Mitochondrial dysfunction and mitophagy: the beginning and end to diabetic nephropathy?
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Title
Mitochondrial dysfunction and mitophagy: the beginning and end to diabetic nephropathy?
Authors
Keywords
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Journal
BRITISH JOURNAL OF PHARMACOLOGY
Volume 171, Issue 8, Pages 1917-1942
Publisher
Wiley
Online
2013-11-06
DOI
10.1111/bph.12503
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Note: Only part of the references are listed.- Caloric restriction ameliorates kidney ischaemia/reperfusion injury through PGC-1α-eNOS pathway and enhanced autophagy
- (2013) J. Lempiäinen et al. Acta Physiologica
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- (2013) Rudy Bilous ANNALS OF INTERNAL MEDICINE
- Renal Morphologic Lesions Reminiscent of Diabetic Nephropathy
- (2013) Kirtee Raparia et al. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
- IHG-1 must be localised to mitochondria to decrease Smad7 expression and amplify TGF-β1-induced fibrotic responses
- (2013) James B. Corcoran et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Vascular Complications of Diabetes: Mechanisms of Injury and Protective Factors
- (2013) Christian Rask-Madsen et al. Cell Metabolism
- Economic Costs of Diabetes in the U.S. in 2012
- (2013) DIABETES CARE
- Molecular signaling toward mitophagy and its physiological significance
- (2013) Du Feng et al. EXPERIMENTAL CELL RESEARCH
- High glucose induces autophagy in podocytes
- (2013) Tean Ma et al. EXPERIMENTAL CELL RESEARCH
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- (2013) S. Paula-Gomes et al. HORMONE AND METABOLIC RESEARCH
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- (2013) Maurizio Renna et al. HUMAN MOLECULAR GENETICS
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- (2013) Doug-Yoon Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2013) Takako Naito et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2013) Masahiro Iguchi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2013) Michael Lazarou et al. JOURNAL OF CELL BIOLOGY
- The Mitochondrial-Targeted Compound SS-31 Re-Energizes Ischemic Mitochondria by Interacting with Cardiolipin
- (2013) A. V. Birk et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Vps34 Deficiency Reveals the Importance of Endocytosis for Podocyte Homeostasis
- (2013) W. Bechtel et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Metabolomics Reveals Signature of Mitochondrial Dysfunction in Diabetic Kidney Disease
- (2013) K. Sharma et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Mitochondrial dynamics: regulatory mechanisms and emerging role in renal pathophysiology
- (2013) Ming Zhan et al. KIDNEY INTERNATIONAL
- Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
- (2013) Shireen A. Sarraf et al. NATURE
- Autophagy in Human Health and Disease
- (2013) Augustine M.K. Choi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mechanisms of Diabetic Complications
- (2013) Josephine M. Forbes et al. PHYSIOLOGICAL REVIEWS
- Autophagy Attenuates Diabetic Glomerular Damage through Protection of Hyperglycemia-Induced Podocyte Injury
- (2013) Li Fang et al. PLoS One
- Involvement of Endoplasmic Reticulum Stress in Albuminuria Induced Inflammasome Activation in Renal Proximal Tubular Cells
- (2013) Li Fang et al. PLoS One
- Dimers of mitochondrial ATP synthase form the permeability transition pore
- (2013) V. Giorgio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan
- (2013) A. Rana et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria
- (2013) Y. Chen et al. SCIENCE
- The mitochondrial permeability transition pore: a mystery solved?
- (2013) Paolo Bernardi Frontiers in Physiology
- KDOQI Clinical Practice Guideline for Diabetes and CKD: 2012 Update
- (2012) AMERICAN JOURNAL OF KIDNEY DISEASES
- Autophagy Guards Against Cisplatin-Induced Acute Kidney Injury
- (2012) Atsushi Takahashi et al. AMERICAN JOURNAL OF PATHOLOGY
- Loss of calpain 10 causes mitochondrial dysfunction during chronic hyperglycemia
- (2012) Matthew A. Smith et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- MTOR regulates autophagic flux in the glomerulus
- (2012) Davide P. Cinà et al. Autophagy
- A cryptic mitochondrial targeting motif in Atg4D links caspase cleavage with mitochondrial import and oxidative stress
- (2012) Virginie M.S. Betin et al. Autophagy
- Emerging role of autophagy in kidney function, diseases and aging
- (2012) Tobias B. Huber et al. Autophagy
- Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury
- (2012) Shuya Liu et al. Autophagy
- Guidelines for the use and interpretation of assays for monitoring autophagy
- (2012) Daniel J. Klionsky et al. Autophagy
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- (2012) Qiang Zhang et al. BIOCHEMICAL JOURNAL
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- (2012) Magdalena Frank et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Recent advances into the understanding of mitochondrial fission
- (2012) Kirstin Elgass et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
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- (2012) S Shaid et al. CELL DEATH AND DIFFERENTIATION
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- (2012) Sudarsanareddy Lokireddy et al. Cell Metabolism
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- (2012) Wenjian Wang et al. Cell Metabolism
- Mitochondria and Mitophagy
- (2012) Dieter A. Kubli et al. CIRCULATION RESEARCH
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- (2012) Peter Hansell et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
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- (2012) Hemmo Meyer et al. NATURE CELL BIOLOGY
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- (2012) R. Chavez-Valdez et al. NEUROSCIENCE
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- (2012) Emilie Giaime et al. PLoS One
- Bax regulates primary necrosis through mitochondrial dynamics
- (2012) R. S. Whelan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death
- (2012) E. C. Cheung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity
- (2012) D. W. Lamming et al. SCIENCE
- Mitochondrial Fission, Fusion, and Stress
- (2012) R. J. Youle et al. SCIENCE
- Transforming Growth Factor-β, Bioenergetics, and Mitochondria in Renal Disease
- (2012) Gabriella Casalena et al. SEMINARS IN NEPHROLOGY
- Cadmium activates a programmed, lysosomal membrane permeabilization-dependent necrosis pathway
- (2012) Barbara Messner et al. TOXICOLOGY LETTERS
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- (2012) Robin A.J. Smith et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
- (2012) Kahori Shiba-Fukushima et al. Scientific Reports
- PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
- (2012) C. Kondapalli et al. Open Biology
- Regulation of Autophagy by Glucose in Mammalian Cells
- (2012) Félix Moruno et al. Cells
- Mitochondrial autophagy by Bnip3 involves Drp1-mediated mitochondrial fission and recruitment of Parkin in cardiac myocytes
- (2011) Youngil Lee et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Renal oxidative stress, oxygenation, and hypertension
- (2011) Fredrik Palm et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- The proximal tubule in the pathophysiology of the diabetic kidney
- (2011) Volker Vallon AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Long-term Renal Outcomes of Patients With Type 1 Diabetes Mellitus and MicroalbuminuriaAn Analysis of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications CohortMicroalbuminuria Outcomes in Type 1 Diabetes
- (2011) Ian H. de Boer ARCHIVES OF INTERNAL MEDICINE
- Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy
- (2011) Rodrigo Troncoso et al. CARDIOVASCULAR RESEARCH
- PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility
- (2011) Xinnan Wang et al. CELL
- Bnip3 impairs mitochondrial bioenergetics and stimulates mitochondrial turnover
- (2011) S Rikka et al. CELL DEATH AND DIFFERENTIATION
- Autophagic activity in cortical neurons under acute oxidative stress directly contributes to cell death
- (2011) Gavin C. Higgins et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics
- (2011) Jean-Claude Martinou et al. DEVELOPMENTAL CELL
- IDF Diabetes Atlas: Global estimates of the prevalence of diabetes for 2011 and 2030
- (2011) David R. Whiting et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- UV irradiation resistance-associated gene suppresses apoptosis by interfering with BAX activation
- (2011) Xiaocheng Yin et al. EMBO REPORTS
- Dietary Restriction Ameliorates Diabetic Nephropathy through Anti-Inflammatory Effects and Regulation of the Autophagy via Restoration of Sirt1 in Diabetic Wistar Fatty (fa/fa) Rats: A Model of Type 2 Diabetes
- (2011) Munehiro Kitada et al. Experimental Diabetes Research
- Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes
- (2011) Karly C. Sourris et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatin-induced nephropathy
- (2011) Partha Mukhopadhyay et al. FREE RADICAL BIOLOGY AND MEDICINE
- Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy
- (2011) Nickie C. Chan et al. HUMAN MOLECULAR GENETICS
- Mechanisms Involved in the Coordinate Regulation of mTORC1 by Insulin and Amino Acids
- (2011) Michael D. Dennis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of mTOR Kinase by AZD8055 Can Antagonize Chemotherapy-induced Cell Death through Autophagy Induction and Down-regulation of p62/Sequestosome 1
- (2011) Shengbing Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Role of mTOR in podocyte function and diabetic nephropathy in humans and mice
- (2011) Markus Gödel et al. JOURNAL OF CLINICAL INVESTIGATION
- mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice
- (2011) Ken Inoki et al. JOURNAL OF CLINICAL INVESTIGATION
- Mitochondrial reactive oxygen species drive proinflammatory cytokine production: Figure 1.
- (2011) Edwina Naik et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
- (2011) Cathrin Meissner et al. JOURNAL OF NEUROCHEMISTRY
- Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury
- (2011) T. Kimura et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- IHG-1 Promotes Mitochondrial Biogenesis by Stabilizing PGC-1
- (2011) F. B. Hickey et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Inhibition of MTOR Disrupts Autophagic Flux in Podocytes
- (2011) D. P. Cina et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Mitochondria-Targeted Peptide Accelerates ATP Recovery and Reduces Ischemic Kidney Injury
- (2011) H. H. Szeto et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Glucose handling by the kidney
- (2011) Amanda Mather et al. KIDNEY INTERNATIONAL
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- (2011) Assaf D. Rubinstein et al. MOLECULAR CELL
- Oncogenic Ras-Induced Expression of Noxa and Beclin-1 Promotes Autophagic Cell Death and Limits Clonogenic Survival
- (2011) Mohamed Elgendy et al. MOLECULAR CELL
- Cellular and molecular mechanisms of renal fibrosis
- (2011) Youhua Liu Nature Reviews Nephrology
- Pathophysiology of ischemic acute kidney injury
- (2011) Asif A. Sharfuddin et al. Nature Reviews Nephrology
- p32 regulates mitochondrial morphology and dynamics through parkin
- (2011) Y. Li et al. NEUROSCIENCE
- Mutations in PINK1 and Parkin Impair Ubiquitination of Mitofusins in Human Fibroblasts
- (2011) Aleksandar Rakovic et al. PLoS One
- Tubular Overexpression of Transforming Growth Factor-β1 Induces Autophagy and Fibrosis but Not Mesenchymal Transition of Renal Epithelial Cells
- (2010) Robert Koesters et al. AMERICAN JOURNAL OF PATHOLOGY
- ANG II promotes autophagy in podocytes
- (2010) Anju Yadav et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Mitochondrial and Nuclear Cross Talk in Cell Death
- (2010) Shaida A. Andrabi et al. Annals of the New York Academy of Sciences
- The in vitro cleavage of the hAtg proteins by cell death proteases
- (2010) Joanna M. Norman et al. Autophagy
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- (2010) Derek Narendra et al. Autophagy
- Prevention of diabetic nephropathy in Ins2+/−AkitaJmice by the mitochondria-targeted therapy MitoQ
- (2010) Balu K. Chacko et al. BIOCHEMICAL JOURNAL
- ATG12 Conjugation to ATG3 Regulates Mitochondrial Homeostasis and Cell Death
- (2010) Lilliana Radoshevich et al. CELL
- Necroptosis as an alternative form of programmed cell death
- (2010) Dana E Christofferson et al. CURRENT OPINION IN CELL BIOLOGY
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- (2010) Thomas Landes et al. EMBO REPORTS
- Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease
- (2010) C. Rose et al. HUMAN MOLECULAR GENETICS
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- (2010) Matthew E. Gegg et al. HUMAN MOLECULAR GENETICS
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- (2010) Kelly Jean Thomas et al. HUMAN MOLECULAR GENETICS
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- (2010) Kathryn G. Foster et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2010) Ashish Jain et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2010) Wen-Xing Ding et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2010) Atsushi Tanaka et al. JOURNAL OF CELL BIOLOGY
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- (2010) Seok Min Jin et al. JOURNAL OF CELL BIOLOGY
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- (2010) Noriyuki Matsuda et al. JOURNAL OF CELL BIOLOGY
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- (2010) Y.-Y. Park et al. JOURNAL OF CELL SCIENCE
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- (2010) Björn Hartleben et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2010) Rongbin Zhou et al. NATURE
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- (2010) Zhifen Yang et al. NATURE CELL BIOLOGY
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- (2010) Stephen W. G. Tait et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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- (2010) Peter Boor et al. Nature Reviews Nephrology
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- (2010) Y. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2010) E. Ziviani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2009) ARCHIVES OF INTERNAL MEDICINE
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- (2009) L. Zhang et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
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- (2009) H. Fujita et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
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- (2009) T. Ninomiya et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
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- (2009) M. T. Coughlan et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
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- (2009) G. Bellot et al. MOLECULAR AND CELLULAR BIOLOGY
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- (2009) Viktor I. Korolchuk et al. MOLECULAR CELL
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- (2009) Toshio Miyata et al. Nature Reviews Nephrology
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- (2009) Michael Mauer et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2009) Anna Sandebring et al. PLoS One
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- (2009) C. Vives-Bauza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2008) Dieter A. Kubli et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Oxidative Stress and Advanced Glycation in Diabetic Nephropathy
- (2008) Melinda T. Coughlan et al. Annals of the New York Academy of Sciences
- How mitochondria produce reactive oxygen species
- (2008) Michael P. Murphy BIOCHEMICAL JOURNAL
- High levels of Fis1, a pro-fission mitochondrial protein, trigger autophagy
- (2008) Ligia C. Gomes et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway
- (2008) Junichi Hitomi et al. CELL
- Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization
- (2008) Ann Cassidy-Stone et al. DEVELOPMENTAL CELL
- Oxidative Stress as a Major Culprit in Kidney Disease in Diabetes
- (2008) J. M. Forbes et al. DIABETES
- Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
- (2008) Gilad Twig et al. EMBO JOURNAL
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
- Developing Postmitotic Mammalian Neurons In Vivo Lacking Apaf-1 Undergo Programmed Cell Death by a Caspase-Independent, Nonapoptotic Pathway Involving Autophagy
- (2008) R. W. Oppenheim et al. JOURNAL OF NEUROSCIENCE
- Mitochondrial localization of DJ-1 leads to enhanced neuroprotection
- (2008) Eunsung Junn et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Rap1b GTPase Ameliorates Glucose-Induced Mitochondrial Dysfunction
- (2008) L. Sun et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- IHG-1 Amplifies TGF- 1 Signaling and Is Increased in Renal Fibrosis
- (2008) M. Murphy et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Sirolimus Is Associated with New-Onset Diabetes in Kidney Transplant Recipients
- (2008) O. Johnston et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells
- (2008) Sudharsan Periyasamy-Thandavan et al. KIDNEY INTERNATIONAL
- The manganese superoxide dismutase Val16Ala polymorphism is associated with decreased risk of diabetic nephropathy in Chinese patients with type 2 diabetes
- (2008) Limei Liu et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Essential role for Nix in autophagic maturation of erythroid cells
- (2008) Hector Sandoval et al. NATURE
- Genome-Wide and Functional Annotation of Human E3 Ubiquitin Ligases Identifies MULAN, a Mitochondrial E3 that Regulates the Organelle's Dynamics and Signaling
- (2008) Wei Li et al. PLoS One
- Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery
- (2008) Y. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The PINK1/Parkin pathway regulates mitochondrial morphology
- (2008) A. C. Poole et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase
- (2008) M. Saotome et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Renal mitochondrial impairment is attenuated by AT1 blockade in experimental Type I diabetes
- (2007) Elena M. V. de Cavanagh et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Mitochondria-Targeted Cytoprotective Peptides for Ischemia–Reperfusion Injury
- (2007) Hazel H. Szeto ANTIOXIDANTS & REDOX SIGNALING
- The BCL-2 protein family: opposing activities that mediate cell death
- (2007) Richard J. Youle et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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