Regulation of Hypoxia-Inducible Factor-1a by Reactive Oxygen Species : New Developments in an Old Debate

Evaluation of hypoxia inducible factor expression in inflammatory and neurodegenerative brain models

(2013) Maria Luisa de Lemos et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Reactive oxygen species-responsive miR-210 regulates proliferation and migration of adipose-derived stem cells via PTPN2

(2013) J H Kim et al.   Cell Death & Disease

MicroRNA-21 Modulates the Levels of Reactive Oxygen Species by Targeting SOD3 and TNF 

(2012) X. Zhang et al.   CANCER RESEARCH

The FIH hydroxylase is a cellular peroxide sensor that modulates HIF transcriptional activity

(2012) Norma Masson et al.   EMBO REPORTS

Inhibition of endothelial nitric oxyde synthase increases capillary formation via Rac1-dependent induction of hypoxia-inducible factor-1α and plasminogen activator inhibitor-1

(2012) A. Petry et al.   THROMBOSIS AND HAEMOSTASIS

Phosphatidylinositol 3′-kinase signaling pathway is essential for Rac1-induced hypoxia-inducible factor-1α and vascular endothelial growth factor expression

(2011) Yan Xue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

microRNA-210 is upregulated in hypoxic cardiomyocytes through Akt- and p53-dependent pathways and exerts cytoprotective effects

(2011) R. Kannan Mutharasan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Genomic instability induced by mutant succinate dehydrogenase subunit D (SDHD) is mediated by O2-• and H2O2

(2011) Kjerstin M. Owens et al.   FREE RADICAL BIOLOGY AND MEDICINE

PI3K and ERK-Induced Rac1 Activation Mediates Hypoxia-Induced HIF-1α Expression in MCF-7 Breast Cancer Cells

(2011) Jun Du et al.   PLoS One

miR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activity

(2010) M-P Puisségur et al.   CELL DEATH AND DIFFERENTIATION

Reactive oxygen species produced by the knockdown of manganese-superoxide dismutase up-regulate hypoxia-inducible factor-1α expression in oral squamous cell carcinoma cells

(2010) Eri Sasabe et al.   FREE RADICAL BIOLOGY AND MEDICINE

Stabilization of Hypoxia-inducible Factor-1α Protein in Hypoxia Occurs Independently of Mitochondrial Reactive Oxygen Species Production

(2010) Yee Liu Chua et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The cellular response to hypoxia: tuning the system with microRNAs

(2010) Joseph Loscalzo   JOURNAL OF CLINICAL INVESTIGATION

Reactive Oxygen Species-generating Mitochondrial DNA Mutation Up-regulates Hypoxia-inducible Factor-1α Gene Transcription via Phosphatidylinositol 3-Kinase-Akt/Protein Kinase C/Histone Deacetylase Pathway

(2009) Nobuko Koshikawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of MicroRNAs in Hydrogen Peroxide-mediated Gene Regulation and Cellular Injury Response in Vascular Smooth Muscle Cells

(2009) Ying Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-Inducible mir-210 Regulates Normoxic Gene Expression Involved in Tumor Initiation

(2009) Xin Huang et al.   MOLECULAR CELL

Manganese Superoxide Dismutase Modulates Hypoxia-Inducible Factor-1  Induction via Superoxide

(2008) S. Kaewpila et al.   CANCER RESEARCH