标题
mTOR inhibition improves immune function in the elderly
作者
关键词
-
出版物
Science Translational Medicine
Volume 6, Issue 268, Pages 268ra179-268ra179
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2014-12-25
DOI
10.1126/scitranslmed.3009892
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice
- (2014) Mitchell Barns et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- NFATc1 Regulates PD-1 Expression upon T Cell Activation
- (2014) K. J. Oestreich et al. JOURNAL OF IMMUNOLOGY
- Late-life rapamycin treatment reverses age-related heart dysfunction
- (2013) James M. Flynn et al. AGING CELL
- The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus
- (2013) Rachael Keating et al. NATURE IMMUNOLOGY
- Human circulating influenza-CD4+ ICOS1+IL-21+ T cells expand after vaccination, exert helper function, and predict antibody responses
- (2013) F. Spensieri et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Preserving Youth: Does Rapamycin Deliver?
- (2013) S. C. Johnson et al. Science Translational Medicine
- The Gracefully Aging Immune System
- (2013) D. Boraschi et al. Science Translational Medicine
- Rapamycin slows aging in mice
- (2012) John E. Wilkinson et al. AGING CELL
- Viral acute lower respiratory infections impair CD8+ T cells through PD-1
- (2012) John J. Erickson et al. JOURNAL OF CLINICAL INVESTIGATION
- Partial restoration of T-cell function in aged mice by in vitro blockade of the PD-1/ PD-L1 pathway
- (2010) Celine S. Lages et al. AGING CELL
- Cutting Edge: Rapamycin Augments Pathogen-Specific but Not Graft-Reactive CD8+ T Cell Responses
- (2010) I. R. Ferrer et al. JOURNAL OF IMMUNOLOGY
- mTOR regulates memory CD8 T-cell differentiation
- (2009) Koichi Araki et al. NATURE
- Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
- (2009) David E. Harrison et al. NATURE
- PD-1+ memory phenotype CD4+ T cells expressing C/EBP underlie T cell immunodepression in senescence and leukemia
- (2009) K. Shimatani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells
- (2009) C. Chen et al. Science Signaling
- Identifying Optimal Biologic Doses of Everolimus (RAD001) in Patients With Cancer Based on the Modeling of Preclinical and Clinical Pharmacokinetic and Pharmacodynamic Data
- (2008) Chiaki Tanaka et al. JOURNAL OF CLINICAL ONCOLOGY
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