Reactive oxygen species in cancer

Hypoxic regulation of mRNA expression

(2011) Lawrence Gardner et al.   CELL CYCLE

Synergy of pancratistatin and tamoxifen on breast cancer cells in inducing apoptosis by targeting mitochondria

(2010) Peter Siedlakowski et al.   CANCER BIOLOGY & THERAPY

Mitochondrial electron transport chain blockers enhance 2-deoxy-D-glucose induced oxidative stress and cell killing in human colon carcinoma cells

(2010) Melissa A. Fath et al.   CANCER BIOLOGY & THERAPY

Inflammation and Liver Cancer

(2009) C. Berasain et al.   Annals of the New York Academy of Sciences

Antioxidants block proteasome inhibitor function in endometrial carcinoma cells

(2009) David Llobet et al.   ANTI-CANCER DRUGS

Redox-Based Escape Mechanism from Death: The Cancer Lesson

(2009) Giovambattista Pani et al.   ANTIOXIDANTS & REDOX SIGNALING

Reactive oxygen species and peroxisomes: Struggling for balance

(2009) Nina A. Bonekamp et al.   BIOFACTORS

Mitochondrial Dysfunction and Reactive Oxygen Species Imbalance Promote Breast Cancer Cell Motility through a CXCL14-Mediated Mechanism

(2009) H. Pelicano et al.   CANCER RESEARCH

4-Hydroxyestradiol Induces Anchorage-Independent Growth of Human Mammary Epithelial Cells via Activation of I B Kinase: Potential Role of Reactive Oxygen Species

(2009) S.-A. Park et al.   CANCER RESEARCH

Mitochondrial diacylglycerol initiates protein-kinase-D1-mediated ROS signaling

(2009) C. F. Cowell et al.   JOURNAL OF CELL SCIENCE

FOXO3a Promotes Tumor Cell Invasion through the Induction of Matrix Metalloproteinases

(2009) P. Storz et al.   MOLECULAR AND CELLULAR BIOLOGY

Reactive Oxygen Species Regulate a Slingshot-Cofilin Activation Pathway

(2009) Jun-Sub Kim et al.   MOLECULAR BIOLOGY OF THE CELL

Association of reactive oxygen species levels and radioresistance in cancer stem cells

(2009) Maximilian Diehn et al.   NATURE

Protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility through slingshot

(2009) Tim Eiseler et al.   NATURE CELL BIOLOGY

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Redox regulation of anoikis resistance of metastatic prostate cancer cells: key role for Src and EGFR-mediated pro-survival signals

(2009) E Giannoni et al.   ONCOGENE

Epigenetic Silencing of MicroRNA miR-107 Regulates Cyclin-Dependent Kinase 6 Expression in Pancreatic Cancer

(2009) Kwang-Hyuck Lee et al.   PANCREATOLOGY

Sulindac Enhances the Killing of Cancer Cells Exposed to Oxidative Stress

(2009) Maria Marchetti et al.   PLoS One

Mitochondrial Complex II Dysfunction Can Contribute Significantly to Genomic Instability after Exposure to Ionizing Radiation

(2009) Disha Dayal et al.   RADIATION RESEARCH

Tks5-Dependent, Nox-Mediated Generation of Reactive Oxygen Species Is Necessary for Invadopodia Formation

(2009) B. Diaz et al.   Science Signaling

Manganese superoxide dismutase activity regulates transitions between quiescent and proliferative growth

(2008) Ehab H. Sarsour et al.   AGING CELL

Oxidative stress stimulates skeletal muscle glucose uptake through a phosphatidylinositol 3-kinase-dependent pathway

(2008) Yasuki Higaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway

(2008) Ruifen Zhang et al.   APOPTOSIS

PKD prevents H2O2-induced apoptosis via NF-κB and p38 MAPK in RIE-1 cells

(2008) Jun Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Increased levels of superoxide and H2O2mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation

(2008) Nùkhet Aykin-Burns et al.   BIOCHEMICAL JOURNAL

Pharmacology of a mimetic of glutathione disulfide, NOV-002

(2008) Danyelle M. Townsend et al.   BIOMEDICINE & PHARMACOTHERAPY

Triphala inhibits both in vitro and in vivo xenograft growth of pancreatic tumor cells by inducing apoptosis

(2008) Yan Shi et al.   BMC CANCER

Novel 2-step synthetic indole compound 1,1,3-tri(3-indolyl)cyclohexane inhibits cancer cell growth in lung cancer cells and xenograft models

(2008) Ching-Hsiao Lee et al.   CANCER

RAC1 activity and intracellular ROS modulate the migratory potential of MCF-7 cells through a NADPH oxidase and NFκB-dependent mechanism

(2008) Nicolás Tobar et al.   CANCER LETTERS

Oxidative stress, DNA methylation and carcinogenesis

(2008) Rodrigo Franco et al.   CANCER LETTERS

Oxidative Stress Is Inherent in Prostate Cancer Cells and Is Required for Aggressive Phenotype

(2008) B. Kumar et al.   CANCER RESEARCH

Loss of MKP3 mediated by oxidative stress enhances tumorigenicity and chemoresistance of ovarian cancer cells

(2008) David W. Chan et al.   CARCINOGENESIS

Base excision repair of oxidative DNA damage and association with cancer and aging

(2008) S. Maynard et al.   CARCINOGENESIS

Cancer Cell Metabolism: Warburg and Beyond

(2008) Peggy P. Hsu et al.   CELL

The IκB kinase – a bridge between inflammation and cancer

(2008) Michael Karin   CELL RESEARCH

Lipid peroxidation of membrane phospholipids generates hydroxy-alkenals and oxidized phospholipids active in physiological and/or pathological conditions

(2008) Angel Catalá   CHEMISTRY AND PHYSICS OF LIPIDS

The Role of Reactive Oxygen Species in Integrin and Matrix Metalloproteinase Expression and Function

(2008) Gunbjørg Svineng et al.   CONNECTIVE TISSUE RESEARCH

Fibroblast growth factor regulation of neovascularization

(2008) Masahiro Murakami et al.   CURRENT OPINION IN HEMATOLOGY

PTEN deletion leads to deregulation of antioxidants and increased oxidative damage in mouse embryonic fibroblasts

(2008) Yan-Ying Huo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Epigenetic silencing of SOD2 by histone modifications in human breast cancer cells

(2008) Michael J. Hitchler et al.   FREE RADICAL BIOLOGY AND MEDICINE

Combination regimen with statins and NSAIDs: A promising strategy for cancer chemoprevention

(2008) Hang Xiao et al.   INTERNATIONAL JOURNAL OF CANCER

From anchorage dependent proliferation to survival: Lessons from redox signalling

(2008) Paola Chiarugi   IUBMB LIFE

Hyaluronan-mediated CD44 Interaction with p300 and SIRT1 Regulates β-Catenin Signaling and NFκB-specific Transcription Activity Leading to MDR1 and Bcl-xLGene Expression and Chemoresistance in Breast Tumor Cells

(2008) Lilly Y. W. Bourguignon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Rac activator Tiam1 prevents keratinocyte apoptosis by controlling ROS-mediated ERK phosphorylation

(2008) T. P. Rygiel et al.   JOURNAL OF CELL SCIENCE

Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia

(2008) L S Steelman et al.   LEUKEMIA

The Involvement of the Tyrosine Kinase c-Src in the Regulation of Reactive Oxygen Species Generation Mediated by NADPH Oxidase-1

(2008) Davide Gianni et al.   MOLECULAR BIOLOGY OF THE CELL

Salvicine Inactivates  1 Integrin and Inhibits Adhesion of MDA-MB-435 Cells to Fibronectin via Reactive Oxygen Species Signaling

(2008) J. Zhou et al.   MOLECULAR CANCER RESEARCH

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL

Sodium arsenite induces ROS generation, DNA oxidative damage, HO-1 and c-Myc proteins, NF-κB activation and cell proliferation in human breast cancer MCF-7 cells

(2008) Ruben Ruiz-Ramos et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c

(2008) Allyson E. Vaughn et al.   NATURE CELL BIOLOGY

2-Deoxy-d-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer

(2007) Mitchell C. Coleman et al.   FREE RADICAL BIOLOGY AND MEDICINE

2-Deoxyglucose combined with wild-type p53 overexpression enhances cytotoxicity in human prostate cancer cells via oxidative stress

(2007) Iman M. Ahmad et al.   FREE RADICAL BIOLOGY AND MEDICINE

EGCG inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer

(2007) Sharmila Shankar   Frontiers in Bioscience-Landmark