标题
Rapamycin extends murine lifespan but has limited effects on aging
作者
关键词
-
出版物
JOURNAL OF CLINICAL INVESTIGATION
Volume 123, Issue 8, Pages 3272-3291
出版商
American Society for Clinical Investigation
发表日期
2013-07-25
DOI
10.1172/jci67674
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Rapamycin slows aging in mice
- (2012) John E. Wilkinson et al. AGING CELL
- Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice
- (2012) Vladimir N. Anisimov et al. CELL CYCLE
- Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice
- (2012) J. Halloran et al. NEUROSCIENCE
- Adult-Onset Fluoxetine Treatment Does Not Improve Behavioral Impairments and May Have Adverse Effects on the Ts65Dn Mouse Model of Down Syndrome
- (2012) Markus Heinen et al. NEURAL PLASTICITY
- Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling
- (2011) Smita Majumder et al. AGING CELL
- Chronic mTOR inhibition by rapamycin induces muscle insulin resistance despite weight loss in rats
- (2011) N Deblon et al. BRITISH JOURNAL OF PHARMACOLOGY
- mTOR inhibition and erythropoiesis: microcytosis or anaemia?
- (2011) F. Diekmann et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Rapamycin Extends Maximal Lifespan in Cancer-Prone Mice
- (2010) Vladimir N. Anisimov et al. AMERICAN JOURNAL OF PATHOLOGY
- Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production
- (2010) S. Zhang et al. BLOOD
- Rapamycin increases the yield and effector function of human γδ T cells stimulated in vitro
- (2010) Haishan Li et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Loss of Inhibitory Insulin Receptor Substrate-1 Phosphorylation Is an Early Event in Mammalian Target of Rapamycin-Dependent Endometrial Hyperplasia and Carcinoma
- (2010) A. S. McCampbell et al. Cancer Prevention Research
- With TOR, Less Is More: A Key Role for the Conserved Nutrient-Sensing TOR Pathway in Aging
- (2010) Pankaj Kapahi et al. Cell Metabolism
- Chronic Rapamycin Treatment Causes Glucose Intolerance and Hyperlipidemia by Upregulating Hepatic Gluconeogenesis and Impairing Lipid Deposition in Adipose Tissue
- (2010) V. P. Houde et al. DIABETES
- Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice
- (2010) Richard A. Miller et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Mouse phenotyping
- (2010) Helmut Fuchs et al. METHODS
- Cardiac Aging in Mice and Humans: The Role of Mitochondrial Oxidative Stress
- (2010) Dao-Fu Dai et al. TRENDS IN CARDIOVASCULAR MEDICINE
- An Emerging Role of mTOR in Lipid Biosynthesis
- (2009) Mathieu Laplante et al. CURRENT BIOLOGY
- Echocardiographic assessment of global left ventricular function in mice
- (2009) Jörg Stypmann et al. LABORATORY ANIMALS
- Noninvasive, In Vivo Assessment of Mouse Retinal Structure Using Optical Coherence Tomography
- (2009) M. Dominik Fischer et al. PLoS One
- Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span
- (2009) C. Selman et al. SCIENCE
- mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells
- (2009) C. Chen et al. Science Signaling
- Low-dose aspirin prevents age-related endothelial dysfunction in a mouse model of physiological aging
- (2008) Hélène Bulckaen et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
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