Nutrigenomics of extra-virgin olive oil: A review

Oleuropein Mediated Targeting of Signaling Network in Cancer

(2016) Sundas Fayyaz et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

a-13'-OH is the main product of a-tocopherol metabolism and influences CYP4F2 and PPAR? gene expression in HepG2 human hepatocarcinoma cells

(2016) Pierangelo Torquato et al.   FREE RADICAL BIOLOGY AND MEDICINE

The functional interactome of GSTP: A regulatory biomolecular network at the interface with the Nrf2 adaption response to oxidative stress

(2016) Desirée Bartolini et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Analytical strategies to assess the functional metabolome of vitamin E

(2016) Pierangelo Torquato et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

The role of lipid droplet formation in the protection of unsaturated fatty acids against palmitic acid induced lipotoxicity to rat insulin-producing cells

(2016) Thomas Plötz et al.   Nutrition & Metabolism

Unsuccessful Detection of Plant MicroRNAs in Beer, Extra Virgin Olive Oil and Human Plasma After an Acute Ingestion of Extra Virgin Olive Oil

(2016) Victor Micó et al.   PLANT FOODS FOR HUMAN NUTRITION

Potential Diagnostic and Prognostic Biomarkers of Epigenetic Drift within the Cardiovascular Compartment

(2016) Robert G. Wallace et al.   Biomed Research International

Dietary phytochemicals and neuro-inflammaging: from mechanistic insights to translational challenges

(2016) Sergio Davinelli et al.   Immunity & Ageing

Gain of survival signaling by down-regulation of three key miRNAs in brain of calorie-restricted mice

(2016) Amit Khanna et al.   Aging-US

ChREBP Regulates Itself and Metabolic Genes Implicated in Lipid Accumulation in β–Cell Line

(2016) Chanachai Sae-Lee et al.   PLoS One

Vitamin E function and requirements in relation to PUFA

(2015) Daniel Raederstorff et al.   BRITISH JOURNAL OF NUTRITION

Virgin olive oil: a key food for cardiovascular risk protection

(2015) María-Isabel Covas et al.   BRITISH JOURNAL OF NUTRITION

A nutrigenomics approach for the study of anti-aging interventions: olive oil phenols and the modulation of gene and microRNA expression profiles in mouse brain

(2015) Cristina Luceri et al.   EUROPEAN JOURNAL OF NUTRITION

Effect of olive oil phenolic compounds on the expression of blood pressure-related genes in healthy individuals

(2015) Sandra Martín-Peláez et al.   EUROPEAN JOURNAL OF NUTRITION

Reaction kinetics and targeting to cellular glutathione S-transferase of the glutathione peroxidase mimetic PhSeZnCl and its d,l-polylactide microparticle formulation

(2015) D. Bartolini et al.   FREE RADICAL BIOLOGY AND MEDICINE

Human serum determination and in vitro anti-inflammatory activity of the vitamin E metabolite α-(13'-hydroxy)-6-hydroxychroman

(2015) Silvia Ciffolilli et al.   FREE RADICAL BIOLOGY AND MEDICINE

Glutathione S-transferase pi expression regulates the Nrf2-dependent response to hormetic diselenides

(2015) D. Bartolini et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of Hypoxia-Inducible Factor-1a by Reactive Oxygen Species : New Developments in an Old Debate

(2015) Shahrzad Movafagh et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Hydroxytyrosol-Derived Compounds: A Basis for the Creation of New Pharmacological Agents for Cancer Prevention and Therapy

(2015) Roberta Bernini et al.   JOURNAL OF MEDICINAL CHEMISTRY

Effect of Erythrodiol, A Natural Pentacyclic Triterpene from Olive Oil, on the Lipid Membrane Properties

(2015) Lamice Habib et al.   JOURNAL OF MEMBRANE BIOLOGY

Intervention Trials with the Mediterranean Diet in Cardiovascular Prevention: Understanding Potential Mechanisms through Metabolomic Profiling

(2015) Miguel Á Martínez-González et al.   JOURNAL OF NUTRITION

α-Tocopherol long-chain metabolite α-13’-COOH affects the inflammatory response of lipopolysaccharide-activated murine RAW264.7 macrophages

(2015) Maria Wallert et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Dose effect on the uptake and accumulation of hydroxytyrosol and its metabolites in target tissues in rats

(2015) Maria-Carmen López de las Hazas et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Chemopreventive effect of oleuropein in colitis-associated colorectal cancer in c57bl/6 mice

(2015) Elisa Giner et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Potential Role of Olive Oil Phenolic Compounds in the Prevention of Neurodegenerative Diseases

(2015) Jose Rodríguez-Morató et al.   MOLECULES

Vascular actions of 20-HETE

(2015) Samantha L. Hoopes et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

The hydroxytyrosol-dependent increase of TNF-α in LPS-activated human monocytes is mediated by PGE2 and adenylate cyclase activation

(2015) R. Fuccelli et al.   TOXICOLOGY IN VITRO

Food derived microRNAs

(2015) Anika E. Wagner et al.   Food & Function

Inflammaging and Cancer: A Challenge for the Mediterranean Diet

(2015) Rita Ostan et al.   Nutrients

Consumption of Distinct Dietary Lipids during Early Pregnancy Differentially Modulates the Expression of microRNAs in Mothers and Offspring

(2015) Patricia Casas-Agustench et al.   PLoS One

Impact of Virgin Olive Oil and Phenol-Enriched Virgin Olive Oils on the HDL Proteome in Hypercholesterolemic Subjects: A Double Blind, Randomized, Controlled, Cross-Over Clinical Trial (VOHF Study)

(2015) Anna Pedret et al.   PLoS One

Additive Regulation of Adiponectin Expression by the Mediterranean Diet Olive Oil Components Oleic Acid and Hydroxytyrosol in Human Adipocytes

(2015) Egeria Scoditti et al.   PLoS One

Impact of a 6-wk olive oil supplementation in healthy adults on urinary proteomic biomarkers of coronary artery disease, chronic kidney disease, and diabetes (types 1 and 2): a randomized, parallel, controlled, double-blind study

(2014) Sandra Silva et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Membrane composition and dynamics: A target of bioactive virgin olive oil constituents

(2014) Sergio Lopez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Sequestration of fatty acids in triglycerides prevents endoplasmic reticulum stress in an in vitro model of cardiomyocyte lipotoxicity

(2014) Madeleen Bosma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Squalene oxidation products: Monitoring the formation, characterisation and pro-oxidant activity

(2014) Eleni Naziri et al.   EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY

Differential protective effects of extra virgin olive oil and corn oil in liver injury: A proteomic study

(2014) Hualin Wang et al.   FOOD AND CHEMICAL TOXICOLOGY

Natural forms of vitamin E: metabolism, antioxidant, and anti-inflammatory activities and their role in disease prevention and therapy

(2014) Qing Jiang   FREE RADICAL BIOLOGY AND MEDICINE

Hydroxytyrosol and Its Potential Therapeutic Effects

(2014) Ting Hu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

MicroRNAs Are Absorbed in Biologically Meaningful Amounts from Nutritionally Relevant Doses of Cow Milk and Affect Gene Expression in Peripheral Blood Mononuclear Cells, HEK-293 Kidney Cell Cultures, and Mouse Livers

(2014) Scott R. Baier et al.   JOURNAL OF NUTRITION

Metabolomic Pattern Analysis after Mediterranean Diet Intervention in a Nondiabetic Population: A 1- and 3-Year Follow-up in the PREDIMED Study

(2014) Rosa Vázquez-Fresno et al.   JOURNAL OF PROTEOME RESEARCH

A Think Tank of TINK/TANKs: Tumor-Infiltrating/Tumor-Associated Natural Killer Cells in Tumor Progression and Angiogenesis

(2014) Antonino Bruno et al.   JNCI-Journal of the National Cancer Institute

Dietary squalene supplementation improves DSS-induced acute colitis by downregulating p38 MAPK and NFkB signaling pathways

(2014) Susana Sánchez-Fidalgo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance

(2014) Antonina V. Kurtova et al.   NATURE

Chronic hydroxytyrosol feeding modulates glutathione-mediated oxido-reduction pathways in adipose tissue: A nutrigenomic study

(2014) E. Giordano et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Olive Phenolics as c-Met Inhibitors: (-)-Oleocanthal Attenuates Cell Proliferation, Invasiveness, and Tumor Growth in Breast Cancer Models

(2014) Mohamed R. Akl et al.   PLoS One

Consumption of extra-virgin olive oil rich in phenolic compounds has beneficial antioxidant effects in healthy human adults

(2014) María-Jesús Oliveras-López et al.   Journal of Functional Foods

Oleuropein inhibits tumour growth and metastases dissemination in ovariectomised nude mice with MCF-7 human breast tumour xenografts

(2014) Maria Vittoria Sepporta et al.   Journal of Functional Foods

In vivo distribution and deconjugation of hydroxytyrosol phase II metabolites in red blood cells: A potential new target for hydroxytyrosol

(2014) Laura Rubió et al.   Journal of Functional Foods

Regulatory metabolites of vitamin E and their putative relevance for atherogenesis

(2014) Maria Wallert et al.   Redox Biology

In vivo transcriptomic profile after a Mediterranean diet in high–cardiovascular risk patients: a randomized controlled trial

(2013) et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

In vivo regulation of gene transcription by alpha- and gamma-tocopherol in murine T lymphocytes

(2013) Jean-Marc Zingg et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Extra virgin olive oil (EVOO) consumption and antioxidant status in healthy institutionalized elderly humans

(2013) María-Jesús Oliveras-López et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Mitochondrial-dependent anticancer activity of δ-tocotrienol and its synthetic derivatives in HER-2/neu overexpressing breast adenocarcinoma cells

(2013) Valentina Viola et al.   BIOFACTORS

Effect of annatto-tocotrienols supplementation on the development of mammary tumors in HER-2/neu transgenic mice

(2013) E. Pierpaoli et al.   CARCINOGENESIS

NF-κβ signaling and chronic inflammatory diseases: exploring the potential of natural products to drive new therapeutic opportunities

(2013) Matthew J. Killeen et al.   DRUG DISCOVERY TODAY

Olive oil compounds inhibit vascular endothelial growth factor receptor-2 phosphorylation

(2013) Sylvie Lamy et al.   EXPERIMENTAL CELL RESEARCH

Lipokines and oxysterols: Novel adipose-derived lipid hormones linking adipose dysfunction and insulin resistance

(2013) Giuseppe Murdolo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Long-chain metabolites of α-tocopherol occur in human serum and inhibit macrophage foam cell formation in vitro

(2013) Maria Wallert et al.   FREE RADICAL BIOLOGY AND MEDICINE

How do nutritional antioxidants really work: Nucleophilic tone and para-hormesis versus free radical scavenging in vivo

(2013) Henry J. Forman et al.   FREE RADICAL BIOLOGY AND MEDICINE

Bioactive Properties of the Main Triterpenes Found in Olives, Virgin Olive Oil, and Leaves of Olea europaea

(2013) Cristina Sánchez-Quesada et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Normalizing Tumor Microenvironment to Treat Cancer: Bench to Bedside to Biomarkers

(2013) Rakesh K. Jain   JOURNAL OF CLINICAL ONCOLOGY

Effect of olive oil phenols on the production of inflammatory mediators in freshly isolated human monocytes

(2013) Patrizia Rosignoli et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Tocopherol Activity Correlates with Its Location in a Membrane: A New Perspective on the Antioxidant Vitamin E

(2013) Drew Marquardt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Health effects of olive oil polyphenols: Recent advances and possibilities for the use of health claims

(2013) Sandra Martín-Peláez et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Up-to date knowledge on the in vivo transcriptomic effect of the Mediterranean diet in humans

(2013) Valentini Konstantinidou et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Primary Prevention of Cardiovascular Disease with a Mediterranean Diet

(2013) Ramón Estruch et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pinoresinol Inhibits Proliferation and Induces Differentiation on Human HL60 Leukemia Cells

(2013) Maria Vittoria Sepporta et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Oleuropein and oleacein may restore biological functions of endothelial progenitor cells impaired by angiotensin II via activation of Nrf2/heme oxygenase-1 pathway

(2013) Andrzej Parzonko et al.   PHYTOMEDICINE

Mediterranean diet and health status: an updated meta-analysis and a proposal for a literature-based adherence score

(2013) Francesco Sofi et al.   PUBLIC HEALTH NUTRITION

Vascular Normalization as a Therapeutic Strategy for Malignant and Nonmalignant Disease

(2013) S. Goel et al.   Cold Spring Harbor Perspectives in Medicine

Protection of LDL from oxidation by olive oil polyphenols is associated with a downregulation of CD40-ligand expression and its downstream products in vivo in humans

(2012) Olga Castañer et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Olive oil intake and mortality within the Spanish population (EPIC-Spain)

(2012) Genevieve Buckland et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Mediterranean diet polyphenols reduce inflammatory angiogenesis through MMP-9 and COX-2 inhibition in human vascular endothelial cells: A potentially protective mechanism in atherosclerotic vascular disease and cancer

(2012) Egeria Scoditti et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Glutathione peroxidases

(2012) Regina Brigelius-Flohé et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Identification of the factors responsible for the in vitro pro-oxidant and cytotoxic activities of the olive polyphenols oleuropein and hydroxytyrosol

(2012) Elena M. Odiatou et al.   CANCER LETTERS

Diet-derived polyphenols inhibit angiogenesis by modulating the interleukin-6/STAT3 pathway

(2012) Sylvie Lamy et al.   EXPERIMENTAL CELL RESEARCH

Phenols of virgin olive oil protects nuclear DNA against oxidative damage in HeLa cells

(2012) Özlem Erol et al.   FOOD AND CHEMICAL TOXICOLOGY

Valuable Nutrients and Functional Bioactives in Different Parts of Olive (Olea europaea L.)—A Review

(2012) Rahele Ghanbari et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Disruption of Mouse Cytochrome P450 4f14 (Cyp4f14Gene) Causes Severe Perturbations in Vitamin E Metabolism

(2012) Sabrina A. Bardowell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Olive oil phenolics: Where do we stand? Where should we go?

(2012) Francesco Visioli   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Effects of polyphenol extract from olive pomace on anoxia-induced endothelial dysfunction

(2012) Daniela Palmieri et al.   MICROVASCULAR RESEARCH

Potential of olive oil phenols as chemopreventive and therapeutic agents against cancer: A review of in vitro studies

(2012) Ivan Casaburi et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Cancer prevention by targeting angiogenesis

(2012) Adriana Albini et al.   Nature Reviews Clinical Oncology

Comprehensive Analysis of Polyphenols in 55 Extra Virgin Olive Oils by HPLC-ECD and Their Correlation with Antioxidant Activities

(2012) Banu Bayram et al.   PLANT FOODS FOR HUMAN NUTRITION

Predicting Candidate Genes Based on Combined Network Topological Features: A Case Study in Coronary Artery Disease

(2012) Liangcai Zhang et al.   PLoS One

Long-Term Dietary Extra-Virgin Olive Oil Rich in Polyphenols Reverses Age-Related Dysfunctions in Motor Coordination and Contextual Memory in Mice: Role of Oxidative Stress

(2012) Vanessa Pitozzi et al.   REJUVENATION RESEARCH

A Diet Rich in Olive Oil Phenolics Reduces Oxidative Stress in the Heart of SAMP8 Mice by Induction of Nrf2-Dependent Gene Expression

(2012) Banu Bayram et al.   REJUVENATION RESEARCH

Multifaceted roles of PGE2 in inflammation and cancer

(2012) Masako Nakanishi et al.   Seminars in Immunopathology

Red wine polyphenolics reduce the expression of inflammation markers in human colon-derived CCD-18Co myofibroblast cells: Potential role of microRNA-126

(2012) Gabriela Angel-Morales et al.   Food & Function

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA

(2011) Lin Zhang et al.   CELL RESEARCH

Hydroxytyrosol glucuronides protect renal tubular epithelial cells against H2O2 induced oxidative damage

(2011) Monica Deiana et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Oleic Acid in Olive Oil: From a Metabolic Framework Toward a Clinical Perspective

(2011) Beatriz Bermudez et al.   CURRENT PHARMACEUTICAL DESIGN

microRNA-34c is a novel target to treat dementias

(2011) Athanasios Zovoilis et al.   EMBO JOURNAL

Hydrophilic antioxidants of virgin olive oil. Part 1: Hydrophilic phenols: A key factor for virgin olive oil quality

(2011) Milad El Riachy et al.   EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY

Anti-proliferative and pro-apoptotic activities of hydroxytyrosol on different tumour cells: the role of extracellular production of hydrogen peroxide

(2011) Roberto Fabiani et al.   EUROPEAN JOURNAL OF NUTRITION

Maslinic acid, a natural triterpenoid compound from Olea europaea, protects cortical neurons against oxygen–glucose deprivation-induced injury

(2011) Yisong Qian et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Why tocotrienols work better: insights into the in vitro anti-cancer mechanism of vitamin E

(2011) Valentina Viola et al.   Genes and Nutrition

Investigation into the biological properties of the olive polyphenol, hydroxytyrosol: mechanistic insights by genome-wide mRNA-Seq analysis

(2011) Haloom Rafehi et al.   Genes and Nutrition

Stimulation of GSH synthesis to prevent oxidative stress-induced apoptosis by hydroxytyrosol in human retinal pigment epithelial cells: activation of Nrf2 and JNK-p62/SQSTM1 pathways

(2011) Xuan Zou et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Vitamin E, signalosomes and gene expression in T cells

(2011) Alberto Molano et al.   MOLECULAR ASPECTS OF MEDICINE

Distribution of olive oil phenolic compounds in rat tissues after administration of a phenolic extract from olive cake

(2011) Aida Serra et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Breaking the ‘harmony’ of TNF-α signaling for cancer treatment

(2011) S P Sasi et al.   ONCOGENE

Hydroxytyrosol Is the Major Anti-Inflammatory Compound in Aqueous Olive Extracts and Impairs Cytokine and Chemokine Production in Macrophages

(2011) Nathalie Richard et al.   PLANTA MEDICA

(−)-Oleocanthal as a c-Met Inhibitor for the Control of Metastatic Breast and Prostate Cancers

(2011) Ahmed Elnagar et al.   PLANTA MEDICA

High-Throughput Sequencing of RNA Silencing-Associated Small RNAs in Olive (Olea europaea L.)

(2011) Livia Donaire et al.   PLoS One

Effects of dietary extra-virgin olive oil on behaviour and brain biochemical parameters in ageing rats

(2010) Vanessa Pitozzi et al.   BRITISH JOURNAL OF NUTRITION

Anticancer Activity of Vitamin E-Derived Compounds in Murine C6 Glioma Cells

(2010) Francesco Mazzini et al.   ChemMedChem

Inhibition of Hypoxia Inducible Factor-1  by Dihydroxyphenylethanol, a Product from Olive Oil, Blocks Microsomal Prostaglandin-E Synthase-1/Vascular Endothelial Growth Factor Expression and Reduces Tumor Angiogenesis

(2010) E. Terzuoli et al.   CLINICAL CANCER RESEARCH

The Color of Olive Oils: The Pigments and Their Likely Health Benefits and Visual and Instrumental Methods of Analysis

(2010) María José Moyano et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Astrocytic glutamate transporter-dependent neuroprotection against glutamate toxicity: An in vitro study of maslinic acid

(2010) Yisong Qian et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

In vivo nutrigenomic effects of virgin olive oil polyphenols within the frame of the Mediterranean diet: a randomized controlled trial

(2010) Valentini Konstantinidou et al.   FASEB JOURNAL

Squalene protects against oxidative DNA damage in MCF10A human mammary epithelial cells but not in MCF7 and MDA-MB-231 human breast cancer cells

(2010) Fernando Warleta et al.   FOOD AND CHEMICAL TOXICOLOGY

Proapoptotic effects of long-chain vitamin E metabolites in HepG2 cells are mediated by oxidative stress

(2010) Marc Birringer et al.   FREE RADICAL BIOLOGY AND MEDICINE

Modulation of gene expression by α-tocopherol and α-tocopheryl phosphate in THP-1 monocytes

(2010) Jean-Marc Zingg et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive oxygen species in cancer

(2010) Geou-Yarh Liou et al.   FREE RADICAL RESEARCH

MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain

(2010) M. Somel et al.   GENOME RESEARCH

Hydroxytyrosol induces antioxidant/detoxificant enzymes and Nrf2 translocation via extracellular regulated kinases and phosphatidylinositol-3-kinase/protein kinase B pathways in HepG2 cells

(2010) María Angeles Martín et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Dietary α-tocopherol and neuromuscular health: Search for optimal dose and molecular mechanisms continues!

(2010) Kishorchandra Gohil et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Vitamin E and neurological function

(2010) David P. R. Muller   MOLECULAR NUTRITION & FOOD RESEARCH

The location and behavior of α-tocopherol in membranes

(2010) Jeffrey Atkinson et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Hydroxytyrosol: from laboratory investigations to future clinical trials

(2010) Sergio Granados-Principal et al.   NUTRITION REVIEWS

Human absorption of a supplement containing purified hydroxytyrosol, a natural antioxidant from olive oil, and evidence for its transient association with low-density lipoproteins

(2010) Maria González-Santiago et al.   PHARMACOLOGICAL RESEARCH

Gene expression profiling of aging in multiple mouse strains: identification of aging biomarkers and impact of dietary antioxidants

(2009) Sang-Kyu Park et al.   AGING CELL

Suppressive Effects of Hydroxytyrosol on Oxidative Stress and Nuclear Factor-κB Activation in THP-1 Cells

(2009) Xiaomei Zhang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Role of MCP-1 in cardiovascular disease: molecular mechanisms and clinical implications

(2009) Jianli Niu et al.   CLINICAL SCIENCE

Virgin olive oil as a fundamental nutritional component and skin protector

(2009) Publio Viola et al.   CLINICS IN DERMATOLOGY

Anticancer effects of phytosterols

(2009) T A Woyengo et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

A 3 years follow-up of a Mediterranean diet rich in virgin olive oil is associated with high plasma antioxidant capacity and reduced body weight gain

(2009) C Razquin et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Metabolic regulation and redox activity as mechanisms for angioprevention by dietary phytochemicals

(2009) Francesca Tosetti et al.   INTERNATIONAL JOURNAL OF CANCER

Olive Phenolics Increase Glutathione Levels in Healthy Volunteers

(2009) Francesco Visioli et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Olive Oil Phenolic Compounds Inhibit Homocysteine-Induced Endothelial Cell Adhesion Regardless of Their Different Antioxidant Activity

(2009) Caterina Manna et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Synthesis, Biological Evaluation, and Molecular Modeling of Oleuropein and Its Semisynthetic Derivatives as Cyclooxygenase Inhibitors

(2009) Antonio Procopio et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Hepatic Lipid Partitioning and Liver Damage in Nonalcoholic Fatty Liver Disease

(2009) Zheng Zheng Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Production of hydrogen peroxide is responsible for the induction of apoptosis by hydroxytyrosol on HL60 cells

(2009) Roberto Fabiani et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Hydroxytyrosol inhibits pro-inflammatory cytokines, iNOS, and COX-2 expression in human monocytic cells

(2009) Xiaomei Zhang et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Biosynthesis, regulation and functions of tocochromanols in plants

(2009) Laurent Mène-Saffrané et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Phenolic compounds in olive oil: antioxidant, health and organoleptic activities according to their chemical structure

(2009) M. Servili et al.   INFLAMMOPHARMACOLOGY

Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species

(2008) Hideki Sumimoto   FEBS Journal

γ-Tocopheryl quinone, notα-tocopheryl quinone, induces adaptive response through up-regulation of cellular glutathione and cysteine availability via activation of ATF4

(2008) Yoko Ogawa et al.   FREE RADICAL RESEARCH

Nutritional Benefit of Olive Oil: The Biological Effects of Hydroxytyrosol and Its Arylating Quinone Adducts

(2008) David G. Cornwell et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Resolution of Non–Small-Cell Lung Cancer after Withdrawal of Anti-TNF Therapy

(2008) Charles W. Lees et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bioavailability of olive oil phenolic compounds in humans

(2008) R. de la Torre   INFLAMMOPHARMACOLOGY