Glycosylation in health and disease

Structure and Immune Recognition of the HIV Glycan Shield

(2018) Max Crispin et al.   Annual Review of Biophysics

Engineered Sialylation of Pathogenic Antibodies In Vivo Attenuates Autoimmune Disease

(2018) Jose D. Pagan et al.   CELL

The Neutralizing Antibody Response to the HIV-1 Env Protein

(2018) Penny L. Moore   CURRENT HIV RESEARCH

O-Glycosylation–mediated signaling circuit drives metastatic castration-resistant prostate cancer

(2018) Sheue-Fen Tzeng et al.   FASEB JOURNAL

Crosstalk between phosphorylation and O-GlcNAcylation: friend or foe

(2018) Saar A. M. van der Laarse et al.   FEBS Journal

Glycosylation of Immunoglobulin G Associates With Clinical Features of Inflammatory Bowel Diseases

(2018) Mirna Šimurina et al.   GASTROENTEROLOGY

Transcriptome and functional analysis in a Drosophila model of NGLY1 deficiency provides insight into therapeutic approaches

(2018) Katie G Owings et al.   HUMAN MOLECULAR GENETICS

HIV-1 Vaccines Based on Antibody Identification, B Cell Ontogeny, and Epitope Structure

(2018) Peter D. Kwong et al.   IMMUNITY

O-GlcNAcylation of cardiac Nav1.5 contributes to the development of arrhythmias in diabetic hearts

(2018) Peng Yu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

CDG Therapies: From Bench to Bedside

(2018) Sandra Brasil et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glycosylation as a Main Regulator of Growth and Death Factor Receptors Signaling

(2018) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Galectins as Molecular Targets for Therapeutic Intervention

(2018) Ruud Dings et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Galectins at a glance

(2018) Ludger Johannes et al.   JOURNAL OF CELL SCIENCE

Dual TLR agonist nanodiscs as a strong adjuvant system for vaccines and immunotherapy

(2018) Rui Kuai et al.   JOURNAL OF CONTROLLED RELEASE

HIV-1 Envelope Glycoproteins from Diverse Clades Differentiate Antibody Responses and Durability among Vaccinees

(2018) Nicole L. Yates et al.   JOURNAL OF VIROLOGY

Mitochondrial function requires NGLY1

(2018) Jianping Kong et al.   MITOCHONDRION

Integrating biomarkers across omic platforms: an approach to improve stratification of patients with indolent and aggressive prostate cancer

(2018) Keefe Murphy et al.   Molecular Oncology

Glycan modifications to the gp120 immunogens used in the RV144 vaccine trial improve binding to broadly neutralizing antibodies

(2018) Rachel C. Doran et al.   PLoS One

Metabolic control of T cell immune response through glycans in inflammatory bowel disease

(2018) Ana M. Dias et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perspectives on Glycosylation and Its Congenital Disorders

(2018) Bobby G. Ng et al.   TRENDS IN GENETICS

The Glycoscience of Immunity

(2018) Julie Y. Zhou et al.   TRENDS IN IMMUNOLOGY

B4GALNT2 and xenotransplantation: A newly appreciated xenogeneic antigen

(2018) Guerard Byrne et al.   XENOTRANSPLANTATION

Sialylation of EGFR by the ST6Gal-I sialyltransferase promotes EGFR activation and resistance to gefitinib-mediated cell death

(2018) Colleen M. Britain et al.   Journal of Ovarian Research

CD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice

(2018) Naoko Matsubara et al.   Frontiers in Immunology

Sialylated Autoantigen-Reactive IgG Antibodies Attenuate Disease Development in Autoimmune Mouse Models of Lupus Nephritis and Rheumatoid Arthritis

(2018) Yannic C. Bartsch et al.   Frontiers in Immunology

Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns

(2018) Annika Wahl et al.   Frontiers in Immunology

The Nutrient-Sensing Hexosamine Biosynthetic Pathway as the Hub of Cancer Metabolic Rewiring

(2018) Ferdinando Chiaradonna et al.   Cells

IgA regulates the composition and metabolic function of gut microbiota by promoting symbiosis between bacteria

(2018) Akira Nakajima et al.   JOURNAL OF EXPERIMENTAL MEDICINE

N-Linked Glycan Branching and Fucosylation Are Increased Directly in Hcc Tissue As Determined through in Situ Glycan Imaging

(2018) Connor A. West et al.   JOURNAL OF PROTEOME RESEARCH

Loss of GCNT2/I-branched glycans enhances melanoma growth and survival

(2018) Jenna Geddes Sweeney et al.   Nature Communications

Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycans

(2018) N. Giovannone et al.   Nature Communications

CD22: A Regulator of Innate and Adaptive B Cell Responses and Autoimmunity

(2018) Edward A. Clark et al.   Frontiers in Immunology

Long-term follow-up in PMM2-CDG: are we ready to start treatment trials?

(2018) Peter Witters et al.   GENETICS IN MEDICINE

Congenital disorders of glycosylation (CDG): Quo vadis?

(2017) Romain Péanne et al.   European Journal of Medical Genetics

Bacterial phosphoglycosyl transferases: initiators of glycan biosynthesis at the membrane interface

(2017) Vinita Lukose et al.   GLYCOBIOLOGY

Viewing Siglecs through the lens of tumor immunology

(2017) Isabella Fraschilla et al.   IMMUNOLOGICAL REVIEWS

The HIV-1 envelope glycoprotein structure: nailing down a moving target

(2017) Andrew B Ward et al.   IMMUNOLOGICAL REVIEWS

Sweet SIGNs: IgG glycosylation leads the way in IVIG-mediated resolution of inflammation

(2017) Christin Brückner et al.   INTERNATIONAL IMMUNOLOGY

Galectin-1 Inhibitor OTX008 Induces Tumor Vessel Normalization and Tumor Growth Inhibition in Human Head and Neck Squamous Cell Carcinoma Models

(2017) Nathan Koonce et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ST6Gal-I sialyltransferase promotes chemoresistance in pancreatic ductal adenocarcinoma by abrogating gemcitabine-mediated DNA damage

(2017) Asmi Chakraborty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Engineering the fragment crystallizable (Fc) region of human IgG1 multimers and monomers to fine-tune interactions with sialic acid-dependent receptors

(2017) Patricia A. Blundell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extrinsic sialylation is dynamically regulated by systemic triggersin vivo

(2017) Charles T. Manhardt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyposialylated IgG activates endothelial IgG receptor FcγRIIB to promote obesity-induced insulin resistance

(2017) Keiji Tanigaki et al.   JOURNAL OF CLINICAL INVESTIGATION

T cells control the generation of nanomolar-affinity anti-glycan antibodies

(2017) Zinaida Polonskaya et al.   JOURNAL OF CLINICAL INVESTIGATION

Galactosylation of IgA1 Is Associated with Common Variation in C1GALT1

(2017) Daniel P. Gale et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Glomerular basement membrane heparan sulfate in health and disease: A regulator of local complement activation

(2017) Dorin-Bogdan Borza   MATRIX BIOLOGY

Phenotypic and genotypic spectrum of congenital disorders of glycosylation type I and type II

(2017) Amal Al Teneiji et al.   MOLECULAR GENETICS AND METABOLISM

Heparanase: roles in cell survival, extracellular matrix remodelling and the development of kidney disease

(2017) Ton J. Rabelink et al.   Nature Reviews Nephrology

Role of protein glycosylation in cancer metastasis

(2017) Leticia Oliveira-Ferrer et al.   SEMINARS IN CANCER BIOLOGY

Molecular basis of human CD22 function and therapeutic targeting

(2017) June Ereño-Orbea et al.   Nature Communications

Particle-based delivery of the HIV envelope protein

(2017) Benedikt Asbach et al.   Current Opinion in HIV and AIDS

Stabilized HIV-1 envelope glycoprotein trimers for vaccine use

(2017) Max Medina-Ramírez et al.   Current Opinion in HIV and AIDS

Nutritional Therapies in Congenital Disorders of Glycosylation (CDG)

(2017) Peter Witters et al.   Nutrients

Native glycan fragments detected by MALDI-FT-ICR mass spectrometry imaging impact gastric cancer biology and patient outcome

(2017) Thomas Kunzke et al.   Oncotarget

GWAS for serum galactose-deficient IgA1 implicates critical genes of the O-glycosylation pathway

(2017) Krzysztof Kiryluk et al.   PLoS Genetics

Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1

(2017) Jason E. Hammonds et al.   PLoS Pathogens

Tissue-specific regulation of BMP signaling by Drosophila N-glycanase 1

(2017) Antonio Galeone et al.   eLife

Enzymatic insights into an inherited genetic disorder

(2017) Liping Zhang et al.   eLife

Host Immune Responses in HIV-1 Infection: The Emerging Pathogenic Role of Siglecs and Their Clinical Correlates

(2017) Joanna Mikulak et al.   Frontiers in Immunology

Fc-Galactosylation of Human Immunoglobulin Gamma Isotypes Improves C1q Binding and Enhances Complement-Dependent Cytotoxicity

(2017) Benjamin Peschke et al.   Frontiers in Immunology

Crystallizable Fragment Glycoengineering for Therapeutic Antibodies Development

(2017) Wei Li et al.   Frontiers in Immunology

Galactosylation and Sialylation Levels of IgG Predict Relapse in Patients With PR3-ANCA Associated Vasculitis

(2017) Michael J. Kemna et al.   EBioMedicine

Anti-Neu5Gc and anti-non-Neu5Gc antibodies in healthy humans

(2017) Bingsi Gao et al.   PLoS One

Hyperglycemia-related advanced glycation end-products is associated with the altered phosphatidylcholine metabolism in osteoarthritis patients with diabetes

(2017) Weidong Zhang et al.   PLoS One

Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health

(2017) Rosina Plomp et al.   Scientific Reports

Galectins and Immune Responses—Just How Do They Do Those Things They Do?

(2016) Sandra Thiemann et al.   Annual Review of Immunology

Histo-blood group glycans in the context of personalized medicine

(2016) Viktoria Dotz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Glyco-genes change expression in cancer through aberrant methylation

(2016) Aleksandar Vojta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Loss of N-acetylgalactosaminyltransferase 3 in poorly differentiated pancreatic cancer: augmented aggressiveness and aberrant ErbB family glycosylation

(2016) Seema Chugh et al.   BRITISH JOURNAL OF CANCER

Metastatic Progression of Prostate Cancer Is Mediated by Autonomous Binding of Galectin-4- O -Glycan to Cancer Cells

(2016) Chin-Hsien Tsai et al.   CANCER RESEARCH

The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype

(2016) Matthew J. Schultz et al.   CANCER RESEARCH

Circulating blood and platelets supply glycosyltransferases that enable extrinsic extracellular glycosylation

(2016) Melissa M Lee-Sundlov et al.   GLYCOBIOLOGY

Biological roles of glycans

(2016) Ajit Varki   GLYCOBIOLOGY

Pharmacological Chaperoning: A Potential Treatment for PMM2-CDG

(2016) Patricia Yuste-Checa et al.   HUMAN MUTATION

Engagement of distinct epitopes on CD43 induces different co-stimulatory pathways in human T cells

(2016) Madhura Modak et al.   IMMUNOLOGY

Training the next generation of biomedical investigators in glycosciences

(2016) Peter Agre et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunological aspects of congenital disorders of glycosylation (CDG): a review

(2016) Maria Monticelli et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Glycobiology simplified: diverse roles of glycan recognition in inflammation

(2016) Ronald L. Schnaar   JOURNAL OF LEUKOCYTE BIOLOGY

Changes in Healthy Human IgG Fc-Glycosylation after Birth and during Early Childhood

(2016) Noortje de Haan et al.   JOURNAL OF PROTEOME RESEARCH

Sweet but dangerous – the role of immunoglobulin G glycosylation in autoimmunity and inflammation

(2016) M H C Biermann et al.   LUPUS

Molecular Basis of Assembly and Activation of Complement Component C1 in Complex with Immunoglobulin G1 and Antigen

(2016) Guanbo Wang et al.   MOLECULAR CELL

Epithelial glycosylation in gut homeostasis and inflammation

(2016) Yoshiyuki Goto et al.   NATURE IMMUNOLOGY

Regulation of autoantibody activity by the IL-23–TH17 axis determines the onset of autoimmune disease

(2016) René Pfeifle et al.   NATURE IMMUNOLOGY

Structural basis for norovirus neutralization by an HBGA blocking human IgA antibody

(2016) Sreejesh Shanker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Siglec-1 and -2 as potential biomarkers in autoimmune disease

(2016) Amanda J. Eakin et al.   Proteomics Clinical Applications

Sialylation converts arthritogenic IgG into inhibitors of collagen-induced arthritis

(2016) Yuhsuke Ohmi et al.   Nature Communications

Effects of the P‐Selectin Antagonist Inclacumab on Myocardial Damage After Percutaneous Coronary Intervention According to Timing of Infusion: Insights From the SELECT‐ACS Trial

(2016) Barbara E. Stähli et al.   Journal of the American Heart Association

Tn-MUC1 DC Vaccination of Rhesus Macaques and a Phase I/II Trial in Patients with Nonmetastatic Castrate-Resistant Prostate Cancer

(2016) E. Scheid et al.   Cancer Immunology Research

N-glycosylation proteome enrichment analysis in kidney reveals differences between diabetic mouse models

(2016) Leena Liljedahl et al.   Clinical Proteomics

The Origin and Activities of IgA1-Containing Immune Complexes in IgA Nephropathy

(2016) Barbora Knoppova et al.   Frontiers in Immunology

IgA nephropathy

(2016) Kar Neng Lai et al.   Nature Reviews Disease Primers

IgG1 Fc N-glycan galactosylation as a biomarker for immune activation

(2016) Sanne E. de Jong et al.   Scientific Reports

Neurological Aspects of Human Glycosylation Disorders

(2015) Hudson H. Freeze et al.   Annual Review of Neuroscience

Blood Groups in Infection and Host Susceptibility

(2015) Laura Cooling   CLINICAL MICROBIOLOGY REVIEWS

Symbol Nomenclature for Graphical Representations of Glycans

(2015) Ajit Varki et al.   GLYCOBIOLOGY

Rabbit antithymocyte globulin–induced serum sickness disease and human kidney graft survival

(2015) Grégoire Couvrat-Desvergnes et al.   JOURNAL OF CLINICAL INVESTIGATION

Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity

(2015) Isaak Quast et al.   JOURNAL OF CLINICAL INVESTIGATION

Skewed Fc Glycosylation Profiles of Anti-proteinase 3 Immunoglobulin G1 Autoantibodies from Granulomatosis with Polyangiitis Patients Show Low Levels of Bisection, Galactosylation, and Sialylation

(2015) Manfred Wuhrer et al.   JOURNAL OF PROTEOME RESEARCH

Proteoglycan form and function: A comprehensive nomenclature of proteoglycans

(2015) Renato V. Iozzo et al.   MATRIX BIOLOGY

An extracatalytic function of CD45 in B cells is mediated by CD22

(2015) Sarah Coughlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A common glycan structure on immunoglobulin G for enhancement of effector functions

(2015) Chin-Wei Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection

(2015) X. Sewald et al.   SCIENCE

Congenital disorders of glycosylation: a concise chart of glycocalyx dysfunction

(2015) Thierry Hennet et al.   TRENDS IN BIOCHEMICAL SCIENCES

Evaluation of human and non-human primate antibody binding to pig cells lacking GGTA1/CMAH/β4GalNT2 genes

(2015) Jose L. Estrada et al.   XENOTRANSPLANTATION

Intestinal CD169+ macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes

(2015) Kenichi Asano et al.   Nature Communications

The need for xenotransplantation as a source of organs and cells for clinical transplantation

(2015) Burcin Ekser et al.   International Journal of Surgery

Association of Systemic Lupus Erythematosus With Decreased Immunosuppressive Potential of the IgG Glycome

(2015) Frano Vučković et al.   Arthritis & Rheumatology

The HIV-1 gp120 V1V2 loop: structure, function and importance for vaccine development

(2014) Robert J O’Connell et al.   Expert Review of Vaccines

Mutations in NGLY1 cause an inherited disorder of the endoplasmic reticulum–associated degradation pathway

(2014) Gregory M. Enns et al.   GENETICS IN MEDICINE

A glycogene mutation map for discovery of diseases of glycosylation

(2014) Lars Hansen et al.   GLYCOBIOLOGY

Novel roles for O-linked glycans in protein folding

(2014) Deepika Vasudevan et al.   GLYCOCONJUGATE JOURNAL

Diagnosis and classification of rheumatoid arthritis

(2014) Maria Kourilovitch et al.   JOURNAL OF AUTOIMMUNITY

Platelets Support Extracellular Sialylation by Supplying the Sugar Donor Substrate

(2014) Melissa M. Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytokines Alter IgA1O-Glycosylation by Dysregulating C1GalT1 and ST6GalNAc-II Enzymes

(2014) Hitoshi Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Prevalence of Diabetic Cardiomyopathy: A Population-Based Study in Olmsted County, Minnesota

(2014) Sanjay Dandamudi et al.   JOURNAL OF CARDIAC FAILURE

The role of glycosylation in IBD

(2014) Evropi Theodoratou et al.   Nature Reviews Gastroenterology & Hepatology

Glycosylation, Hypogammaglobulinemia, and Resistance to Viral Infections

(2014) Mohammed A. Sadat et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase 1 Study of the E-Selectin Inhibitor GMI 1070 in Patients with Sickle Cell Anemia

(2014) Ted Wun et al.   PLoS One

Differential glycosylation of envelope gp120 is associated with differential recognition of HIV-1 by virus-specific antibodies and cell infection

(2014) Milan Raska et al.   AIDS Research and Therapy

Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis

(2013) Yoann Rombouts et al.   ANNALS OF THE RHEUMATIC DISEASES

Increasing the α 2, 6 Sialylation of Glycoproteins May Contribute to Metastatic Spread and Therapeutic Resistance in Colorectal Cancer

(2013) Jung-Jin Park et al.   Gut and Liver

Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling

(2013) Jinah Park et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Modification of Sialylation Mediates the Invasive Properties and Chemosensitivity of Human Hepatocellular Carcinoma

(2013) Yongfu Zhao et al.   MOLECULAR & CELLULAR PROTEOMICS

Adaptive immune activation: glycosylation does matter

(2013) Margreet A Wolfert et al.   Nature Chemical Biology

The podocyte slit diaphragm—from a thin grey line to a complex signalling hub

(2013) Florian Grahammer et al.   Nature Reviews Nephrology

Double knockout pigs deficient in N-glycolylneuraminic acid and Galactose α-1,3-Galactose reduce the humoral barrier to xenotransplantation

(2013) Andrew J. Lutz et al.   XENOTRANSPLANTATION

ST6Gal-I sialyltransferase confers cisplatin resistance in ovarian tumor cells

(2013) Matthew J Schultz et al.   Journal of Ovarian Research

Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers

(2013) Gordan Lauc et al.   PLoS Genetics

Heterogenic Endothelial Responses to Inflammation: Role for Differential N ‐Glycosylation and Vascular Bed of Origin

(2013) David W. Scott et al.   Journal of the American Heart Association

T cells modulate glycans on CD43 and CD45 during development and activation, signal regulation, and survival

(2012) Mary C. Clark et al.   Annals of the New York Academy of Sciences

The origin and function of platelet glycosyltransferases

(2012) H. H. Wandall et al.   BLOOD

Regulation of Glycan Structures in Murine Embryonic Stem Cells

(2012) Alison V. Nairn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mucin Function in Inflammatory Bowel Disease

(2012) Doron Boltin et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Defucosylated Anti-CCR4 Monoclonal Antibody (KW-0761) for Relapsed Adult T-Cell Leukemia-Lymphoma: A Multicenter Phase II Study

(2012) Takashi Ishida et al.   JOURNAL OF CLINICAL ONCOLOGY

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Fifteen years of research on nephrin: what we still need to know

(2012) Min Li et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

New Insights Into Human Minimal Change Disease: Lessons From Animal Models

(2011) Sumant S. Chugh et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Sialylation levels of anti-proteinase 3 antibodies are associated with the activity of granulomatosis with polyangiitis (Wegener's)

(2011) Cécile Espy et al.   ARTHRITIS AND RHEUMATISM

Isolation and characterization of IgG1 with asymmetrical Fc glycosylation

(2011) S. Ha et al.   GLYCOBIOLOGY

Control of mucin-type O-glycosylation: A classification of the polypeptide GalNAc-transferase gene family

(2011) E. P. Bennett et al.   GLYCOBIOLOGY

Endothelial SurfaceN-Glycans Mediate Monocyte Adhesion and Are Targets for Anti-inflammatory Effects of Peroxisome Proliferator-activated Receptor γ Ligands

(2011) Balu K. Chacko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intravenous gammaglobulin suppresses inflammation through a novel TH2 pathway

(2011) Robert M. Anthony et al.   NATURE

Aberrant IgG galactosylation precedes disease onset, correlates with disease activity, and is prevalent in autoantibodies in rheumatoid arthritis

(2010) Altan Ercan et al.   ARTHRITIS AND RHEUMATISM

Translational Pharmacokinetics and Pharmacodynamics of an FcRn-Variant Anti-CD4 Monoclonal Antibody From Preclinical Model to Phase I Study

(2010) Y Zheng et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The glomerulus – a view from the inside – the endothelial cell

(2010) Agnes B. Fogo et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Regulation ofO-glycosylation through Golgi-to-ER relocation of initiation enzymes

(2010) David J. Gill et al.   JOURNAL OF CELL BIOLOGY

A Novel Role for the IgG Fc Glycan: The Anti-inflammatory Activity of Sialylated IgG Fcs

(2010) Robert M. Anthony et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Phase I Study of KW-0761, a Defucosylated Humanized Anti-CCR4 Antibody, in Relapsed Patients With Adult T-Cell Leukemia-Lymphoma and Peripheral T-Cell Lymphoma

(2010) Kazuhito Yamamoto et al.   JOURNAL OF CLINICAL ONCOLOGY

Pharmacokinetics and Antibody Responses to the CD3 Antibody Otelixizumab Used in the Treatment of Type 1 Diabetes

(2010) Geoff Hale et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome

(2010) Lionel C Clement et al.   NATURE MEDICINE

Nineteen novel NPHS1 mutations in a worldwide cohort of patients with congenital nephrotic syndrome (CNS)

(2010) Dominik S. Schoeb et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Identification of New Carbohydrate and Membrane Protein Antigens in Cardiac Xenotransplantation

(2010) Guerard W. Byrne et al.   TRANSPLANTATION

Location, location, location: new insights into O-GalNAc protein glycosylation

(2010) David J. Gill et al.   TRENDS IN CELL BIOLOGY

Anti-angiogenesis and anti-tumor effects of AdNT4-anginex

(2009) Dan Feng Dong et al.   CANCER LETTERS

Modulation of immune cell signalling by the leukocyte common tyrosine phosphatase, CD45

(2009) A.E. Saunders et al.   CELLULAR SIGNALLING

Dystroglycan in the Molecular Diagnosis of the Podocytopathies

(2009) J. B. Kopp   Clinical Journal of the American Society of Nephrology

N- andO-Glycans Modulate Galectin-1 Binding, CD45 Signaling, and T Cell Death

(2009) Lesley A. Earl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycosylation as a strategy to improve antibody-based therapeutics

(2009) Roy Jefferis   NATURE REVIEWS DRUG DISCOVERY

Key developmental transitions in human germinal center B cells are revealed by differential CD45RB expression

(2008) S. M. Jackson et al.   BLOOD

O-GlcNAc modulation at Akt1 Ser473 correlates with apoptosis of murine pancreatic β cells

(2008) Eun-Sil Kang et al.   EXPERIMENTAL CELL RESEARCH

The N-linked oligosaccharide at Fc RIIIa Asn-45: an inhibitory element for high Fc RIIIa binding affinity to IgG glycoforms lacking core fucosylation

(2008) M. Shibata-Koyama et al.   GLYCOBIOLOGY

Novel functions of the CD34 family

(2008) J. S. Nielsen et al.   JOURNAL OF CELL SCIENCE

Properties of the Glomerular Barrier and Mechanisms of Proteinuria

(2008) Börje Haraldsson et al.   PHYSIOLOGICAL REVIEWS

Aglycosylated immunoglobulin G1 variants productively engage activating Fc receptors

(2008) S. L. Sazinsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA