Epithelial glycosylation in gut homeostasis and inflammation

CRISPR/Cas9 Screens Reveal Requirements for Host Cell Sulfation and Fucosylation in Bacterial Type III Secretion System-Mediated Cytotoxicity

(2016) Carlos J. Blondel et al.   Cell Host & Microbe

Association of elevated rotavirus-specific antibody titers with HBGA secretor status in Swedish individuals: The FUT2 gene as a putative susceptibility determinant for infection

(2016) Gökçe Günaydın et al.   VIRUS RESEARCH

Microbiota-Mediated Inflammation and Antimicrobial Defense in the Intestine

(2015) Silvia Caballero et al.   Annual Review of Immunology

Plasma membrane reorganization: A glycolipid gateway for microbes

(2015) Sahaja Aigal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

An IL-23R/IL-22 Circuit Regulates Epithelial Serum Amyloid A to Promote Local Effector Th17 Responses

(2015) Teruyuki Sano et al.   CELL

Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells

(2015) Koji Atarashi et al.   CELL

Genetic susceptibility factors for alcohol-induced chronic pancreatitis

(2015) Ali A. Aghdassi et al.   PANCREATOLOGY

IL-10-producing CD4+ T cells negatively regulate fucosylation of epithelial cells in the gut

(2015) Yoshiyuki Goto et al.   Scientific Reports

Epidemiologic Association BetweenFUT2Secretor Status and Severe Rotavirus Gastroenteritis in Children in the United States

(2015) Daniel C. Payne et al.   JAMA Pediatrics

Maternal fucosyltransferase 2 status affects the gut bifidobacterial communities of breastfed infants

(2015) Zachery T Lewis et al.   Microbiome

Epithelial IL-22RA1-Mediated Fucosylation Promotes Intestinal Colonization Resistance to an Opportunistic Pathogen

(2014) Tu Anh N. Pham et al.   Cell Host & Microbe

Reprograming of gut microbiome energy metabolism by the FUT2 Crohn’s disease risk polymorphism

(2014) Maomeng Tong et al.   ISME Journal

Rapid fucosylation of intestinal epithelium sustains host–commensal symbiosis in sickness

(2014) Joseph M. Pickard et al.   NATURE

Innate lymphoid cells regulate intestinal epithelial cell glycosylation

(2014) Y. Goto et al.   SCIENCE

Loss of NHE3 alters gut microbiota composition and influences Bacteroides thetaiotaomicron growth

(2013) Melinda A. Engevik et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

FUT2: filling the gap between genes and environment in Behçet's disease?

(2013) Joana M Xavier et al.   ANNALS OF THE RHEUMATIC DISEASES

Synthesis of Fucosyl-N-Acetylglucosamine Disaccharides by Transfucosylation Using α-l-Fucosidases from Lactobacillus casei

(2013) Jesús Rodríguez-Díaz et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Mucosal innate immune cells regulate both gut homeostasis and intestinal inflammation

(2013) Yosuke Kurashima et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Glucocorticoids and microbiota regulate ontogeny of intestinal fucosyltransferase 2 requisite for gut homeostasis

(2013) N. N. Nanthakumar et al.   GLYCOBIOLOGY

Intestinal epithelial cells as mediators of the commensal-host immune crosstalk

(2013) Yoshiyuki Goto et al.   IMMUNOLOGY AND CELL BIOLOGY

A FUT2 Gene Common Polymorphism Determines Resistance to Rotavirus A of the P[8] Genotype

(2013) Berthe-Marie Imbert-Marcille et al.   JOURNAL OF INFECTIOUS DISEASES

The Human Milk Metabolome Reveals Diverse Oligosaccharide Profiles

(2013) Jennifer T. Smilowitz et al.   JOURNAL OF NUTRITION

A large-scale screen for coding variants predisposing to psoriasis

(2013) Huayang Tang et al.   NATURE GENETICS

Genetically dictated change in host mucus carbohydrate landscape exerts a diet-dependent effect on the gut microbiota

(2013) P. C. Kashyap et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Microbiome in Infectious Disease and Inflammation

(2012) Kenya Honda et al.   Annual Review of Immunology

Interleukin 23 Production by Intestinal CD103+CD11b+ Dendritic Cells in Response to Bacterial Flagellin Enhances Mucosal Innate Immune Defense

(2012) Melissa A. Kinnebrew et al.   IMMUNITY

Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci

(2012) Trine Folseraas et al.   JOURNAL OF HEPATOLOGY

Fucose sensing regulates bacterial intestinal colonization

(2012) Alline R. Pacheco et al.   NATURE

The role of receptor binding specificity in interspecies transmission of influenza viruses

(2012) Masaki Imai et al.   Current Opinion in Virology

Lymphotoxin Controls the IL-22 Protection Pathway in Gut Innate Lymphoid Cells during Mucosal Pathogen Challenge

(2011) Alexei V. Tumanov et al.   Cell Host & Microbe

FUT2 Nonsecretor Status Links Type 1 Diabetes Susceptibility and Resistance to Infection: TABLE 1

(2011) Deborah J. Smyth et al.   DIABETES

Sweet-talk: role of host glycosylation in bacterial pathogenesis of the gastrointestinal tract

(2011) A. P. Moran et al.   GUT

Epithelial barrier: an interface for the cross-communication between gut flora and immune system

(2011) Yoshiyuki Goto et al.   IMMUNOLOGICAL REVIEWS

Ectopic expression of blood type antigens in inflamed mucosa with higher incidence of FUT2 secretor status in colonic Crohn’s disease

(2011) Jun Miyoshi et al.   JOURNAL OF GASTROENTEROLOGY

IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium

(2011) Naruhisa Ota et al.   NATURE IMMUNOLOGY

RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota

(2011) Shinichiro Sawa et al.   NATURE IMMUNOLOGY

Secretor Genotype (FUT2 gene) Is Strongly Associated with the Composition of Bifidobacteria in the Human Intestine

(2011) Pirjo Wacklin et al.   PLoS One

Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype

(2011) P. Rausch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Antibacterial Lectin RegIII  Promotes the Spatial Segregation of Microbiota and Host in the Intestine

(2011) S. Vaishnava et al.   SCIENCE

Epithelial Barriers in Homeostasis and Disease

(2010) Amanda M. Marchiando et al.   Annual Review of Pathology-Mechanisms of Disease

Distinct fucosylation of M cells and epithelial cells by Fut1 and Fut2, respectively, in response to intestinal environmental stress

(2010) Kazutaka Terahara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Helicobacter pylori adhesion to gastric epithelial cells is mediated by glycan receptors

(2010) A. Magalhães et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

(2010) Dermot P.B. McGovern et al.   HUMAN MOLECULAR GENETICS

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Fut2-null mice display an altered glycosylation profile and impaired BabA-mediated Helicobacter pylori adhesion to gastric mucosa

(2009) Ana Magalhães et al.   GLYCOBIOLOGY

Mucosal gene expression profiles following the colonization of immunocompetent defined-flora C3H mice with Helicobacter bilis: a prelude to typhlocolitis

(2009) Zhiping Liu et al.   MICROBES AND INFECTION

Uptake through glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response

(2009) Koji Hase et al.   NATURE

Do symbiotic bacteria subvert host immunity?

(2009) Lora V. Hooper   NATURE REVIEWS MICROBIOLOGY

Infection byHelicobacter pyloriexpressing the BabA adhesin is influenced by the secretor phenotype

(2008) M Azevedo et al.   JOURNAL OF PATHOLOGY

RosE represses Std fimbrial expression in Salmonella enterica serotype Typhimurium

(2008) Daniela Chessa et al.   MOLECULAR MICROBIOLOGY

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

(2008) Yan Zheng et al.   NATURE MEDICINE

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA