标题
Epigenetic clocks reveal a rejuvenation event during embryogenesis followed by aging
作者
关键词
-
出版物
Science Advances
Volume 7, Issue 26, Pages eabg6082
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2021-06-26
DOI
10.1126/sciadv.abg6082
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells
- (2020) Tapash Jay Sarkar et al. Nature Communications
- Biohorology and biomarkers of aging: Current state-of-the-art, challenges and opportunities
- (2020) Fedor Galkin et al. AGEING RESEARCH REVIEWS
- Spatiotemporal DNA methylome dynamics of the developing mouse fetus
- (2020) Yupeng He et al. NATURE
- Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity
- (2020) Thomas Dahlet et al. Nature Communications
- The Ground Zero of Organismal Life and Aging
- (2020) Vadim N. Gladyshev TRENDS IN MOLECULAR MEDICINE
- Reprogramming to recover youthful epigenetic information and restore vision
- (2020) Yuancheng Lu et al. NATURE
- DNA methylation GrimAge strongly predicts lifespan and healthspan
- (2019) Ake T. Lu et al. Aging-US
- Ribosomal DNA harbors an evolutionarily conserved clock of biological aging
- (2019) Meng Wang et al. GENOME RESEARCH
- Mice with hyper-long telomeres show less metabolic aging and longer lifespans
- (2019) Miguel A. Muñoz-Lorente et al. Nature Communications
- Multi-omics profiling of mouse gastrulation at single-cell resolution
- (2019) Ricard Argelaguet et al. NATURE
- Patterns of Aging Biomarkers, Mortality, and Damaging Mutations Illuminate the Beginning of Aging and Causes of Early-Life Mortality
- (2019) Elvira D. Kinzina et al. Cell Reports
- Global remodeling of the mouse DNA methylome during aging and in response to calorie restriction
- (2018) András Sziráki et al. AGING CELL
- An epigenetic biomarker of aging for lifespan and healthspan
- (2018) Morgan E. Levine et al. Aging-US
- Reprogramming of H3K9me3-dependent heterochromatin during mammalian embryo development
- (2018) Chenfei Wang et al. NATURE CELL BIOLOGY
- DNA methylation-based biomarkers and the epigenetic clock theory of ageing
- (2018) Steve Horvath et al. NATURE REVIEWS GENETICS
- Epigenetic age-predictor for mice based on three CpG sites
- (2018) Yang Han et al. eLife
- Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity
- (2018) Nelly Olova et al. AGING CELL
- A multi-tissue full lifespan epigenetic clock for mice
- (2018) Michael J. Thompson et al. Aging-US
- Paternal germ line aging: DNA methylation age prediction from human sperm
- (2018) Timothy G. Jenkins et al. BMC GENOMICS
- A whole lifespan mouse multi-tissue DNA methylation clock
- (2018) Margarita V Meer et al. eLife
- Individual CpG sites that are associated with age and life expectancy become hypomethylated upon aging
- (2017) Yan Zhang et al. Clinical Epigenetics
- Aging: progressive decline in fitness due to the rising deleteriome adjusted by genetic, environmental, and stochastic processes
- (2016) Vadim N. Gladyshev AGING CELL
- DNA methylation levels at individual age-associated CpG sites can be indicative for life expectancy
- (2016) Qiong Lin et al. Aging-US
- In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming
- (2016) Alejandro Ocampo et al. CELL
- Tankyrase inhibition promotes a stable human naïve pluripotent state with improved functionality
- (2016) Ludovic Zimmerlin et al. DEVELOPMENT
- Nucleolar organizer regions: genomic ‘dark matter’ requiring illumination
- (2016) Brian McStay GENES & DEVELOPMENT
- The Aging Epigenome
- (2016) Lauren N. Booth et al. MOLECULAR CELL
- TET-mediated DNA demethylation controls gastrulation by regulating Lefty–Nodal signalling
- (2016) Hai-Qiang Dai et al. NATURE
- Profiling placental and fetal DNA methylation in human neural tube defects
- (2016) E. Magda Price et al. Epigenetics & Chromatin
- Frailty is associated with the epigenetic clock but not with telomere length in a German cohort
- (2016) Lutz Philipp Breitling et al. Clinical Epigenetics
- Accelerated epigenetic aging in Down syndrome
- (2015) Steve Horvath et al. AGING CELL
- Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patients
- (2015) Steve Horvath et al. Aging-US
- The mechanism of ageing: primary role of transposable elements in genome disintegration
- (2015) Ádám Sturm et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Epigenetic age signatures in the forensically relevant body fluid of semen: a preliminary study
- (2015) Hwan Young Lee et al. Forensic Science International-Genetics
- Methylomic trajectories across human fetal brain development
- (2015) Helen Spiers et al. GENOME RESEARCH
- The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936
- (2015) Riccardo E Marioni et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Machine learning: Trends, perspectives, and prospects
- (2015) M. I. Jordan et al. SCIENCE
- DNA Methylation Landscapes of Human Fetal Development
- (2015) Roderick C. Slieker et al. PLoS Genetics
- DNA methylation age of blood predicts all-cause mortality in later life
- (2015) Riccardo E Marioni et al. GENOME BIOLOGY
- Programming and Inheritance of Parental DNA Methylomes in Mammals
- (2014) Lu Wang et al. CELL
- DNA methylation dynamics of the human preimplantation embryo
- (2014) Zachary D. Smith et al. NATURE
- Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential
- (2014) M. Ohnuki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Single-Cell RNA-Seq Reveals Dynamic, Random Monoallelic Gene Expression in Mammalian Cells
- (2014) Q. Deng et al. SCIENCE
- Timing of developmental events in the early mouse embryo
- (2014) Yoji Kojima et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Age-Associated Sperm DNA Methylation Alterations: Possible Implications in Offspring Disease Susceptibility
- (2014) Timothy G. Jenkins et al. PLoS Genetics
- Aging of blood can be tracked by DNA methylation changes at just three CpG sites
- (2014) Carola Weidner et al. GENOME BIOLOGY
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Comparison of the molecular profiles of human embryonic and induced pluripotent stem cells of isogenic origin
- (2013) Barbara S. Mallon et al. Stem Cell Research
- DNA methylation age of human tissues and cell types
- (2013) Steve Horvath GENOME BIOLOGY
- Aging, Rejuvenation, and Epigenetic Reprogramming: Resetting the Aging Clock
- (2012) Thomas A. Rando et al. CELL
- Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and Their Differentiated Derivatives
- (2012) Kristopher L. Nazor et al. Cell Stem Cell
- Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates
- (2012) Gregory Hannum et al. MOLECULAR CELL
- A unique regulatory phase of DNA methylation in the early mammalian embryo
- (2012) Zachary D. Smith et al. NATURE
- Conversion of human fibroblasts to angioblast-like progenitor cells
- (2012) Leo Kurian et al. NATURE METHODS
- StemCellDB: The Human Pluripotent Stem Cell Database at the National Institutes of Health
- (2012) Barbara S. Mallon et al. Stem Cell Research
- The Combination of Inhibitors of FGF/MEK/Erk and GSK3β Signaling Increases the Number of OCT3/4- and NANOG-Positive Cells in the Human Inner Cell Mass, But Does Not Improve Stem Cell Derivation
- (2012) Margot Van der Jeught et al. STEM CELLS AND DEVELOPMENT
- Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications
- (2011) Felix Krueger et al. BIOINFORMATICS
- Open-Ended Question: Is Immortality Exclusively Inherent to the Germline? – A Mini-Review
- (2008) Günter Lepperdinger GERONTOLOGY
- Effect of parental ageing on offspring developmental and survival attributes in an aphidophagous ladybird,Cheilomenes sexmaculata
- (2008) K. Singh et al. JOURNAL OF APPLIED ENTOMOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now