Sialylation of EGFR by the ST6Gal-I sialyltransferase promotes EGFR activation and resistance to gefitinib-mediated cell death

ST6Gal-I sialyltransferase promotes chemoresistance in pancreatic ductal adenocarcinoma by abrogating gemcitabine-mediated DNA damage

(2017) Asmi Chakraborty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Glycosyltransferase ST6Gal-I Protects Tumor Cells against Serum Growth Factor Withdrawal by Enhancing Survival Signaling and Proliferative Potential

(2017) Colleen M. Britain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of N-glycosylation in EGFR ectodomain ligand binding

(2017) Maryam Azimzadeh Irani et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Kinomic profiling identifies focal adhesion kinase 1 as a therapeutic target in advanced clear cell renal cell carcinoma

(2017) Arindam P. Ghosh et al.   Oncotarget

The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype

(2016) Matthew J. Schultz et al.   CANCER RESEARCH

Elevation of β-galactoside α2,6-sialyltransferase 1 in a fructoseresponsive manner promotes pancreatic cancer metastasis

(2016) Chi-Che Hsieh et al.   Oncotarget

Metabolic flux-driven sialylation alters internalization, recycling, and drug sensitivity of the epidermal growth factor receptor (EGFR) in SW1990 pancreatic cancer cells

(2016) Mohit P. Mathew et al.   Oncotarget

Generation of Microtumors Using 3D Human Biogel Culture System and Patient-derived Glioblastoma Cells for Kinomic Profiling and Drug Response Testing

(2016) Ashley N. Gilbert et al.   Jove-Journal of Visualized Experiments

N-Glycosylation as determinant of epidermal growth factor receptor conformation in membranes

(2015) Karol Kaszuba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of sialylation on EGFR phosphorylation and resistance to tyrosine kinase inhibition

(2015) Hsin-Yung Yen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glycosyltransferase ST6GAL1 contributes to the regulation of pluripotency in human pluripotent stem cells

(2015) Yu-Chieh Wang et al.   Scientific Reports

Targeting RTK Signaling Pathways in Cancer

(2015) Tarik Regad   Cancers

High Throughput Kinomic Profiling of Human Clear Cell Renal Cell Carcinoma Identifies Kinase Activity Dependent Molecular Subtypes

(2015) Joshua C. Anderson et al.   PLoS One

ST6Gal-I Protein Expression Is Upregulated in Human Epithelial Tumors and Correlates with Stem Cell Markers in Normal Tissues and Colon Cancer Cell Lines

(2013) A. F. Swindall et al.   CANCER RESEARCH

Kinase Control of Latent HIV-1 Infection: PIM-1 Kinase as a Major Contributor to HIV-1 Reactivation

(2013) A. Duverger et al.   JOURNAL OF VIROLOGY

EGF receptor trafficking: consequences for signaling and cancer

(2013) Alejandra Tomas et al.   TRENDS IN CELL BIOLOGY

ST6Gal-I sialyltransferase confers cisplatin resistance in ovarian tumor cells

(2013) Matthew J Schultz et al.   Journal of Ovarian Research

Sialylation of epidermal growth factor receptor regulates receptor activity and chemosensitivity to gefitinib in colon cancer cells

(2012) Jung-Jin Park et al.   BIOCHEMICAL PHARMACOLOGY

Regulation of the metastatic cell phenotype by sialylated glycans

(2012) Matthew J. Schultz et al.   CANCER AND METASTASIS REVIEWS

The epidermal growth factor receptor as a therapeutic target in epithelial ovarian cancer

(2012) Ting Gui et al.   Cancer Epidemiology

Structural and Quantitative Evidence for Dynamic Glycome Shift on Production of Induced Pluripotent Stem Cells

(2012) Kayo Hasehira et al.   MOLECULAR & CELLULAR PROTEOMICS

Sialylation of the Fas Death Receptor by ST6Gal-I Provides Protection against Fas-mediated Apoptosis in Colon Carcinoma Cells

(2011) Amanda F. Swindall et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ST6Gal-I Regulates Macrophage Apoptosis via α2-6 Sialylation of the TNFR1 Death Receptor

(2011) Zhongyu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activation in lung cancer cells

(2011) Y.-C. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

α2,6-Sialic Acid on Platelet Endothelial Cell Adhesion Molecule (PECAM) Regulates Its Homophilic Interactions and Downstream Antiapoptotic Signaling

(2010) Shinobu Kitazume et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor cell migration and invasion are regulated by expression of variant integrin glycoforms

(2008) Faheem M. Shaikh et al.   EXPERIMENTAL CELL RESEARCH

Shedding of epidermal growth factor receptor is a regulated process that occurs with overexpression in malignant cells

(2008) Marianela Perez-Torres et al.   EXPERIMENTAL CELL RESEARCH

Sialylation of β1 Integrins Blocks Cell Adhesion to Galectin-3 and Protects Cells against Galectin-3-induced Apoptosis

(2008) Ya Zhuo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function

(2008) Daniel R Christie et al.   Journal of Ovarian Research