Molecular basis of human CD22 function and therapeutic targeting

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

Initiation of T cell signaling by CD45 segregation at 'close contacts'

(2016) Veronica T Chang et al.   NATURE IMMUNOLOGY

Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-8

(2016) Johannes M. Pröpster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Higher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain

(2016) Tristan I. Croll et al.   STRUCTURE

Structural basis of myelin-associated glycoprotein adhesion and signalling

(2016) Matti F. Pronker et al.   Nature Communications

The mechanistic impact of CD22 engagement with epratuzumab on B cell function: Implications for the treatment of systemic lupus erythematosus

(2015) Thomas Dörner et al.   AUTOIMMUNITY REVIEWS

An extracatalytic function of CD45 in B cells is mediated by CD22

(2015) Sarah Coughlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ambiguity assessment of small-angle scattering curves from monodisperse systems

(2015) Maxim V. Petoukhov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Disubstituted sialic acid ligands targeting siglecs CD33 and CD22 associated with myeloid leukaemias and B cell lymphomas

(2014) Cory D. Rillahan et al.   Chemical Science

Ten years of probabilistic estimates of biocrystal solvent content: new insightsvianonparametric kernel density estimate

(2014) Christian X. Weichenberger et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Targeting CD22 in B-cell Malignancies: Current Status and Clinical Outlook

(2013) Loretta Sullivan-Chang et al.   BIODRUGS

Trogocytosis of multiple B-cell surface markers by CD22 targeting with epratuzumab

(2013) E. A. Rossi et al.   BLOOD

Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis

(2013) Matthew S. Macauley et al.   JOURNAL OF CLINICAL INVESTIGATION

DropArray™, a Wall-Less 96-Well Plate for Uptake and Immunofluorescence Microscopy, Confirms CD22 Recycles

(2013) Gladys S. Ingle et al.   TRAFFIC

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

Siglecs and Immune Regulation

(2012) Shiv Pillai et al.   Annual Review of Immunology

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Regulation of B Cell Functions by the Sialic Acid-Binding Receptors Siglec-G and CD22

(2012) Julia Jellusova et al.   Frontiers in Immunology

From a Library of MAG Antagonists to Nanomolar CD22 Ligands

(2011) Stefanie Mesch et al.   ChemMedChem

Antibody Fusion Proteins: Anti-CD22 Recombinant Immunotoxin Moxetumomab Pasudotox

(2011) R. J. Kreitman et al.   CLINICAL CANCER RESEARCH

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

CD22 Is a Recycling Receptor That Can Shuttle Cargo between the Cell Surface and Endosomal Compartments of B Cells

(2010) M. K. O'Reilly et al.   JOURNAL OF IMMUNOLOGY

Structural and Functional Studies of Igαβ and Its Assembly with the B Cell Antigen Receptor

(2010) Sergei Radaev et al.   STRUCTURE

CD22: an inhibitory enigma

(2008) Jennifer A. Walker et al.   IMMUNOLOGY

B cell antigen receptor signal strength and peripheral B cell development are regulated by a 9-O-acetyl sialic acid esterase

(2008) Annaiah Cariappa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Structural Implications of Siglec-5-Mediated Sialoglycan Recognition

(2007) Marina A. Zhuravleva et al.   JOURNAL OF MOLECULAR BIOLOGY