Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape

DNA Methylation Signatures in Development and Aging of the Human Prefrontal Cortex

(2012) Shusuke Numata et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Regulated Noise in the Epigenetic Landscape of Development and Disease

(2012) Elisabet Pujadas et al.   CELL

CTCF: insights into insulator function during development

(2012) M. Herold et al.   DEVELOPMENT

Widespread plasticity in CTCF occupancy linked to DNA methylation

(2012) H. Wang et al.   GENOME RESEARCH

Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

(2012) Gregory Hannum et al.   MOLECULAR CELL

A unique regulatory phase of DNA methylation in the early mammalian embryo

(2012) Zachary D. Smith et al.   NATURE

ChromHMM: automating chromatin-state discovery and characterization

(2012) Jason Ernst et al.   NATURE METHODS

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Distinct DNA methylomes of newborns and centenarians

(2012) H. Heyn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA Methylation

(2012) J. Song et al.   SCIENCE

Linking DNA Methyltransferases to Epigenetic Marks and Nucleosome Structure Genome-wide in Human Tumor Cells

(2012) Bilian Jin et al.   Cell Reports

Genome-wide promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging

(2011) M. T. Bocker et al.   BLOOD

Batch effect correction for genome-wide methylation data with Illumina Infinium platform

(2011) Zhifu Sun et al.   BMC Medical Genomics

Epigenetic signatures distinguish multiple classes of enhancers with distinct cellular functions

(2011) Gabriel E. Zentner et al.   GENOME RESEARCH

Distinct DNA methylation changes highly correlated with chronological age in the human brain

(2011) Dena G. Hernandez et al.   HUMAN MOLECULAR GENETICS

Fibrosis, Regeneration, and Aging: Playing Chess with Evolution

(2011) V. E. Torres et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Neuronal activity modifies the DNA methylation landscape in the adult brain

(2011) Junjie U Guo et al.   NATURE NEUROSCIENCE

Specific Age-Associated DNA Methylation Changes in Human Dermal Fibroblasts

(2011) Carmen M. Koch et al.   PLoS One

Tissue-specific dysregulation of DNA methylation in aging

(2010) Reid F. Thompson et al.   AGING CELL

Aging and its effects on inflammation in skeletal muscle at rest and following exercise-induced muscle injury

(2010) Jonathan Peake et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Distinct Epigenomic Landscapes of Pluripotent and Lineage-Committed Human Cells

(2010) R. David Hawkins et al.   Cell Stem Cell

Aberrant Epigenetic Landscape in Cancer: How Cellular Identity Goes Awry

(2010) María Berdasco et al.   DEVELOPMENTAL CELL

Regulation and dysregulation of fibrosis in skeletal muscle

(2010) Antonio L. Serrano et al.   EXPERIMENTAL CELL RESEARCH

Every methyl counts - Epigenetic calculus

(2010) Annette N.D. Scharf et al.   FEBS LETTERS

Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer

(2010) A. E. Teschendorff et al.   GENOME RESEARCH

Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains

(2010) V. K. Rakyan et al.   GENOME RESEARCH

Widespread and tissue specific age-related DNA methylation changes in mice

(2010) S. Maegawa et al.   GENOME RESEARCH

Dynamic changes in the human methylome during differentiation

(2010) L. Laurent et al.   GENOME RESEARCH

DNMT1 maintains progenitor function in self-renewing somatic tissue

(2010) George L. Sen et al.   NATURE

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic gambling and epigenetic drift as an antagonistic pleiotropic mechanism of aging

(2009) George M. Martin   AGING CELL

DNA methylation pattern changes upon long-term culture and aging of human mesenchymal stromal cells

(2009) Simone Bork et al.   AGING CELL

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Interaction between the inner nuclear membrane lamin B receptor and the heterochromatic methyl binding protein, MeCP2

(2009) Alessia Guarda et al.   EXPERIMENTAL CELL RESEARCH

Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

(2009) Akiko Doi et al.   NATURE GENETICS

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction

(2009) Ann-Marie Bröske et al.   NATURE GENETICS

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

(2009) Rafael A Irizarry et al.   NATURE GENETICS

Aging and Environmental Exposures Alter Tissue-Specific DNA Methylation Dependent upon CpG Island Context

(2009) Brock C. Christensen et al.   PLoS Genetics

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

(2008) Lars Guelen et al.   NATURE

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH