCHEMISTRY

Immunomodulatory treatment strategies in multiple sclerosis

(2009) Bernd C. Kieseier et al.   JOURNAL OF NEUROLOGY

Allogeneic Mesenchymal Stem Cells for Treatment of Experimental Autoimmune Encephalomyelitis

(2009) Moutih Rafei et al.   MOLECULAR THERAPY

Adipose-Derived Mesenchymal Stem Cells Ameliorate Chronic Experimental Autoimmune Encephalomyelitis

(2009) Gabriela Constantin et al.   STEM CELLS

Activation of Signal Transducers and Activators of Transcription 3 and Focal Adhesion Kinase by Stromal Cell-Derived Factor 1 Is Required for Migration of Human Mesenchymal Stem Cells in Response to Tumor Cell-Conditioned Medium

(2009) Hui Gao et al.   STEM CELLS

Functions and molecular mechanisms of the CD47–SIRPα signalling pathway

(2009) Takashi Matozaki et al.   TRENDS IN CELL BIOLOGY

Neuroprotection and Immunomodulation With Mesenchymal Stem Cells in Chronic Experimental Autoimmune Encephalomyelitis

(2008) Ibrahim Kassis et al.   ARCHIVES OF NEUROLOGY

Mesenchymal stem cells from human bone marrow or adipose tissue differently modulate mitogen-stimulated B-cell immunoglobulin production in vitro

(2008) Ivan Bochev et al.   CELL BIOLOGY INTERNATIONAL

A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs

(2008) Mihaela Crisan et al.   Cell Stem Cell

Cell specific differences between human adipose-derived and mesenchymal–stromal cells despite similar differentiation potentials

(2008) Danièle Noël et al.   EXPERIMENTAL CELL RESEARCH

Mesenchymal cells recruit and regulate T regulatory cells

(2008) M DIIANNI   EXPERIMENTAL HEMATOLOGY

Chemokine signaling and integrin activation in lymphocyte migration into the inflamed brain

(2008) Gabriela Constantin   JOURNAL OF NEUROIMMUNOLOGY

Human mesenchymal stem cells abrogate experimental allergic encephalomyelitis after intraperitoneal injection, and with sparse CNS infiltration

(2008) David Gordon et al.   NEUROSCIENCE LETTERS

Molecular Trafficking Mechanisms of Multipotent Mesenchymal Stem Cells Derived from Human Bone Marrow and Placenta

(2008) Gary Brooke et al.   STEM CELLS AND DEVELOPMENT

Pulmonary Passage is a Major Obstacle for Intravenous Stem Cell Delivery: The Pulmonary First-Pass Effect

(2008) Uwe M. Fischer et al.   STEM CELLS AND DEVELOPMENT