标题
Making sense of the ageing methylome
作者
关键词
-
出版物
NATURE REVIEWS GENETICS
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-05-03
DOI
10.1038/s41576-022-00477-6
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- DNA methylation aging and transcriptomic studies in horses
- (2022) Steve Horvath et al. Nature Communications
- A mammalian methylation array for profiling methylation levels at conserved sequences
- (2022) Adriana Arneson et al. Nature Communications
- Multi-omic rejuvenation of human cells by maturation phase transient reprogramming
- (2022) Diljeet Gill et al. eLife
- Aging and rejuvenation - a modular epigenome model
- (2021) Priscila Chiavellini et al. Aging-US
- DNA methylation predicts age and provides insight into exceptional longevity of bats
- (2021) Gerald S. Wilkinson et al. Nature Communications
- A Meta-Analysis of Brain DNA Methylation Across Sex, Age, and Alzheimer's Disease Points for Accelerated Epigenetic Aging in Neurodegeneration
- (2021) Camilla Pellegrini et al. Frontiers in Aging Neuroscience
- Novel DNA methylation signatures of tobacco smoking with trans-ethnic effects
- (2021) C. Christiansen et al. Clinical Epigenetics
- The central role of DNA damage in the ageing process
- (2021) Björn Schumacher et al. NATURE
- Importance of circadian timing for aging and longevity
- (2021) Victoria A. Acosta-Rodríguez et al. Nature Communications
- An integrative analysis of the age-associated multi-omic landscape across cancers
- (2021) Kasit Chatsirisupachai et al. Nature Communications
- Disentangling age-dependent DNA methylation: deterministic, stochastic, and nonlinear
- (2021) O. Vershinina et al. Scientific Reports
- DNA methylation biomarkers of myocardial infarction and cardiovascular disease
- (2021) Alba Fernández-Sanlés et al. Clinical Epigenetics
- DNA methylation and gene expression integration in cardiovascular disease
- (2021) Guillermo Palou-Márquez et al. Clinical Epigenetics
- Sex differences in biological aging with a focus on human studies
- (2021) Sara Hägg et al. eLife
- Epigenetic clock and methylation studies in elephants
- (2021) Natalia A. Prado et al. AGING CELL
- Cellular reprogramming and epigenetic rejuvenation
- (2021) Daniel J. Simpson et al. Clinical Epigenetics
- Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci
- (2021) Victoria J Sugrue et al. eLife
- Meta‐analysis of genome‐wide DNA methylation and integrative omics of age in human skeletal muscle
- (2021) Sarah Voisin et al. Journal of Cachexia Sarcopenia and Muscle
- Epigenetic clocks reveal a rejuvenation event during embryogenesis followed by aging
- (2021) Csaba Kerepesi et al. Science Advances
- Epigenetic clock and DNA methylation analysis of porcine models of aging and obesity
- (2021) Kyle M. Schachtschneider et al. GeroScience
- Epigenetic clock and methylation studies in the rhesus macaque
- (2021) Steve Horvath et al. GeroScience
- Epigenetic clock and methylation studies in cats
- (2021) Ken Raj et al. GeroScience
- DNA methylation age analysis of rapamycin in common marmosets
- (2021) Steve Horvath et al. GeroScience
- Multi-species and multi-tissue methylation clocks for age estimation in toothed whales and dolphins
- (2021) Todd R. Robeck et al. Communications Biology
- Rejuvant®, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the TruAge DNA methylation test
- (2021) Oleksandr Demidenko et al. Aging-US
- Physical exercise shapes the mouse brain epigenome
- (2021) Rocío G. Urdinguio et al. Molecular Metabolism
- Network analysis of human muscle adaptation to aging and contraction
- (2020) Craig Willis et al. Aging-US
- The ageing epigenome and its rejuvenation
- (2020) Weiqi Zhang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Associations between high blood pressure and DNA methylation
- (2020) Nabila Kazmi et al. PLoS One
- An epigenetic clock for human skeletal muscle
- (2020) Sarah Voisin et al. Journal of Cachexia Sarcopenia and Muscle
- Current perspectives on the cellular and molecular features of epigenetic ageing
- (2020) Kenneth Raj et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- NAD+ Controls Circadian Reprogramming through PER2 Nuclear Translocation to Counter Aging
- (2020) Daniel C. Levine et al. MOLECULAR CELL
- The quest to slow ageing through drug discovery
- (2020) Linda Partridge et al. NATURE REVIEWS DRUG DISCOVERY
- Promoter methylation changes in ALOX12 and AIRE1: novel epigenetic markers for atherosclerosis
- (2020) Jee Yeon Kim et al. Clinical Epigenetics
- DNA Methylation Biomarkers in Aging and Age-Related Diseases
- (2020) Yasmeen Salameh et al. Frontiers in Genetics
- Calorie Restriction and Aging in Humans
- (2020) Emily W. Flanagan et al. Annual Review of Nutrition
- A comparison of epigenetic mitotic-like clocks for cancer risk prediction
- (2020) Andrew E. Teschendorff Genome Medicine
- Epigenetic mutation load is weakly correlated with epigenetic age acceleration
- (2020) Qi Yan et al. Aging-US
- Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice
- (2020) Azar Asadi Shahmirzadi et al. Cell Metabolism
- The Ground Zero of Organismal Life and Aging
- (2020) Vadim N. Gladyshev TRENDS IN MOLECULAR MEDICINE
- DNA methylation across the genome in aged human skeletal muscle tissue and muscle-derived cells: the role of HOX genes and physical activity
- (2020) D. C. Turner et al. Scientific Reports
- Features of DNA Repair in the Early Stages of Mammalian Embryonic Development
- (2020) Evgenia V. Khokhlova et al. Genes
- Age-related DNA methylation changes are sex-specific: a comprehensive assessment
- (2020) Igor Yusipov et al. Aging-US
- Reprogramming to recover youthful epigenetic information and restore vision
- (2020) Yuancheng Lu et al. NATURE
- NAD+ metabolism and its roles in cellular processes during ageing
- (2020) Anthony J. Covarrubias et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer’s disease
- (2020) Lanyu Zhang et al. Nature Communications
- Aberrantly Methylated-Differentially Expressed Genes Identify Novel Atherosclerosis Risk Subtypes
- (2020) Yuzhou Xue et al. Frontiers in Genetics
- Crosstalk between metabolism and circadian clocks
- (2019) Hans Reinke et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Aberrant DNA methylation of M1-macrophage genes in coronary artery disease
- (2019) Chetan Bakshi et al. Scientific Reports
- Extracellular Spermine Activates DNA Methyltransferase 3A and 3B
- (2019) Taro Fukui et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Epigenetic changes during aging and their reprogramming potential
- (2019) Alice E. Kane et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Rapamycin retards epigenetic ageing of keratinocytes independently of its effects on replicative senescence, proliferation and differentiation
- (2019) Steve Horvath et al. Aging-US
- Spermine and gene methylation: a mechanism of lifespan extension induced by polyamine-rich diet
- (2019) Kuniyasu Soda AMINO ACIDS
- The Impact of Caloric Restriction on the Epigenetic Signatures of Aging
- (2019) Noémie Gensous et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms
- (2019) Peipei Li et al. Nature Communications
- Male mortality rates mirror mortality rates of older females
- (2019) Peter Lenart et al. Scientific Reports
- DNA methylation signature of human hippocampus in Alzheimer’s disease is linked to neurogenesis
- (2019) Miren Altuna et al. Clinical Epigenetics
- Reversal of epigenetic aging and immunosenescent trends in humans
- (2019) Gregory M. Fahy et al. AGING CELL
- Joint profiling of DNA methylation and chromatin architecture in single cells
- (2019) Guoqiang Li et al. NATURE METHODS
- The diverse roles of DNA methylation in mammalian development and disease
- (2019) Maxim V. C. Greenberg et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Epigenetic aging: more than just a clock when it comes to cancer
- (2019) Ming Yu et al. CANCER RESEARCH
- Clonal hematopoiesis in human aging and disease
- (2019) Siddhartha Jaiswal et al. SCIENCE
- Distinct chromatin signatures of DNA hypomethylation in aging and cancer
- (2018) Raúl F. Pérez et al. AGING CELL
- Global remodeling of the mouse DNA methylome during aging and in response to calorie restriction
- (2018) András Sziráki et al. AGING CELL
- An epigenetic biomarker of aging for lifespan and healthspan
- (2018) Morgan E. Levine et al. Aging-US
- Higher spermidine intake is linked to lower mortality: a prospective population-based study
- (2018) Stefan Kiechl et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Revisiting the genomic hypomethylation hypothesis of aging
- (2018) Archana Unnikrishnan et al. Annals of the New York Academy of Sciences
- Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetes
- (2018) Francisco Barajas-Olmos et al. BMC Medical Genetics
- Cell-type-specific disturbance of DNA methylation pattern: a chance to get more benefit from and to minimize cohorts for epigenome-wide association studies
- (2018) Mario Bauer INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- DNA methylation-based biomarkers and the epigenetic clock theory of ageing
- (2018) Steve Horvath et al. NATURE REVIEWS GENETICS
- Cellular and epigenetic drivers of stem cell ageing
- (2018) Maria Ermolaeva et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Caloric restriction mitigates age-associated hippocampal differential CG and non-CG methylation
- (2018) Niran Hadad et al. NEUROBIOLOGY OF AGING
- Spermidine in health and disease
- (2018) Frank Madeo et al. SCIENCE
- Diurnal transcriptome atlas of a primate across major neural and peripheral tissues
- (2018) Ludovic S. Mure et al. SCIENCE
- Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging
- (2018) Gabriel Oh et al. Nature Communications
- Implementing a method for studying longitudinal DNA methylation variability in association with age
- (2018) Yunzhang Wang et al. Epigenetics
- DNA Methylation Clocks in Aging: Categories, Causes, and Consequences
- (2018) Adam E. Field et al. MOLECULAR CELL
- Facing up to the global challenges of ageing
- (2018) Linda Partridge et al. NATURE
- The Plasma NAD+ Metabolome is Dysregulated in ‘normal’ Ageing
- (2018) James Clement et al. REJUVENATION RESEARCH
- A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine
- (2018) Marc D. Ruben et al. Science Translational Medicine
- Cell and tissue type independent age-associated DNA methylation changes are not rare but common
- (2018) Tianyu Zhu et al. Aging-US
- Atherosclerosis-associated differentially methylated regions can reflect the disease phenotype and are often at enhancers
- (2018) Michelle Lacey et al. ATHEROSCLEROSIS
- Implications of Epigenetic Drift in Colorectal Neoplasia
- (2018) Georg E. Luebeck et al. CANCER RESEARCH
- Polyamine Metabolism and Gene Methylation in Conjunction with One-Carbon Metabolism
- (2018) Kuniyasu Soda INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The role of DNA methylation in epigenetics of aging
- (2018) Archana Unnikrishnan et al. PHARMACOLOGY & THERAPEUTICS
- Rhythms of the Genome: Circadian Dynamics from Chromatin Topology, Tissue-Specific Gene Expression, to Behavior
- (2018) Jake Yeung et al. TRENDS IN GENETICS
- DNA methylation variability in Alzheimer's disease
- (2018) Zhiguang Huo et al. NEUROBIOLOGY OF AGING
- DNA methylation and exposure to ambient air pollution in two prospective cohorts
- (2017) Michelle Plusquin et al. ENVIRONMENT INTERNATIONAL
- Potential energy landscapes identify the information-theoretic nature of the epigenome
- (2017) Garrett Jenkinson et al. NATURE GENETICS
- Identification of methylation haplotype blocks aids in deconvolution of heterogeneous tissue samples and tumor tissue-of-origin mapping from plasma DNA
- (2017) Shicheng Guo et al. NATURE GENETICS
- Statistical and integrative system-level analysis of DNA methylation data
- (2017) Andrew E. Teschendorff et al. NATURE REVIEWS GENETICS
- Modeling complex patterns of differential DNA methylation that associate with gene expression changes
- (2017) Christopher E. Schlosberg et al. NUCLEIC ACIDS RESEARCH
- Contribution of epigenetic mechanisms to variation in cancer risk among tissues
- (2017) Michael Klutstein et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PARP1 orchestrates epigenetic events setting up chromatin domains
- (2017) Fabio Ciccarone et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Genetic architecture of epigenetic and neuronal ageing rates in human brain regions
- (2017) Ake T. Lu et al. Nature Communications
- Caloric restriction delays age-related methylation drift
- (2017) Shinji Maegawa et al. Nature Communications
- Maternal intake of methyl-group donors affects DNA methylation of metabolic genes in infants
- (2017) Sara Pauwels et al. Clinical Epigenetics
- Biological Age Predictors
- (2017) Juulia Jylhävä et al. EBioMedicine
- A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs
- (2017) Silvan R. Urfer et al. GeroScience
- Aging across the tree of life: The importance of a comparative perspective for the use of animal models in aging
- (2017) Alan A. Cohen BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Short-term calorie restriction ameliorates genomewide, age-related alterations in DNA methylation
- (2016) Chul Hong Kim et al. AGING CELL
- Aging: progressive decline in fitness due to the rising deleteriome adjusted by genetic, environmental, and stochastic processes
- (2016) Vadim N. Gladyshev AGING CELL
- Specific premature epigenetic aging of cartilage in osteoarthritis
- (2016) Laura Vidal-Bralo et al. Aging-US
- Rapamycin treatment benefits glucose metabolism in mouse models of type 2 diabetes
- (2016) Peter C. Reifsnyder et al. Aging-US
- DNA methylation-based measures of biological age: meta-analysis predicting time to death
- (2016) Brian H. Chen et al. Aging-US
- DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
- (2016) Bonnie R. Joubert et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Reference-free deconvolution of DNA methylation data and mediation by cell composition effects
- (2016) E. Andres Houseman et al. BMC BIOINFORMATICS
- Hepatic NAD+deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing
- (2016) Can-Can Zhou et al. BRITISH JOURNAL OF PHARMACOLOGY
- DNA Methylation in Cancer and Aging
- (2016) M. Klutstein et al. CANCER RESEARCH
- Metabolic Control of Longevity
- (2016) Carlos López-Otín et al. CELL
- Exercise Promotes Healthy Aging of Skeletal Muscle
- (2016) Gregory D. Cartee et al. Cell Metabolism
- Epigenome Maintenance in Response to DNA Damage
- (2016) Juliette Dabin et al. MOLECULAR CELL
- The Aging Epigenome
- (2016) Lauren N. Booth et al. MOLECULAR CELL
- Interplay between Metabolism and Epigenetics: A Nuclear Adaptation to Environmental Changes
- (2016) Jean-Pierre Etchegaray et al. MOLECULAR CELL
- Disease variants alter transcription factor levels and methylation of their binding sites
- (2016) Marc Jan Bonder et al. NATURE GENETICS
- Cardioprotection and lifespan extension by the natural polyamine spermidine
- (2016) Tobias Eisenberg et al. NATURE MEDICINE
- Transcriptional architecture of the mammalian circadian clock
- (2016) Joseph S. Takahashi NATURE REVIEWS GENETICS
- DNA methylation in human epigenomes depends on local topology of CpG sites
- (2016) Cecilia Lövkvist et al. NUCLEIC ACIDS RESEARCH
- Specific increase of methylation age in osteoarthritis cartilage
- (2016) L. Vidal et al. OSTEOARTHRITIS AND CARTILAGE
- Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice
- (2016) Niran Hadad et al. Epigenetics & Chromatin
- DNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer
- (2016) Andrew E Teschendorff et al. Nature Communications
- Genetic and environmental influences interact with age and sex in shaping the human methylome
- (2016) Jenny van Dongen et al. Nature Communications
- Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes
- (2016) Karl Bacos et al. Nature Communications
- Metformin: A Hopeful Promise in Aging Research
- (2016) Marta G. Novelle et al. Cold Spring Harbor Perspectives in Medicine
- Epigenome-wide Association Studies and the Interpretation of Disease -Omics
- (2016) Ewan Birney et al. PLoS Genetics
- Ultraviolet-B induces ERCC6 repression in lens epithelium cells of age-related nuclear cataract through coordinated DNA hypermethylation and histone deacetylation
- (2016) Yong Wang et al. Clinical Epigenetics
- Frailty is associated with the epigenetic clock but not with telomere length in a German cohort
- (2016) Lutz Philipp Breitling et al. Clinical Epigenetics
- DNA methylation and healthy human aging
- (2015) Meaghan J. Jones et al. AGING CELL
- Metabolic consequences of long-term rapamycin exposure on common marmoset monkeys (Callithrix jacchus)
- (2015) Corinna Ross et al. Aging-US
- Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning
- (2015) Morgan E Levine et al. Aging-US
- Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patients
- (2015) Steve Horvath et al. Aging-US
- DNA methylation age of blood predicts future onset of lung cancer in the women's health initiative
- (2015) Morgan E. Levine et al. Aging-US
- Aging and DNA methylation
- (2015) Marc Jung et al. BMC BIOLOGY
- Genome-wide DNA methylation study of hip and knee cartilage reveals embryonic organ and skeletal system morphogenesis as major pathways involved in osteoarthritis
- (2015) Erfan Aref-Eshghi et al. BMC MUSCULOSKELETAL DISORDERS
- Defects of mutant DNMT1 are linked to a spectrum of neurological disorders
- (2015) Jonathan Baets et al. BRAIN
- Circadian Clock Control by Polyamine Levels through a Mechanism that Declines with Age
- (2015) Ziv Zwighaft et al. Cell Metabolism
- Sirtuins in Epigenetic Regulation
- (2015) Hui Jing et al. CHEMICAL REVIEWS
- Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity
- (2015) Douglas R. Seals et al. JOURNAL OF PHYSIOLOGY-LONDON
- Probe Lasso: A novel method to rope in differentially methylated regions with 450K DNA methylation data
- (2015) Lee M. Butcher et al. METHODS
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Ribosomal frameshifting and dual-target antiactivation restrict quorum-sensing–activated transfer of a mobile genetic element
- (2015) Joshua P. Ramsay et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences
- (2015) Xiao-Hong Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mismatch repair proteins recruit DNA methyltransferase 1 to sites of oxidative DNA damage
- (2015) Ning Ding et al. Journal of Molecular Cell Biology
- An Integrative Multi-scale Analysis of the Dynamic DNA Methylation Landscape in Aging
- (2015) Tian Yuan et al. PLoS Genetics
- Correlation of Smoking-Associated DNA Methylation Changes in Buccal Cells With DNA Methylation Changes in Epithelial Cancer
- (2015) Andrew E. Teschendorff et al. JAMA Oncology
- Regularization Paths for Generalized Linear Models via Coordinate Descent
- (2015) Jerome Friedman et al. Journal of Statistical Software
- Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays
- (2014) Martin J. Aryee et al. BIOINFORMATICS
- Lifespan extension and cancer prevention in HER-2/neu transgenic mice treated with low intermittent doses of rapamycin
- (2014) Irina G Popovich et al. CANCER BIOLOGY & THERAPY
- Locally Disordered Methylation Forms the Basis of Intratumor Methylome Variation in Chronic Lymphocytic Leukemia
- (2014) Dan A. Landau et al. CANCER CELL
- DNA Damage Response and Metabolic Disease
- (2014) Ippei Shimizu et al. Cell Metabolism
- Krebs cycle dysfunction shapes epigenetic landscape of chromatin: Novel insights into mitochondrial regulation of aging process
- (2014) Antero Salminen et al. CELLULAR SIGNALLING
- Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation
- (2014) Loukia G Tsaprouni et al. Epigenetics
- Dietary fat quality impacts genome-wide DNA methylation patterns in a cross-sectional study of Greek preadolescents
- (2014) Sarah Voisin et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells
- (2014) Agustín F. Fernández et al. GENOME RESEARCH
- Aging and epigenetic drift: a vicious cycle
- (2014) Jean-Pierre Issa JOURNAL OF CLINICAL INVESTIGATION
- Circadian behavior is light-reprogrammed by plastic DNA methylation
- (2014) Abdelhalim Azzi et al. NATURE NEUROSCIENCE
- Economic and social implications of aging societies
- (2014) S. Harper SCIENCE
- mTOR inhibition improves immune function in the elderly
- (2014) J. B. Mannick et al. Science Translational Medicine
- NAD+ and sirtuins in aging and disease
- (2014) Shin-ichiro Imai et al. TRENDS IN CELL BIOLOGY
- DNA Methylation in Mammals
- (2014) E. Li et al. Cold Spring Harbor Perspectives in Biology
- Genome-Wide DNA Methylation Analysis of Human Pancreatic Islets from Type 2 Diabetic and Non-Diabetic Donors Identifies Candidate Genes That Influence Insulin Secretion
- (2014) Tasnim Dayeh et al. PLoS Genetics
- We Are Ageing
- (2014) Genovefa D. Kolovou et al. Biomed Research International
- Differences in smoking associated DNA methylation patterns in South Asians and Europeans
- (2014) Hannah R Elliott et al. Clinical Epigenetics
- Accounting for cellular heterogeneity is critical in epigenome-wide association studies
- (2014) Andrew E Jaffe et al. GENOME BIOLOGY
- Genome-wide DNA methylation analysis of articular chondrocytes reveals a cluster of osteoarthritic patients
- (2013) Juan Fernández-Tajes et al. ANNALS OF THE RHEUMATIC DISEASES
- Identifying the genomic determinants of aging and longevity in human population studies: Progress and challenges
- (2013) Joris Deelen et al. BIOESSAYS
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Chromatin modifications during repair of environmental exposure-induced DNA damage: A potential mechanism for stable epigenetic alterations
- (2013) Heather M. O'Hagan ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Age-associated epigenetic drift: implications, and a case of epigenetic thrift?
- (2013) A. E. Teschendorff et al. HUMAN MOLECULAR GENETICS
- Rapamycin extends murine lifespan but has limited effects on aging
- (2013) Frauke Neff et al. JOURNAL OF CLINICAL INVESTIGATION
- Discovering high-resolution patterns of differential DNA methylation that correlate with gene expression changes
- (2013) Nathan D. VanderKraats et al. NUCLEIC ACIDS RESEARCH
- Collaboration between CpG sites is needed for stable somatic inheritance of DNA methylation states
- (2013) Jan O. Haerter et al. NUCLEIC ACIDS RESEARCH
- Increased Polyamine Intake Inhibits Age-Associated Alteration in Global DNA Methylation and 1,2-Dimethylhydrazine-Induced Tumorigenesis
- (2013) Kuniyasu Soda et al. PLoS One
- Distinctive topology of age-associated epigenetic drift in the human interactome
- (2013) J. West et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The DNA Methylome As A Biomarker for Epigenetic Instability and Human Aging
- (2013) Andrew R. Mendelsohn et al. REJUVENATION RESEARCH
- Global Epigenomic Reconfiguration During Mammalian Brain Development
- (2013) R. Lister et al. SCIENCE
- Aging is associated with highly defined epigenetic changes in the human epidermis
- (2013) Günter Raddatz et al. Epigenetics & Chromatin
- Role of DNA Methylation and Epigenetic Silencing of HAND2 in Endometrial Cancer Development
- (2013) Allison Jones et al. PLOS MEDICINE
- Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape
- (2013) Kenneth Day et al. GENOME BIOLOGY
- DNA methylation age of human tissues and cell types
- (2013) Steve Horvath GENOME BIOLOGY
- Epigenetic variation during the adult lifespan: cross-sectional and longitudinal data on monozygotic twin pairs
- (2012) Rudolf P. Talens et al. AGING CELL
- Rapamycin slows aging in mice
- (2012) John E. Wilkinson et al. AGING CELL
- Genome-wide profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis
- (2012) Jesús Delgado-Calle et al. ARTHRITIS AND RHEUMATISM
- Comb-p: software for combining, analyzing, grouping and correcting spatially correlated P-values
- (2012) B. S. Pedersen et al. BIOINFORMATICS
- Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle
- (2012) Romain Barrès et al. Cell Metabolism
- Bump hunting to identify differentially methylated regions in epigenetic epidemiology studies
- (2012) Andrew E Jaffe et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates
- (2012) Gregory Hannum et al. MOLECULAR CELL
- Epigenetics and the environment: emerging patterns and implications
- (2012) Robert Feil et al. NATURE REVIEWS GENETICS
- Functions of DNA methylation: islands, start sites, gene bodies and beyond
- (2012) Peter A. Jones NATURE REVIEWS GENETICS
- Age-Associated Changes In Oxidative Stress and NAD+ Metabolism In Human Tissue
- (2012) Hassina Massudi et al. PLoS One
- Distinct DNA methylomes of newborns and centenarians
- (2012) H. Heyn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epigenetic variability in cells of normal cytology is associated with the risk of future morphological transformation
- (2012) Andrew E Teschendorff et al. Genome Medicine
- Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population
- (2012) Jordana T. Bell et al. PLoS Genetics
- Aging effects on DNA methylation modules in human brain and blood tissue
- (2012) Steve Horvath et al. GENOME BIOLOGY
- Oxidative Damage Targets Complexes Containing DNA Methyltransferases, SIRT1, and Polycomb Members to Promoter CpG Islands
- (2011) Heather M. O'Hagan et al. CANCER CELL
- Increased methylation variation in epigenetic domains across cancer types
- (2011) Kasper Daniel Hansen et al. NATURE GENETICS
- Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss
- (2011) Christopher J Klein et al. NATURE GENETICS
- Epigenetic Predictor of Age
- (2011) Sven Bocklandt et al. PLoS One
- Identification of Type 1 Diabetes–Associated DNA Methylation Variable Positions That Precede Disease Diagnosis
- (2011) Vardhman K. Rakyan et al. PLoS Genetics
- DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
- (2011) Jordana T Bell et al. GENOME BIOLOGY
- Tissue-specific dysregulation of DNA methylation in aging
- (2010) Reid F. Thompson et al. AGING CELL
- METAL: fast and efficient meta-analysis of genomewide association scans
- (2010) C. J. Willer et al. BIOINFORMATICS
- PARP around the Clock
- (2010) Vivek Kumar et al. CELL
- Poly(ADP-Ribose) Polymerase 1 Participates in the Phase Entrainment of Circadian Clocks to Feeding
- (2010) Gad Asher et al. CELL
- Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer
- (2010) A. E. Teschendorff et al. GENOME RESEARCH
- Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains
- (2010) V. K. Rakyan et al. GENOME RESEARCH
- Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine
- (2010) Seung-Gi Jin et al. NUCLEIC ACIDS RESEARCH
- Differential DNA Methylation Correlates with Differential Expression of Angiogenic Factors in Human Heart Failure
- (2010) Mehregan Movassagh et al. PLoS One
- The Behaviour of 5-Hydroxymethylcytosine in Bisulfite Sequencing
- (2010) Yun Huang et al. PLoS One
- Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease
- (2010) Patricia Spilman et al. PLoS One
- SIRT1-dependent regulation of chromatin and transcription: Linking NAD+ metabolism and signaling to the control of cellular functions
- (2009) Tong Zhang et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
- (2009) David E. Harrison et al. NATURE
- Aging and Environmental Exposures Alter Tissue-Specific DNA Methylation Dependent upon CpG Island Context
- (2009) Brock C. Christensen et al. PLoS Genetics
- A seat at the table
- (2009) Gregory A Petsko GENOME BIOLOGY
- WGCNA: an R package for weighted correlation network analysis
- (2008) Peter Langfelder et al. BMC BIOINFORMATICS
- SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging
- (2008) Philipp Oberdoerffer et al. CELL
- Double Strand Breaks Can Initiate Gene Silencing and SIRT1-Dependent Onset of DNA Methylation in an Exogenous Promoter CpG Island
- (2008) Heather M. O'Hagan et al. PLoS Genetics
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More